Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Elena Curto, Astrid Crespo-Lessmann, María Victoria González-Gutiérrez, Santiago Bardagí, Concepción Cañete, Concha Pellicer, Teresa Bazús, María del Carmen Vennera, Carlos Martínez, Vicente Plaza

ABSTRACT

Background: The prevalence of chronic diseases in the elderly (> 65 years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65 years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com). Methods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged < 65 years (A), younger elderly aged 65-74 years (B) and older elderly aged ≥75 years (C). Results: Predominant features of elderly patients with asthma (N = 471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p < 0.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N = 398) were being treated with omalizumab and 8.2% (N = 140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%). Conclusions: Asthma in adults aged> 65 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients. More... »

PAGES

2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x

DOI

http://dx.doi.org/10.1186/s40733-019-0049-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112878655

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30937177


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Curto", 
        "givenName": "Elena", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Crespo-Lessmann", 
        "givenName": "Astrid", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Maresme Health Consortium", 
          "id": "https://www.grid.ac/institutes/grid.466613.0", 
          "name": [
            "Servicio de Neumolog\u00eda, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Matar\u00f3, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez-Guti\u00e9rrez", 
        "givenName": "Mar\u00eda Victoria", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Maresme Health Consortium", 
          "id": "https://www.grid.ac/institutes/grid.466613.0", 
          "name": [
            "Servicio de Neumolog\u00eda, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Matar\u00f3, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bardag\u00ed", 
        "givenName": "Santiago", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Servicio de Neumolog\u00eda, Hospital General de l\u2019Hospitalet, Av. Josep Molins 29, 08906 L\u2019Hospitalet de Llobregat, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ca\u00f1ete", 
        "givenName": "Concepci\u00f3n", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Comarcal Francesc De Borja, Avinguda de la Medicina 6, 46702 Gandia, Val\u00e8ncia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pellicer", 
        "givenName": "Concha", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University Hospital of Asturias", 
          "id": "https://www.grid.ac/institutes/grid.411052.3", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Universitario Central de Asturias, Av. Roma s/n, 3301, Oviedo, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baz\u00fas", 
        "givenName": "Teresa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Clinic of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.410458.c", 
          "name": [
            "Servici\u00f3 de Neumolog\u00eda, Hospital Clinic de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vennera", 
        "givenName": "Mar\u00eda del Carmen", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Germans Trias i Pujol", 
          "id": "https://www.grid.ac/institutes/grid.411438.b", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00ednez", 
        "givenName": "Carlos", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Sant Pau", 
          "id": "https://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Servicio de Neumolog\u00eda, Hospital de la Santa Creu i Sant Pau, Institut d\u2019Investigaci\u00f3 Biom\u00e9dica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plaza", 
        "givenName": "Vicente", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1089/jamp.2015.1212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002210817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/jas-100000259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002399271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.orcp.2015.11.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009784142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2500/aap.2013.34.3692", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011381226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm/148.1.123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011938027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2015/692546", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013036935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02770900701752615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013132045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2007.06.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017853514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/cia.s94741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023302417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00766-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025007614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.116.3.603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025561837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.116.3.603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025561837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2013.01.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028933306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200406-710st", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029466875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000029465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029497040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10654-013-9800-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030011527", 
          "https://doi.org/10.1007/s10654-013-9800-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00365529309096078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030138310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.125.6.2046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033197864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4168/aair.2014.6.6.504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034377184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2006.11.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035828165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201410-1876pp", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036303583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1081/jas-100000023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036551098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1157/13090581", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038372564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.niox.2015.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039405144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arbres.2014.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041183149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1447-0594.2006.00341.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042357046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.161.4.9810093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042860796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1579-2129(06)60272-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045509782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0300-2896(09)73458-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046181464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ageing/32.1.43", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046800394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1939-4551-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046814620", 
          "https://doi.org/10.1186/1939-4551-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1939-4551-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046814620", 
          "https://doi.org/10.1186/1939-4551-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.00080312", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050761388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-4933-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050814888", 
          "https://doi.org/10.1186/1742-4933-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-4933-7-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050814888", 
          "https://doi.org/10.1186/1742-4933-7-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2011.06.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051764588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0030-1265897", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057229873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201211-2116oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063365498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081997634", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40266-017-0449-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084038555", 
          "https://doi.org/10.1007/s40266-017-0449-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40266-017-0449-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084038555", 
          "https://doi.org/10.1007/s40266-017-0449-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/all.13258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090779364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12931-017-0684-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099704467", 
          "https://doi.org/10.1186/s12931-017-0684-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2018.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103155117"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Background: The prevalence of chronic diseases in the elderly (>\u200965\u2009years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65\u2009years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com).\nMethods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged <\u200965\u2009years (A), younger elderly aged 65-74\u2009years (B) and older elderly aged \u226575\u2009years (C).\nResults: Predominant features of elderly patients with asthma (N\u00a0=\u2009471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p\u00a0<\u20090.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N\u00a0=\u2009398) were being treated with omalizumab and 8.2% (N\u00a0=\u2009140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%).\nConclusions: Asthma in adults aged>\u200965 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s40733-019-0049-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1052614", 
        "issn": [
          "2054-7064"
        ], 
        "name": "Asthma Research and Practice", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "name": "Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older", 
    "pagination": "2", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s40733-019-0049-x"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ad60c149df2f99be9c536890c639289ea5c7e76aac7396b1f4adf249d4daa1e6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112878655"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101670236"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30937177"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s40733-019-0049-x", 
      "https://app.dimensions.ai/details/publication/pub.1112878655"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91453_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs40733-019-0049-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40733-019-0049-x'


