MiRNAs of peripheral blood as the biomarker of schizophrenia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Kuanjun He, Chuang Guo, Lin He, Yongyong Shi

ABSTRACT

The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In the search for new molecular targeted therapy medicines, and recurrence of early-warning indicators have become the major focus of contemporary research, because they improve diagnostic accuracy. Biomarkers reflect the physiological, physical and biochemical status of the body, and so have extensive applicability and practical significance. The ascertainment of schizophrenia biomarkers will help diagnose, stratify of disease, and treat of schizophrenia patients. The detection of biomarkers from blood has become a promising area of schizophrenia research. Recently, a series of studies revealed that, MiRNAs play an important role in the genesis of schizophrenia, and their abnormal expressions have the potential to be used as biomarkers of schizophrenia. This article presents and summarizes the value of peripheral blood miRNAs with abnormal expression as the biomarker of schizophrenia. More... »

PAGES

9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s41065-017-0044-2

DOI

http://dx.doi.org/10.1186/s41065-017-0044-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091371026

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28860957


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "MicroRNAs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Schizophrenia", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Inner Mongolia University for Nationalities", 
          "id": "https://www.grid.ac/institutes/grid.411647.1", 
          "name": [
            "College of Life Science, Inner Mongolia University for Nationalities, 028043, Tongliao, Inner Mongolia, People\u2019s Republic of China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "He", 
        "givenName": "Kuanjun", 
        "id": "sg:person.01150305402.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150305402.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Inner Mongolia University for Nationalities", 
          "id": "https://www.grid.ac/institutes/grid.411647.1", 
          "name": [
            "College of Life Science, Inner Mongolia University for Nationalities, 028043, Tongliao, Inner Mongolia, People\u2019s Republic of China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guo", 
        "givenName": "Chuang", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shanghai Jiao Tong University", 
          "id": "https://www.grid.ac/institutes/grid.16821.3c", 
          "name": [
            "Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), the Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, 200030, Shanghai, People\u2019s Republic of China", 
            "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, People\u2019s Republic of China", 
            "Institute of Neuropsychiatric Science and Systems Biological Medicine, Shanghai Jiao Tong University, 200042, Shanghai, People\u2019s Republic of China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "He", 
        "givenName": "Lin", 
        "id": "sg:person.01341570366.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341570366.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shanghai Jiao Tong University", 
          "id": "https://www.grid.ac/institutes/grid.16821.3c", 
          "name": [
            "Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), the Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, 200030, Shanghai, People\u2019s Republic of China", 
            "Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, People\u2019s Republic of China", 
            "Institute of Neuropsychiatric Science and Systems Biological Medicine, Shanghai Jiao Tong University, 200042, Shanghai, People\u2019s Republic of China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shi", 
        "givenName": "Yongyong", 
        "id": "sg:person.01066657177.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066657177.25"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.schres.2009.01.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000253440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2010.09.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002166736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrrheum.2010.81", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007005111", 
          "https://doi.org/10.1038/nrrheum.2010.81"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrrheum.2010.81", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007005111", 
          "https://doi.org/10.1038/nrrheum.2010.81"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clim.2013.01.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007164291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpsychires.2011.09.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012488697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2010.09.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014187207"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/tp.2016.268", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014295008", 
          "https://doi.org/10.1038/tp.2016.268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.nbd.2011.12.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014401877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(04)16458-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016060837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0021635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017536306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mp.2012.105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019256439", 
          "https://doi.org/10.1038/mp.2012.105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.psc.2007.04.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019470231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/tp.2015.213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019491524", 
          "https://doi.org/10.1038/tp.2015.213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mp.2011.78", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019542389", 
