Severe but reversible impaired diaphragm function in septic mechanically ventilated patients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-04-11

AUTHORS

Marie Lecronier, Boris Jung, Nicolas Molinari, Jérôme Pinot, Thomas Similowski, Samir Jaber, Alexandre Demoule, Martin Dres

ABSTRACT

BackgroundWhether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time course of septic and non-septic mechanically ventilated patients.MethodsSecondary analysis of two prospective observational studies of mechanically ventilated patients in whom diaphragm function was assessed twice: within the 24 h after intubation and when patients were switched to pressure support mode, by measuring the endotracheal pressure in response to bilateral anterior magnetic phrenic nerve stimulation (Ptr,stim). Change in diaphragm function was expressed as the difference between Ptr,stim measured under pressure support mode and Ptr,stim measured within the 24 h after intubation. Sepsis was defined according to the Sepsis-3 international guidelines upon inclusion. In a sub-group of patients, the right hemidiaphragm thickness was measured by ultrasound.ResultsNinety-two patients were enrolled in the study. Sepsis upon intubation was present in 51 (55%) patients. In septic patients, primary reason for ventilation was acute respiratory failure related to pneumonia (37/51; 73%). In non-septic patients, main reasons for ventilation were acute respiratory failure not related to pneumonia (16/41; 39%), coma (13/41; 32%) and cardiac arrest (6/41; 15%). Ptr,stim within 24 h after intubation was lower in septic patients as compared to non-septic patients: 6.3 (4.9–8.7) cmH2O vs. 9.8 (7.0–14.2) cmH2O (p = 0.004), respectively. The median (interquartile) duration of mechanical ventilation between first and second diaphragm evaluation was 4 (2–6) days in septic patients and 3 (2–4) days in non-septic patients (p = 0.073). Between first and second measurements, the change in Ptr,stim was + 19% (− 13–61) in septic patients and − 7% (− 40–12) in non-septic patients (p = 0.005). In the sub-group of patients with ultrasound measurements, end-expiratory diaphragm thickness decreased in both, septic and non-septic patients. The 28-day mortality was higher in patients with decrease or no change in diaphragm function.ConclusionSeptic patients were associated with a more severe but reversible impaired diaphragm function as compared to non-septic patients. Increase in diaphragm function was associated with a better survival. More... »

PAGES

34

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13613-022-01005-9

DOI

http://dx.doi.org/10.1186/s13613-022-01005-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1146979467

