Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Jesse Elliott, Bláthnaid McCoy, Tammy Clifford, Beth K. Potter, Becky Skidmore, George A. Wells, Doug Coyle

ABSTRACT

BACKGROUND: Drug-resistant epilepsy negatively impacts the quality of life and is associated with increased morbidity and mortality and high costs to the healthcare system. Cannabis-based treatments may be effective in reducing seizures in this population, but whether they are cost-effective is unclear. In this systematic review, we will search for cost-effectiveness analyses involving the treatment of pediatric drug-resistant epilepsy with cannabis-based products to inform decision-making by public healthcare payers about reimbursement of such products. We will also search for cost-effectiveness analyses of other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as estimates of healthcare resource use, costs, and utilities, for use in a subsequent cost-utility analysis to address this decision problem. METHODS: We will search the published and gray literature for economic evaluations of cannabis-based products and other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as resource utilization and utility studies. Two independent reviewers will screen the title and abstract of each identified record and the full-text version of any study deemed potentially relevant. Study and population characteristics, the incremental cost-effectiveness ratio (ICER), as well as total costs and benefits, will be extracted, and quality will be assessed by use of the Drummond and CHEERS checklists; context-specific issues will also be considered. From model-based cost-utility and cost-effectiveness analyses, we will extract and summarize the model structure, including health states, time horizon, and cycle length. From resource utilization studies, we will extract data about the frequency of resource use (e.g., neurology visits, emergency department visits, admissions to hospital). From utility studies, we will extract the utility for each health state, the source of the preferences (e.g., child, parent, patient, general public), and the method of elicitation. DISCUSSION: Drug-resistant epilepsy in children is associated with important costs to the healthcare system, and decision-makers require high-quality evidence on which to base reimbursement decisions. The results of this review will be useful to both decision-makers considering the decision problem of whether to reimburse cannabis-based products through public formularies and to analysts conducting studies in this area. SYSTEMATIC REVIEW REGISTRATION: PROSPERO no.: CRD42018099591 . More... »

PAGES

75

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13643-019-0990-z

DOI

http://dx.doi.org/10.1186/s13643-019-0990-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113046901

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30917869


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada", 
            "Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y4W7, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Elliott", 
        "givenName": "Jesse", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Department of Paediatrics, University of Toronto, Division of Neurology, The Hospital for Sick Children Toronto, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McCoy", 
        "givenName": "Bl\u00e1thnaid", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Clifford", 
        "givenName": "Tammy", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Potter", 
        "givenName": "Beth K.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Independent Information Specialist, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Skidmore", 
        "givenName": "Becky", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada", 
            "Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y4W7, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wells", 
        "givenName": "George A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coyle", 
        "givenName": "Doug", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.ejpn.2015.11.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005707503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0161660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009332575"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1528-1167.2009.02397.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016039244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1528-1167.2009.02397.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016039244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/2046-4053-4-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024252988", 
          "https://doi.org/10.1186/2046-4053-4-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/epi.13084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029583592"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yebeh.2014.01.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033597106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1528-1167.2007.01466.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037162344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jval.2013.02.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043414883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2016.01.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044077314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/epi.13003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048798629"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/epi.12633", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048907064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1528-1157.1998.tb01164.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049192842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1528-1157.1998.tb01164.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049192842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrneurol.2014.58", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051521517", 
          "https://doi.org/10.1038/nrneurol.2014.58"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yebeh.2016.11.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083747938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1611618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085588632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(18)30136-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100648886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(18)30136-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100648886"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Drug-resistant epilepsy negatively impacts the quality of life and is associated with increased morbidity and mortality and high costs to the healthcare system. Cannabis-based treatments may be effective in reducing seizures in this population, but whether they are cost-effective is unclear. In this systematic review, we will search for cost-effectiveness analyses involving the treatment of pediatric drug-resistant epilepsy with cannabis-based products to inform decision-making by public healthcare payers about reimbursement of such products. We will also search for cost-effectiveness analyses of other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as estimates of healthcare resource use, costs, and utilities, for use in a subsequent cost-utility analysis to address this decision problem.\nMETHODS: We will search the published and gray literature for economic evaluations of cannabis-based products and other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as resource utilization and utility studies. Two independent reviewers will screen the title and abstract of each identified record and the full-text version of any study deemed potentially relevant. Study and population characteristics, the incremental cost-effectiveness ratio (ICER), as well as total costs and benefits, will be extracted, and quality will be assessed by use of the Drummond and CHEERS checklists; context-specific issues will also be considered. From model-based cost-utility and cost-effectiveness analyses, we will extract and summarize the model structure, including health states, time horizon, and cycle length. From resource utilization studies, we will extract data about the frequency of resource use (e.g., neurology visits, emergency department visits, admissions to hospital). From utility studies, we will extract the utility for each health state, the source of the preferences (e.g., child, parent, patient, general public), and the method of elicitation.\nDISCUSSION: Drug-resistant epilepsy in children is associated with important costs to the healthcare system, and decision-makers require high-quality evidence on which to base reimbursement decisions. The results of this review will be useful to both decision-makers considering the decision problem of whether to reimburse cannabis-based products through public formularies and to analysts conducting studies in this area.\nSYSTEMATIC REVIEW REGISTRATION: PROSPERO no.: CRD42018099591 .", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s13643-019-0990-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1046628", 
        "issn": [
          "2046-4053"
        ], 
        "name": "Systematic Reviews", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations", 
    "pagination": "75", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13643-019-0990-z"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b1d697976b78d203f9871fe7648881628bd2b72a77fcfee6911d0bfe32909a6f"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113046901"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101580575"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30917869"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13643-019-0990-z", 
      "https://app.dimensions.ai/details/publication/pub.1113046901"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119717_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs13643-019-0990-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13643-019-0990-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13643-019-0990-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13643-019-0990-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13643-019-0990-z'


