Patch-augmented rotator cuff surgery (PARCS) study—protocol for a feasibility study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Jonathan A. Cook, Naomi Merritt, Jonathan L. Rees, Joanna C. Crocker, Sally Hopewell, Melina Dritsaki, David J. Beard, Amar Rangan, Cushla Cooper, Lucksy Kottam, Dair Farrar-Hockley, Michael Thomas, Robert Earle, Andrew J. Carr

ABSTRACT

Background: A rotator cuff tear is a common disabling shoulder problem. Symptoms include pain, weakness, lack of shoulder mobility and sleep disturbance. Many patients require surgery to repair the tear; however, there is a high failure rate. There is a pressing need to improve the outcome of rotator cuff surgery and the use of patch augmentation to provide support to the healing process and improve patient outcomes holds new promise. Patches have been made using different materials (e.g. human/animal skin or intestine tissue, and completely synthetic materials) and processes (e.g. woven or a mesh). However, clinical evidence on their use is limited. The aim of the patch-augmented rotator cuff surgery (PARCS) feasibility study is to determine, using a mixed method approach, the design of a definitive randomised trial assessing the effectiveness and cost-effectiveness of a patch to augment surgical repair of the rotator cuff that is both acceptable to stakeholders and feasible. Methods: The objectives of this six-stage mixed methods feasibility study are to determine current practice, evidence and views about patch use; achieve consensus on the design of a randomised trial to evaluate patch-augmented rotator cuff surgery; and assess the acceptability and feasibility of the proposed design. The six stages will involve a systematic review of clinical evidence, two surveys of surgeons, focus groups and interviews with stakeholders, a Delphi study and a consensus meeting. The various stakeholders (including patients, surgeons, and representatives from industry, the NHS and regulatory bodies) will be involved across the six stages. Discussion: The PARCS feasibility study will inform the feasibility and acceptability of a randomised trial of the effectiveness and cost-effectiveness of a patch-augmented rotator cuff surgery. Consensus opinion on the basic design of a randomised trial will be sought. Trial registration: Not applicable. More... »

PAGES

188

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40814-018-0380-7

DOI

http://dx.doi.org/10.1186/s40814-018-0380-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110822141

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30598834


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