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35403916


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1116", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Physiology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.462844.8", 
          "name": [
            "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France", 
            "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lecronier", 
        "givenName": "Marie", 
        "id": "sg:person.01362670477.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362670477.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratoire de Physiologie et M\u00e9decine Exp\u00e9rimentale du c\u0153ur et des Muscles, INSERM U1046-CNRS UMR 9214, Universit\u00e9 de Montpellier, Montpellier, France", 
          "id": "http://www.grid.ac/institutes/grid.121334.6", 
          "name": [
            "D\u00e9partement de M\u00e9decine Intensive - R\u00e9animation, CHU Montpellier, Montpellier, France", 
            "Laboratoire de Physiologie et M\u00e9decine Exp\u00e9rimentale du c\u0153ur et des Muscles, INSERM U1046-CNRS UMR 9214, Universit\u00e9 de Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jung", 
        "givenName": "Boris", 
        "id": "sg:person.01230435413.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230435413.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Information, H\u00f4pital Arnaud de Villeneuve, IMAG U5149, Universit\u00e9 de Montpellier, Montpellier, France", 
          "id": "http://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Department of Medical Information, H\u00f4pital Arnaud de Villeneuve, IMAG U5149, Universit\u00e9 de Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Molinari", 
        "givenName": "Nicolas", 
        "id": "sg:person.01266343767.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266343767.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.411439.a", 
          "name": [
            "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pinot", 
        "givenName": "J\u00e9r\u00f4me", 
        "id": "sg:person.012402413440.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012402413440.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.462844.8", 
          "name": [
            "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France", 
            "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Similowski", 
        "givenName": "Thomas", 
        "id": "sg:person.01235111105.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235111105.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratoire de Physiologie et M\u00e9decine Exp\u00e9rimentale du c\u0153ur et des Muscles, INSERM U1046-CNRS UMR 9214, Universit\u00e9 de Montpellier, Montpellier, France", 
          "id": "http://www.grid.ac/institutes/grid.121334.6", 
          "name": [
            "D\u00e9partement de M\u00e9decine Intensive - R\u00e9animation, CHU Montpellier, Montpellier, France", 
            "Laboratoire de Physiologie et M\u00e9decine Exp\u00e9rimentale du c\u0153ur et des Muscles, INSERM U1046-CNRS UMR 9214, Universit\u00e9 de Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jaber", 
        "givenName": "Samir", 
        "id": "sg:person.01113242353.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113242353.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.462844.8", 
          "name": [
            "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France", 
            "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Demoule", 
        "givenName": "Alexandre", 
        "id": "sg:person.0673253666.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673253666.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.462844.8", 
          "name": [
            "M\u00e9decine Intensive - R\u00e9animation (D\u00e9partement \u201cR3S\u201d), APHP. Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France", 
            "Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique, INSERM-UMR S 1158, Sorbonne Universit\u00e9, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dres", 
        "givenName": "Martin", 
        "id": "sg:person.01120203457.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120203457.34"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/cc10023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037336704", 
          "https://doi.org/10.1186/cc10023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-017-4928-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091765651", 
          "https://doi.org/10.1007/s00134-017-4928-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-010-9176-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028599545", 
          "https://doi.org/10.1007/s10741-010-9176-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc9094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024386586", 
          "https://doi.org/10.1186/cc9094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-018-1992-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101629732", 
          "https://doi.org/10.1186/s13054-018-1992-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-019-05892-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1124076869", 
          "https://doi.org/10.1007/s00134-019-05892-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc12864", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037241624", 
          "https://doi.org/10.1186/cc12864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-020-03338-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1132948548", 