 

This table displays all metadata directly associated to this object as RDF triples.

159 TRIPLES      21 PREDICATES      45 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13643-019-0990-z schema:about anzsrc-for:11
2 anzsrc-for:1117
3 schema:author Nbb5fc360c42a4d8e89669e3de1bca3c4
4 schema:citation sg:pub.10.1038/nrneurol.2014.58
5 sg:pub.10.1186/2046-4053-4-1
6 https://doi.org/10.1016/j.ejpn.2015.11.003
7 https://doi.org/10.1016/j.jclinepi.2016.01.021
8 https://doi.org/10.1016/j.jval.2013.02.010
9 https://doi.org/10.1016/j.yebeh.2014.01.016
10 https://doi.org/10.1016/j.yebeh.2016.11.012
11 https://doi.org/10.1016/s0140-6736(18)30136-3
12 https://doi.org/10.1056/nejmoa1611618
13 https://doi.org/10.1111/epi.12633
14 https://doi.org/10.1111/epi.13003
15 https://doi.org/10.1111/epi.13084
16 https://doi.org/10.1111/j.1528-1157.1998.tb01164.x
17 https://doi.org/10.1111/j.1528-1167.2007.01466.x
18 https://doi.org/10.1111/j.1528-1167.2009.02397.x
19 https://doi.org/10.1371/journal.pone.0161660
20 schema:datePublished 2019-12
21 schema:datePublishedReg 2019-12-01
22 schema:description BACKGROUND: Drug-resistant epilepsy negatively impacts the quality of life and is associated with increased morbidity and mortality and high costs to the healthcare system. Cannabis-based treatments may be effective in reducing seizures in this population, but whether they are cost-effective is unclear. In this systematic review, we will search for cost-effectiveness analyses involving the treatment of pediatric drug-resistant epilepsy with cannabis-based products to inform decision-making by public healthcare payers about reimbursement of such products. We will also search for cost-effectiveness analyses of other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as estimates of healthcare resource use, costs, and utilities, for use in a subsequent cost-utility analysis to address this decision problem. METHODS: We will search the published and gray literature for economic evaluations of cannabis-based products and other pharmacologic treatments for pediatric drug-resistant epilepsy, as well as resource utilization and utility studies. Two independent reviewers will screen the title and abstract of each identified record and the full-text version of any study deemed potentially relevant. Study and population characteristics, the incremental cost-effectiveness ratio (ICER), as well as total costs and benefits, will be extracted, and quality will be assessed by use of the Drummond and CHEERS checklists; context-specific issues will also be considered. From model-based cost-utility and cost-effectiveness analyses, we will extract and summarize the model structure, including health states, time horizon, and cycle length. From resource utilization studies, we will extract data about the frequency of resource use (e.g., neurology visits, emergency department visits, admissions to hospital). From utility studies, we will extract the utility for each health state, the source of the preferences (e.g., child, parent, patient, general public), and the method of elicitation. DISCUSSION: Drug-resistant epilepsy in children is associated with important costs to the healthcare system, and decision-makers require high-quality evidence on which to base reimbursement decisions. The results of this review will be useful to both decision-makers considering the decision problem of whether to reimburse cannabis-based products through public formularies and to analysts conducting studies in this area. SYSTEMATIC REVIEW REGISTRATION: PROSPERO no.: CRD42018099591 .
23 schema:genre research_article
24 schema:inLanguage en
25 schema:isAccessibleForFree true
