Leukemic Blasts With Membrane Characteristics Of Either T Or B Cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1974-04

AUTHORS

John M Falletta, Nalini Mukhopadhyay, Kenneth A Starling, Donald J Fernbach, L Leighton Hill

ABSTRACT

Blasts obtained from the diagnostic bone marrow aspiration in 13 children with acute leukemia (excluding acute granulocytic leukemia) were examined for T and B cell membrane characteristics. Blasts accounted for 70-98% (median 92%) of the nucleated cells obtained. Cells were harvested using a sodium metrizoate/Ficoll gradient. Membrane characteristics were assessed by the overnight formation of spontaneous sheep erythrocyte rosettes at 4°C (T cells), and by the presence of membrane-bound immunoglobulin (Ig) and C'3 receptors (B cells). More... »

PAGES

400

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-197404000-00359

DOI

http://dx.doi.org/10.1203/00006450-197404000-00359

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008476472


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