Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Elena Curto, Astrid Crespo-Lessmann, María Victoria González-Gutiérrez, Santiago Bardagí, Concepción Cañete, Concha Pellicer, Teresa Bazús, María del Carmen Vennera, Carlos Martínez, Vicente Plaza

ABSTRACT

Background: The prevalence of chronic diseases in the elderly (> 65 years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65 years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com). Methods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged < 65 years (A), younger elderly aged 65-74 years (B) and older elderly aged ≥75 years (C). Results: Predominant features of elderly patients with asthma (N = 471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p < 0.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N = 398) were being treated with omalizumab and 8.2% (N = 140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%). Conclusions: Asthma in adults aged> 65 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients. More... »

PAGES

2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x

DOI

http://dx.doi.org/10.1186/s40733-019-0049-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112878655

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30937177


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Curto", 
        "givenName": "Elena", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Crespo-Lessmann", 
        "givenName": "Astrid", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Maresme Health Consortium", 
          "id": "https://www.grid.ac/institutes/grid.466613.0", 
          "name": [
            "Servicio de Neumolog\u00eda, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Matar\u00f3, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez-Guti\u00e9rrez", 
        "givenName": "Mar\u00eda Victoria", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Maresme Health Consortium", 
          "id": "https://www.grid.ac/institutes/grid.466613.0", 
          "name": [
            "Servicio de Neumolog\u00eda, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Matar\u00f3, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bardag\u00ed", 
        "givenName": "Santiago", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Servicio de Neumolog\u00eda, Hospital General de l\u2019Hospitalet, Av. Josep Molins 29, 08906 L\u2019Hospitalet de Llobregat, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ca\u00f1ete", 
        "givenName": "Concepci\u00f3n", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Comarcal Francesc De Borja, Avinguda de la Medicina 6, 46702 Gandia, Val\u00e8ncia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pellicer", 
        "givenName": "Concha", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University Hospital of Asturias", 
          "id": "https://www.grid.ac/institutes/grid.411052.3", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Universitario Central de Asturias, Av. Roma s/n, 3301, Oviedo, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baz\u00fas", 
        "givenName": "Teresa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Clinic of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.410458.c", 
          "name": [
            "Servici\u00f3 de Neumolog\u00eda, Hospital Clinic de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vennera", 
        "givenName": "Mar\u00eda del Carmen", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Germans Trias i Pujol", 
          "id": "https://www.grid.ac/institutes/grid.411438.b", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00ednez", 
        "givenName": "Carlos", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plaza", 
        "givenName": "Vicente", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1089/jamp.2015.1212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002210817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/jas-100000259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002399271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.orcp.2015.11.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009784142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2500/aap.2013.34.3692", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011381226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm/148.1.123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011938027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2015/692546", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013036935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02770900701752615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013132045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2007.06.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017853514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/cia.s94741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023302417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.116.3.603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025561837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.116.3.603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025561837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2013.01.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028933306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200406-710st", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029466875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000029465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029497040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10654-013-9800-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030011527", 
          "https://doi.org/10.1007/s10654-013-9800-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00365529309096078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030138310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.125.6.2046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033197864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4168/aair.2014.6.6.504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034377184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2006.11.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035828165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201410-1876pp", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036303583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/jas-100000023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036551098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1157/13090581", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038372564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.niox.2015.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039405144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arbres.2014.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041183149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1447-0594.2006.00341.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042357046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.161.4.9810093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042860796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1579-2129(06)60272-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045509782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0300-2896(09)73458-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046181464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ageing/32.1.43", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046800394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1939-4551-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046814620", 
          "https://doi.org/10.1186/1939-4551-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1939-4551-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046814620", 
          "https://doi.org/10.1186/1939-4551-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.00080312", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050761388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-4933-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050814888", 
          "https://doi.org/10.1186/1742-4933-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-4933-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050814888", 
          "https://doi.org/10.1186/1742-4933-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2011.06.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051764588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0030-1265897", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057229873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201211-2116oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063365498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081997634", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40266-017-0449-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084038555", 
          "https://doi.org/10.1007/s40266-017-0449-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40266-017-0449-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084038555", 
          "https://doi.org/10.1007/s40266-017-0449-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/all.13258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090779364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12931-017-0684-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099704467", 
          "https://doi.org/10.1186/s12931-017-0684-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Background: The prevalence of chronic diseases in the elderly (>\u200965\u2009years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65\u2009years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com).\nMethods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged <\u200965\u2009years (A), younger elderly aged 65-74\u2009years (B) and older elderly aged \u226575\u2009years (C).\nResults: Predominant features of elderly patients with asthma (N\u00a0=\u2009471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p\u00a0<\u20090.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N\u00a0=\u2009398) were being treated with omalizumab and 8.2% (N\u00a0=\u2009140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%).\nConclusions: Asthma in adults aged>\u200965 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s40733-019-0049-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1052614", 
        "issn": [
          "2054-7064"
        ], 
        "name": "Asthma Research and Practice", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "name": "Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older", 
    "pagination": "2", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s40733-019-0049-x"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ad60c149df2f99be9c536890c639289ea5c7e76aac7396b1f4adf249d4daa1e6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112878655"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101670236"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30937177"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s40733-019-0049-x", 
      "https://app.dimensions.ai/details/publication/pub.1112878655"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91453_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs40733-019-0049-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'