26 schema:isPartOf Naef05d98549e43be921a1b66a179049b
27 Nc07b8a784e344ccd896f00f7d1709849
28 sg:journal.1046628
29 schema:name Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations
30 schema:pagination 75
31 schema:productId N22f4bb8b731043819562fe0a18861c40
32 N28cee3d97a77498e8f156aac3b63820f
33 N748d80e2cda740c1b5fac371931f749b
34 Ndadda6e509534bc18f5ec976f49f5501
35 Nf170bfbc171c4c14abc96faeb5dc9968
36 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113046901
37 https://doi.org/10.1186/s13643-019-0990-z
38 schema:sdDatePublished 2019-04-15T08:48
39 schema:sdLicense https://scigraph.springernature.com/explorer/license/
40 schema:sdPublisher Nedd0217dd8e44ac4a14abb3820db8196
41 schema:url https://link.springer.com/10.1186%2Fs13643-019-0990-z
42 sgo:license sg:explorer/license/
43 sgo:sdDataset articles
44 rdf:type schema:ScholarlyArticle
45 N0d53f770a6c2448dba228e8aabd05317 rdf:first N4a89b8eedefc43328c2cf5c4e8e07678
46 rdf:rest Na262eaa134254c1c9a588639898004af
47 N22f4bb8b731043819562fe0a18861c40 schema:name pubmed_id
48 schema:value 30917869
49 rdf:type schema:PropertyValue
50 N277889a7f1c0494aa55a8363e23cde6e schema:affiliation https://www.grid.ac/institutes/grid.28046.38
51 schema:familyName Elliott
52 schema:givenName Jesse
53 rdf:type schema:Person
54 N28cee3d97a77498e8f156aac3b63820f schema:name dimensions_id
55 schema:value pub.1113046901
56 rdf:type schema:PropertyValue
57 N3583c1ea8dbd4c4b8b49a9946f866a46 rdf:first N88f02c7fa8ef450fa3f8dfaa8a9afccc
58 rdf:rest N0d53f770a6c2448dba228e8aabd05317
59 N4a89b8eedefc43328c2cf5c4e8e07678 schema:affiliation Na13d6dbd7eba44bd87888280ff39b002
60 schema:familyName Skidmore
61 schema:givenName Becky
62 rdf:type schema:Person
63 N748d80e2cda740c1b5fac371931f749b schema:name doi
64 schema:value 10.1186/s13643-019-0990-z
65 rdf:type schema:PropertyValue
66 N7e8eea4bf99e4e6ea48c440c3adc272f rdf:first Nc914b69bff8d4085bd52b70d96193582
67 rdf:rest Nee218e9ee8034514a43c414283f55613
68 N88f02c7fa8ef450fa3f8dfaa8a9afccc schema:affiliation https://www.grid.ac/institutes/grid.28046.38
69 schema:familyName Potter
70 schema:givenName Beth K.
71 rdf:type schema:Person
72 N93067d3d003b49e088b26b14ff7006c4 rdf:first Naa546f1462a2478e8b34291d6bef5b8f
73 rdf:rest rdf:nil
74 N9db9f06636d847b6afc32f6a5e6a06e9 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
75 schema:familyName Clifford
76 schema:givenName Tammy
77 rdf:type schema:Person
78 Na13d6dbd7eba44bd87888280ff39b002 schema:name Independent Information Specialist, Ottawa, Canada
79 rdf:type schema:Organization
80 Na262eaa134254c1c9a588639898004af rdf:first Nacc36c29c24948f8aa024c30508d8da7
81 rdf:rest N93067d3d003b49e088b26b14ff7006c4
82 Naa546f1462a2478e8b34291d6bef5b8f schema:affiliation https://www.grid.ac/institutes/grid.28046.38
83 schema:familyName Coyle
84 schema:givenName Doug
85 rdf:type schema:Person
86 Nacc36c29c24948f8aa024c30508d8da7 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
87 schema:familyName Wells
88 schema:givenName George A.
89 rdf:type schema:Person
90 Naef05d98549e43be921a1b66a179049b schema:issueNumber 1
91 rdf:type schema:PublicationIssue
92 Nbb5fc360c42a4d8e89669e3de1bca3c4 rdf:first N277889a7f1c0494aa55a8363e23cde6e
93 rdf:rest N7e8eea4bf99e4e6ea48c440c3adc272f
94 Nc07b8a784e344ccd896f00f7d1709849 schema:volumeNumber 8
95 rdf:type schema:PublicationVolume
96 Nc914b69bff8d4085bd52b70d96193582 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
97 schema:familyName McCoy
98 schema:givenName Bláthnaid
99 rdf:type schema:Person
100 Ndadda6e509534bc18f5ec976f49f5501 schema:name readcube_id
101 schema:value b1d697976b78d203f9871fe7648881628bd2b72a77fcfee6911d0bfe32909a6f