 

This table displays all metadata directly associated to this object as RDF triples.

261 TRIPLES      21 PREDICATES      69 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s40733-019-0049-x schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N2b209526ba4945619bb2e7e542cdec66
4 schema:citation sg:pub.10.1007/s10654-013-9800-4
5 sg:pub.10.1007/s40266-017-0449-7
6 sg:pub.10.1186/1742-4933-7-8
7 sg:pub.10.1186/1939-4551-7-8
8 sg:pub.10.1186/s12931-017-0684-9
9 https://app.dimensions.ai/details/publication/pub.1081997634
10 https://doi.org/10.1016/j.arbres.2014.12.007
11 https://doi.org/10.1016/j.jaci.2006.11.007
12 https://doi.org/10.1016/j.jaci.2011.06.048
13 https://doi.org/10.1016/j.jaci.2018.02.004
14 https://doi.org/10.1016/j.niox.2015.08.008
15 https://doi.org/10.1016/j.orcp.2015.11.006
16 https://doi.org/10.1016/j.rmed.2007.06.031
17 https://doi.org/10.1016/j.rmed.2013.01.018
18 https://doi.org/10.1016/s0300-2896(09)73458-1
19 https://doi.org/10.1016/s1579-2129(06)60272-3
20 https://doi.org/10.1055/s-0030-1265897
21 https://doi.org/10.1080/02770900701752615
22 https://doi.org/10.1081/jas-100000023
23 https://doi.org/10.1081/jas-100000259
24 https://doi.org/10.1089/jamp.2015.1212
25 https://doi.org/10.1093/ageing/32.1.43
26 https://doi.org/10.1111/all.13258
27 https://doi.org/10.1111/j.1447-0594.2006.00341.x
28 https://doi.org/10.1155/2015/692546
29 https://doi.org/10.1157/13090581
30 https://doi.org/10.1159/000029465
31 https://doi.org/10.1164/ajrccm.161.4.9810093
32 https://doi.org/10.1164/ajrccm/148.1.123
33 https://doi.org/10.1164/rccm.200406-710st
34 https://doi.org/10.1164/rccm.201211-2116oc
35 https://doi.org/10.1164/rccm.201410-1876pp
36 https://doi.org/10.1183/09031936.00080312
37 https://doi.org/10.1183/13993003.00766-2016
38 https://doi.org/10.1378/chest.116.3.603
39 https://doi.org/10.1378/chest.125.6.2046
40 https://doi.org/10.2147/cia.s94741
41 https://doi.org/10.2500/aap.2013.34.3692
42 https://doi.org/10.3109/00365529309096078
43 https://doi.org/10.4168/aair.2014.6.6.504
44 schema:datePublished 2019-12
45 schema:datePublishedReg 2019-12-01
46 schema:description Background: The prevalence of chronic diseases in the elderly (> 65 years), including asthma, is growing, yet information available on asthma in this population is scarce.Our objective is to determine the differential clinical and functional characteristics of the population > 65 years old with asthma included in the Integrated Research Programs of Asthma Databank of the Spanish Society of Pneumology and Thoracic Surgery (www.bancodatosasma.com). Methods: Retrospective comparative descriptive study of demographic, clinical and functional variables for 1713 patients with asthma categorized into 3 age groups as follows: adults aged < 65 years (A), younger elderly aged 65-74 years (B) and older elderly aged ≥75 years (C). Results: Predominant features of elderly patients with asthma (N = 471) were the female sex, fewer smokers, greater obesity, poorer lung function, and lower values of nitric oxide in exhaled air (p < 0.01). The most frequently associated comorbidity was gastroesophageal reflux. The highest doses of inhaled corticosteroids were by group A (60.8%). For the sample overall, 23.2% (N = 398) were being treated with omalizumab and 8.2% (N = 140) were corticosteroid-dependent (10.6% in group B). The highest percentage of patients receiving antileukotriene agents was in group B (42.9%). Conclusions: Asthma in adults aged> 65 is more severe and associated with greater comorbidity, which would indicate the need for a more integrated and multidimensional approach to asthma treatment for these patients.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree true
50 schema:isPartOf N05291fc239ca4978ac876be42bba1586
51 N5d0686977c294e4eb5a475d4f5ea7a6b
52 sg:journal.1052614
53 schema:name Is asthma in the elderly different? Functional and clinical characteristics of asthma in individuals aged 65 years and older
54 schema:pagination 2
55 schema:productId N226b22f21045456c918552c8fa66bb9c
