Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Jianhua Wang, Liang Hu, Ce Shi, Hong Jiang

ABSTRACT

The inter-visit variation of measuring bulbar conjunctival microvasculature and microcirculation needs to be considered when the results from multiple visits are interpreted. This study examined the inter-visit variability of measuring conjunctival microvasculature and microcirculation in habitual contact lens (HCL) wearers and non-contact lens (NCL) wearers. Twenty-eight subjects were recruited including 13 HCL wearers (10 females and 3 males; mean age ± standard deviation, 25.8 ± 4.6 years) who had worn contact lenses on a daily basis for at least 3 years and 15 NCL wearers (10 females and 5 males, age 25.5 ± 4.0 years) were recruited. The temporal bulbar conjunctiva was imaged using a functional slit-lamp bio-microscope (FSLB) imaging system. FSLB imaging was performed in the morning when the HCL wearers did not wear their lenses. The measurements included conjunctival vessel diameter, vessel density, blood flow velocity and flow volume. In addition, conjunctival microvasculature was analyzed using monofractal (Dbox, representing vessel density) and multifractal (D0 representing vessel complexity) analyses. The repeated measurement was conducted at least one week after the first visit and both eyes of each participant were imaged. The coefficient of variation (CV) was calculated as the standard deviation of the differences between test and re-test then divided by the mean of the measurements. The intra-class correlation coefficient (ICC) was also calculated. No significant differences of all vascular measurements in both the right and left eyes were found between two groups (P > 0.05). Between two measurements on two different visits, the CV was from 2.4% (vessel density D0) to 63.5% (blood flow volume Q) in HCL wearers and from 3.4% (D0) to 40.6% (blood flow volume) in NCL wearers. The ICC was from 0.60 (vessel diameter) to 0.81 (axial blood flow velocity VA) in HCL wearers and from 0.44 (Q) to 0.68 (cross-sectional blood flow velocity VS) in NCL wearers. The measurement variability of the vessel density of the bulbar conjunctiva appeared to have the smallest inter-visit variation. The measurement variability of the vasculature and circulation in HCL wearers were similar to that in NCL wearers. More... »

PAGES

10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40662-019-0135-4

DOI

http://dx.doi.org/10.1186/s40662-019-0135-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113161242


