Dietary supplementation of Bacillus subtilis influenced intestinal health of weaned pigs experimentally infected with a pathogenic E. coli View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-06-25

AUTHORS

Kwangwook Kim, Yijie He, Xia Xiong, Amy Ehrlich, Xunde Li, Helen Raybould, Edward R. Atwill, Elizabeth A. Maga, Jens Jørgensen, Yanhong Liu

ABSTRACT

BackgroundThere is growing evidence to support the beneficial effects of supplementing direct-fed microbials (DFM) on performance, health status, and immune responses of weaned pigs. Therefore, the objective of this study was to investigate dietary supplementation of Bacillus subtilis (DSM 25841) on growth performance, diarrhea, gut permeability and immunity of weaned pigs experimentally infected with a pathogenic F-18 Escherichia coli (E. coli).ResultsThe F18 E. coli infection reduced (P < 0.05) growth performance and intestinal villi height, whereas increased (P < 0.05) diarrhea and transcellular and paracellular permeability in the jejunum compared with non-challenged control. Supplementation of Bacillus subtilis linearly enhanced average daily gain of E. coli infected pigs from d 0 to 5 post-inoculation (PI) (P < 0.05) and d 0 to 11 PI (P = 0.058). Supplementation of high dose of Bacillus subtilis reduced (P < 0.05) both transcellular and paracellular permeability on d 5 and d 11 PI compared with the E. coli infected pigs fed with control diet. E. coli infection up-regulated (P < 0.05) the mRNA expression of SLC5A10 (soluble carrier family 5 member 10) and MUC2 (mucin 2) on d 5 PI, but down-regulated (P < 0.05) expression of SLC5A10, MUC2, and CLDN1 on d 11 PI in jejunal mucosa when pigs were fed with the control diet. Supplementation of Bacillus subtilis linearly up-regulated (P < 0.05) the mRNA expression of CFTR and ZO1 on d 5 PI and SLC5A10 and MUC2 on d 11 PI in jejunal mucosa of E. coli infected pigs. In addition, E. coli infection increased (P < 0.05) the mRNA expression of several immune genes (IL1A, IL1B, and IL7 on d 5 PI, and IL1B, IL6, IL7, and TNF on d 11 PI) in the ileal mucosa of weaned pigs. Inclusion of Bacillus subtilis to control diet linearly down-regulated gene expression of IL1A on d 5 PI (P = 0.07) and IL6 on d 11 PI (P < 0.05) in ileal mucosa of E. coli infected pigs.ConclusionsSupplementation of Bacillus subtilis (DSM 25841) enhanced growth rate and improved gut barrier function of weaned pigs experimentally infected with a pathogenic E. coli. More... »

PAGES

52

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40104-019-0364-3

DOI

http://dx.doi.org/10.1186/s40104-019-0364-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1117485716


