Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and V have incision activity on 2,2,4-triamino-5(2H)-oxazolone View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-11-01

AUTHORS

Katsuhito Kino, Masayo Suzuki, Masayuki Morikawa, Takanobu Kobayashi, Shigenori Iwai, Hiroshi Miyazawa

ABSTRACT

Introduction2,2,4-Triamino-5(2H)-oxazolone (Oz) in a DNA strand is an oxidation product of guanine and 8-oxo-7, 8-dihydroguanine, and such a lesion can cause G-to-C transversions. Previously, Fpg/Nei and Nth were shown to have incision activity on Oz.FindingsWe investigated the activities of chlorella virus pyrimidine dimer glycosylase (cvPDG) and Escherichia coli endonucleases IV (Nfo) and V (Nfi) on Oz. Although the three enzymes have different repair mechanisms from Fpg/Nei and Nth, they still had incision activity on Oz.ConclusionsGiven the incision activities of cvPDG, Nfo and Nfi on Oz in addition to Fpg/Nei and Nth, Oz is DNA damage that can be repaired by diverse enzymes. More... »

PAGES

22

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s41021-015-0022-8

DOI

http://dx.doi.org/10.1186/s41021-015-0022-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051025308

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27350817


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Microbiology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kino", 
        "givenName": "Katsuhito", 
        "id": "sg:person.01112055511.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112055511.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Masayo", 
        "id": "sg:person.01253533533.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253533533.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morikawa", 
        "givenName": "Masayuki", 
        "id": "sg:person.0631347614.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631347614.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kobayashi", 
        "givenName": "Takanobu", 
        "id": "sg:person.01011650027.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011650027.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Chemistry, Graduate School of Engineering Science, Osaka University, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Division of Chemistry, Graduate School of Engineering Science, Osaka University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwai", 
        "givenName": "Shigenori", 
        "id": "sg:person.0727600052.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727600052.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyazawa", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01174211627.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174211627.72"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2015-11-01", 
    "datePublishedReg": "2015-11-01", 
    "description": "Introduction2,2,4-Triamino-5(2H)-oxazolone (Oz) in a DNA strand is an oxidation product of guanine and 8-oxo-7, 8-dihydroguanine, and such a lesion can cause G-to-C transversions. Previously, Fpg/Nei and Nth were shown to have incision activity on Oz.FindingsWe investigated the activities of chlorella virus pyrimidine dimer glycosylase (cvPDG) and Escherichia coli endonucleases IV (Nfo) and V (Nfi) on Oz. Although the three enzymes have different repair mechanisms from Fpg/Nei and Nth, they still had incision activity on Oz.ConclusionsGiven the incision activities of cvPDG, Nfo and Nfi on Oz in addition to Fpg/Nei and Nth, Oz is DNA damage that can be repaired by diverse enzymes.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s41021-015-0022-8", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5807905", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1037587", 
        "issn": [
          "1880-7046", 
          "1880-7062"
        ], 
        "name": "Genes and Environment", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "37"
      }
    ], 
    "keywords": [
      "incision activity", 
      "DNA damage", 
      "repair mechanisms", 
      "oxazolone", 
      "C transversion", 
      "lesions", 
      "activity", 
      "Fpg/Nei", 
      "oz", 
      "Escherichia coli endonuclease IV", 
      "ConclusionsGiven", 
      "FindingsWe", 
      "different repair mechanisms", 
      "enzyme", 
      "damage", 
      "pyrimidine dimer glycosylase", 
      "transversions", 
      "glycosylase", 
      "mechanism", 
      "guanine", 
      "NFI", 
      "addition", 
      "oxidation products", 
      "endonuclease IV", 
      "Nei", 
      "diverse enzymes", 
      "products", 
      "DNA strands", 
      "nth", 
      "strands", 
      "NFO", 
      "triamino"
    ], 
    "name": "Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and V have incision activity on 2,2,4-triamino-5(2H)-oxazolone", 
    "pagination": "22", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1051025308"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s41021-015-0022-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27350817"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s41021-015-0022-8", 
      "https://app.dimensions.ai/details/publication/pub.1051025308"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T10:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_684.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s41021-015-0022-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s41021-015-0022-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s41021-015-0022-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s41021-015-0022-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s41021-015-0022-8'


 

This table displays all metadata directly associated to this object as RDF triples.