          "https://doi.org/10.1038/mp.2011.78"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2004.12.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020132624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/etm.2014.2014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022127371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/etm.2014.2014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022127371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.b.32109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022928991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.b.32292", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023786186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocn.2014.08.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023903996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20130044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024185730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst20130044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024185730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.nbd.2013.03.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024841756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2217/bmm.13.138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029748348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1192/bjp.bp.113.126979", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029980724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(04)00045-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031254572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2478/v10153-011-0082-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032378950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037192337", 
          "https://doi.org/10.1038/ng1536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037192337", 
          "https://doi.org/10.1038/ng1536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.metabol.2014.10.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037210622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2008.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038602278"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269881114566631", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039892400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269881114566631", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039892400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269881114566631", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039892400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60995-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043412782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mp.2011.170", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043494035", 
          "https://doi.org/10.1038/mp.2011.170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mp.2012.67", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044122748", 
          "https://doi.org/10.1038/mp.2012.67"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.schres.2012.06.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045472541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.schres.2013.11.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046323982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10753-013-9780-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046500287", 
          "https://doi.org/10.1007/s10753-013-9780-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1752-0509-4-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047211846", 
          "https://doi.org/10.1186/1752-0509-4-10"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.brainres.2010.03.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048332713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.expneurol.2014.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051032641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.940", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053172161", 
          "https://doi.org/10.1038/ng.940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.940", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053172161", 
          "https://doi.org/10.1038/ng.940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/appi.ajp.2015.14030273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063500512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1360/052012-402", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1065069834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1503/jpn.130269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067426766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1503/jpn.130269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067426766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076601398", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In the search for new molecular targeted therapy medicines, and recurrence of early-warning indicators have become the major focus of contemporary research, because they improve diagnostic accuracy. Biomarkers reflect the physiological, physical and biochemical status of the body, and so have extensive applicability and practical significance. The ascertainment of schizophrenia biomarkers will help diagnose, stratify of disease, and treat of schizophrenia patients. The detection of biomarkers from blood has become a promising area of schizophrenia research. Recently, a series of studies revealed that, MiRNAs play an important role in the genesis of schizophrenia, and their abnormal expressions have the potential to be used as biomarkers of schizophrenia. This article presents and summarizes the value of peripheral blood miRNAs with abnormal expression as the biomarker of schizophrenia.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s41065-017-0044-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1017631", 
        "issn": [
          "0018-0661", 
          "1601-5223"
        ], 
        "name": "Hereditas", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "155"
      }
    ], 
    "name": "MiRNAs of peripheral blood as the biomarker of schizophrenia", 
    "pagination": "9", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "dde59d050730de327183eb785d9e839200e104590212533bbf1a4bd91be66d67"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28860957"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0374654"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s41065-017-0044-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091371026"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s41065-017-0044-2", 
      "https://app.dimensions.ai/details/publication/pub.1091371026"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:01", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000484.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186/s41065-017-0044-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s41065-017-0044-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s41065-017-0044-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s41065-017-0044-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s41065-017-0044-2'


