Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Reza Goharani, Amir Vahedian-Azimi, Behrooz Farzanegan, Farshid R. Bashar, Mohammadreza Hajiesmaeili, Seyedpouzhia Shojaei, Seyed J. Madani, Keivan Gohari-Moghaddam, Sevak Hatamian, Seyed M. M. Mosavinasab, Masoum Khoshfetrat, Mohammad A. Khabiri Khatir, Andrew C. Miller, for the MORZAK Collaborative

ABSTRACT

Objective: To determine if real-time compression feedback using a non-automated hand-held device improves patient outcomes from in-hospital cardiac arrest (IHCA). Methods: We conducted a prospective, randomized, controlled, parallel study (no crossover) of patients with IHCA in the mixed medical-surgical intensive care units (ICUs) of eight academic hospitals. Patients received either standard manual chest compressions or compressions performed with real-time feedback using the Cardio First Angel™ (CFA) device. The primary outcome was sustained return of spontaneous circulation (ROSC), and secondary outcomes were survival to ICU and hospital discharge. Results: One thousand four hundred fifty-four subjects were randomized; 900 were included. Sustained ROSC was significantly improved in the CFA group (66.7% vs. 42.4%, P < 0.001), as was survival to ICU discharge (59.8% vs. 33.6%) and survival to hospital discharge (54% vs. 28.4%, P < 0.001). Outcomes were not affected by intra-group comparisons based on intubation status. ROSC, survival to ICU, and hospital discharge were noted to be improved in inter-group comparisons of non-intubated patients, but not intubated ones. Conclusion: Use of the CFA compression feedback device improved event survival and survival to ICU and hospital discharge. Trial registration: The study was registered with Clinicaltrials.gov (NCT02845011), registered retrospectively on July 21, 2016. More... »

PAGES

5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40560-019-0357-5

DOI

http://dx.doi.org/10.1186/s40560-019-0357-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111611686

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30693086


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