          "https://doi.org/10.1186/s13054-020-03338-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13613-016-0179-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026819233", 
          "https://doi.org/10.1186/s13613-016-0179-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc12792", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006946867", 
          "https://doi.org/10.1186/cc12792"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2022-04-11", 
    "datePublishedReg": "2022-04-11", 
    "description": "BackgroundWhether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time course of septic and non-septic mechanically ventilated patients.MethodsSecondary analysis of two prospective observational studies of mechanically ventilated patients in whom diaphragm function was assessed twice: within the 24\u00a0h after intubation and when patients were switched to pressure support mode, by measuring the endotracheal pressure in response to bilateral anterior magnetic phrenic nerve stimulation (Ptr,stim). Change in diaphragm function was expressed as the difference between Ptr,stim measured under pressure support mode and Ptr,stim measured within the 24\u00a0h after intubation. Sepsis was defined according to the Sepsis-3 international guidelines upon inclusion. In a sub-group of patients, the right hemidiaphragm thickness was measured by ultrasound.ResultsNinety-two patients were enrolled in the study. Sepsis upon intubation was present in 51 (55%) patients. In septic patients, primary reason for ventilation was acute respiratory failure related to pneumonia (37/51; 73%). In non-septic patients, main reasons for ventilation were acute respiratory failure not related to pneumonia (16/41; 39%), coma (13/41; 32%) and cardiac arrest (6/41; 15%). Ptr,stim within 24\u00a0h after intubation was lower in septic patients as compared to non-septic patients: 6.3 (4.9\u20138.7) cmH2O vs. 9.8 (7.0\u201314.2) cmH2O (p\u2009=\u20090.004), respectively. The median (interquartile) duration of mechanical ventilation between first and second diaphragm evaluation was 4 (2\u20136) days in septic patients and 3 (2\u20134) days in non-septic patients (p\u2009=\u20090.073). Between first and second measurements, the change in Ptr,stim was\u2009+\u200919% (\u2212\u200913\u201361) in septic patients and \u2212\u20097% (\u2212\u200940\u201312) in non-septic patients (p\u2009=\u20090.005). In the sub-group of patients with ultrasound measurements, end-expiratory diaphragm thickness decreased in both, septic and non-septic patients. The 28-day mortality was higher in patients with decrease or no change in diaphragm function.ConclusionSeptic patients were associated with a more severe but reversible impaired\u00a0diaphragm function as compared to non-septic patients. Increase in diaphragm function was associated with a better survival.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s13613-022-01005-9", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045300", 
        "issn": [
          "2110-5820"
        ], 
        "name": "Annals of Intensive Care", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "keywords": [
      "non-septic patients", 
      "acute respiratory failure", 
      "diaphragm function", 
      "septic patients", 
      "respiratory failure", 
      "mechanical ventilation", 
      "bilateral anterior magnetic phrenic nerve stimulation", 
      "magnetic phrenic nerve stimulation", 
      "ResultsNinety-two patients", 
      "impaired diaphragm function", 
      "prospective observational study", 
      "phrenic nerve stimulation", 
      "pressure support mode", 
      "support mode", 
      "median duration", 
      "diaphragm dysfunction", 
      "ill patients", 
      "nerve stimulation", 
      "cardiac arrest", 
      "endotracheal pressure", 
      "MethodsSecondary analysis", 
      "observational study", 
      "better survival", 
      "patients", 
      "intubation", 
      "international guidelines", 
      "septic", 
      "ultrasound measurements", 
      "ventilation", 
      "sepsis", 
      "pneumonia", 
      "time course", 
      "second measurement", 
      "diaphragm thickness", 
      "days", 
      "STIM", 
      "failure", 
      "dysfunction", 
      "mortality", 
      "primary reason", 
      "study", 
      "stimulation", 
      "survival", 
      "ultrasound", 
      "coma", 
      "arrest", 
      "exposure", 
      "duration", 
      "changes", 
      "function", 
      "guidelines", 
      "PTR", 
      "course", 
      "main reason", 
      "response", 
      "differences", 
      "decrease", 
      "evaluation", 
      "reasons", 
      "pressure", 
      "inclusion", 
      "analysis", 
      "measurements", 
      "thickness", 
      "mode"
    ], 
    "name": "Severe but reversible impaired diaphragm function in septic mechanically ventilated patients", 
    "pagination": "34", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1146979467"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13613-022-01005-9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "35403916"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13613-022-01005-9", 
      "https://app.dimensions.ai/details/publication/pub.1146979467"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:07", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_926.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s13613-022-01005-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-022-01005-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-022-01005-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-022-01005-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-022-01005-9'