 

This table displays all metadata directly associated to this object as RDF triples.

261 TRIPLES      21 PREDICATES      69 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s40733-019-0049-x schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author Na44839e7b4004f50801ba19c3966ad4e
4 schema:citation sg:pub.10.1007/s10654-013-9800-4
5 sg:pub.10.1007/s40266-017-0449-7
6 sg:pub.10.1186/1742-4933-7-8
7 sg:pub.10.1186/1939-4551-7-8
8 sg:pub.10.1186/s12931-017-0684-9
9 https://app.dimensions.ai/details/publication/pub.1081997634
10 https://doi.org/10.1016/j.arbres.2014.12.007
11 https://doi.org/10.1016/j.jaci.2006.11.007
12 https://doi.org/10.1016/j.jaci.2011.06.048
13 https://doi.org/10.1016/j.jaci.2018.02.004
14 https://doi.org/10.1016/j.niox.2015.08.008
15 https://doi.org/10.1016/j.orcp.2015.11.006
16 https://doi.org/10.1016/j.rmed.2007.06.031
17 https://doi.org/10.1016/j.rmed.2013.01.018
18 https://doi.org/10.1016/s0300-2896(09)73458-1
19 https://doi.org/10.1016/s1579-2129(06)60272-3
20 https://doi.org/10.1055/s-0030-1265897
21 https://doi.org/10.1080/02770900701752615
22 https://doi.org/10.1081/jas-100000023
23 https://doi.org/10.1081/jas-100000259
24 https://doi.org/10.1089/jamp.2015.1212
25 https://doi.org/10.1093/ageing/32.1.43
26 https://doi.org/10.1111/all.13258
27 https://doi.org/10.1111/j.1447-0594.2006.00341.x
28 https://doi.org/10.1155/2015/692546
29 https://doi.org/10.1157/13090581
30 https://doi.org/10.1159/000029465
31 https://doi.org/10.1164/ajrccm.161.4.9810093
32 https://doi.org/10.1164/ajrccm/148.1.123
33 https://doi.org/10.1164/rccm.200406-710st
34 https://doi.org/10.1164/rccm.201211-2116oc
35 https://doi.org/10.1164/rccm.201410-1876pp
36 https://doi.org/10.1183/09031936.00080312
37 https://doi.org/10.1183/13993003.00766-2016
38 https://doi.org/10.1378/chest.116.3.603
39 https://doi.org/10.1378/chest.125.6.2046
40 https://doi.org/10.2147/cia.s94741
41 https://doi.org/10.2500/aap.2013.34.3692
42 https://doi.org/10.3109/00365529309096078
43 https://doi.org/10.4168/aair.2014.6.6.504
44 schema:datePublished 2019-12
45 schema:datePublishedReg 2019-12-01
46 schema:description Background: The prevalence of chronic diseases in the elderly (> 65 years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65 years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com). Methods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged < 65 years (A), younger elderly aged 65-74 years (B) and older elderly aged ≥75 years (C). Results: Predominant features of elderly patients with asthma (N = 471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p < 0.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N = 398) were being treated with omalizumab and 8.2% (N = 140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%). Conclusions: Asthma in adults aged> 65 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree true
50 schema:isPartOf Na286c602b1ea41319000404168382223
51 Ne7ade7447437445cbbcfd498aa36df80
52 sg:journal.1052614
53 schema:name Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older
54 schema:pagination 2
55 schema:productId N175ed870c67f487e90f8c429362766a8
56 N40a977d0abfd4f00b20d0f1f645b68d9
57 Nc26f782b8fa948dda9b3c44996e6b9bf
58 Ne596c1cd5adf43a8ab18e351b0da851c
59 Nf09df7544231405e974be3d429d28d37
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112878655
61 https://doi.org/10.1186/s40733-019-0049-x
62 schema:sdDatePublished 2019-04-15T09:02
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher Nc29bd879cc5844e0a2d410199d2ad600
65 schema:url https://link.springer.com/10.1186%2Fs40733-019-0049-x
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N0220e73bb50c4c87ac28b9209e4ed8cf rdf:first Nf31324be67fe45e08674870f6eb52a1b
70 rdf:rest N0cf5ee5952e2459a85629bf9a6fc898d
71 N0cf5ee5952e2459a85629bf9a6fc898d rdf:first Nbb0ee611da1b4095a7947dcb6a828d36