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/07", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Agricultural and Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/10", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Technology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0702", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Animal Production", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1001", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Agricultural Biotechnology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Animal Science, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "Department of Animal Science, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Kwangwook", 
        "id": "sg:person.01224612715.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224612715.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Animal Science, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "Department of Animal Science, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "He", 
        "givenName": "Yijie", 
        "id": "sg:person.011040412656.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011040412656.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Animal Science, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "Department of Animal Science, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xiong", 
        "givenName": "Xia", 
        "id": "sg:person.0634214513.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634214513.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ehrlich", 
        "givenName": "Amy", 
        "id": "sg:person.015242313004.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015242313004.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Xunde", 
        "id": "sg:person.01277013001.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277013001.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raybould", 
        "givenName": "Helen", 
        "id": "sg:person.01311402522.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311402522.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "School of Veterinary Medicine, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Atwill", 
        "givenName": "Edward R.", 
        "id": "sg:person.01132026244.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132026244.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Animal Science, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "Department of Animal Science, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maga", 
        "givenName": "Elizabeth A.", 
        "id": "sg:person.0635723045.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635723045.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chr. Hansen A/S, Hoersholm, Denmark", 
          "id": "http://www.grid.ac/institutes/grid.424026.6", 
          "name": [
            "Chr. Hansen A/S, Hoersholm, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "J\u00f8rgensen", 
        "givenName": "Jens", 
        "id": "sg:person.015045072673.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015045072673.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Animal Science, University of California, 95616, Davis, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.27860.3b", 
          "name": [
            "Department of Animal Science, University of California, 95616, Davis, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liu", 
        "givenName": "Yanhong", 
        "id": "sg:person.01141166107.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141166107.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/2049-1891-4-52", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023308219", 
          "https://doi.org/10.1186/2049-1891-4-52"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10482-006-9067-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047071775", 
          "https://doi.org/10.1007/s10482-006-9067-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nri2653", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021427734", 
          "https://doi.org/10.1038/nri2653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13567-015-0223-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001467647", 
          "https://doi.org/10.1186/s13567-015-0223-y"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-06-25", 
    "datePublishedReg": "2019-06-25", 
    "description": "BackgroundThere is growing evidence to support the beneficial effects of supplementing direct-fed microbials (DFM) on performance, health status, and immune responses of weaned pigs. Therefore, the objective of this study was to investigate dietary supplementation of Bacillus subtilis (DSM 25841) on growth performance, diarrhea, gut permeability and immunity of weaned pigs experimentally infected with a pathogenic F-18 Escherichia coli (E. coli).ResultsThe F18 E. coli infection reduced (P\u2009<\u20090.05) growth performance and intestinal villi height, whereas increased (P\u2009<\u20090.05) diarrhea and transcellular and paracellular permeability in the jejunum compared with non-challenged control. Supplementation of Bacillus subtilis linearly enhanced average daily gain of E. coli infected pigs from d 0 to 5 post-inoculation (PI) (P\u2009<\u20090.05) and d 0 to 11 PI (P\u2009=\u20090.058). Supplementation of high dose of Bacillus subtilis reduced (P\u2009<\u20090.05) both transcellular and paracellular permeability on d 5 and d 11 PI compared with the E. coli infected pigs fed with control diet. E. coli infection up-regulated (P\u2009<\u20090.05) the mRNA expression of SLC5A10 (soluble carrier family 5 member 10) and MUC2 (mucin 2) on d 5 PI, but down-regulated (P\u2009<\u20090.05) expression of SLC5A10, MUC2, and CLDN1 on d 11 PI in jejunal mucosa when pigs were fed with the control diet. Supplementation of Bacillus subtilis linearly up-regulated (P\u2009<\u20090.05) the mRNA expression of CFTR and ZO1 on d 5 PI and SLC5A10 and MUC2 on d 11 PI in jejunal mucosa of E. coli infected pigs. In addition, E. coli infection increased (P\u2009<\u20090.05) the mRNA expression of several immune genes (IL1A, IL1B, and IL7 on d 5 PI, and IL1B, IL6, IL7, and TNF on d 11 PI) in the ileal mucosa of weaned pigs. Inclusion of Bacillus subtilis to control diet linearly down-regulated gene expression of IL1A on d 5 PI (P\u2009=\u20090.07) and IL6 on d 11 PI (P\u2009<\u20090.05) in ileal mucosa of E. coli infected pigs.ConclusionsSupplementation of Bacillus subtilis (DSM 25841) enhanced growth rate and improved gut barrier function of weaned pigs experimentally infected with a pathogenic E. coli.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s40104-019-0364-3", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1046697", 
        "issn": [
          "1674-9782", 
          "2049-1891"
        ], 
        "name": "Journal of Animal Science and Biotechnology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "keywords": [
      "E. coli infection", 
      "coli infection", 
      "mRNA expression", 
      "pathogenic E. coli", 
      "jejunal mucosa", 
      "ileal mucosa", 
      "dietary supplementation", 
      "control diet", 
      "gut barrier function", 
      "paracellular permeability", 
      "intestinal villus height", 
      "non-challenged control", 
      "gut permeability", 
      "immune response", 
      "intestinal health", 
      "high dose", 
      "villus height", 
      "health status", 
      "mucosa", 
      "growth performance", 
      "beneficial effects", 
      "barrier function", 
      "supplementation", 
      "infection", 
      "MUC2", 
      "immune genes", 
      "E. coli", 
      "weaned pigs", 
      "diarrhea", 
      "average daily gain", 
      "diet", 
      "pigs", 
      "expression", 
      "daily gain", 
      "gene expression", 
      "ConclusionsSupplementation", 
      "IL6", 
      "BackgroundThere", 
      "jejunum", 
      "IL1A", 
      "dose", 
      "immunity", 
      "CLDN1", 
      "SLC5A10", 
      "ZO1", 
      "health", 
      "transcellular", 
      "status", 
      "coli", 
      "Escherichia coli", 
      "PI", 
      "CFTR", 
      "response", 
      "evidence", 
      "permeability", 
      "control", 
      "study", 
      "genes", 
      "rate", 
      "effect", 
      "objective", 
      "function", 
      "addition", 
      "inclusion", 
      "Bacillus subtilis", 
      "gain", 
      "Microbial", 
      "height", 
      "growth rate", 
      "subtilis", 
      "performance"
    ], 
    "name": "Dietary supplementation of Bacillus subtilis influenced intestinal health of weaned pigs experimentally infected with a pathogenic E. coli", 
    "pagination": "52", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1117485716"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s40104-019-0364-3"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s40104-019-0364-3", 
      "https://app.dimensions.ai/details/publication/pub.1117485716"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_823.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s40104-019-0364-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s40104-019-0364-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s40104-019-0364-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s40104-019-0364-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s40104-019-0364-3'


