Changes in Nucleic Acid and Protein Content of the Human Brain During Growth View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1968-09

AUTHORS

Myron Winick

ABSTRACT

Extract: In order to establish the pattern of cellular growth, nucleic acid and protein content were serially determined in 31 human brains. The eraliest-material was obtained from a fetus with a gestational age of 13 weeks; the latest from a 13-month-old infant. Weight, protein, and RNA content increased linearly during this period. Weight increased from 5 g to 970 g, protein from 193 mg to 53 g, and RNA from 18.5 to 1384 mg. In contrast, increase in DNA content began to level off at about the time of birth and reached a maximum (approximately 900 mg) by five months of age. These data indicate that very little cell division occurs in the human brain after five months of age and that further growth occurs by increase in protein, RNA and, perhaps, lipid content of cells. More... »

PAGES

352-355

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-196809000-00003

DOI

http://dx.doi.org/10.1203/00006450-196809000-00003

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047635657

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5672695


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