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Miami", 
          "id": "https://www.grid.ac/institutes/grid.26790.3a", 
          "name": [
            "Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Jianhua", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wenzhou Medical College", 
          "id": "https://www.grid.ac/institutes/grid.268099.c", 
          "name": [
            "Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA", 
            "School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Liang", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wenzhou Medical College", 
          "id": "https://www.grid.ac/institutes/grid.268099.c", 
          "name": [
            "Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA", 
            "School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shi", 
        "givenName": "Ce", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Miami", 
          "id": "https://www.grid.ac/institutes/grid.26790.3a", 
          "name": [
            "Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jiang", 
        "givenName": "Hong", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/eye.2015.250", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006920145", 
          "https://doi.org/10.1038/eye.2015.250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.13-13187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009013187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2015.05.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012998398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/icl.0000000000000241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013085640"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/icl.0000000000000241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013085640"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clae.2013.02.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015619559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0b013e3181f6f97d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018924342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0b013e3181f6f97d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018924342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/eye.2011.288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020158017", 
          "https://doi.org/10.1038/eye.2011.288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0000000000000968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020820964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0000000000000968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020820964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0000000000000968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020820964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.eye.6702295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021292267", 
          "https://doi.org/10.1038/sj.eye.6702295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.eye.6702295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021292267", 
          "https://doi.org/10.1038/sj.eye.6702295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2009.12.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025364843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2012.11.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025376586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bjo.2006.112680", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025872934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0b013e3180485d5f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026795863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0b013e3180485d5f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026795863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/opx.0b013e3180485d5f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026795863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2010.05.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027010739"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2013.06.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028115337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00140068-200301001-00042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029235089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00140068-200301001-00042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029235089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.07-1306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030133092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-199609000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032718077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-199609000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032718077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mvr.2014.01.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033592092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajo.2016.08.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040916298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1444-0938.2006.00069.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042842925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.exer.2016.06.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043040066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-200103000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043223788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-200103000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043223788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clae.2006.12.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045143254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10439-016-1568-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045495578", 
          "https://doi.org/10.1007/s10439-016-1568-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-198704000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046732695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006324-198704000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046732695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ophtha.2008.04.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052153434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d7d917", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d7d917", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d7d917", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3928/23258160-20121221-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071729764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077631749", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3233/ch-2011-1513", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078500376"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep45916", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084538104", 
          "https://doi.org/10.1038/srep45916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/icl.0000000000000389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084848804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/icl.0000000000000389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084848804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/icl.0000000000000389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084848804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clae.2017.12.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099620765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.18-24216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106103109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.18-24216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106103109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.18-24216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106103109"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "The inter-visit variation of measuring bulbar conjunctival microvasculature and microcirculation needs to be considered when the results from multiple visits are interpreted. This study examined the inter-visit variability of measuring conjunctival microvasculature and microcirculation in habitual contact lens (HCL) wearers and non-contact lens (NCL) wearers. Twenty-eight subjects were recruited including 13 HCL wearers (10 females and 3 males; mean age \u00b1 standard deviation, 25.8 \u00b1 4.6 years) who had worn contact lenses on a daily basis for at least 3 years and 15 NCL wearers (10 females and 5 males, age 25.5 \u00b1 4.0 years) were recruited. The temporal bulbar conjunctiva was imaged using a functional slit-lamp bio-microscope (FSLB) imaging system. FSLB imaging was performed in the morning when the HCL wearers did not wear their lenses. The measurements included conjunctival vessel diameter, vessel density, blood flow velocity and flow volume. In addition, conjunctival microvasculature was analyzed using monofractal (Dbox, representing vessel density) and multifractal (D0 representing vessel complexity) analyses. The repeated measurement was conducted at least one week after the first visit and both eyes of each participant were imaged. The coefficient of variation (CV) was calculated as the standard deviation of the differences between test and re-test then divided by the mean of the measurements. The intra-class correlation coefficient (ICC) was also calculated. No significant differences of all vascular measurements in both the right and left eyes were found between two groups (P > 0.05). Between two measurements on two different visits, the CV was from 2.4% (vessel density D0) to 63.5% (blood flow volume Q) in HCL wearers and from 3.4% (D0) to 40.6% (blood flow volume) in NCL wearers. The ICC was from 0.60 (vessel diameter) to 0.81 (axial blood flow velocity VA) in HCL wearers and from 0.44 (Q) to 0.68 (cross-sectional blood flow velocity VS) in NCL wearers. The measurement variability of the vessel density of the bulbar conjunctiva appeared to have the smallest inter-visit variation. The measurement variability of the vasculature and circulation in HCL wearers were similar to that in NCL wearers.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s40662-019-0135-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1052268", 
        "issn": [
          "2326-0246", 
          "2326-0254"
        ], 
        "name": "Eye and Vision", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers", 
    "pagination": "10", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "cc5fc5d369c085e22432b4399b934f48ef568b9f4e621b4588b9af47fbfbe4ac"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s40662-019-0135-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113161242"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s40662-019-0135-4", 
      "https://app.dimensions.ai/details/publication/pub.1113161242"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000370_0000000370/records_46779_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs40662-019-0135-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40662-019-0135-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40662-019-0135-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40662-019-0135-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40662-019-0135-4'


 

This table displays all metadata directly associated to this object as RDF triples.

