Composition and biological activities of the aqueous extracts of three scleractinian corals from the Mexican Caribbean: Pseudodiploria strigosa, Porites astreoides ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-11-24

AUTHORS

Alejandro García-Arredondo, Alejandra Rojas-Molina, César Ibarra-Alvarado, Fernando Lazcano-Pérez, Roberto Arreguín-Espinosa, Judith Sánchez-Rodríguez

ABSTRACT

BackgroundScleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea, three scleractinian corals from the Mexican Caribbean, have been assessed for the first time.MethodsToxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the nociceptive activity was evaluated by the formalin test. The presence of phospholipases A2 (PLA2), serine proteases, and hyaluronidases was determined by enzymatic methods. Low-molecular-weight fractions were obtained by gel filtration chromatography and ultrafiltration.ResultsExtracts from the three species were toxic to crickets, induced hemolysis in human and rat erythrocytes, produced vasoconstriction on isolated rat aortic rings, and presented phospholipase A2 and serine-protease activity. Despite the fact that these corals are not considered to be harmless to humans, the extracts generated significant nociceptive responses. The matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of the low-molecular-weight fractions revealed the presence of peptides within a mass range of 3000 to 6000 Da. These fractions were toxic to crickets and two of them induced a transitory vasoconstrictor effect on isolated rat aortic rings.ConclusionThis study suggests that scleractinian corals produce low-molecular-weight peptides that are lethal to crickets and induce vasoconstriction. More... »

PAGES

32

References to SciGraph publications

  • 2013-12-29. Improved Insecticidal Toxicity by Fusing Cry1Ac of Bacillus thuringiensis with Av3 of Anemonia viridis in CURRENT MICROBIOLOGY
  • 2015-06-17. Pharmacological characterization of venoms from three theraphosid spiders: Poecilotheria regalis, Ceratogyrus darlingi and Brachypelma epicureanum in JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
  • 2009-11-30. Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts in BMC GENOMICS
  • 2014-11-12. Characteristics of hemolytic activity induced by the aqueous extract of the Mexican fire coral Millepora complanata in JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
  • 2006-01-01. Peptide Toxins in Sea Anemones: Structural and Functional Aspects in MARINE BIOTECHNOLOGY
  • 2015-10-13. Gene duplications are extensive and contribute significantly to the toxic proteome of nematocysts isolated from Acropora digitifera (Cnidaria: Anthozoa: Scleractinia) in BMC GENOMICS
  • 2015-10-22. Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology in JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
  • 1970-08. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 in NATURE
  • 2009-07-01. Transcriptome analysis of the venom gland of the scorpion Scorpiops jendeki: implication for the evolution of the scorpion venom arsenal in BMC GENOMICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s40409-016-0087-2

    DOI

    http://dx.doi.org/10.1186/s40409-016-0087-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034579061

