Optical coherence tomography angiography for the anterior segment View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Wen Di Lee, Kavya Devarajan, Jacqueline Chua, Leopold Schmetterer, Jodhbir S. Mehta, Marcus Ang

ABSTRACT

Optical coherence tomography angiography (OCTA) is a rapid and non-invasive technique for imaging vasculature in the eye. As OCTA can produce high-resolution cross-sectional images and allow depth-resolved analysis for accurate localization of pathology of interest, it has become a promising method for anterior segment imaging. Furthermore, OCTA offers a more patient-friendly alternative to the conventional invasive dye-based fluorescent angiography. However, conventional OCTA systems are typically designed and optimized for the posterior segment of the eye, and thus using OCTA for anterior segment imaging can present several difficulties and limitations. In this review, we summarized the recent developments and clinical applications in anterior segment OCTA (AS-OCTA) imaging, such as for the cornea, iris, sclera and conjunctiva. We also compared commercially available OCTA systems, discussed the limitations of adapting current OCTA technology for the anterior segment imaging, and proposed possible future directions for AS-OCTA systems. AS-OCTA provides potential for future clinical applications such as diagnosis of corneal and iris pathologies, pre-operative surgical planning, assessment of new anti-angiogenic therapeutics or evaluation of limbal stem cell deficiency. With further development, OCTA for anterior segment imaging in the clinics may become common in the near future. More... »

PAGES

4

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40662-019-0129-2

DOI

http://dx.doi.org/10.1186/s40662-019-0129-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111825244

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30775387


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