191 TRIPLES      21 PREDICATES      62 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s40662-019-0135-4 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N192d87bc3d91437b8904bfe2bce3083c
4 schema:citation sg:pub.10.1007/s10439-016-1568-8
5 sg:pub.10.1038/eye.2011.288
6 sg:pub.10.1038/eye.2015.250
7 sg:pub.10.1038/sj.eye.6702295
8 sg:pub.10.1038/srep45916
9 https://app.dimensions.ai/details/publication/pub.1077631749
10 https://doi.org/10.1016/j.ajo.2016.08.009
11 https://doi.org/10.1016/j.clae.2006.12.003
12 https://doi.org/10.1016/j.clae.2013.02.013
13 https://doi.org/10.1016/j.clae.2017.12.010
14 https://doi.org/10.1016/j.exer.2016.06.008
15 https://doi.org/10.1016/j.mvr.2009.12.003
16 https://doi.org/10.1016/j.mvr.2010.05.001
17 https://doi.org/10.1016/j.mvr.2012.11.003
18 https://doi.org/10.1016/j.mvr.2013.06.008
19 https://doi.org/10.1016/j.mvr.2014.01.005
20 https://doi.org/10.1016/j.mvr.2015.05.003
21 https://doi.org/10.1016/j.ophtha.2008.04.002
22 https://doi.org/10.1097/00006324-198704000-00003
23 https://doi.org/10.1097/00006324-199609000-00006
24 https://doi.org/10.1097/00006324-200103000-00006
25 https://doi.org/10.1097/00140068-200301001-00042
26 https://doi.org/10.1097/icl.0000000000000241
27 https://doi.org/10.1097/icl.0000000000000389
28 https://doi.org/10.1097/opx.0000000000000968
29 https://doi.org/10.1097/opx.0b013e3180485d5f
30 https://doi.org/10.1097/opx.0b013e3181f6f97d
31 https://doi.org/10.1111/j.1444-0938.2006.00069.x
32 https://doi.org/10.1136/bjo.2006.112680
33 https://doi.org/10.1167/iovs.07-1306
34 https://doi.org/10.1167/iovs.13-13187
35 https://doi.org/10.1167/iovs.18-24216
36 https://doi.org/10.1212/wnl.0b013e3181d7d917
37 https://doi.org/10.3233/ch-2011-1513
38 https://doi.org/10.3928/23258160-20121221-13
39 schema:datePublished 2019-12
40 schema:datePublishedReg 2019-12-01
41 schema:description The inter-visit variation of measuring bulbar conjunctival microvasculature and microcirculation needs to be considered when the results from multiple visits are interpreted. This study examined the inter-visit variability of measuring conjunctival microvasculature and microcirculation in habitual contact lens (HCL) wearers and non-contact lens (NCL) wearers. Twenty-eight subjects were recruited including 13 HCL wearers (10 females and 3 males; mean age ± standard deviation, 25.8 ± 4.6 years) who had worn contact lenses on a daily basis for at least 3 years and 15 NCL wearers (10 females and 5 males, age 25.5 ± 4.0 years) were recruited. The temporal bulbar conjunctiva was imaged using a functional slit-lamp bio-microscope (FSLB) imaging system. FSLB imaging was performed in the morning when the HCL wearers did not wear their lenses. The measurements included conjunctival vessel diameter, vessel density, blood flow velocity and flow volume. In addition, conjunctival microvasculature was analyzed using monofractal (Dbox, representing vessel density) and multifractal (D0 representing vessel complexity) analyses. The repeated measurement was conducted at least one week after the first visit and both eyes of each participant were imaged. The coefficient of variation (CV) was calculated as the standard deviation of the differences between test and re-test then divided by the mean of the measurements. The intra-class correlation coefficient (ICC) was also calculated. No significant differences of all vascular measurements in both the right and left eyes were found between two groups (P > 0.05). Between two measurements on two different visits, the CV was from 2.4% (vessel density D0) to 63.5% (blood flow volume Q) in HCL wearers and from 3.4% (D0) to 40.6% (blood flow volume) in NCL wearers. The ICC was from 0.60 (vessel diameter) to 0.81 (axial blood flow velocity VA) in HCL wearers and from 0.44 (Q) to 0.68 (cross-sectional blood flow velocity VS) in NCL wearers. The measurement variability of the vessel density of the bulbar conjunctiva appeared to have the smallest inter-visit variation. The measurement variability of the vasculature and circulation in HCL wearers were similar to that in NCL wearers.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree true
45 schema:isPartOf N65f800765acb4a0db7d513d53ac725d6
46 Ne695e10d9c89426ea10c51ab64a2c0d7
47 sg:journal.1052268
