Gender development and hepatitis B and C infections among pregnant women in Africa: a systematic review and meta-analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Jean Joel Bigna, Angeladine M. Kenne, Aghiles Hamroun, Marie S. Ndangang, Audrey Joyce Foka, Dahlia Noelle Tounouga, Rémi Lenain, Marie A. Amougou, Jobert Richie Nansseu

ABSTRACT

BACKGROUND: Although Africa is a region of hyper endemicity to viral hepatitis B (HBV) and C (HCV) infections, there is limited data on their related burden among pregnant women. The present systematic review and meta-analysis aimed to determine the magnitude of these infections among pregnant women living in Africa and investigate its association with gender-related human development indicators. MAIN TEXT: We searched PubMed, Embase, Web of Science, Africa Journal Online, and Global Index Medicus, with no language restriction, to identify observational studies on HBV and HCV infections in pregnant women residing in Africa published from January 1, 2000 until December 31, 2017. Eligible studies reported the prevalence of HBV and/or HCV infection(s) (HBs antigen and HCV antibodies) and/or infectivity (HBe antigen or detectable HCV viral load). Each study was independently reviewed for methodological quality. We used a random-effects model meta-analysis to pool studies. In total, 145 studies (258 251 participants, 30 countries) were included, of which 120 (82.8%) had a low, 24 (16.5%) a moderate, and one (0.7%) had a high risk of bias. The prevalence of HBV and HCV infections was 6.8% (95% confidence interval [CI]: 6.1-7.6, 113 studies) and 3.4% (95% CI: 2.6-4.2, 58 studies), respectively. The prevalence of HBe antigen and HCV detectable viral load was 18.9% (95% CI: 14.4-23.9) and 62.3% (95% CI: 51.6-72.5) in HBV positive and HCV positive pregnant women, respectively. The multivariable meta-regression analysis showed that the prevalence of HBV infection increased with decreasing gender development index, males' level of education and females' expected years of schooling. Furthermore, this prevalence was higher in rural areas and in western and central Africa. The prevalence of HCV infection increased with decreasing proportion of seats held by women in parliament. CONCLUSIONS: To address the burden of HBV and HCV infections, beyond well-known risk factors at the individual-level, macro-level factors including gender-related human development indicators and dwelling in rural areas should be considered. In Africa, HBV or HCV infected mothers seems to have high potential of transmission to their children. More... »

PAGES

16

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40249-019-0526-8

DOI

http://dx.doi.org/10.1186/s40249-019-0526-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112511674