56 N3fb2afd3c35e48f2846b219788b1b821
57 N6213a1918ac143259928a5424e731d5f
58 Nd3ccc5c1ed1d4c24903fe95a4670871a
59 Nfd56da6db0db4fe9bcff40cd0ee762a1
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112878655
61 https://doi.org/10.1186/s40733-019-0049-x
62 schema:sdDatePublished 2019-04-15T09:02
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N96989d8ce83b49d6bcd9d684536d2530
65 schema:url https://link.springer.com/10.1186%2Fs40733-019-0049-x
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N05291fc239ca4978ac876be42bba1586 schema:volumeNumber 5
70 rdf:type schema:PublicationVolume
71 N125cd6923a944dce876c93122d13bb6f schema:affiliation https://www.grid.ac/institutes/grid.466613.0
72 schema:familyName González-Gutiérrez
73 schema:givenName María Victoria
74 rdf:type schema:Person
75 N14a91077ab0b4d95bba459658529fefe schema:name Servicio de Neumología, Hospital General de l’Hospitalet, Av. Josep Molins 29, 08906 L’Hospitalet de Llobregat, Barcelona, Spain
76 rdf:type schema:Organization
77 N162daed321b349ddb54c4a80e817b573 rdf:first Naa59dda742134ae0a6e826229755366d
78 rdf:rest rdf:nil
79 N190e11c0acc742f899b9fd0ebe2f9b7f schema:affiliation https://www.grid.ac/institutes/grid.413396.a
80 schema:familyName Crespo-Lessmann
81 schema:givenName Astrid
82 rdf:type schema:Person
83 N2106c3fd549e49b893d2e401a62f8f08 schema:affiliation Ndc94c3c944f84b0ba15ef06f43bda721
84 schema:familyName Pellicer
85 schema:givenName Concha
86 rdf:type schema:Person
87 N226b22f21045456c918552c8fa66bb9c schema:name dimensions_id
88 schema:value pub.1112878655
89 rdf:type schema:PropertyValue
90 N23efc51e669c4236b6c9a4ec9e3b62f0 rdf:first Nefa0b6c604e843e89a993dcd688b6f37
91 rdf:rest N162daed321b349ddb54c4a80e817b573
92 N2b209526ba4945619bb2e7e542cdec66 rdf:first Na312a560b7884abdab47b5b6935ba2e9
93 rdf:rest N786154d71e7049ceb2c8287151d48b3b
94 N3abb075a2ec244f7a623a49e2de9c07c rdf:first Nb13b910f58874c40ab4a7b7bbfb271de
95 rdf:rest Nd1a6695626274295ac13a0147d9e5a8c
96 N3fb2afd3c35e48f2846b219788b1b821 schema:name readcube_id
97 schema:value ad60c149df2f99be9c536890c639289ea5c7e76aac7396b1f4adf249d4daa1e6
98 rdf:type schema:PropertyValue
99 N5d0686977c294e4eb5a475d4f5ea7a6b schema:issueNumber 1
100 rdf:type schema:PublicationIssue
101 N6213a1918ac143259928a5424e731d5f schema:name nlm_unique_id
102 schema:value 101670236
103 rdf:type schema:PropertyValue
104 N64fa815082ab44848da7b03d9d798eba rdf:first Nedfe8fe2a76d47cba36dec72951517b4
105 rdf:rest N3abb075a2ec244f7a623a49e2de9c07c
106 N786154d71e7049ceb2c8287151d48b3b rdf:first N190e11c0acc742f899b9fd0ebe2f9b7f
107 rdf:rest Nca6e29b032624ab8889018c34079c2f3
108 N7b9859dd40fd418698d919451a894d16 schema:affiliation https://www.grid.ac/institutes/grid.410458.c
109 schema:familyName Vennera
110 schema:givenName María del Carmen
111 rdf:type schema:Person
112 N96989d8ce83b49d6bcd9d684536d2530 schema:name Springer Nature - SN SciGraph project
113 rdf:type schema:Organization
114 Na312a560b7884abdab47b5b6935ba2e9 schema:affiliation https://www.grid.ac/institutes/grid.413396.a
115 schema:familyName Curto
116 schema:givenName Elena
117 rdf:type schema:Person
118 Naa59dda742134ae0a6e826229755366d schema:affiliation https://www.grid.ac/institutes/grid.413396.a
119 schema:familyName Plaza
120 schema:givenName Vicente
121 rdf:type schema:Person
122 Nb13b910f58874c40ab4a7b7bbfb271de schema:affiliation N14a91077ab0b4d95bba459658529fefe
123 schema:familyName Cañete
124 schema:givenName Concepción
125 rdf:type schema:Person
126 Nb2d95e3b3cab4b9ebfce2822b417376c rdf:first N7b9859dd40fd418698d919451a894d16
127 rdf:rest N23efc51e669c4236b6c9a4ec9e3b62f0
128 Nca6e29b032624ab8889018c34079c2f3 rdf:first N125cd6923a944dce876c93122d13bb6f
129 rdf:rest N64fa815082ab44848da7b03d9d798eba
130 Nd1a6695626274295ac13a0147d9e5a8c rdf:first N2106c3fd549e49b893d2e401a62f8f08
131 rdf:rest Nf485c76f4d9841a981600636c97210f2
132 Nd3ccc5c1ed1d4c24903fe95a4670871a schema:name pubmed_id
133 schema:value 30937177
134 rdf:type schema:PropertyValue