134 TRIPLES      21 PREDICATES      58 URIs      50 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s41021-015-0022-8 schema:about anzsrc-for:06
2 anzsrc-for:0605
3 schema:author Nbef30c6243324fd494daacd33952b3cb
4 schema:datePublished 2015-11-01
5 schema:datePublishedReg 2015-11-01
6 schema:description Introduction2,2,4-Triamino-5(2H)-oxazolone (Oz) in a DNA strand is an oxidation product of guanine and 8-oxo-7, 8-dihydroguanine, and such a lesion can cause G-to-C transversions. Previously, Fpg/Nei and Nth were shown to have incision activity on Oz.FindingsWe investigated the activities of chlorella virus pyrimidine dimer glycosylase (cvPDG) and Escherichia coli endonucleases IV (Nfo) and V (Nfi) on Oz. Although the three enzymes have different repair mechanisms from Fpg/Nei and Nth, they still had incision activity on Oz.ConclusionsGiven the incision activities of cvPDG, Nfo and Nfi on Oz in addition to Fpg/Nei and Nth, Oz is DNA damage that can be repaired by diverse enzymes.
7 schema:genre article
8 schema:inLanguage en
9 schema:isAccessibleForFree true
10 schema:isPartOf N09c6fda5ea8947e78e5fb60a3bcf8e4f
11 N599ed025fca44506a39af480d058388b
12 sg:journal.1037587
13 schema:keywords C transversion
14 ConclusionsGiven
15 DNA damage
16 DNA strands
17 Escherichia coli endonuclease IV
18 FindingsWe
19 Fpg/Nei
20 NFI
21 NFO
22 Nei
23 activity
24 addition
25 damage
26 different repair mechanisms
27 diverse enzymes
28 endonuclease IV
29 enzyme
30 glycosylase
31 guanine
32 incision activity
33 lesions
34 mechanism
35 nth
36 oxazolone
37 oxidation products
38 oz
39 products
40 pyrimidine dimer glycosylase
41 repair mechanisms
42 strands
43 transversions
44 triamino
45 schema:name Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and V have incision activity on 2,2,4-triamino-5(2H)-oxazolone
46 schema:pagination 22
47 schema:productId N197168fcaceb4738a9ab7c7cfd6f6641
48 N1c2d233aae044a2eb941586b93025963
49 N2a63a4941ede48debd87b5ce95b1bdf8
50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051025308
51 https://doi.org/10.1186/s41021-015-0022-8
52 schema:sdDatePublished 2022-05-10T10:15
53 schema:sdLicense https://scigraph.springernature.com/explorer/license/
54 schema:sdPublisher Nce068135220c472d93c8c10534d88c8a
55 schema:url https://doi.org/10.1186/s41021-015-0022-8
56 sgo:license sg:explorer/license/
57 sgo:sdDataset articles
58 rdf:type schema:ScholarlyArticle
59 N09c6fda5ea8947e78e5fb60a3bcf8e4f schema:volumeNumber 37
60 rdf:type schema:PublicationVolume
61 N197168fcaceb4738a9ab7c7cfd6f6641 schema:name doi
62 schema:value 10.1186/s41021-015-0022-8
63 rdf:type schema:PropertyValue
64 N1c2d233aae044a2eb941586b93025963 schema:name dimensions_id
65 schema:value pub.1051025308
66 rdf:type schema:PropertyValue
67 N2a63a4941ede48debd87b5ce95b1bdf8 schema:name pubmed_id
68 schema:value 27350817
69 rdf:type schema:PropertyValue
70 N599ed025fca44506a39af480d058388b schema:issueNumber 1
71 rdf:type schema:PublicationIssue
72 N5e1a3d3e38dc4e8d9ddeb46cfbb46d48 rdf:first sg:person.0631347614.24
73 rdf:rest Nd7524f32cac74d7f960e901c0416c128
74 N8d228b3688de415b82eb01418c271eea rdf:first sg:person.01174211627.72
75 rdf:rest rdf:nil
76 Nb13b54bc60dc496cad375881d4677df8 rdf:first sg:person.01253533533.12
77 rdf:rest N5e1a3d3e38dc4e8d9ddeb46cfbb46d48
78 Nbef30c6243324fd494daacd33952b3cb rdf:first sg:person.01112055511.59
79 rdf:rest Nb13b54bc60dc496cad375881d4677df8
80 Nce068135220c472d93c8c10534d88c8a schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 Nd7524f32cac74d7f960e901c0416c128 rdf:first sg:person.01011650027.50
83 rdf:rest Ne92560e1ffa2450089d289acb72335bc
84 Ne92560e1ffa2450089d289acb72335bc rdf:first sg:person.0727600052.12
85 rdf:rest N8d228b3688de415b82eb01418c271eea
86 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
87 schema:name Biological Sciences
88 rdf:type schema:DefinedTerm
89 anzsrc-for:0605 schema:inDefinedTermSet anzsrc-for:
90 schema:name Microbiology
91 rdf:type schema:DefinedTerm
92 sg:grant.5807905 http://pending.schema.org/fundedItem sg:pub.10.1186/s41021-015-0022-8
93 rdf:type schema:MonetaryGrant
94 sg:journal.1037587 schema:issn 1880-7046
95 1880-7062
96 schema:name Genes and Environment
97 schema:publisher Springer Nature
98 rdf:type schema:Periodical
99 sg:person.01011650027.50 schema:affiliation grid-institutes:grid.412769.f
100 schema:familyName Kobayashi
101 schema:givenName Takanobu
102 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011650027.50
103 rdf:type schema:Person
104 sg:person.01112055511.59 schema:affiliation grid-institutes:grid.412769.f
105 schema:familyName Kino
106 schema:givenName Katsuhito
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112055511.59
108 rdf:type schema:Person
109 sg:person.01174211627.72 schema:affiliation grid-institutes:grid.412769.f
110 schema:familyName Miyazawa
111 schema:givenName Hiroshi
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174211627.72
113 rdf:type schema:Person
114 sg:person.01253533533.12 schema:affiliation grid-institutes:grid.412769.f
115 schema:familyName Suzuki
116 schema:givenName Masayo
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253533533.12
118 rdf:type schema:Person
119 sg:person.0631347614.24 schema:affiliation grid-institutes:grid.412769.f
120 schema:familyName Morikawa
121 schema:givenName Masayuki
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631347614.24
123 rdf:type schema:Person
124 sg:person.0727600052.12 schema:affiliation grid-institutes:grid.136593.b
125 schema:familyName Iwai
126 schema:givenName Shigenori
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727600052.12
128 rdf:type schema:Person
129 grid-institutes:grid.136593.b schema:alternateName Division of Chemistry, Graduate School of Engineering Science, Osaka University, Osaka, Japan
130 schema:name Division of Chemistry, Graduate School of Engineering Science, Osaka University, Osaka, Japan
131 rdf:type schema:Organization
132 grid-institutes:grid.412769.f schema:alternateName Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan
133 schema:name Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, 769-2193, Sanuki, Kagawa, Japan
134 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...