 

This table displays all metadata directly associated to this object as RDF triples.

249 TRIPLES      21 PREDICATES      76 URIs      25 LITERALS      13 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s41065-017-0044-2 schema:about N0ec74fe3e3d94bf6a8f404864453db63
2 N2c9e48910fa54895b1a6647896833a5d
3 N391c102a4bb249e9a5955b7102e1c35a
4 Nea793933778b4de6a1c879fbc63983e9
5 anzsrc-for:11
6 anzsrc-for:1103
7 schema:author Nb3d927ff592149359554e17fbccd64b4
8 schema:citation sg:pub.10.1007/s10753-013-9780-2
9 sg:pub.10.1038/mp.2011.170
10 sg:pub.10.1038/mp.2011.78
11 sg:pub.10.1038/mp.2012.105
12 sg:pub.10.1038/mp.2012.67
13 sg:pub.10.1038/ng.940
14 sg:pub.10.1038/ng1536
15 sg:pub.10.1038/nrrheum.2010.81
16 sg:pub.10.1038/tp.2015.213
17 sg:pub.10.1038/tp.2016.268
18 sg:pub.10.1186/1752-0509-4-10
19 https://app.dimensions.ai/details/publication/pub.1076601398
20 https://doi.org/10.1002/ajmg.b.32109
21 https://doi.org/10.1002/ajmg.b.32292
22 https://doi.org/10.1016/j.biopsych.2008.11.019
23 https://doi.org/10.1016/j.biopsych.2010.09.030
24 https://doi.org/10.1016/j.biopsych.2010.09.039
25 https://doi.org/10.1016/j.brainres.2010.03.035
26 https://doi.org/10.1016/j.cell.2004.12.035
27 https://doi.org/10.1016/j.clim.2013.01.011
28 https://doi.org/10.1016/j.expneurol.2014.08.005
29 https://doi.org/10.1016/j.jocn.2014.08.018
30 https://doi.org/10.1016/j.jpsychires.2011.09.010
31 https://doi.org/10.1016/j.metabol.2014.10.026
32 https://doi.org/10.1016/j.nbd.2011.12.029
33 https://doi.org/10.1016/j.nbd.2013.03.011
34 https://doi.org/10.1016/j.psc.2007.04.007
35 https://doi.org/10.1016/j.schres.2009.01.022
36 https://doi.org/10.1016/j.schres.2012.06.038
37 https://doi.org/10.1016/j.schres.2013.11.004
38 https://doi.org/10.1016/s0092-8674(04)00045-5
39 https://doi.org/10.1016/s0140-6736(04)16458-1
40 https://doi.org/10.1016/s0140-6736(09)60995-8
41 https://doi.org/10.1042/bst20130044
42 https://doi.org/10.1176/appi.ajp.2015.14030273
43 https://doi.org/10.1177/0269881114566631
44 https://doi.org/10.1192/bjp.bp.113.126979
45 https://doi.org/10.1360/052012-402
46 https://doi.org/10.1371/journal.pone.0021635
47 https://doi.org/10.1503/jpn.130269
48 https://doi.org/10.2217/bmm.13.138
49 https://doi.org/10.2478/v10153-011-0082-x
50 https://doi.org/10.3892/etm.2014.2014
51 schema:datePublished 2018-12
52 schema:datePublishedReg 2018-12-01
53 schema:description The diagnosis of schizophrenia is currently based on the symptoms and bodily signs rather than on the pathological and physiological markers of the patient. In the search for new molecular targeted therapy medicines, and recurrence of early-warning indicators have become the major focus of contemporary research, because they improve diagnostic accuracy. Biomarkers reflect the physiological, physical and biochemical status of the body, and so have extensive applicability and practical significance. The ascertainment of schizophrenia biomarkers will help diagnose, stratify of disease, and treat of schizophrenia patients. The detection of biomarkers from blood has become a promising area of schizophrenia research. Recently, a series of studies revealed that, MiRNAs play an important role in the genesis of schizophrenia, and their abnormal expressions have the potential to be used as biomarkers of schizophrenia. This article presents and summarizes the value of peripheral blood miRNAs with abnormal expression as the biomarker of schizophrenia.
54 schema:genre research_article
55 schema:inLanguage en
56 schema:isAccessibleForFree true
57 schema:isPartOf N7889e7cfaafb4e0298326aeb8e563ab8
58 Nc7e1cc21c9f14599949feb93dcebd427
59 sg:journal.1017631
60 schema:name MiRNAs of peripheral blood as the biomarker of schizophrenia
61 schema:pagination 9
62 schema:productId N4b9b7db1b57743d78d5a7147c513289d
63 N5109fd79d31f4106baaa1dda0c6c554a
64 N5f68d73f304e4e078f494429e2a947d3
65 N6ef86e3724b645028cdc94e2236e9685
66 Ne74b30ef19aa40faadb6e5812d29c0a1
67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091371026
68 https://doi.org/10.1186/s41065-017-0044-2
69 schema:sdDatePublished 2019-04-11T01:01
70 schema:sdLicense https://scigraph.springernature.com/explorer/license/
71 schema:sdPublisher Na535b9cf19ec4102a2b9d37f31ce3f18
72 schema:url http://link.springer.com/10.1186/s41065-017-0044-2
73 sgo:license sg:explorer/license/
74 sgo:sdDataset articles
75 rdf:type schema:ScholarlyArticle
76 N0ec74fe3e3d94bf6a8f404864453db63 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Biomarkers
78 rdf:type schema:DefinedTerm
79 N144ce783213f4153b4958b21ddce716e rdf:first sg:person.01341570366.38
80 rdf:rest N3ed11df8ba6945899a9227914bd1bd57
81 N2c9e48910fa54895b1a6647896833a5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Humans
83 rdf:type schema:DefinedTerm
84 N391c102a4bb249e9a5955b7102e1c35a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Schizophrenia
