Ontology type: schema:ScholarlyArticle Open Access: True
2017-12
AUTHORSJuan Hernandez-Garcia, Nardy Robben, Damien Magnée, Thomas Eley, Ian Dennis, Sara M. Kayes, Jill R. Thomson, Alexander W. Tucker
ABSTRACTBACKGROUND: The usefulness of oral fluid (OF) sampling for surveillance of infections in pig populations is already accepted but its value as a tool to support investigations of porcine respiratory disease complex (PRDC) has been less well studied. This study set out to describe detection patterns of porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), swine influenza virus type A (SIV) and Mycoplasma hyopneumoniae (M. hyo) among farms showing differing severity of PRDC. The study included six wean-to-finish pig batches from farms with historical occurrence of respiratory disease. OF samples were collected from six pens every two weeks from the 5th to the 21st week of age and tested by real time PCR for presence of PRRSV, SIV and M. hyo and by quantitative real time PCR for PCV2. Data was evaluated alongside clinical and post-mortem observations, mortality rate, slaughter pathology, histopathology, and immunohistochemistry testing data for PCV2 antigen where available. RESULTS: PRRSV and M. hyo were detectable in OF but with inconsistency between pens at the same sampling time and within pens over sequential sampling times. Detection of SIV in clinical and subclinical cases showed good consistency between pens at the same sampling time point with detection possible for periods of 2-4 weeks. Quantitative testing of OF for PCV2 indicated different patterns and levels of detection between farms unaffected or affected by porcine circovirus diseases (PCVD). There was good correlation of PCR results for multiple samples collected from the same pen but no associations were found between prevalence of positive test results and pen location in the building or sex of pigs. CONCLUSIONS: Detection patterns for PRRSV, SIV and M. hyo supported the effectiveness of OF testing as an additional tool for diagnostic investigation of PRDC but emphasised the importance of sampling from multiple pens and on multiple occasions. Preliminary evidence supported the measurement of PCV2 load in pooled OF as a tool for prediction of clinical or subclinical PCVD at farm level. More... »
PAGES7
http://scigraph.springernature.com/pub.10.1186/s40813-017-0055-4
DOIhttp://dx.doi.org/10.1186/s40813-017-0055-4
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1083941663
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28405463
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Public Health and Health Services",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Cambridge",
"id": "https://www.grid.ac/institutes/grid.5335.0",
"name": [
"Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB30ES, Cambridge, England, UK"
],
"type": "Organization"
},
"familyName": "Hernandez-Garcia",
"givenName": "Juan",
"id": "sg:person.01200065077.53",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200065077.53"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Thermo Fisher Scientific (United States)",
"id": "https://www.grid.ac/institutes/grid.418190.5",
"name": [
"Thermo Fisher Scientific, Waltham, MA, USA"
],
"type": "Organization"
},
"familyName": "Robben",
"givenName": "Nardy",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Thermo Fisher Scientific (United States)",
"id": "https://www.grid.ac/institutes/grid.418190.5",
"name": [
"Thermo Fisher Scientific, Waltham, MA, USA"
],
"type": "Organization"
},
"familyName": "Magn\u00e9e",
"givenName": "Damien",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of London",
"id": "https://www.grid.ac/institutes/grid.4464.2",
"name": [
"Royal Veterinary College, University of London, London, England, UK"
],
"type": "Organization"
},
"familyName": "Eley",
"givenName": "Thomas",
"id": "sg:person.0741631247.51",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741631247.51"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"BQP Ltd., Stradbroke, England, UK"
],
"type": "Organization"
},
"familyName": "Dennis",
"givenName": "Ian",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Scotland's Rural College",
"id": "https://www.grid.ac/institutes/grid.426884.4",
"name": [
"SAC Consulting Veterinary, Scotland\u2019s Rural College (SRUC), Penicuik, Midlothian, Scotland, UK"
],
"type": "Organization"
},
"familyName": "Kayes",
"givenName": "Sara M.",
"id": "sg:person.01227462346.24",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227462346.24"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Scotland's Rural College",
"id": "https://www.grid.ac/institutes/grid.426884.4",
"name": [
"SAC Consulting Veterinary, Scotland\u2019s Rural College (SRUC), Penicuik, Midlothian, Scotland, UK"
],
"type": "Organization"
},
"familyName": "Thomson",
"givenName": "Jill R.",
"id": "sg:person.01121463235.33",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121463235.33"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Cambridge",
"id": "https://www.grid.ac/institutes/grid.5335.0",
"name": [
"Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB30ES, Cambridge, England, UK"
],
"type": "Organization"
},
"familyName": "Tucker",
"givenName": "Alexander W.",
"id": "sg:person.0656035655.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656035655.06"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1177/104063871102300207",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001667626"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063871102300207",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001667626"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1743-422x-10-265",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002081408",
"https://doi.org/10.1186/1743-422x-10-265"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2005.10.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003545587"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.prevetmed.2011.11.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003914948"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tvjl.2011.11.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004820415"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vaccine.2014.02.088",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006061241"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1101/gr.3.6.365",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006530648"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jviromet.2003.12.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006926536"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2008.10.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007024385"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2011.05.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008521441"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1746-6148-7-82",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015051862",
