Treatment strategies for treatment naïve HIV patients in Germany: evidence from claims data View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Jörg Mahlich, Johannes R Bogner, Jörg Tomeczkowski, Matthias Stoll

ABSTRACT

A recent observational study of HIV patients in Germany suggests that treatment naïve patients that are in a more advanced stage of their disease are more likely to receive a treatment regimen based on a boosted protease inhibitor (PI/r) compared with a non-nucleoside reverse-transcriptase-inhibitor (NNRTI) base regimen. To validate those results we analysed claims data of seven German sickness funds from 2009 to 2012 with approximately 4 million beneficiaries. Patients in a more advanced disease state (CDC class C) had a higher likelihood to receive a PI/r based regime rather than a NNRTI based regimen as their initial treatment. There was also a significant correlation between PI/r based regimen and number of comorbidities but not with age. Our results confirm a highly significant relationship between being in a more severe stage of HIV disease and a PI/r based treatment regimen. More... »

PAGES

306

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s40064-015-1099-z

DOI

http://dx.doi.org/10.1186/s40064-015-1099-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013754500

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26155445


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