72 rdf:rest N928975cc36cd40148e73634109016d0d
73 N1094080208a24dd7a36c259c456085aa rdf:first Na56ea8cbca9a46579c7545d0983bf8ac
74 rdf:rest rdf:nil
75 N12cd0ad242104d37b0cd949335990f6c schema:name Servicio de Neumología, Hospital General de l’Hospitalet, Av. Josep Molins 29, 08906 L’Hospitalet de Llobregat, Barcelona, Spain
76 rdf:type schema:Organization
77 N175ed870c67f487e90f8c429362766a8 schema:name dimensions_id
78 schema:value pub.1112878655
79 rdf:type schema:PropertyValue
80 N3ef7a5f79c9f4d6087e9cb32ba6a7afd schema:affiliation https://www.grid.ac/institutes/grid.466613.0
81 schema:familyName González-Gutiérrez
82 schema:givenName María Victoria
83 rdf:type schema:Person
84 N40a977d0abfd4f00b20d0f1f645b68d9 schema:name pubmed_id
85 schema:value 30937177
86 rdf:type schema:PropertyValue
87 N67da8c1ddb774bd6b27355b8fac32745 schema:affiliation https://www.grid.ac/institutes/grid.413396.a
88 schema:familyName Crespo-Lessmann
89 schema:givenName Astrid
90 rdf:type schema:Person
91 N6e5acc9411e147e0a8cf9bb98405c5e0 schema:affiliation https://www.grid.ac/institutes/grid.410458.c
92 schema:familyName Vennera
93 schema:givenName María del Carmen
94 rdf:type schema:Person
95 N734c9d6a95a64d31b666656ed2300ee9 rdf:first Nd1f93301d8714dd8988b109d001803f3
96 rdf:rest Na05bcfd3cd574679987e14b3839792b4
97 N873864a585a848aab828f911b2f7f0d9 schema:affiliation Na3708791aacc47f5975336fcf8792cca
98 schema:familyName Pellicer
99 schema:givenName Concha
100 rdf:type schema:Person
101 N8f42273f560e4c34981d3af6e3b9ef81 schema:affiliation https://www.grid.ac/institutes/grid.413396.a
102 schema:familyName Curto
103 schema:givenName Elena
104 rdf:type schema:Person
105 N928975cc36cd40148e73634109016d0d rdf:first N873864a585a848aab828f911b2f7f0d9
106 rdf:rest N734c9d6a95a64d31b666656ed2300ee9
107 N9b32c70701d94cfcaa8165ca3ba519ae rdf:first N3ef7a5f79c9f4d6087e9cb32ba6a7afd
108 rdf:rest N0220e73bb50c4c87ac28b9209e4ed8cf
109 Na05bcfd3cd574679987e14b3839792b4 rdf:first N6e5acc9411e147e0a8cf9bb98405c5e0
110 rdf:rest Nc6a8590ef67146999eb98daa1a97ef09
111 Na286c602b1ea41319000404168382223 schema:volumeNumber 5
112 rdf:type schema:PublicationVolume
113 Na2a2a61e22e641db935ccfe79ce6eb07 rdf:first N67da8c1ddb774bd6b27355b8fac32745
114 rdf:rest N9b32c70701d94cfcaa8165ca3ba519ae
115 Na3708791aacc47f5975336fcf8792cca schema:name Servicio de Neumología, Hospital Comarcal Francesc De Borja, Avinguda de la Medicina 6, 46702 Gandia, València, Spain
116 rdf:type schema:Organization
117 Na44839e7b4004f50801ba19c3966ad4e rdf:first N8f42273f560e4c34981d3af6e3b9ef81
118 rdf:rest Na2a2a61e22e641db935ccfe79ce6eb07
119 Na56ea8cbca9a46579c7545d0983bf8ac schema:affiliation https://www.grid.ac/institutes/grid.413396.a
120 schema:familyName Plaza
121 schema:givenName Vicente
122 rdf:type schema:Person
123 Nb9c4d7eb6a3a47ac98ed78c792d79179 schema:affiliation https://www.grid.ac/institutes/grid.411438.b
124 schema:familyName Martínez
125 schema:givenName Carlos
126 rdf:type schema:Person
127 Nbb0ee611da1b4095a7947dcb6a828d36 schema:affiliation N12cd0ad242104d37b0cd949335990f6c
128 schema:familyName Cañete
129 schema:givenName Concepción
130 rdf:type schema:Person
131 Nc26f782b8fa948dda9b3c44996e6b9bf schema:name readcube_id
132 schema:value ad60c149df2f99be9c536890c639289ea5c7e76aac7396b1f4adf249d4daa1e6
133 rdf:type schema:PropertyValue
134 Nc29bd879cc5844e0a2d410199d2ad600 schema:name Springer Nature - SN SciGraph project
135 rdf:type schema:Organization
136 Nc6a8590ef67146999eb98daa1a97ef09 rdf:first Nb9c4d7eb6a3a47ac98ed78c792d79179
137 rdf:rest N1094080208a24dd7a36c259c456085aa
138 Nd1f93301d8714dd8988b109d001803f3 schema:affiliation https://www.grid.ac/institutes/grid.411052.3
139 schema:familyName Bazús
140 schema:givenName Teresa
141 rdf:type schema:Person