135 Ndc94c3c944f84b0ba15ef06f43bda721 schema:name Servicio de Neumología, Hospital Comarcal Francesc De Borja, Avinguda de la Medicina 6, 46702 Gandia, València, Spain
136 rdf:type schema:Organization
137 Ned4ba9f50b5c4948af617eb3dba465c4 schema:affiliation https://www.grid.ac/institutes/grid.411052.3
138 schema:familyName Bazús
139 schema:givenName Teresa
140 rdf:type schema:Person
141 Nedfe8fe2a76d47cba36dec72951517b4 schema:affiliation https://www.grid.ac/institutes/grid.466613.0
142 schema:familyName Bardagí
143 schema:givenName Santiago
144 rdf:type schema:Person
145 Nefa0b6c604e843e89a993dcd688b6f37 schema:affiliation https://www.grid.ac/institutes/grid.411438.b
146 schema:familyName Martínez
147 schema:givenName Carlos
148 rdf:type schema:Person
149 Nf485c76f4d9841a981600636c97210f2 rdf:first Ned4ba9f50b5c4948af617eb3dba465c4
150 rdf:rest Nb2d95e3b3cab4b9ebfce2822b417376c
151 Nfd56da6db0db4fe9bcff40cd0ee762a1 schema:name doi
152 schema:value 10.1186/s40733-019-0049-x
153 rdf:type schema:PropertyValue
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
158 schema:name Cardiorespiratory Medicine and Haematology
159 rdf:type schema:DefinedTerm
160 sg:journal.1052614 schema:issn 2054-7064
161 schema:name Asthma Research and Practice
162 rdf:type schema:Periodical
163 sg:pub.10.1007/s10654-013-9800-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030011527
164 https://doi.org/10.1007/s10654-013-9800-4
165 rdf:type schema:CreativeWork
166 sg:pub.10.1007/s40266-017-0449-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084038555
167 https://doi.org/10.1007/s40266-017-0449-7
168 rdf:type schema:CreativeWork
169 sg:pub.10.1186/1742-4933-7-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050814888
170 https://doi.org/10.1186/1742-4933-7-8
171 rdf:type schema:CreativeWork
172 sg:pub.10.1186/1939-4551-7-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046814620
173 https://doi.org/10.1186/1939-4551-7-8
174 rdf:type schema:CreativeWork
175 sg:pub.10.1186/s12931-017-0684-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099704467
176 https://doi.org/10.1186/s12931-017-0684-9
177 rdf:type schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1081997634 schema:CreativeWork
179 https://doi.org/10.1016/j.arbres.2014.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041183149
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/j.jaci.2006.11.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035828165
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.jaci.2011.06.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051764588
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/j.jaci.2018.02.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103155117
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/j.niox.2015.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039405144
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/j.orcp.2015.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009784142
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/j.rmed.2007.06.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017853514
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/j.rmed.2013.01.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028933306
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0300-2896(09)73458-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046181464
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/s1579-2129(06)60272-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045509782
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1055/s-0030-1265897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057229873
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1080/02770900701752615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013132045
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1081/jas-100000023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036551098
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1081/jas-100000259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002399271