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27904505


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0602", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Ecology", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.412861.8", 
              "name": [
                "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Garc\u00eda-Arredondo", 
            "givenName": "Alejandro", 
            "id": "sg:person.01331515462.63", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331515462.63"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.412861.8", 
              "name": [
                "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rojas-Molina", 
            "givenName": "Alejandra", 
            "id": "sg:person.01317266232.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317266232.04"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.412861.8", 
              "name": [
                "Departamento de Investigaci\u00f3n Qu\u00edmica y Farmacol\u00f3gica de Productos Naturales, Facultad de Qu\u00edmica, Universidad Aut\u00f3noma de Quer\u00e9taro, 76010, Quer\u00e9taro, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ibarra-Alvarado", 
            "givenName": "C\u00e9sar", 
            "id": "sg:person.01203037632.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203037632.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510, Mexico City, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.9486.3", 
              "name": [
                "Departamento de Ciencias de la Salud, Universidad Aut\u00f3noma Metropolitana, Campus Iztapalapa, 09340, Mexico City, Mexico", 
                "Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510, Mexico City, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lazcano-P\u00e9rez", 
            "givenName": "Fernando", 
            "id": "sg:person.01076463647.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076463647.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510, Mexico City, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.9486.3", 
              "name": [
                "Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510, Mexico City, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Arregu\u00edn-Espinosa", 
            "givenName": "Roberto", 
            "id": "sg:person.01124126367.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124126367.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Unidad Acad\u00e9mica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 77500, Puerto Morelos, Quintana Roo, Mexico", 
              "id": "http://www.grid.ac/institutes/grid.9486.3", 
              "name": [
                "Unidad Acad\u00e9mica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 77500, Puerto Morelos, Quintana Roo, Mexico"
              ], 
              "type": "Organization"
            }, 
            "familyName": "S\u00e1nchez-Rodr\u00edguez", 
            "givenName": "Judith", 
            "id": "sg:person.01336051725.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336051725.54"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1186/1678-9199-20-49", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009117936", 
              "https://doi.org/10.1186/1678-9199-20-49"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10126-005-5093-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031048091", 
              "https://doi.org/10.1007/s10126-005-5093-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-10-564", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017975749", 
              "https://doi.org/10.1186/1471-2164-10-564"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-10-290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021146111", 
              "https://doi.org/10.1186/1471-2164-10-290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12864-015-1976-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022725252", 
              "https://doi.org/10.1186/s12864-015-1976-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s40409-015-0042-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045571883", 
              "https://doi.org/10.1186/s40409-015-0042-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s40409-015-0017-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030056932", 
              "https://doi.org/10.1186/s40409-015-0017-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/227680a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010419937", 
              "https://doi.org/10.1038/227680a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00284-013-0516-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031773136", 
              "https://doi.org/10.1007/s00284-013-0516-1"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016-11-24", 
        "datePublishedReg": "2016-11-24", 
