Ontology type: schema:ScholarlyArticle Open Access: True
2020-05-07
AUTHORSEtienne de Montmollin, Nicolas Terzi, Claire Dupuis, Maité Garrouste-Orgeas, Daniel da Silva, Michaël Darmon, Virginie Laurent, Guillaume Thiéry, Johana Oziel, Guillaume Marcotte, Marc Gainnier, Shidasp Siami, Benjamin Sztrymf, Christophe Adrie, Jean Reignier, Stephane Ruckly, Romain Sonneville, Jean-François Timsit
ABSTRACTBackgroundMost prognostic studies in acute stroke patients requiring invasive mechanical ventilation are outdated and have limitations such as single-center retrospective designs. We aimed to study the association of ICU admission factors, including the reason for intubation, with 1-year survival of acute stroke patients requiring mechanical ventilation.MethodsWe conducted a secondary data use analysis of a prospective multicenter database (14 ICUs) between 1997 and 2016 on consecutive ICU stroke patients requiring mechanical ventilation at admission. We excluded patients with stroke of traumatic origin, subdural hematoma or cerebral venous thrombosis. The primary outcome was survival 1 year after ICU admission. Factors associated with the primary outcome were identified using a multivariable Cox model stratified on inclusion center.ResultsWe identified 419 patients (age 68 [58–76] years, males 60%) with a Glasgow coma score (GCS) of 4 [3–8] at admission. Stroke subtypes were acute ischemic stroke (AIS, 46%), intracranial hemorrhage (ICH, 42%) and subarachnoid hemorrhage (SAH, 12%). At 1 year, 96 (23%) patients were alive. Factors independently associated with decreased 1-year survival were ICH and SAH stroke subtypes, a lower GCS score at admission, a higher non-neurological SOFA score. Conversely, patients receiving acute-phase therapy had improved 1-year survival. Intubation for acute respiratory failure or coma was associated with comparable survival hazard ratios, whereas intubation for seizure was not associated with a worse prognosis than for elective procedure. Survival did not improve over the study period, but patients included in the most recent period had more comorbidities and presented higher severity scores at admission.ConclusionsIn acute stroke patients requiring mechanical ventilation, the reason for intubation and the opportunity to receive acute-phase stroke therapy were independently associated with 1-year survival. These variables could assist in the decision process regarding the initiation of mechanical ventilation in acute stroke patients. More... »
PAGES53
http://scigraph.springernature.com/pub.10.1186/s13613-020-00669-5
DOIhttp://dx.doi.org/10.1186/s13613-020-00669-5
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1127449968
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/32383104
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "APHP, Medical and Infectious Diseases Intensive Care Unit, Bichat-Claude Bernard Hospital, 46 Rue Henri Huchard, 75018, Paris, France",
"id": "http://www.grid.ac/institutes/grid.411119.d",
"name": [
"Universit\u00e9 de Paris, UMR 1137, IAME, Paris, France",
"APHP, Medical and Infectious Diseases Intensive Care Unit, Bichat-Claude Bernard Hospital, 46 Rue Henri Huchard, 75018, Paris, France"
],
"type": "Organization"
},
"familyName": "de Montmollin",
"givenName": "Etienne",
"id": "sg:person.0615463126.53",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615463126.53"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Intensive Care Unit, Grenoble University Hospital, La Tronche, France",
"id": "http://www.grid.ac/institutes/grid.410529.b",
"name": [
"Medical Intensive Care Unit, Grenoble University Hospital, La Tronche, France"
],
"type": "Organization"
},
"familyName": "Terzi",
"givenName": "Nicolas",
"id": "sg:person.0674721071.11",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674721071.11"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France",
"id": "http://www.grid.ac/institutes/grid.411163.0",
"name": [
"Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France"
],
"type": "Organization"
},
"familyName": "Dupuis",
"givenName": "Claire",
"id": "sg:person.012767575165.82",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012767575165.82"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Unit, French British Hospital, Levallois-Perret, France",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Medical Unit, French British Hospital, Levallois-Perret, France"
],
"type": "Organization"
},
"familyName": "Garrouste-Orgeas",
"givenName": "Mait\u00e9",
"id": "sg:person.01255251103.71",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255251103.71"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Intensive Care Unit, Delafontaine Hospital, Saint-Denis, France",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Intensive Care Unit, Delafontaine Hospital, Saint-Denis, France"
],
"type": "Organization"
},
"familyName": "da Silva",
"givenName": "Daniel",