 

This table displays all metadata directly associated to this object as RDF triples.

229 TRIPLES      21 PREDICATES      101 URIs      82 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13613-022-01005-9 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 anzsrc-for:1116
4 schema:author N9b27c3b2e26e4cdcb0a477434cb23103
5 schema:citation sg:pub.10.1007/s00134-017-4928-4
6 sg:pub.10.1007/s00134-019-05892-8
7 sg:pub.10.1007/s10741-010-9176-4
8 sg:pub.10.1186/cc10023
9 sg:pub.10.1186/cc12792
10 sg:pub.10.1186/cc12864
11 sg:pub.10.1186/cc9094
12 sg:pub.10.1186/s13054-018-1992-2
13 sg:pub.10.1186/s13054-020-03338-y
14 sg:pub.10.1186/s13613-016-0179-8
15 schema:datePublished 2022-04-11
16 schema:datePublishedReg 2022-04-11
17 schema:description BackgroundWhether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time course of septic and non-septic mechanically ventilated patients.MethodsSecondary analysis of two prospective observational studies of mechanically ventilated patients in whom diaphragm function was assessed twice: within the 24 h after intubation and when patients were switched to pressure support mode, by measuring the endotracheal pressure in response to bilateral anterior magnetic phrenic nerve stimulation (Ptr,stim). Change in diaphragm function was expressed as the difference between Ptr,stim measured under pressure support mode and Ptr,stim measured within the 24 h after intubation. Sepsis was defined according to the Sepsis-3 international guidelines upon inclusion. In a sub-group of patients, the right hemidiaphragm thickness was measured by ultrasound.ResultsNinety-two patients were enrolled in the study. Sepsis upon intubation was present in 51 (55%) patients. In septic patients, primary reason for ventilation was acute respiratory failure related to pneumonia (37/51; 73%). In non-septic patients, main reasons for ventilation were acute respiratory failure not related to pneumonia (16/41; 39%), coma (13/41; 32%) and cardiac arrest (6/41; 15%). Ptr,stim within 24 h after intubation was lower in septic patients as compared to non-septic patients: 6.3 (4.9–8.7) cmH2O vs. 9.8 (7.0–14.2) cmH2O (p = 0.004), respectively. The median (interquartile) duration of mechanical ventilation between first and second diaphragm evaluation was 4 (2–6) days in septic patients and 3 (2–4) days in non-septic patients (p = 0.073). Between first and second measurements, the change in Ptr,stim was + 19% (− 13–61) in septic patients and − 7% (− 40–12) in non-septic patients (p = 0.005). In the sub-group of patients with ultrasound measurements, end-expiratory diaphragm thickness decreased in both, septic and non-septic patients. The 28-day mortality was higher in patients with decrease or no change in diaphragm function.ConclusionSeptic patients were associated with a more severe but reversible impaired diaphragm function as compared to non-septic patients. Increase in diaphragm function was associated with a better survival.
18 schema:genre article
19 schema:isAccessibleForFree true
20 schema:isPartOf N0baf5da4551643658ccf4d1385c038ac
21 N0e633a46297d4f00bd982df9d2725cd4
22 sg:journal.1045300
23 schema:keywords MethodsSecondary analysis
24 PTR
25 ResultsNinety-two patients
26 STIM
27 acute respiratory failure
28 analysis
29 arrest
30 better survival
31 bilateral anterior magnetic phrenic nerve stimulation
32 cardiac arrest
33 changes
34 coma
35 course
36 days
37 decrease
38 diaphragm dysfunction
39 diaphragm function
40 diaphragm thickness
41 differences
42 duration
43 dysfunction
44 endotracheal pressure
45 evaluation
46 exposure
47 failure
48 function
49 guidelines
50 ill patients
51 impaired diaphragm function
52 inclusion
53 international guidelines
54 intubation
55 magnetic phrenic nerve stimulation
56 main reason
57 measurements
58 mechanical ventilation
59 median duration
60 mode
61 mortality
62 nerve stimulation
63 non-septic patients
64 observational study
65 patients
66 phrenic nerve stimulation
67 pneumonia
68 pressure
69 pressure support mode
70 primary reason
71 prospective observational study
72 reasons