        "description": "BackgroundScleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea, three scleractinian corals from the Mexican Caribbean, have been assessed for the first time.MethodsToxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the nociceptive activity was evaluated by the formalin test. The presence of phospholipases A2 (PLA2), serine proteases, and hyaluronidases was determined by enzymatic methods. Low-molecular-weight fractions were obtained by gel filtration chromatography and ultrafiltration.ResultsExtracts from the three species were toxic to crickets, induced hemolysis in human and rat erythrocytes, produced vasoconstriction on isolated rat aortic rings, and presented phospholipase A2 and serine-protease activity. Despite the fact that these corals are not considered to be harmless to humans, the extracts generated significant nociceptive responses. The matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of the low-molecular-weight fractions revealed the presence of peptides within a mass range of 3000 to 6000\u00a0Da. These fractions were toxic to crickets and two of them induced a transitory vasoconstrictor effect on isolated rat aortic rings.ConclusionThis study suggests that scleractinian corals produce low-molecular-weight peptides that are lethal to crickets and induce vasoconstriction.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/s40409-016-0087-2", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1357529", 
            "issn": [
              "1678-9180", 
              "1678-9199"
            ], 
            "name": "Journal of Venomous Animals and Toxins including Tropical Diseases", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "22"
          }
        ], 
        "keywords": [
          "scleractinian corals", 
          "Pseudodiploria strigosa", 
          "Porites astreoides", 
          "Mexican Caribbean", 
          "phospholipases A2", 
          "biological activity", 
          "matrix-assisted laser desorption/ionization time", 
          "flight mass spectrometry analysis", 
          "laser desorption/ionization time", 
          "ecological importance", 
          "mass spectrometry analysis", 
          "coral reefs", 
          "desorption/ionization time", 
          "serine protease activity", 
          "corals", 
          "gel filtration chromatography", 
          "serine proteases", 
          "astreoides", 
          "Siderastrea", 
          "spectrometry analysis", 
          "strigosa", 
          "ionization time", 
          "crickets", 
          "presence of peptides", 
          "filtration chromatography", 
          "phospholipase A2", 
          "cnidarians", 
          "peptides", 
          "reefs", 
          "weight peptides", 
          "species", 
          "cytolysin", 
          "diversity", 
          "abundance", 
          "activity", 
          "protease", 
          "extract", 
          "humans", 
          "first time", 
          "rat aortic rings", 
          "A2", 
          "Caribbean", 
          "rat erythrocytes", 
          "toxin", 
          "aqueous extract", 
          "composition", 
          "significant nociceptive response", 
          "presence", 
          "DA", 
          "erythrocytes", 
          "fraction", 
          "enzymatic method", 
          "aortic rings", 
          "response", 
          "hyaluronidase", 
          "chromatography", 
          "importance", 
          "study", 
          "hemolysis", 
          "analysis", 
          "mass range", 
          "ring", 
          "effect", 
          "chemical composition", 
          "range", 
          "information", 
          "time", 
          "isolated rat aortic rings", 
          "fact", 
          "ConclusionThis study", 
          "world", 
          "weight fraction", 
          "nociceptive activity", 
          "ultrafiltration", 
          "method", 
          "test", 
          "vasoconstriction", 
          "nociceptive responses", 
          "vasoconstrictor activity", 
          "formalin test", 
          "vasoconstrictor effect"
        ], 
        "name": "Composition and biological activities of the aqueous extracts of three scleractinian corals from the Mexican Caribbean: Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea", 
        "pagination": "32", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1034579061"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s40409-016-0087-2"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "27904505"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s40409-016-0087-2", 
          "https://app.dimensions.ai/details/publication/pub.1034579061"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-11-24T21:00", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_703.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/s40409-016-0087-2"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40409-016-0087-2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40409-016-0087-2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40409-016-0087-2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40409-016-0087-2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    219 TRIPLES      21 PREDICATES      115 URIs      98 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s40409-016-0087-2 schema:about anzsrc-for:06
    2 anzsrc-for:0602
    3 schema:author N49789e1d266744818ede2ff98ef81970
    4 schema:citation sg:pub.10.1007/s00284-013-0516-1
    5 sg:pub.10.1007/s10126-005-5093-2
    6 sg:pub.10.1038/227680a0
    7 sg:pub.10.1186/1471-2164-10-290
    8 sg:pub.10.1186/1471-2164-10-564
    9 sg:pub.10.1186/1678-9199-20-49