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30827278


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Africa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis B", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy Complications, Infectious", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Socioeconomic Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Paris-Sud", 
          "id": "https://www.grid.ac/institutes/grid.5842.b", 
          "name": [
            "Department of Epidemiology and Public Health, Centre Pasteur of Cameroon, P.O. Box 1274, Yaound\u00e9, Cameroon", 
            "Faculty of Medicine, University of Paris Sud, Le Kremlin-Bicetre, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bigna", 
        "givenName": "Jean Joel", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Epidemiology and Public Health, Centre Pasteur of Cameroon, P.O. Box 1274, Yaound\u00e9, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kenne", 
        "givenName": "Angeladine M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Regional et Universitaire de Lille", 
          "id": "https://www.grid.ac/institutes/grid.410463.4", 
          "name": [
            "Faculty of Medicine, University of Paris Sud, Le Kremlin-Bicetre, France", 
            "Department of Nephrology, Huriez Hospital, Lille University Hospital, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hamroun", 
        "givenName": "Aghiles", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire De Rouen", 
          "id": "https://www.grid.ac/institutes/grid.41724.34", 
          "name": [
            "Department of Medical Information and Informatics, Rouen University Hospital, Rouen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ndangang", 
        "givenName": "Marie S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e9 de Yaound\u00e9 I", 
          "id": "https://www.grid.ac/institutes/grid.412661.6", 
          "name": [
            "Faculty of Medicine and Biomedical Sciences, University of Yaound\u00e9 I, Yaound\u00e9, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Foka", 
        "givenName": "Audrey Joyce", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e9 de Yaound\u00e9 I", 
          "id": "https://www.grid.ac/institutes/grid.412661.6", 
          "name": [
            "Faculty of Medicine and Biomedical Sciences, University of Yaound\u00e9 I, Yaound\u00e9, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tounouga", 
        "givenName": "Dahlia Noelle", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nantes", 
          "id": "https://www.grid.ac/institutes/grid.4817.a", 
          "name": [
            "Department of Nephrology, Huriez Hospital, Lille University Hospital, Lille, France", 
            "MethodS in Patient-centered outcomes & HEalth ResEarch (EA 4275 SPHERE), Nantes University, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lenain", 
        "givenName": "R\u00e9mi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e9 de Yaound\u00e9 I", 
          "id": "https://www.grid.ac/institutes/grid.412661.6", 
          "name": [
            "Department of Virology, Centre Pasteur of Cameroon, Yaound\u00e9, Cameroon", 
            "Faculty of Sciences, University of Yaound\u00e9 I, Yaound\u00e9, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amougou", 
        "givenName": "Marie A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e9 de Yaound\u00e9 I", 
          "id": "https://www.grid.ac/institutes/grid.412661.6", 
          "name": [
            "Department for the Control of Disease, Epidemics and Pandemics, Ministry of Public Health, Yaound\u00e9, Cameroon", 
            "Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaound\u00e9 I, Yaound\u00e9, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nansseu", 
        "givenName": "Jobert Richie", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2011.11.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001012048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jech-2013-203104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008174542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrgastro.2013.179", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009957758", 
          "https://doi.org/10.1038/nrgastro.2013.179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jp.2014.167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017055368", 
          "https://doi.org/10.1038/jp.2014.167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jp.2014.167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017055368", 
          "https://doi.org/10.1038/jp.2014.167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0891-5520(05)70188-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017494796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0891-5520(05)70188-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017494796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fpsyg.2015.00779", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020377887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.38719.435833.7c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023984852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2893.2011.01436.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024024613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jpids/piu064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024602298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12879-016-1584-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041202198", 
          "https://doi.org/10.1186/s12879-016-1584-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12879-016-1584-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041202198", 
          "https://doi.org/10.1186/s12879-016-1584-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1728-4457.2011.00412.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045491342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.1186", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047418980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1473-3099(02)00264-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048735167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2334-12-131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052961529", 
          "https://doi.org/10.1186/1471-2334-12-131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7109.629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062780726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7109.629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062780726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3001666", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070163933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3855/jidc.3243", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071482609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077050211", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmjopen-2016-015298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090397530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmjopen-2016-015298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090397530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmjopen-2016-015748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091382661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18597/rcog.3071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092146793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2468-1253(17)30295-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092596896"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Although Africa is a region of hyper endemicity to viral hepatitis B (HBV) and C (HCV) infections, there is limited data on their related burden among pregnant women. The present systematic review and meta-analysis aimed to determine the magnitude of these infections among pregnant women living in Africa and investigate its association with gender-related human development indicators.\nMAIN TEXT: We searched PubMed, Embase, Web of Science, Africa Journal Online, and Global Index Medicus, with no language restriction, to identify observational studies on HBV and HCV infections in pregnant women residing in Africa published from January 1, 2000 until December 31, 2017. Eligible studies reported the prevalence of HBV and/or HCV infection(s) (HBs antigen and HCV antibodies) and/or infectivity (HBe antigen or detectable HCV viral load). Each study was independently reviewed for methodological quality. We used a random-effects model meta-analysis to pool studies. In total, 145 studies (258\u2009251 participants, 30 countries) were included, of which 120 (82.8%) had a low, 24 (16.5%) a moderate, and one (0.7%) had a high risk of bias. The prevalence of HBV and HCV infections was 6.8% (95% confidence interval [CI]: 6.1-7.6, 113 studies) and 3.4% (95% CI: 2.6-4.2, 58 studies), respectively. The prevalence of HBe antigen and HCV detectable viral load was 18.9% (95% CI: 14.4-23.9) and 62.3% (95% CI: 51.6-72.5) in HBV positive and HCV positive pregnant women, respectively. The multivariable meta-regression analysis showed that the prevalence of HBV infection increased with decreasing gender development index, males' level of education and females' expected years of schooling. Furthermore, this prevalence was higher in rural areas and in western and central Africa. The prevalence of HCV infection increased with decreasing proportion of seats held by women in parliament.\nCONCLUSIONS: To address the burden of HBV and HCV infections, beyond well-known risk factors at the individual-level, macro-level factors including gender-related human development indicators and dwelling in rural areas should be considered. In Africa, HBV or HCV infected mothers seems to have high potential of transmission to their children.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s40249-019-0526-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1048296", 
        "issn": [
          "2095-5162", 
          "2049-9957"
        ], 
        "name": "Infectious Diseases of Poverty", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Gender development and hepatitis B and C infections among pregnant women in Africa: a systematic review and meta-analysis", 
    "pagination": "16", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d8f8edd1e47e214f5b3833f136b0babd65b37496c67797b7da07cc7a7b76965e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30827278"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101606645"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s40249-019-0526-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112511674"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s40249-019-0526-8", 
      "https://app.dimensions.ai/details/publication/pub.1112511674"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78964_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs40249-019-0526-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40249-019-0526-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40249-019-0526-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40249-019-0526-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40249-019-0526-8'