86 rdf:type schema:DefinedTerm
87 N3b50ec69d07c435fb72786a6c4b733aa schema:affiliation https://www.grid.ac/institutes/grid.411647.1
88 schema:familyName Guo
89 schema:givenName Chuang
90 rdf:type schema:Person
91 N3ed11df8ba6945899a9227914bd1bd57 rdf:first sg:person.01066657177.25
92 rdf:rest rdf:nil
93 N4b9b7db1b57743d78d5a7147c513289d schema:name doi
94 schema:value 10.1186/s41065-017-0044-2
95 rdf:type schema:PropertyValue
96 N5109fd79d31f4106baaa1dda0c6c554a schema:name nlm_unique_id
97 schema:value 0374654
98 rdf:type schema:PropertyValue
99 N5f68d73f304e4e078f494429e2a947d3 schema:name dimensions_id
100 schema:value pub.1091371026
101 rdf:type schema:PropertyValue
102 N6ef86e3724b645028cdc94e2236e9685 schema:name readcube_id
103 schema:value dde59d050730de327183eb785d9e839200e104590212533bbf1a4bd91be66d67
104 rdf:type schema:PropertyValue
105 N7889e7cfaafb4e0298326aeb8e563ab8 schema:issueNumber 1
106 rdf:type schema:PublicationIssue
107 Na535b9cf19ec4102a2b9d37f31ce3f18 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 Nb3d927ff592149359554e17fbccd64b4 rdf:first sg:person.01150305402.38
110 rdf:rest Ne4a1bfc613ca462b9f0ffad0109d8bcc
111 Nc7e1cc21c9f14599949feb93dcebd427 schema:volumeNumber 155
112 rdf:type schema:PublicationVolume
113 Ne4a1bfc613ca462b9f0ffad0109d8bcc rdf:first N3b50ec69d07c435fb72786a6c4b733aa
114 rdf:rest N144ce783213f4153b4958b21ddce716e
115 Ne74b30ef19aa40faadb6e5812d29c0a1 schema:name pubmed_id
116 schema:value 28860957
117 rdf:type schema:PropertyValue
118 Nea793933778b4de6a1c879fbc63983e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name MicroRNAs
120 rdf:type schema:DefinedTerm
121 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
122 schema:name Medical and Health Sciences
123 rdf:type schema:DefinedTerm
124 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
125 schema:name Clinical Sciences
126 rdf:type schema:DefinedTerm
127 sg:journal.1017631 schema:issn 0018-0661
128 1601-5223
129 schema:name Hereditas
130 rdf:type schema:Periodical
131 sg:person.01066657177.25 schema:affiliation https://www.grid.ac/institutes/grid.16821.3c
132 schema:familyName Shi
133 schema:givenName Yongyong
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066657177.25
135 rdf:type schema:Person
136 sg:person.01150305402.38 schema:affiliation https://www.grid.ac/institutes/grid.411647.1
137 schema:familyName He
138 schema:givenName Kuanjun
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150305402.38
140 rdf:type schema:Person
141 sg:person.01341570366.38 schema:affiliation https://www.grid.ac/institutes/grid.16821.3c
142 schema:familyName He
143 schema:givenName Lin
144 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341570366.38
145 rdf:type schema:Person
146 sg:pub.10.1007/s10753-013-9780-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046500287
147 https://doi.org/10.1007/s10753-013-9780-2
148 rdf:type schema:CreativeWork
149 sg:pub.10.1038/mp.2011.170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043494035
150 https://doi.org/10.1038/mp.2011.170
151 rdf:type schema:CreativeWork
152 sg:pub.10.1038/mp.2011.78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019542389
153 https://doi.org/10.1038/mp.2011.78
154 rdf:type schema:CreativeWork
155 sg:pub.10.1038/mp.2012.105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019256439
156 https://doi.org/10.1038/mp.2012.105
157 rdf:type schema:CreativeWork
158 sg:pub.10.1038/mp.2012.67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044122748
159 https://doi.org/10.1038/mp.2012.67
160 rdf:type schema:CreativeWork
161 sg:pub.10.1038/ng.940 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053172161
162 https://doi.org/10.1038/ng.940
163 rdf:type schema:CreativeWork
164 sg:pub.10.1038/ng1536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037192337
165 https://doi.org/10.1038/ng1536
166 rdf:type schema:CreativeWork
167 sg:pub.10.1038/nrrheum.2010.81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007005111
168 https://doi.org/10.1038/nrrheum.2010.81
169 rdf:type schema:CreativeWork
170 sg:pub.10.1038/tp.2015.213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019491524
171 https://doi.org/10.1038/tp.2015.213
172 rdf:type schema:CreativeWork
173 sg:pub.10.1038/tp.2016.268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014295008
174 https://doi.org/10.1038/tp.2016.268
175 rdf:type schema:CreativeWork
176 sg:pub.10.1186/1752-0509-4-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047211846
177 https://doi.org/10.1186/1752-0509-4-10
178 rdf:type schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1076601398 schema:CreativeWork
180 https://doi.org/10.1002/ajmg.b.32109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022928991
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1002/ajmg.b.32292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023786186