 

This table displays all metadata directly associated to this object as RDF triples.

220 TRIPLES      21 PREDICATES      101 URIs      87 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s40104-019-0364-3 schema:about anzsrc-for:07
2 anzsrc-for:0702
3 anzsrc-for:10
4 anzsrc-for:1001
5 schema:author N8e24859ac9ee444bb14e93c963f2f0e8
6 schema:citation sg:pub.10.1007/s10482-006-9067-9
7 sg:pub.10.1038/nri2653
8 sg:pub.10.1186/2049-1891-4-52
9 sg:pub.10.1186/s13567-015-0223-y
10 schema:datePublished 2019-06-25
11 schema:datePublishedReg 2019-06-25
12 schema:description BackgroundThere is growing evidence to support the beneficial effects of supplementing direct-fed microbials (DFM) on performance, health status, and immune responses of weaned pigs. Therefore, the objective of this study was to investigate dietary supplementation of Bacillus subtilis (DSM 25841) on growth performance, diarrhea, gut permeability and immunity of weaned pigs experimentally infected with a pathogenic F-18 Escherichia coli (E. coli).ResultsThe F18 E. coli infection reduced (P < 0.05) growth performance and intestinal villi height, whereas increased (P < 0.05) diarrhea and transcellular and paracellular permeability in the jejunum compared with non-challenged control. Supplementation of Bacillus subtilis linearly enhanced average daily gain of E. coli infected pigs from d 0 to 5 post-inoculation (PI) (P < 0.05) and d 0 to 11 PI (P = 0.058). Supplementation of high dose of Bacillus subtilis reduced (P < 0.05) both transcellular and paracellular permeability on d 5 and d 11 PI compared with the E. coli infected pigs fed with control diet. E. coli infection up-regulated (P < 0.05) the mRNA expression of SLC5A10 (soluble carrier family 5 member 10) and MUC2 (mucin 2) on d 5 PI, but down-regulated (P < 0.05) expression of SLC5A10, MUC2, and CLDN1 on d 11 PI in jejunal mucosa when pigs were fed with the control diet. Supplementation of Bacillus subtilis linearly up-regulated (P < 0.05) the mRNA expression of CFTR and ZO1 on d 5 PI and SLC5A10 and MUC2 on d 11 PI in jejunal mucosa of E. coli infected pigs. In addition, E. coli infection increased (P < 0.05) the mRNA expression of several immune genes (IL1A, IL1B, and IL7 on d 5 PI, and IL1B, IL6, IL7, and TNF on d 11 PI) in the ileal mucosa of weaned pigs. Inclusion of Bacillus subtilis to control diet linearly down-regulated gene expression of IL1A on d 5 PI (P = 0.07) and IL6 on d 11 PI (P < 0.05) in ileal mucosa of E. coli infected pigs.ConclusionsSupplementation of Bacillus subtilis (DSM 25841) enhanced growth rate and improved gut barrier function of weaned pigs experimentally infected with a pathogenic E. coli.
13 schema:genre article
14 schema:isAccessibleForFree true
15 schema:isPartOf N0be76f6990a24655808bfeee316092e4
16 N7f9ae46e470645a1831f2ae670df7a97
17 sg:journal.1046697
18 schema:keywords Bacillus subtilis
19 BackgroundThere
20 CFTR
21 CLDN1
22 ConclusionsSupplementation
23 E. coli
24 E. coli infection
25 Escherichia coli
26 IL1A
27 IL6
28 MUC2
29 Microbial
30 PI
31 SLC5A10
32 ZO1
33 addition
34 average daily gain
35 barrier function
36 beneficial effects
37 coli
38 coli infection
39 control
40 control diet
41 daily gain
42 diarrhea
43 diet
44 dietary supplementation
45 dose
46 effect
47 evidence
48 expression
49 function
50 gain
51 gene expression
52 genes
53 growth performance
54 growth rate
55 gut barrier function
56 gut permeability
57 health
58 health status
59 height
60 high dose
61 ileal mucosa
62 immune genes
63 immune response
64 immunity