 

This table displays all metadata directly associated to this object as RDF triples.

250 TRIPLES      21 PREDICATES      62 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s40249-019-0526-8 schema:about N0019bfe995e94b6eb6fb4c2726171e59
2 N07523c5d250946b1bdf3e29bd3a6b604
3 N0b5ce4ca21114b74b10c1f7a8e0f13d1
4 N15e8efb003724aef87f8241c7d5dcbe7
5 N48d2c04f681c4a1db6f204ff302d22b8
6 N6009fc29b76d426f9a5624b66477195d
7 N770c59af5b89487db0c4432e1b1b2ca2
8 Nb11688d6ce24478f876db58c5a8c2f86
9 Ne4d258ba554b4cb8ac3cd08c77263a62
10 Nebcb037a72c54b74bd353fa2086c15a5
11 Nfecceb13f84247ff9a7147aaafb41da1
12 anzsrc-for:11
13 anzsrc-for:1117
14 schema:author N1570ddb14ea849b7b2e139ec67061e24
15 schema:citation sg:pub.10.1038/jp.2014.167
16 sg:pub.10.1038/nrgastro.2013.179
17 sg:pub.10.1186/1471-2334-12-131
18 sg:pub.10.1186/s12879-016-1584-1
19 https://app.dimensions.ai/details/publication/pub.1077050211
20 https://doi.org/10.1002/sim.1186
21 https://doi.org/10.1016/j.jclinepi.2011.11.014
22 https://doi.org/10.1016/s0891-5520(05)70188-4
23 https://doi.org/10.1016/s1473-3099(02)00264-5
24 https://doi.org/10.1016/s2468-1253(17)30295-9
25 https://doi.org/10.1093/jpids/piu064
26 https://doi.org/10.1111/j.1365-2893.2011.01436.x
27 https://doi.org/10.1111/j.1728-4457.2011.00412.x
28 https://doi.org/10.1136/bmj.315.7109.629
29 https://doi.org/10.1136/bmj.38719.435833.7c
30 https://doi.org/10.1136/bmjopen-2016-015298
31 https://doi.org/10.1136/bmjopen-2016-015748
32 https://doi.org/10.1136/jech-2013-203104
33 https://doi.org/10.18597/rcog.3071
34 https://doi.org/10.2307/3001666
35 https://doi.org/10.3389/fpsyg.2015.00779
36 https://doi.org/10.3855/jidc.3243
37 schema:datePublished 2019-12
38 schema:datePublishedReg 2019-12-01
39 schema:description BACKGROUND: Although Africa is a region of hyper endemicity to viral hepatitis B (HBV) and C (HCV) infections, there is limited data on their related burden among pregnant women. The present systematic review and meta-analysis aimed to determine the magnitude of these infections among pregnant women living in Africa and investigate its association with gender-related human development indicators. MAIN TEXT: We searched PubMed, Embase, Web of Science, Africa Journal Online, and Global Index Medicus, with no language restriction, to identify observational studies on HBV and HCV infections in pregnant women residing in Africa published from January 1, 2000 until December 31, 2017. Eligible studies reported the prevalence of HBV and/or HCV infection(s) (HBs antigen and HCV antibodies) and/or infectivity (HBe antigen or detectable HCV viral load). Each study was independently reviewed for methodological quality. We used a random-effects model meta-analysis to pool studies. In total, 145 studies (258 251 participants, 30 countries) were included, of which 120 (82.8%) had a low, 24 (16.5%) a moderate, and one (0.7%) had a high risk of bias. The prevalence of HBV and HCV infections was 6.8% (95% confidence interval [CI]: 6.1-7.6, 113 studies) and 3.4% (95% CI: 2.6-4.2, 58 studies), respectively. The prevalence of HBe antigen and HCV detectable viral load was 18.9% (95% CI: 14.4-23.9) and 62.3% (95% CI: 51.6-72.5) in HBV positive and HCV positive pregnant women, respectively. The multivariable meta-regression analysis showed that the prevalence of HBV infection increased with decreasing gender development index, males' level of education and females' expected years of schooling. Furthermore, this prevalence was higher in rural areas and in western and central Africa. The prevalence of HCV infection increased with decreasing proportion of seats held by women in parliament. CONCLUSIONS: To address the burden of HBV and HCV infections, beyond well-known risk factors at the individual-level, macro-level factors including gender-related human development indicators and dwelling in rural areas should be considered. In Africa, HBV or HCV infected mothers seems to have high potential of transmission to their children.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree true