73 respiratory failure
74 response
75 second measurement
76 sepsis
77 septic
78 septic patients
79 stimulation
80 study
81 support mode
82 survival
83 thickness
84 time course
85 ultrasound
86 ultrasound measurements
87 ventilation
88 schema:name Severe but reversible impaired diaphragm function in septic mechanically ventilated patients
89 schema:pagination 34
90 schema:productId N2cb7a7fa0dde4a2baf91d043bac83ec6
91 N555fcd7beedd411798d90d4acf14953d
92 N587e39cd852642d0bfb1dddd962693f0
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1146979467
94 https://doi.org/10.1186/s13613-022-01005-9
95 schema:sdDatePublished 2022-09-02T16:07
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher N11791ac161a748149e725d53780b2591
98 schema:url https://doi.org/10.1186/s13613-022-01005-9
99 sgo:license sg:explorer/license/
100 sgo:sdDataset articles
101 rdf:type schema:ScholarlyArticle
102 N0baf5da4551643658ccf4d1385c038ac schema:issueNumber 1
103 rdf:type schema:PublicationIssue
104 N0e633a46297d4f00bd982df9d2725cd4 schema:volumeNumber 12
105 rdf:type schema:PublicationVolume
106 N11791ac161a748149e725d53780b2591 schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N2cb7a7fa0dde4a2baf91d043bac83ec6 schema:name dimensions_id
109 schema:value pub.1146979467
110 rdf:type schema:PropertyValue
111 N36d1934e37a24c348b0dada6a55dbe08 rdf:first sg:person.01113242353.35
112 rdf:rest Ne4202457efaf4351afc1570b163d77af
113 N3a6e14e834924c17999185f05059885a rdf:first sg:person.012402413440.08
114 rdf:rest Nee0171de66c44700af78f363a77edb92
115 N5119b8d25452469c9a93f47681375b21 rdf:first sg:person.01120203457.34
116 rdf:rest rdf:nil
117 N555fcd7beedd411798d90d4acf14953d schema:name pubmed_id
118 schema:value 35403916
119 rdf:type schema:PropertyValue
120 N587e39cd852642d0bfb1dddd962693f0 schema:name doi
121 schema:value 10.1186/s13613-022-01005-9
122 rdf:type schema:PropertyValue
123 N9b27c3b2e26e4cdcb0a477434cb23103 rdf:first sg:person.01362670477.14
124 rdf:rest Naf44c5a43fe24c1592cca15dcb3b8172
125 Nae536424df88460597c652a59e18f0a8 rdf:first sg:person.01266343767.08
126 rdf:rest N3a6e14e834924c17999185f05059885a
127 Naf44c5a43fe24c1592cca15dcb3b8172 rdf:first sg:person.01230435413.18
128 rdf:rest Nae536424df88460597c652a59e18f0a8
129 Ne4202457efaf4351afc1570b163d77af rdf:first sg:person.0673253666.83
130 rdf:rest N5119b8d25452469c9a93f47681375b21
131 Nee0171de66c44700af78f363a77edb92 rdf:first sg:person.01235111105.45
132 rdf:rest N36d1934e37a24c348b0dada6a55dbe08
133 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
134 schema:name Medical and Health Sciences
135 rdf:type schema:DefinedTerm
136 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
137 schema:name Clinical Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1116 schema:inDefinedTermSet anzsrc-for:
140 schema:name Medical Physiology
141 rdf:type schema:DefinedTerm
142 sg:journal.1045300 schema:issn 2110-5820
143 schema:name Annals of Intensive Care
144 schema:publisher Springer Nature
145 rdf:type schema:Periodical
146 sg:person.01113242353.35 schema:affiliation grid-institutes:grid.121334.6
147 schema:familyName Jaber
148 schema:givenName Samir
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113242353.35
150 rdf:type schema:Person
151 sg:person.01120203457.34 schema:affiliation grid-institutes:grid.462844.8
152 schema:familyName Dres
153 schema:givenName Martin
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120203457.34
155 rdf:type schema:Person
156 sg:person.01230435413.18 schema:affiliation grid-institutes:grid.121334.6
157 schema:familyName Jung
158 schema:givenName Boris
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230435413.18
160 rdf:type schema:Person
161 sg:person.01235111105.45 schema:affiliation grid-institutes:grid.462844.8
162 schema:familyName Similowski
163 schema:givenName Thomas
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235111105.45
165 rdf:type schema:Person
166 sg:person.012402413440.08 schema:affiliation grid-institutes:grid.411439.a
167 schema:familyName Pinot
168 schema:givenName Jérôme
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012402413440.08