    10 sg:pub.10.1186/s12864-015-1976-4
    11 sg:pub.10.1186/s40409-015-0017-8
    12 sg:pub.10.1186/s40409-015-0042-7
    13 schema:datePublished 2016-11-24
    14 schema:datePublishedReg 2016-11-24
    15 schema:description BackgroundScleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea, three scleractinian corals from the Mexican Caribbean, have been assessed for the first time.MethodsToxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the nociceptive activity was evaluated by the formalin test. The presence of phospholipases A2 (PLA2), serine proteases, and hyaluronidases was determined by enzymatic methods. Low-molecular-weight fractions were obtained by gel filtration chromatography and ultrafiltration.ResultsExtracts from the three species were toxic to crickets, induced hemolysis in human and rat erythrocytes, produced vasoconstriction on isolated rat aortic rings, and presented phospholipase A2 and serine-protease activity. Despite the fact that these corals are not considered to be harmless to humans, the extracts generated significant nociceptive responses. The matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of the low-molecular-weight fractions revealed the presence of peptides within a mass range of 3000 to 6000 Da. These fractions were toxic to crickets and two of them induced a transitory vasoconstrictor effect on isolated rat aortic rings.ConclusionThis study suggests that scleractinian corals produce low-molecular-weight peptides that are lethal to crickets and induce vasoconstriction.
    16 schema:genre article
    17 schema:isAccessibleForFree true
    18 schema:isPartOf N2ab90c67061c4eb486879b080df583b0
    19 Ncb8ec6432cfe444aa39b6e0ed2fb3d50
    20 sg:journal.1357529
    21 schema:keywords A2
    22 Caribbean
    23 ConclusionThis study
    24 DA
    25 Mexican Caribbean
    26 Porites astreoides
    27 Pseudodiploria strigosa
    28 Siderastrea
    29 abundance
    30 activity
    31 analysis
    32 aortic rings
    33 aqueous extract
    34 astreoides
    35 biological activity
    36 chemical composition
    37 chromatography
    38 cnidarians
    39 composition
    40 coral reefs
    41 corals
    42 crickets
    43 cytolysin
    44 desorption/ionization time
    45 diversity
    46 ecological importance
    47 effect
    48 enzymatic method
    49 erythrocytes
    50 extract
    51 fact
    52 filtration chromatography
    53 first time
    54 flight mass spectrometry analysis
    55 formalin test
    56 fraction
    57 gel filtration chromatography
    58 hemolysis
    59 humans
    60 hyaluronidase
    61 importance
    62 information
    63 ionization time
    64 isolated rat aortic rings
    65 laser desorption/ionization time
    66 mass range
    67 mass spectrometry analysis
    68 matrix-assisted laser desorption/ionization time
    69 method
    70 nociceptive activity
    71 nociceptive responses
    72 peptides
    73 phospholipase A2
    74 phospholipases A2
    75 presence
    76 presence of peptides
    77 protease
    78 range
    79 rat aortic rings
    80 rat erythrocytes
    81 reefs
    82 response
    83 ring
    84 scleractinian corals
    85 serine protease activity
    86 serine proteases
    87 significant nociceptive response
    88 species
    89 spectrometry analysis
    90 strigosa
    91 study
    92 test
    93 time
    94 toxin
    95 ultrafiltration
    96 vasoconstriction
    97 vasoconstrictor activity
    98 vasoconstrictor effect
    99 weight fraction
    100 weight peptides
    101 world
    102 schema:name Composition and biological activities of the aqueous extracts of three scleractinian corals from the Mexican Caribbean: Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea
    103 schema:pagination 32
    104 schema:productId N537807ba6bbf4c98a8f30471463f112f
    105 N8f9288b971f6436496f25f9a6068c116
    106 Nebaba3fc81bc48669b4fb0c1efe0ef71
    107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034579061
    108 https://doi.org/10.1186/s40409-016-0087-2
    109 schema:sdDatePublished 2022-11-24T21:00
    110 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    111 schema:sdPublisher N2e50f7c3dc84416da2e1d561ed1843a0
    112 schema:url https://doi.org/10.1186/s40409-016-0087-2
    113 sgo:license sg:explorer/license/
    114 sgo:sdDataset articles
    115 rdf:type schema:ScholarlyArticle
    116 N1e200efef025472e970741399e5206fc rdf:first sg:person.01076463647.13
    117 rdf:rest N8248a52af1af47ba91e22248c9b8963d
    118 N2ab90c67061c4eb486879b080df583b0 schema:volumeNumber 22
    119 rdf:type schema:PublicationVolume
    120 N2e50f7c3dc84416da2e1d561ed1843a0 schema:name Springer Nature - SN SciGraph project
    121 rdf:type schema:Organization
    122 N4271180935b44fa8942fb80c2f209769 rdf:first sg:person.01203037632.22
    123 rdf:rest N1e200efef025472e970741399e5206fc
    124 N49789e1d266744818ede2ff98ef81970 rdf:first sg:person.01331515462.63
    125 rdf:rest Ncb3a83f9a0494c7da72231e4c7295152
    126 N537807ba6bbf4c98a8f30471463f112f schema:name doi
    127 schema:value 10.1186/s40409-016-0087-2
    128 rdf:type schema:PropertyValue
    129 N5b96f38921b14ff6a932f1020dba6aae rdf:first sg:person.01336051725.54
    130 rdf:rest rdf:nil
    131 N8248a52af1af47ba91e22248c9b8963d rdf:first sg:person.01124126367.10