43 schema:isPartOf N336eb2822e0b42b488e51bb7534431d6
44 Ned94dead631945a4818f68deec206e8b
45 sg:journal.1048296
46 schema:name Gender development and hepatitis B and C infections among pregnant women in Africa: a systematic review and meta-analysis
47 schema:pagination 16
48 schema:productId N03be8f44489b44fe9e5c91aad93d8a1c
49 N619b609a0ce14ecc95992ed32ed50c09
50 N7bcda21b925745eb8c3fba6b9ea9bcd2
51 Nc8cccd28a49e4261a063d8ecdaa312a2
52 Ne8f770cc034344e197ca51ba8bf3d2dc
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112511674
54 https://doi.org/10.1186/s40249-019-0526-8
55 schema:sdDatePublished 2019-04-11T13:20
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher N0674fcacef73464a93ed48923bd30530
58 schema:url https://link.springer.com/10.1186%2Fs40249-019-0526-8
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N0019bfe995e94b6eb6fb4c2726171e59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Pregnancy Complications, Infectious
64 rdf:type schema:DefinedTerm
65 N03be8f44489b44fe9e5c91aad93d8a1c schema:name doi
66 schema:value 10.1186/s40249-019-0526-8
67 rdf:type schema:PropertyValue
68 N0674fcacef73464a93ed48923bd30530 schema:name Springer Nature - SN SciGraph project
69 rdf:type schema:Organization
70 N07523c5d250946b1bdf3e29bd3a6b604 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Socioeconomic Factors
72 rdf:type schema:DefinedTerm
73 N0853d7156ebe450ea56aadf7a10dff16 rdf:first Neaf42f14e65a4bbc8caec28f60e2e75f
74 rdf:rest N8cbade329c904dfcbb5903edb5e641f8
75 N0b5ce4ca21114b74b10c1f7a8e0f13d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Humans
77 rdf:type schema:DefinedTerm
78 N1570ddb14ea849b7b2e139ec67061e24 rdf:first Nedcc6b6215f9437597ffa2b43e8b77ed
79 rdf:rest Nd42a5dd9a6ff41e7a707dd8cde2699e3
80 N15e8efb003724aef87f8241c7d5dcbe7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Hepatitis B
82 rdf:type schema:DefinedTerm
83 N16486ddc21434d43a47d745efe0baeba rdf:first Nd868b845892b4c91875cd225ac3e0858
84 rdf:rest N22e75fd89c684d2c962c19c448db06d9
85 N1fcbdc96e39d4c17a680ebecaf621998 schema:affiliation https://www.grid.ac/institutes/grid.412661.6
86 schema:familyName Nansseu
87 schema:givenName Jobert Richie
88 rdf:type schema:Person
89 N22e75fd89c684d2c962c19c448db06d9 rdf:first Nb25a26caf5e14e598e1860ba5a5eb708
90 rdf:rest N0853d7156ebe450ea56aadf7a10dff16
91 N250a82ca3109468f8d1c1a8642fde9e3 schema:affiliation https://www.grid.ac/institutes/grid.410463.4
92 schema:familyName Hamroun
93 schema:givenName Aghiles
94 rdf:type schema:Person
95 N336eb2822e0b42b488e51bb7534431d6 schema:volumeNumber 8
96 rdf:type schema:PublicationVolume
97 N48d2c04f681c4a1db6f204ff302d22b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Pregnancy
99 rdf:type schema:DefinedTerm
100 N6009fc29b76d426f9a5624b66477195d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Male
102 rdf:type schema:DefinedTerm
103 N619b609a0ce14ecc95992ed32ed50c09 schema:name dimensions_id
104 schema:value pub.1112511674
105 rdf:type schema:PropertyValue
106 N6fbf06f8420b47f1a5a904b3cd98308c rdf:first N250a82ca3109468f8d1c1a8642fde9e3
107 rdf:rest Ncacab0bc80f44cc0af2c63c326ae7352
108 N770c59af5b89487db0c4432e1b1b2ca2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Africa
110 rdf:type schema:DefinedTerm
111 N7bcda21b925745eb8c3fba6b9ea9bcd2 schema:name nlm_unique_id
112 schema:value 101606645
113 rdf:type schema:PropertyValue
114 N8108cfc8008044f889a011c0cd4cabab schema:affiliation https://www.grid.ac/institutes/grid.412661.6
115 schema:familyName Amougou
116 schema:givenName Marie A.
117 rdf:type schema:Person
118 N8c4b20cdd60f40c2acf7eb5817ba3757 rdf:first N1fcbdc96e39d4c17a680ebecaf621998
119 rdf:rest rdf:nil
120 N8cbade329c904dfcbb5903edb5e641f8 rdf:first N8108cfc8008044f889a011c0cd4cabab