102 rdf:type schema:PropertyValue
103 Nedd0217dd8e44ac4a14abb3820db8196 schema:name Springer Nature - SN SciGraph project
104 rdf:type schema:Organization
105 Nee218e9ee8034514a43c414283f55613 rdf:first N9db9f06636d847b6afc32f6a5e6a06e9
106 rdf:rest N3583c1ea8dbd4c4b8b49a9946f866a46
107 Nf170bfbc171c4c14abc96faeb5dc9968 schema:name nlm_unique_id
108 schema:value 101580575
109 rdf:type schema:PropertyValue
110 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
111 schema:name Medical and Health Sciences
112 rdf:type schema:DefinedTerm
113 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
114 schema:name Public Health and Health Services
115 rdf:type schema:DefinedTerm
116 sg:journal.1046628 schema:issn 2046-4053
117 schema:name Systematic Reviews
118 rdf:type schema:Periodical
119 sg:pub.10.1038/nrneurol.2014.58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051521517
120 https://doi.org/10.1038/nrneurol.2014.58
121 rdf:type schema:CreativeWork
122 sg:pub.10.1186/2046-4053-4-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024252988
123 https://doi.org/10.1186/2046-4053-4-1
124 rdf:type schema:CreativeWork
125 https://doi.org/10.1016/j.ejpn.2015.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005707503
126 rdf:type schema:CreativeWork
127 https://doi.org/10.1016/j.jclinepi.2016.01.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044077314
128 rdf:type schema:CreativeWork
129 https://doi.org/10.1016/j.jval.2013.02.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043414883
130 rdf:type schema:CreativeWork
131 https://doi.org/10.1016/j.yebeh.2014.01.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033597106
132 rdf:type schema:CreativeWork
133 https://doi.org/10.1016/j.yebeh.2016.11.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083747938
134 rdf:type schema:CreativeWork
135 https://doi.org/10.1016/s0140-6736(18)30136-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100648886
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1056/nejmoa1611618 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085588632
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1111/epi.12633 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048907064
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1111/epi.13003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048798629
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1111/epi.13084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029583592
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1111/j.1528-1157.1998.tb01164.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049192842
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1111/j.1528-1167.2007.01466.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037162344
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1111/j.1528-1167.2009.02397.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016039244
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1371/journal.pone.0161660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009332575
152 rdf:type schema:CreativeWork
153 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
154 schema:name Department of Paediatrics, University of Toronto, Division of Neurology, The Hospital for Sick Children Toronto, Toronto, Ontario, Canada
155 rdf:type schema:Organization
156 https://www.grid.ac/institutes/grid.28046.38 schema:alternateName University of Ottawa
157 schema:name Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, K1Y4W7, Ottawa, Canada
158 School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, K1G 5Z3, Ottawa, Canada
159 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...