"https://doi.org/10.1186/1746-6148-7-82"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.virusres.2011.10.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016632431"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s1466252310000010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017991095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063870201400601",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018238904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063870201400601",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018238904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jveb.2015.01.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019057499"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063870802000203",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019847962"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063870802000203",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019847962"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.rvsc.2016.09.014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020705297"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2016.01.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024894277"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s1466252311000120",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027470857"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vaccine.2015.10.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029798516"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tvjl.2013.02.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032475725"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.virusres.2011.09.014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034016957"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1040638713481471",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034175845"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1040638713481471",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034175845"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1750-2659.2011.00276.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036191556"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063871102300208",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038322998"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/104063871102300208",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038322998"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1865-1682.2010.01189.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038578420"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1751-0147-52-22",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039997371",
"https://doi.org/10.1186/1751-0147-52-22"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0139586",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041452558"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2013.11.035",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049019218"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vetmic.2013.11.035",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049019218"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tvjl.2013.06.014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050712368"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.prevetmed.2010.09.022",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051552275"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jviromet.2013.12.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052830242"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0022172400041887",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054797990"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1051/vetres:2000122",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057071937"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/jvi.76.7.3232-3239.2002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062713237"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2460/javma.230.2.244",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070768930"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078049286",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4142/jvs.2017.18.3.283",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1079322040"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/9781555817947",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1109671947"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/9781555817947",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1109671947"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-12",
"datePublishedReg": "2017-12-01",
"description": "BACKGROUND: The usefulness of oral fluid (OF) sampling for surveillance of infections in pig populations is already accepted but its value as a tool to support investigations of porcine respiratory disease complex (PRDC) has been less well studied. This study set out to describe detection patterns of porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), swine influenza virus type A (SIV) and Mycoplasma hyopneumoniae (M. hyo) among farms showing differing severity of PRDC. The study included six wean-to-finish pig batches from farms with historical occurrence of respiratory disease. OF samples were collected from six pens every two weeks from the 5th to the 21st week of age and tested by real time PCR for presence of PRRSV, SIV and M. hyo and by quantitative real time PCR for PCV2. Data was evaluated alongside clinical and post-mortem observations, mortality rate, slaughter pathology, histopathology, and immunohistochemistry testing data for PCV2 antigen where available.\nRESULTS: PRRSV and M. hyo were detectable in OF but with inconsistency between pens at the same sampling time and within pens over sequential sampling times. Detection of SIV in clinical and subclinical cases showed good consistency between pens at the same sampling time point with detection possible for periods of 2-4 weeks. Quantitative testing of OF for PCV2 indicated different patterns and levels of detection between farms unaffected or affected by porcine circovirus diseases (PCVD). There was good correlation of PCR results for multiple samples collected from the same pen but no associations were found between prevalence of positive test results and pen location in the building or sex of pigs.\nCONCLUSIONS: Detection patterns for PRRSV, SIV and M. hyo supported the effectiveness of OF testing as an additional tool for diagnostic investigation of PRDC but emphasised the importance of sampling from multiple pens and on multiple occasions. Preliminary evidence supported the measurement of PCV2 load in pooled OF as a tool for prediction of clinical or subclinical PCVD at farm level.",
"genre": "research_article",
"id": "sg:pub.10.1186/s40813-017-0055-4",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1053686",
"issn": [
"2055-5660"
],
"name": "Porcine Health Management",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "3"
}
],
"name": "The use of oral fluids to monitor key pathogens in porcine respiratory disease complex",
"pagination": "7",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"3896880856118795dfdac83d4a4806889e3755f3b1f02f38f0096a40b814a7d1"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28405463"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101684126"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s40813-017-0055-4"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1083941663"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s40813-017-0055-4",
"https://app.dimensions.ai/details/publication/pub.1083941663"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T09:53",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89793_00000002.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1186%2Fs40813-017-0055-4"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40813-017-0055-4'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40813-017-0055-4'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40813-017-0055-4'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40813-017-0055-4'
This table displays all metadata directly associated to this object as RDF triples.
244 TRIPLES
21 PREDICATES
68 URIs
21 LITERALS
9 BLANK NODES