142 Ne596c1cd5adf43a8ab18e351b0da851c schema:name nlm_unique_id
143 schema:value 101670236
144 rdf:type schema:PropertyValue
145 Ne7ade7447437445cbbcfd498aa36df80 schema:issueNumber 1
146 rdf:type schema:PublicationIssue
147 Nf09df7544231405e974be3d429d28d37 schema:name doi
148 schema:value 10.1186/s40733-019-0049-x
149 rdf:type schema:PropertyValue
150 Nf31324be67fe45e08674870f6eb52a1b schema:affiliation https://www.grid.ac/institutes/grid.466613.0
151 schema:familyName Bardagí
152 schema:givenName Santiago
153 rdf:type schema:Person
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
158 schema:name Cardiorespiratory Medicine and Haematology
159 rdf:type schema:DefinedTerm
160 sg:journal.1052614 schema:issn 2054-7064
161 schema:name Asthma Research and Practice
162 rdf:type schema:Periodical
163 sg:pub.10.1007/s10654-013-9800-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030011527
164 https://doi.org/10.1007/s10654-013-9800-4
165 rdf:type schema:CreativeWork
166 sg:pub.10.1007/s40266-017-0449-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084038555
167 https://doi.org/10.1007/s40266-017-0449-7
168 rdf:type schema:CreativeWork
169 sg:pub.10.1186/1742-4933-7-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050814888
170 https://doi.org/10.1186/1742-4933-7-8
171 rdf:type schema:CreativeWork
172 sg:pub.10.1186/1939-4551-7-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046814620
173 https://doi.org/10.1186/1939-4551-7-8
174 rdf:type schema:CreativeWork
175 sg:pub.10.1186/s12931-017-0684-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099704467
176 https://doi.org/10.1186/s12931-017-0684-9
177 rdf:type schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1081997634 schema:CreativeWork
179 https://doi.org/10.1016/j.arbres.2014.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041183149
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/j.jaci.2006.11.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035828165
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.jaci.2011.06.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051764588
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/j.jaci.2018.02.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103155117
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/j.niox.2015.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039405144
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/j.orcp.2015.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009784142
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/j.rmed.2007.06.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017853514
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/j.rmed.2013.01.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028933306
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0300-2896(09)73458-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046181464
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/s1579-2129(06)60272-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045509782
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1055/s-0030-1265897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057229873
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1080/02770900701752615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013132045
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1081/jas-100000023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036551098
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1081/jas-100000259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002399271
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1089/jamp.2015.1212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002210817
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1093/ageing/32.1.43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046800394