65 inclusion
66 infection
67 intestinal health
68 intestinal villus height
69 jejunal mucosa
70 jejunum
71 mRNA expression
72 mucosa
73 non-challenged control
74 objective
75 paracellular permeability
76 pathogenic E. coli
77 performance
78 permeability
79 pigs
80 rate
81 response
82 status
83 study
84 subtilis
85 supplementation
86 transcellular
87 villus height
88 weaned pigs
89 schema:name Dietary supplementation of Bacillus subtilis influenced intestinal health of weaned pigs experimentally infected with a pathogenic E. coli
90 schema:pagination 52
91 schema:productId N5e34f3ea71c04266afb86a589589f025
92 Nc5f0a4ebb23b4e8db76aa9a88ae8d542
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1117485716
94 https://doi.org/10.1186/s40104-019-0364-3
95 schema:sdDatePublished 2022-12-01T06:40
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher N6c6b3d283bcb452894b2207d0e9f35f3
98 schema:url https://doi.org/10.1186/s40104-019-0364-3
99 sgo:license sg:explorer/license/
100 sgo:sdDataset articles
101 rdf:type schema:ScholarlyArticle
102 N019ede6c350340c28aa5315da83deab7 rdf:first sg:person.01132026244.65
103 rdf:rest Ne145c86398794ab48871ca6ff942004f
104 N06cacaefbdb1418cb577e8b6bedc50ca rdf:first sg:person.015045072673.03
105 rdf:rest N6438bc31ef4847c4bb47a498f4918a8f
106 N0be76f6990a24655808bfeee316092e4 schema:volumeNumber 10
107 rdf:type schema:PublicationVolume
108 N1e9ee6ad916d4d62b0d499d6c5fbd074 rdf:first sg:person.011040412656.30
109 rdf:rest N1eed235793c64defa324dd4d4b44a29f
110 N1eed235793c64defa324dd4d4b44a29f rdf:first sg:person.0634214513.93
111 rdf:rest N59d14a114f2343f4a753e9d3bf1bbeab
112 N59d14a114f2343f4a753e9d3bf1bbeab rdf:first sg:person.015242313004.79
113 rdf:rest N6ade71aa605e4c01ad66213b080be212
114 N5e34f3ea71c04266afb86a589589f025 schema:name doi
115 schema:value 10.1186/s40104-019-0364-3
116 rdf:type schema:PropertyValue
117 N6438bc31ef4847c4bb47a498f4918a8f rdf:first sg:person.01141166107.45
118 rdf:rest rdf:nil
119 N6ade71aa605e4c01ad66213b080be212 rdf:first sg:person.01277013001.83
120 rdf:rest N8010a28b952f49faaf0e07858ae9abf1
121 N6c6b3d283bcb452894b2207d0e9f35f3 schema:name Springer Nature - SN SciGraph project
122 rdf:type schema:Organization
123 N7f9ae46e470645a1831f2ae670df7a97 schema:issueNumber 1
124 rdf:type schema:PublicationIssue
125 N8010a28b952f49faaf0e07858ae9abf1 rdf:first sg:person.01311402522.25
126 rdf:rest N019ede6c350340c28aa5315da83deab7
127 N8e24859ac9ee444bb14e93c963f2f0e8 rdf:first sg:person.01224612715.86
128 rdf:rest N1e9ee6ad916d4d62b0d499d6c5fbd074
129 Nc5f0a4ebb23b4e8db76aa9a88ae8d542 schema:name dimensions_id
130 schema:value pub.1117485716
131 rdf:type schema:PropertyValue
132 Ne145c86398794ab48871ca6ff942004f rdf:first sg:person.0635723045.39
133 rdf:rest N06cacaefbdb1418cb577e8b6bedc50ca
134 anzsrc-for:07 schema:inDefinedTermSet anzsrc-for:
135 schema:name Agricultural and Veterinary Sciences
136 rdf:type schema:DefinedTerm
137 anzsrc-for:0702 schema:inDefinedTermSet anzsrc-for:
138 schema:name Animal Production
139 rdf:type schema:DefinedTerm
140 anzsrc-for:10 schema:inDefinedTermSet anzsrc-for:
141 schema:name Technology
142 rdf:type schema:DefinedTerm
143 anzsrc-for:1001 schema:inDefinedTermSet anzsrc-for:
144 schema:name Agricultural Biotechnology
145 rdf:type schema:DefinedTerm
146 sg:journal.1046697 schema:issn 1674-9782
147 2049-1891
148 schema:name Journal of Animal Science and Biotechnology
149 schema:publisher Springer Nature
150 rdf:type schema:Periodical
151 sg:person.011040412656.30 schema:affiliation grid-institutes:grid.27860.3b
