Enhancement of arterial pulsation during flow-mediated dilation is impaired in the presence of ischemic heart disease View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Eisuke Amiya, Masafumi Watanabe, Shogo Watanabe, Munenori Takata, Issei Komuro

ABSTRACT

PURPOSE: The aim of this study is to investigate the relationship between arterial pulse amplitude change under increased shear stress and the presence of ischemic heart disease (IHD). METHODS: This study comprised 31 subjects, including 14 subjects with IHD. We investigated the change in brachial artery pulse amplitude during flow-mediated dilation (FMD) using ultrasonography. RESULTS: The arterial pulse amplitude increased during FMD in 19 subjects, whereas it decreased in 12 subjects. There was a marked difference in the change in arterial pulse amplitude (the maximum amplitude of the arterial pulse amplitude during FMD/the arterial pulse amplitude at baseline) between subjects with and without IHD (0.98 ± 0.53 and 1.37 ± 0.53, p = 0.028). Furthermore, decreased arterial pulse amplitude during FMD was a significant predictor of IHD after adjustment of age, blood pressure, the presence of each type of coronary risks, the value of FMD and sex (p = 0.0001). CONCLUSIONS: The decrease of arterial pulsation amplitude during FMD was a useful predictive parameter for IHD. More... »

PAGES

1103

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URI

http://scigraph.springernature.com/pub.10.1186/s40064-016-2794-0

DOI

http://dx.doi.org/10.1186/s40064-016-2794-0

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https://app.dimensions.ai/details/publication/pub.1003865841

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27468404


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