Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Elif Diken, Tugba Ozer, Muzaffer Arikan, Zeliha Emrence, Ebru Toksoy Oner, Duran Ustek, Kazim Yalcin Arga

ABSTRACT

Halomonas smyrnensis AAD6T is a gram negative, aerobic, and moderately halophilic bacterium, and is known to produce high levels of levan with many potential uses in foods, feeds, cosmetics, pharmaceutical and chemical industries due to its outstanding properties. Here, the whole-genome analysis was performed to gain more insight about the biological mechanisms, and the whole-genome organization of the bacterium. Industrially crucial genes, including the levansucrase, were detected and the genome-scale metabolic model of H. smyrnensis AAD6T was reconstructed. The bacterium was found to have many potential applications in biotechnology not only being a levan producer, but also because of its capacity to produce Pel exopolysaccharide, polyhydroxyalkanoates, and osmoprotectants. The genomic information presented here will not only provide additional information to enhance our understanding of the genetic and metabolic network of halophilic bacteria, but also accelerate the research on systematical design of engineering strategies for biotechnology applications. More... »

PAGES

393

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40064-015-1184-3

DOI

http://dx.doi.org/10.1186/s40064-015-1184-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000331233

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26251777


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