"id": "sg:person.0705142745.67",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705142745.67"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Intensive Care Unit, Saint-Louis Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413328.f",
"name": [
"Medical Intensive Care Unit, Saint-Louis Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Darmon",
"givenName": "Micha\u00ebl",
"id": "sg:person.01027641050.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027641050.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Intensive Care Unit, Andr\u00e9 Mignot Hospital, Le Chesnay, France",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Intensive Care Unit, Andr\u00e9 Mignot Hospital, Le Chesnay, France"
],
"type": "Organization"
},
"familyName": "Laurent",
"givenName": "Virginie",
"id": "sg:person.01023652002.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023652002.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Intensive Care Unit, H\u00f4pital Nord, Saint-Etienne, France",
"id": "http://www.grid.ac/institutes/grid.414244.3",
"name": [
"Intensive Care Unit, H\u00f4pital Nord, Saint-Etienne, France"
],
"type": "Organization"
},
"familyName": "Thi\u00e9ry",
"givenName": "Guillaume",
"id": "sg:person.01030405024.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030405024.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "APHP, Intensive Care Unit, Avicenne Hospital, Bobigny, France",
"id": "http://www.grid.ac/institutes/grid.413780.9",
"name": [
"APHP, Intensive Care Unit, Avicenne Hospital, Bobigny, France"
],
"type": "Organization"
},
"familyName": "Oziel",
"givenName": "Johana",
"id": "sg:person.012712273413.45",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012712273413.45"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Surgical Intensive Care Unit, Lyon, France",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Surgical Intensive Care Unit, Lyon, France"
],
"type": "Organization"
},
"familyName": "Marcotte",
"givenName": "Guillaume",
"id": "sg:person.0700066673.74",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700066673.74"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Intensive Care Unit, La Timone Hospital, Marseille, France",
"id": "http://www.grid.ac/institutes/grid.411266.6",
"name": [
"Intensive Care Unit, La Timone Hospital, Marseille, France"
],
"type": "Organization"
},
"familyName": "Gainnier",
"givenName": "Marc",
"id": "sg:person.01213542764.59",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213542764.59"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Intensive Care Unit, Sud-Essonne Hospital, Etampes, France",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Intensive Care Unit, Sud-Essonne Hospital, Etampes, France"
],
"type": "Organization"
},
"familyName": "Siami",
"givenName": "Shidasp",
"id": "sg:person.0771074230.67",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771074230.67"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "APHP, Intensive Care Unit, Antoine B\u00e9cl\u00e8re Hospital, Clamart, France",
"id": "http://www.grid.ac/institutes/grid.413738.a",
"name": [
"APHP, Intensive Care Unit, Antoine B\u00e9cl\u00e8re Hospital, Clamart, France"
],
"type": "Organization"
},
"familyName": "Sztrymf",
"givenName": "Benjamin",
"id": "sg:person.0731336057.13",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731336057.13"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "APHP, Physiology Department, Cochin Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.411784.f",
"name": [
"APHP, Physiology Department, Cochin Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Adrie",
"givenName": "Christophe",
"id": "sg:person.01172527264.26",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172527264.26"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Intensive Care Unit, Nantes University Hospital, Nantes, France",
"id": "http://www.grid.ac/institutes/grid.277151.7",
"name": [
"Medical Intensive Care Unit, Nantes University Hospital, Nantes, France"
],
"type": "Organization"
},
"familyName": "Reignier",
"givenName": "Jean",
"id": "sg:person.01342156037.26",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342156037.26"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e9 de Paris, UMR 1137, IAME, Paris, France",
"id": "http://www.grid.ac/institutes/grid.508487.6",
"name": [
"Universit\u00e9 de Paris, UMR 1137, IAME, Paris, France"
],
"type": "Organization"
},
"familyName": "Ruckly",
"givenName": "Stephane",
"id": "sg:person.01013767315.45",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013767315.45"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e9 de Paris, UMR 1148, LVTS, Paris, France",
"id": "http://www.grid.ac/institutes/grid.508487.6",
"name": [
"APHP, Medical and Infectious Diseases Intensive Care Unit, Bichat-Claude Bernard Hospital, 46 Rue Henri Huchard, 75018, Paris, France",
"Universit\u00e9 de Paris, UMR 1148, LVTS, Paris, France"
],
"type": "Organization"