170 rdf:type schema:Person
171 sg:person.01266343767.08 schema:affiliation grid-institutes:grid.413745.0
172 schema:familyName Molinari
173 schema:givenName Nicolas
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266343767.08
175 rdf:type schema:Person
176 sg:person.01362670477.14 schema:affiliation grid-institutes:grid.462844.8
177 schema:familyName Lecronier
178 schema:givenName Marie
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362670477.14
180 rdf:type schema:Person
181 sg:person.0673253666.83 schema:affiliation grid-institutes:grid.462844.8
182 schema:familyName Demoule
183 schema:givenName Alexandre
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673253666.83
185 rdf:type schema:Person
186 sg:pub.10.1007/s00134-017-4928-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091765651
187 https://doi.org/10.1007/s00134-017-4928-4
188 rdf:type schema:CreativeWork
189 sg:pub.10.1007/s00134-019-05892-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1124076869
190 https://doi.org/10.1007/s00134-019-05892-8
191 rdf:type schema:CreativeWork
192 sg:pub.10.1007/s10741-010-9176-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028599545
193 https://doi.org/10.1007/s10741-010-9176-4
194 rdf:type schema:CreativeWork
195 sg:pub.10.1186/cc10023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037336704
196 https://doi.org/10.1186/cc10023
197 rdf:type schema:CreativeWork
198 sg:pub.10.1186/cc12792 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006946867
199 https://doi.org/10.1186/cc12792
200 rdf:type schema:CreativeWork
201 sg:pub.10.1186/cc12864 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037241624
202 https://doi.org/10.1186/cc12864
203 rdf:type schema:CreativeWork
204 sg:pub.10.1186/cc9094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024386586
205 https://doi.org/10.1186/cc9094
206 rdf:type schema:CreativeWork
207 sg:pub.10.1186/s13054-018-1992-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101629732
208 https://doi.org/10.1186/s13054-018-1992-2
209 rdf:type schema:CreativeWork
210 sg:pub.10.1186/s13054-020-03338-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1132948548
211 https://doi.org/10.1186/s13054-020-03338-y
212 rdf:type schema:CreativeWork
213 sg:pub.10.1186/s13613-016-0179-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026819233
214 https://doi.org/10.1186/s13613-016-0179-8
215 rdf:type schema:CreativeWork
216 grid-institutes:grid.121334.6 schema:alternateName Laboratoire de Physiologie et Médecine Expérimentale du cœur et des Muscles, INSERM U1046-CNRS UMR 9214, Université de Montpellier, Montpellier, France
217 schema:name Département de Médecine Intensive - Réanimation, CHU Montpellier, Montpellier, France
218 Laboratoire de Physiologie et Médecine Expérimentale du cœur et des Muscles, INSERM U1046-CNRS UMR 9214, Université de Montpellier, Montpellier, France
219 rdf:type schema:Organization
220 grid-institutes:grid.411439.a schema:alternateName Médecine Intensive - Réanimation (Département “R3S”), APHP. Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France
221 schema:name Médecine Intensive - Réanimation (Département “R3S”), APHP. Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France
222 rdf:type schema:Organization
223 grid-institutes:grid.413745.0 schema:alternateName Department of Medical Information, Hôpital Arnaud de Villeneuve, IMAG U5149, Université de Montpellier, Montpellier, France
224 schema:name Department of Medical Information, Hôpital Arnaud de Villeneuve, IMAG U5149, Université de Montpellier, Montpellier, France
225 rdf:type schema:Organization
226 grid-institutes:grid.462844.8 schema:alternateName Neurophysiologie Respiratoire Expérimentale et Clinique, INSERM-UMR S 1158, Sorbonne Université, Paris, France
227 schema:name Médecine Intensive - Réanimation (Département “R3S”), APHP. Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France
228 Neurophysiologie Respiratoire Expérimentale et Clinique, INSERM-UMR S 1158, Sorbonne Université, Paris, France
229 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...