The dangers of mass drug administration of albendazole in Nepal, a Neurocysticercosis-endemic region View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-10-23

AUTHORS

Gaurav Nepal, Ghanshyam Kharel, Yow Ka Shing, Rajeev Ojha, Sujan Jamarkattel, Jayant Kumar Yadav, Himani Vyas, Dhiraj Poudyal, Ranjit Sah

ABSTRACT

The majority of cases of Neurocysticercosis (NCC) are asymptomatic. Injudicious use of antihelmintics like albendazole (ALB) can cause cyst degeneration and perilesional inflammation, thus rendering asymptomatic individuals symptomatic with seizures, headache, vascular events, or cerebral edema. Mass drug administration (MDA) using ALB is a very common practice in developing countries like Nepal to contain transmission of soil-transmitted helminths (STH) and lymphatic filariasis (LF). Although the benefits of ALB-based MDA in the general population cannot be undermined, there can be severe consequences in certain groups, especially those with latent NCC. In this commentary, we discuss the effect it may have on such patients, and suggest potential solutions. More... »

PAGES

22

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40794-020-00122-2

DOI

http://dx.doi.org/10.1186/s40794-020-00122-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1132012196

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33110612


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