48 schema:name Inter-visit measurement variability of conjunctival vasculature and circulation in habitual contact lens wearers and non-lens wearers
49 schema:pagination 10
50 schema:productId N62afdc24d33f45ee8edb5dd3c3d64874
51 N9c100349191a40a2b4857ac8ae04b248
52 Nf23aca701b144c068b86b91132d32930
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113161242
54 https://doi.org/10.1186/s40662-019-0135-4
55 schema:sdDatePublished 2019-04-11T13:37
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher N096e759667f14d22b26e285033049dbf
58 schema:url https://link.springer.com/10.1186%2Fs40662-019-0135-4
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N096e759667f14d22b26e285033049dbf schema:name Springer Nature - SN SciGraph project
63 rdf:type schema:Organization
64 N192d87bc3d91437b8904bfe2bce3083c rdf:first Nfeaec25c854e4e508433bb2dd91633b8
65 rdf:rest Na266b55590ed41ea8037ffa9cadc168a
66 N375e9ff78d6d405a833d4d04fa325c95 rdf:first Nf0e6cbe82bf64122b2caaf346c44fdb8
67 rdf:rest N8cb8660fa2124e0ba69221a828495bdb
68 N62afdc24d33f45ee8edb5dd3c3d64874 schema:name doi
69 schema:value 10.1186/s40662-019-0135-4
70 rdf:type schema:PropertyValue
71 N65f800765acb4a0db7d513d53ac725d6 schema:volumeNumber 6
72 rdf:type schema:PublicationVolume
73 N7d7a8061310847a29001c6a9ad7925fe schema:affiliation https://www.grid.ac/institutes/grid.268099.c
74 schema:familyName Hu
75 schema:givenName Liang
76 rdf:type schema:Person
77 N8cb8660fa2124e0ba69221a828495bdb rdf:first Nf8ce92ecad1b4d398c130db3da561ed9
78 rdf:rest rdf:nil
79 N9c100349191a40a2b4857ac8ae04b248 schema:name dimensions_id
80 schema:value pub.1113161242
81 rdf:type schema:PropertyValue
82 Na266b55590ed41ea8037ffa9cadc168a rdf:first N7d7a8061310847a29001c6a9ad7925fe
83 rdf:rest N375e9ff78d6d405a833d4d04fa325c95
84 Ne695e10d9c89426ea10c51ab64a2c0d7 schema:issueNumber 1
85 rdf:type schema:PublicationIssue
86 Nf0e6cbe82bf64122b2caaf346c44fdb8 schema:affiliation https://www.grid.ac/institutes/grid.268099.c
87 schema:familyName Shi
88 schema:givenName Ce
89 rdf:type schema:Person
90 Nf23aca701b144c068b86b91132d32930 schema:name readcube_id
91 schema:value cc5fc5d369c085e22432b4399b934f48ef568b9f4e621b4588b9af47fbfbe4ac
92 rdf:type schema:PropertyValue
93 Nf8ce92ecad1b4d398c130db3da561ed9 schema:affiliation https://www.grid.ac/institutes/grid.26790.3a
94 schema:familyName Jiang
95 schema:givenName Hong
96 rdf:type schema:Person
97 Nfeaec25c854e4e508433bb2dd91633b8 schema:affiliation https://www.grid.ac/institutes/grid.26790.3a
98 schema:familyName Wang
99 schema:givenName Jianhua
100 rdf:type schema:Person
101 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
102 schema:name Medical and Health Sciences
103 rdf:type schema:DefinedTerm
104 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
105 schema:name Cardiorespiratory Medicine and Haematology
106 rdf:type schema:DefinedTerm
107 sg:journal.1052268 schema:issn 2326-0246
108 2326-0254
109 schema:name Eye and Vision
110 rdf:type schema:Periodical
111 sg:pub.10.1007/s10439-016-1568-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045495578
112 https://doi.org/10.1007/s10439-016-1568-8
113 rdf:type schema:CreativeWork
114 sg:pub.10.1038/eye.2011.288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020158017
115 https://doi.org/10.1038/eye.2011.288
116 rdf:type schema:CreativeWork
117 sg:pub.10.1038/eye.2015.250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006920145
118 https://doi.org/10.1038/eye.2015.250
119 rdf:type schema:CreativeWork
120 sg:pub.10.1038/sj.eye.6702295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021292267
121 https://doi.org/10.1038/sj.eye.6702295
122 rdf:type schema:CreativeWork
123 sg:pub.10.1038/srep45916 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084538104
124 https://doi.org/10.1038/srep45916
125 rdf:type schema:CreativeWork
126 https://app.dimensions.ai/details/publication/pub.1077631749 schema:CreativeWork
127 https://doi.org/10.1016/j.ajo.2016.08.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040916298
128 rdf:type schema:CreativeWork
129 https://doi.org/10.1016/j.clae.2006.12.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045143254
130 rdf:type schema:CreativeWork