121 rdf:rest N8c4b20cdd60f40c2acf7eb5817ba3757
122 N9a8b41e12a6e4d05b670e6adf81ca438 schema:affiliation Ne9da29e503c94ba0b0ac2b384c0e4137
123 schema:familyName Kenne
124 schema:givenName Angeladine M.
125 rdf:type schema:Person
126 Nb11688d6ce24478f876db58c5a8c2f86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Sex Factors
128 rdf:type schema:DefinedTerm
129 Nb25a26caf5e14e598e1860ba5a5eb708 schema:affiliation https://www.grid.ac/institutes/grid.412661.6
130 schema:familyName Tounouga
131 schema:givenName Dahlia Noelle
132 rdf:type schema:Person
133 Nc8cccd28a49e4261a063d8ecdaa312a2 schema:name pubmed_id
134 schema:value 30827278
135 rdf:type schema:PropertyValue
136 Ncacab0bc80f44cc0af2c63c326ae7352 rdf:first Ne840b85fb1bd4f259595a338c3ae2851
137 rdf:rest N16486ddc21434d43a47d745efe0baeba
138 Nd42a5dd9a6ff41e7a707dd8cde2699e3 rdf:first N9a8b41e12a6e4d05b670e6adf81ca438
139 rdf:rest N6fbf06f8420b47f1a5a904b3cd98308c
140 Nd868b845892b4c91875cd225ac3e0858 schema:affiliation https://www.grid.ac/institutes/grid.412661.6
141 schema:familyName Foka
142 schema:givenName Audrey Joyce
143 rdf:type schema:Person
144 Ne4d258ba554b4cb8ac3cd08c77263a62 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Female
146 rdf:type schema:DefinedTerm
147 Ne840b85fb1bd4f259595a338c3ae2851 schema:affiliation https://www.grid.ac/institutes/grid.41724.34
148 schema:familyName Ndangang
149 schema:givenName Marie S.
150 rdf:type schema:Person
151 Ne8f770cc034344e197ca51ba8bf3d2dc schema:name readcube_id
152 schema:value d8f8edd1e47e214f5b3833f136b0babd65b37496c67797b7da07cc7a7b76965e
153 rdf:type schema:PropertyValue
154 Ne9da29e503c94ba0b0ac2b384c0e4137 schema:name Department of Epidemiology and Public Health, Centre Pasteur of Cameroon, P.O. Box 1274, Yaoundé, Cameroon
155 rdf:type schema:Organization
156 Neaf42f14e65a4bbc8caec28f60e2e75f schema:affiliation https://www.grid.ac/institutes/grid.4817.a
157 schema:familyName Lenain
158 schema:givenName Rémi
159 rdf:type schema:Person
160 Nebcb037a72c54b74bd353fa2086c15a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Hepatitis C
162 rdf:type schema:DefinedTerm
163 Ned94dead631945a4818f68deec206e8b schema:issueNumber 1
164 rdf:type schema:PublicationIssue
165 Nedcc6b6215f9437597ffa2b43e8b77ed schema:affiliation https://www.grid.ac/institutes/grid.5842.b
166 schema:familyName Bigna
167 schema:givenName Jean Joel
168 rdf:type schema:Person
169 Nfecceb13f84247ff9a7147aaafb41da1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Prevalence
171 rdf:type schema:DefinedTerm
172 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
173 schema:name Medical and Health Sciences
174 rdf:type schema:DefinedTerm
175 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
176 schema:name Public Health and Health Services
177 rdf:type schema:DefinedTerm
178 sg:journal.1048296 schema:issn 2049-9957
179 2095-5162
180 schema:name Infectious Diseases of Poverty
181 rdf:type schema:Periodical
182 sg:pub.10.1038/jp.2014.167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017055368
183 https://doi.org/10.1038/jp.2014.167
184 rdf:type schema:CreativeWork
185 sg:pub.10.1038/nrgastro.2013.179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009957758
186 https://doi.org/10.1038/nrgastro.2013.179
187 rdf:type schema:CreativeWork
188 sg:pub.10.1186/1471-2334-12-131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052961529
189 https://doi.org/10.1186/1471-2334-12-131
190 rdf:type schema:CreativeWork
191 sg:pub.10.1186/s12879-016-1584-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041202198
192 https://doi.org/10.1186/s12879-016-1584-1
193 rdf:type schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1077050211 schema:CreativeWork
195 https://doi.org/10.1002/sim.1186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047418980
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/j.jclinepi.2011.11.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001012048