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1089/jamp.2015.1212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002210817
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1093/ageing/32.1.43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046800394
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1111/all.13258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090779364
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1111/j.1447-0594.2006.00341.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042357046
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1155/2015/692546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013036935
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1157/13090581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038372564
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1159/000029465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029497040
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1164/ajrccm.161.4.9810093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042860796
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1164/ajrccm/148.1.123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011938027
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1164/rccm.200406-710st schema:sameAs https://app.dimensions.ai/details/publication/pub.1029466875
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1164/rccm.201211-2116oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1063365498
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1164/rccm.201410-1876pp schema:sameAs https://app.dimensions.ai/details/publication/pub.1036303583
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1183/09031936.00080312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050761388
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1183/13993003.00766-2016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025007614
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1378/chest.116.3.603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025561837
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1378/chest.125.6.2046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033197864
238 rdf:type schema:CreativeWork
239 https://doi.org/10.2147/cia.s94741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023302417
240 rdf:type schema:CreativeWork
241 https://doi.org/10.2500/aap.2013.34.3692 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011381226
242 rdf:type schema:CreativeWork
243 https://doi.org/10.3109/00365529309096078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030138310
244 rdf:type schema:CreativeWork
245 https://doi.org/10.4168/aair.2014.6.6.504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034377184
246 rdf:type schema:CreativeWork
247 https://www.grid.ac/institutes/grid.410458.c schema:alternateName Hospital Clinic of Barcelona
248 schema:name Servició de Neumología, Hospital Clinic de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain
249 rdf:type schema:Organization
250 https://www.grid.ac/institutes/grid.411052.3 schema:alternateName Central University Hospital of Asturias
251 schema:name Servicio de Neumología, Hospital Universitario Central de Asturias, Av. Roma s/n, 3301, Oviedo, Spain
252 rdf:type schema:Organization
253 https://www.grid.ac/institutes/grid.411438.b schema:alternateName Hospital Universitari Germans Trias i Pujol
254 schema:name Servicio de Neumología, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Barcelona, Spain
255 rdf:type schema:Organization
256 https://www.grid.ac/institutes/grid.413396.a schema:alternateName Hospital de Sant Pau
257 schema:name Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Institut d’Investigació Biomédica Sant Pau, Carrer Mas Casanovas 90, 08041, Barcelona, Spain
258 rdf:type schema:Organization
259 https://www.grid.ac/institutes/grid.466613.0 schema:alternateName Maresme Health Consortium
260 schema:name Servicio de Neumología, Consorci Sanitari del Maresme, Carrer de Cirera 230, 08304 Mataró, Barcelona, Spain
261 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...