152 schema:familyName He
153 schema:givenName Yijie
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011040412656.30
155 rdf:type schema:Person
156 sg:person.01132026244.65 schema:affiliation grid-institutes:grid.27860.3b
157 schema:familyName Atwill
158 schema:givenName Edward R.
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132026244.65
160 rdf:type schema:Person
161 sg:person.01141166107.45 schema:affiliation grid-institutes:grid.27860.3b
162 schema:familyName Liu
163 schema:givenName Yanhong
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141166107.45
165 rdf:type schema:Person
166 sg:person.01224612715.86 schema:affiliation grid-institutes:grid.27860.3b
167 schema:familyName Kim
168 schema:givenName Kwangwook
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224612715.86
170 rdf:type schema:Person
171 sg:person.01277013001.83 schema:affiliation grid-institutes:grid.27860.3b
172 schema:familyName Li
173 schema:givenName Xunde
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277013001.83
175 rdf:type schema:Person
176 sg:person.01311402522.25 schema:affiliation grid-institutes:grid.27860.3b
177 schema:familyName Raybould
178 schema:givenName Helen
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311402522.25
180 rdf:type schema:Person
181 sg:person.015045072673.03 schema:affiliation grid-institutes:grid.424026.6
182 schema:familyName Jørgensen
183 schema:givenName Jens
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015045072673.03
185 rdf:type schema:Person
186 sg:person.015242313004.79 schema:affiliation grid-institutes:grid.27860.3b
187 schema:familyName Ehrlich
188 schema:givenName Amy
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015242313004.79
190 rdf:type schema:Person
191 sg:person.0634214513.93 schema:affiliation grid-institutes:grid.27860.3b
192 schema:familyName Xiong
193 schema:givenName Xia
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634214513.93
195 rdf:type schema:Person
196 sg:person.0635723045.39 schema:affiliation grid-institutes:grid.27860.3b
197 schema:familyName Maga
198 schema:givenName Elizabeth A.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635723045.39
200 rdf:type schema:Person
201 sg:pub.10.1007/s10482-006-9067-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047071775
202 https://doi.org/10.1007/s10482-006-9067-9
203 rdf:type schema:CreativeWork
204 sg:pub.10.1038/nri2653 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021427734
205 https://doi.org/10.1038/nri2653
206 rdf:type schema:CreativeWork
207 sg:pub.10.1186/2049-1891-4-52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023308219
208 https://doi.org/10.1186/2049-1891-4-52
209 rdf:type schema:CreativeWork
210 sg:pub.10.1186/s13567-015-0223-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1001467647
211 https://doi.org/10.1186/s13567-015-0223-y
212 rdf:type schema:CreativeWork
213 grid-institutes:grid.27860.3b schema:alternateName Department of Animal Science, University of California, 95616, Davis, CA, USA
214 School of Veterinary Medicine, University of California, 95616, Davis, CA, USA
215 schema:name Department of Animal Science, University of California, 95616, Davis, CA, USA
216 School of Veterinary Medicine, University of California, 95616, Davis, CA, USA
217 rdf:type schema:Organization
218 grid-institutes:grid.424026.6 schema:alternateName Chr. Hansen A/S, Hoersholm, Denmark
219 schema:name Chr. Hansen A/S, Hoersholm, Denmark
220 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...