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1111/all.13258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090779364
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1111/j.1447-0594.2006.00341.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042357046
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1155/2015/692546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013036935
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1157/13090581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038372564
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1159/000029465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029497040
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1164/ajrccm.161.4.9810093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042860796
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1164/ajrccm/148.1.123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011938027
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1164/rccm.200406-710st schema:sameAs https://app.dimensions.ai/details/publication/pub.1029466875
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1164/rccm.201211-2116oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1063365498
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1164/rccm.201410-1876pp schema:sameAs https://app.dimensions.ai/details/publication/pub.1036303583
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1183/09031936.00080312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050761388
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1183/13993003.00766-2016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025007614
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1378/chest.116.3.603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025561837
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1378/chest.125.6.2046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033197864
238 rdf:type schema:CreativeWork
239 https://doi.org/10.2147/cia.s94741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023302417
240 rdf:type schema:CreativeWork
241 https://doi.org/10.2500/aap.2013.34.3692 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011381226
242 rdf:type schema:CreativeWork
243 https://doi.org/10.3109/00365529309096078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030138310
244 rdf:type schema:CreativeWork
245 https://doi.org/10.4168/aair.2014.6.6.504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034377184
246 rdf:type schema:CreativeWork
247 https://www.grid.ac/institutes/grid.410458.c schema:alternateName Hospital Clinic of Barcelona
248 schema:name Servició de Neumología, Hospital Clinic de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain
249 rdf:type schema:Organization
250 https://www.grid.ac/institutes/grid.411052.3 schema:alternateName Central University Hospital of Asturias
251 schema:name Servicio de Neumología, Hospital Universitario Central de Asturias, Av. Roma s/n, 3301, Oviedo, Spain
252 rdf:type schema:Organization
253 https://www.grid.ac/institutes/grid.411438.b schema:alternateName Hospital Universitari Germans Trias i Pujol
254 schema:name Servicio de Neumología, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Barcelona, Spain
255 rdf:type schema:Organization
256 https://www.grid.ac/institutes/grid.413396.a schema:alternateName Hospital de Sant Pau
257 schema:name Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Institut d’Investigació Biomédica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain
258 rdf:type schema:Organization
259 https://www.grid.ac/institutes/grid.466613.0 schema:alternateName Maresme Health Consortium
260 schema:name Servicio de Neumología, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Mataró, Barcelona, Spain
261 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...