    132 rdf:rest N5b96f38921b14ff6a932f1020dba6aae
    133 N8f9288b971f6436496f25f9a6068c116 schema:name pubmed_id
    134 schema:value 27904505
    135 rdf:type schema:PropertyValue
    136 Ncb3a83f9a0494c7da72231e4c7295152 rdf:first sg:person.01317266232.04
    137 rdf:rest N4271180935b44fa8942fb80c2f209769
    138 Ncb8ec6432cfe444aa39b6e0ed2fb3d50 schema:issueNumber 1
    139 rdf:type schema:PublicationIssue
    140 Nebaba3fc81bc48669b4fb0c1efe0ef71 schema:name dimensions_id
    141 schema:value pub.1034579061
    142 rdf:type schema:PropertyValue
    143 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    144 schema:name Biological Sciences
    145 rdf:type schema:DefinedTerm
    146 anzsrc-for:0602 schema:inDefinedTermSet anzsrc-for:
    147 schema:name Ecology
    148 rdf:type schema:DefinedTerm
    149 sg:journal.1357529 schema:issn 1678-9180
    150 1678-9199
    151 schema:name Journal of Venomous Animals and Toxins including Tropical Diseases
    152 schema:publisher Springer Nature
    153 rdf:type schema:Periodical
    154 sg:person.01076463647.13 schema:affiliation grid-institutes:grid.9486.3
    155 schema:familyName Lazcano-Pérez
    156 schema:givenName Fernando
    157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076463647.13
    158 rdf:type schema:Person
    159 sg:person.01124126367.10 schema:affiliation grid-institutes:grid.9486.3
    160 schema:familyName Arreguín-Espinosa
    161 schema:givenName Roberto
    162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124126367.10
    163 rdf:type schema:Person
    164 sg:person.01203037632.22 schema:affiliation grid-institutes:grid.412861.8
    165 schema:familyName Ibarra-Alvarado
    166 schema:givenName César
    167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203037632.22
    168 rdf:type schema:Person
    169 sg:person.01317266232.04 schema:affiliation grid-institutes:grid.412861.8
    170 schema:familyName Rojas-Molina
    171 schema:givenName Alejandra
    172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317266232.04
    173 rdf:type schema:Person
    174 sg:person.01331515462.63 schema:affiliation grid-institutes:grid.412861.8
    175 schema:familyName García-Arredondo
    176 schema:givenName Alejandro
    177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331515462.63
    178 rdf:type schema:Person
    179 sg:person.01336051725.54 schema:affiliation grid-institutes:grid.9486.3
    180 schema:familyName Sánchez-Rodríguez
    181 schema:givenName Judith
    182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336051725.54
    183 rdf:type schema:Person
    184 sg:pub.10.1007/s00284-013-0516-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031773136
    185 https://doi.org/10.1007/s00284-013-0516-1
    186 rdf:type schema:CreativeWork
    187 sg:pub.10.1007/s10126-005-5093-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031048091
    188 https://doi.org/10.1007/s10126-005-5093-2
    189 rdf:type schema:CreativeWork
    190 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
    191 https://doi.org/10.1038/227680a0
    192 rdf:type schema:CreativeWork
    193 sg:pub.10.1186/1471-2164-10-290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021146111
    194 https://doi.org/10.1186/1471-2164-10-290
    195 rdf:type schema:CreativeWork
    196 sg:pub.10.1186/1471-2164-10-564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017975749
    197 https://doi.org/10.1186/1471-2164-10-564
    198 rdf:type schema:CreativeWork
    199 sg:pub.10.1186/1678-9199-20-49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009117936
    200 https://doi.org/10.1186/1678-9199-20-49
    201 rdf:type schema:CreativeWork
    202 sg:pub.10.1186/s12864-015-1976-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022725252
    203 https://doi.org/10.1186/s12864-015-1976-4
    204 rdf:type schema:CreativeWork
    205 sg:pub.10.1186/s40409-015-0017-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030056932
    206 https://doi.org/10.1186/s40409-015-0017-8
    207 rdf:type schema:CreativeWork
    208 sg:pub.10.1186/s40409-015-0042-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045571883
    209 https://doi.org/10.1186/s40409-015-0042-7
    210 rdf:type schema:CreativeWork
    211 grid-institutes:grid.412861.8 schema:alternateName Departamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, 76010, Querétaro, Mexico
    212 schema:name Departamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, 76010, Querétaro, Mexico
    213 rdf:type schema:Organization
    214 grid-institutes:grid.9486.3 schema:alternateName Instituto de Química, Universidad Nacional Autónoma de México, 04510, Mexico City, Mexico
    215 Unidad Académica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, 77500, Puerto Morelos, Quintana Roo, Mexico
    216 schema:name Departamento de Ciencias de la Salud, Universidad Autónoma Metropolitana, Campus Iztapalapa, 09340, Mexico City, Mexico
    217 Instituto de Química, Universidad Nacional Autónoma de México, 04510, Mexico City, Mexico
    218 Unidad Académica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, 77500, Puerto Morelos, Quintana Roo, Mexico
    219 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...