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/j.biopsych.2008.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038602278
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.biopsych.2010.09.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002166736
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/j.biopsych.2010.09.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014187207
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.brainres.2010.03.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048332713
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/j.cell.2004.12.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020132624
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/j.clim.2013.01.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007164291
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.expneurol.2014.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051032641
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.jocn.2014.08.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023903996
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/j.jpsychires.2011.09.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012488697
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/j.metabol.2014.10.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037210622
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/j.nbd.2011.12.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014401877
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/j.nbd.2013.03.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024841756
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/j.psc.2007.04.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019470231
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.schres.2009.01.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000253440
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/j.schres.2012.06.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045472541
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/j.schres.2013.11.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046323982
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/s0092-8674(04)00045-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031254572
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/s0140-6736(04)16458-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016060837
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/s0140-6736(09)60995-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043412782
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1042/bst20130044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024185730
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1176/appi.ajp.2015.14030273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063500512
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1177/0269881114566631 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039892400
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1192/bjp.bp.113.126979 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029980724
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1360/052012-402 schema:sameAs https://app.dimensions.ai/details/publication/pub.1065069834
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1371/journal.pone.0021635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017536306
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1503/jpn.130269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067426766
235 rdf:type schema:CreativeWork
236 https://doi.org/10.2217/bmm.13.138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029748348
237 rdf:type schema:CreativeWork
238 https://doi.org/10.2478/v10153-011-0082-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032378950
239 rdf:type schema:CreativeWork
240 https://doi.org/10.3892/etm.2014.2014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022127371
241 rdf:type schema:CreativeWork
242 https://www.grid.ac/institutes/grid.16821.3c schema:alternateName Shanghai Jiao Tong University
243 schema:name Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), the Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, 200030, Shanghai, People’s Republic of China
244 Institute of Neuropsychiatric Science and Systems Biological Medicine, Shanghai Jiao Tong University, 200042, Shanghai, People’s Republic of China
245 Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, People’s Republic of China
246 rdf:type schema:Organization
247 https://www.grid.ac/institutes/grid.411647.1 schema:alternateName Inner Mongolia University for Nationalities
248 schema:name College of Life Science, Inner Mongolia University for Nationalities, 028043, Tongliao, Inner Mongolia, People’s Republic of China
249 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...