131 https://doi.org/10.1016/j.clae.2013.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015619559
132 rdf:type schema:CreativeWork
133 https://doi.org/10.1016/j.clae.2017.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099620765
134 rdf:type schema:CreativeWork
135 https://doi.org/10.1016/j.exer.2016.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043040066
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1016/j.mvr.2009.12.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025364843
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1016/j.mvr.2010.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027010739
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1016/j.mvr.2012.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025376586
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1016/j.mvr.2013.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028115337
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1016/j.mvr.2014.01.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033592092
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1016/j.mvr.2015.05.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012998398
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1016/j.ophtha.2008.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052153434
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1097/00006324-198704000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046732695
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1097/00006324-199609000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032718077
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1097/00006324-200103000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043223788
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1097/00140068-200301001-00042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029235089
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1097/icl.0000000000000241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013085640
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1097/icl.0000000000000389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084848804
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1097/opx.0000000000000968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020820964
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1097/opx.0b013e3180485d5f schema:sameAs https://app.dimensions.ai/details/publication/pub.1026795863
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1097/opx.0b013e3181f6f97d schema:sameAs https://app.dimensions.ai/details/publication/pub.1018924342
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1111/j.1444-0938.2006.00069.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042842925
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1136/bjo.2006.112680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025872934
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1167/iovs.07-1306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030133092
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1167/iovs.13-13187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009013187
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1167/iovs.18-24216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106103109
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1212/wnl.0b013e3181d7d917 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064355165
180 rdf:type schema:CreativeWork
181 https://doi.org/10.3233/ch-2011-1513 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078500376
182 rdf:type schema:CreativeWork
183 https://doi.org/10.3928/23258160-20121221-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071729764
184 rdf:type schema:CreativeWork
185 https://www.grid.ac/institutes/grid.26790.3a schema:alternateName University of Miami
186 schema:name Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA
187 rdf:type schema:Organization
188 https://www.grid.ac/institutes/grid.268099.c schema:alternateName Wenzhou Medical College
189 schema:name Miller School of Medicine, Bascom Palmer Eye Institute, University of Miami, 1638 NW 10th Avenue, McKnight Building - Room 202A, 33136, Miami, FL, USA
190 School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China
191 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...