A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Valery V. Wojciechowski, Daniela Calina, Konstantinos Tsarouhas, Alexander V. Pivnik, Alexander A. Sergievich, Vladimir V. Kodintsev, Ekaterina A. Filatova, Eren Ozcagli, Anca Oana Docea, Andreea Letitia Arsene, Eliza Gofita, Christina Tsitsimpikou, Aristidis M. Tsatsakis, Kirill S. Golokhvast

ABSTRACT

Physicians often come across with cases of vitamin K antagonists-dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagulants of indirect action or not reported administration of vitamin K antagonists due to memory impairment and/or other mental disorders, even deliberate use thereof (attempt to murder or suicide). Rodenticide-poisoning (coumarins, warfarins) via food or occupational accidents are difficult to diagnose. This article discusses different types of acquired vitamin K-dependent coagulopathy. Differential diagnosis is primarily based on patient statements before additional causes of vitamin K deficiency are explored. Even when pathological vitamin K deficiency is not determined, appropriate and urgent medical treatment is necessary: administration of fresh frozen plasma or concentrated factors of the prothrombin complex, administration of vitamin K remedies along with symptomatic therapy. With early diagnosis and prescription of appropriate therapy, prognosis is favorable. Reasons for vitamin K antagonists-dependent coagulopathy cases. More... »

PAGES

10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40199-017-0175-z

DOI

http://dx.doi.org/10.1186/s40199-017-0175-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084863003

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28416008


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