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/s0891-5520(05)70188-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017494796
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/s1473-3099(02)00264-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048735167
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/s2468-1253(17)30295-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092596896
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1093/jpids/piu064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024602298
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1111/j.1365-2893.2011.01436.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024024613
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1111/j.1728-4457.2011.00412.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1045491342
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1136/bmj.315.7109.629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062780726
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1136/bmj.38719.435833.7c schema:sameAs https://app.dimensions.ai/details/publication/pub.1023984852
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1136/bmjopen-2016-015298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090397530
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1136/bmjopen-2016-015748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091382661
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1136/jech-2013-203104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008174542
220 rdf:type schema:CreativeWork
221 https://doi.org/10.18597/rcog.3071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092146793
222 rdf:type schema:CreativeWork
223 https://doi.org/10.2307/3001666 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070163933
224 rdf:type schema:CreativeWork
225 https://doi.org/10.3389/fpsyg.2015.00779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020377887
226 rdf:type schema:CreativeWork
227 https://doi.org/10.3855/jidc.3243 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071482609
228 rdf:type schema:CreativeWork
229 https://www.grid.ac/institutes/grid.410463.4 schema:alternateName Centre Hospitalier Regional et Universitaire de Lille
230 schema:name Department of Nephrology, Huriez Hospital, Lille University Hospital, Lille, France
231 Faculty of Medicine, University of Paris Sud, Le Kremlin-Bicetre, France
232 rdf:type schema:Organization
233 https://www.grid.ac/institutes/grid.412661.6 schema:alternateName Université de Yaoundé I
234 schema:name Department for the Control of Disease, Epidemics and Pandemics, Ministry of Public Health, Yaoundé, Cameroon
235 Department of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
236 Department of Virology, Centre Pasteur of Cameroon, Yaoundé, Cameroon
237 Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
238 Faculty of Sciences, University of Yaoundé I, Yaoundé, Cameroon
239 rdf:type schema:Organization
240 https://www.grid.ac/institutes/grid.41724.34 schema:alternateName Centre Hospitalier Universitaire De Rouen
241 schema:name Department of Medical Information and Informatics, Rouen University Hospital, Rouen, France
242 rdf:type schema:Organization
243 https://www.grid.ac/institutes/grid.4817.a schema:alternateName University of Nantes
244 schema:name Department of Nephrology, Huriez Hospital, Lille University Hospital, Lille, France
245 MethodS in Patient-centered outcomes & HEalth ResEarch (EA 4275 SPHERE), Nantes University, Nantes, France
246 rdf:type schema:Organization
247 https://www.grid.ac/institutes/grid.5842.b schema:alternateName University of Paris-Sud
248 schema:name Department of Epidemiology and Public Health, Centre Pasteur of Cameroon, P.O. Box 1274, Yaoundé, Cameroon
249 Faculty of Medicine, University of Paris Sud, Le Kremlin-Bicetre, France
250 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...