},
"familyName": "Sonneville",
"givenName": "Romain",
"id": "sg:person.01342423100.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342423100.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "APHP, Medical and Infectious Diseases Intensive Care Unit, Bichat-Claude Bernard Hospital, 46 Rue Henri Huchard, 75018, Paris, France",
"id": "http://www.grid.ac/institutes/grid.411119.d",
"name": [
"Universit\u00e9 de Paris, UMR 1137, IAME, Paris, France",
"APHP, Medical and Infectious Diseases Intensive Care Unit, Bichat-Claude Bernard Hospital, 46 Rue Henri Huchard, 75018, Paris, France"
],
"type": "Organization"
},
"familyName": "Timsit",
"givenName": "Jean-Fran\u00e7ois",
"id": "sg:person.01215000253.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215000253.20"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/bf02425052",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053030133",
"https://doi.org/10.1007/bf02425052"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-016-4553-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050044470",
"https://doi.org/10.1007/s00134-016-4553-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00415-005-0711-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038649385",
"https://doi.org/10.1007/s00415-005-0711-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-019-05705-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1119862240",
"https://doi.org/10.1007/s00134-019-05705-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s12028-014-0082-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019872522",
"https://doi.org/10.1007/s12028-014-0082-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-015-3944-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009808266",
"https://doi.org/10.1007/s00134-015-3944-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s001340100998",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041461115",
"https://doi.org/10.1007/s001340100998"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01709751",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052044737",
"https://doi.org/10.1007/bf01709751"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-013-2949-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007353747",
"https://doi.org/10.1007/s00134-013-2949-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-016-4404-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001895976",
"https://doi.org/10.1007/s00134-016-4404-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-014-3289-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018034369",
"https://doi.org/10.1007/s00134-014-3289-5"
],
"type": "CreativeWork"
}
],
"datePublished": "2020-05-07",
"datePublishedReg": "2020-05-07",
"description": "BackgroundMost prognostic studies in acute stroke patients requiring invasive mechanical ventilation are outdated and have limitations such as single-center retrospective designs. We aimed to study the association of ICU admission factors, including the reason for intubation, with 1-year survival of acute stroke patients requiring mechanical ventilation.MethodsWe conducted a secondary data use analysis of a prospective multicenter database (14 ICUs) between 1997 and 2016 on consecutive ICU stroke patients requiring mechanical ventilation at admission. We excluded patients with stroke of traumatic origin, subdural hematoma or cerebral venous thrombosis. The primary outcome was survival 1\u00a0year after ICU admission. Factors associated with the primary outcome were identified using a multivariable Cox model stratified on inclusion center.ResultsWe identified 419 patients (age 68 [58\u201376] years, males 60%) with a Glasgow coma score (GCS) of 4 [3\u20138] at admission. Stroke subtypes were acute ischemic stroke (AIS, 46%), intracranial hemorrhage (ICH, 42%) and subarachnoid hemorrhage (SAH, 12%). At 1\u00a0year, 96 (23%) patients were alive. Factors independently associated with decreased 1-year survival were ICH and SAH stroke subtypes, a lower GCS score at admission, a higher non-neurological SOFA score. Conversely, patients receiving acute-phase therapy had improved 1-year survival. Intubation for acute respiratory failure or coma was associated with comparable survival hazard ratios, whereas intubation for seizure was not associated with a worse prognosis than for elective procedure. Survival did not improve over the study period, but patients included in the most recent period had more comorbidities and presented higher severity scores at admission.ConclusionsIn acute stroke patients requiring mechanical ventilation, the reason for intubation and the opportunity to receive acute-phase stroke therapy were independently associated with 1-year survival. These variables could assist in the decision process regarding the initiation of mechanical ventilation in acute stroke patients.",
"genre": "article",
"id": "sg:pub.10.1186/s13613-020-00669-5",
"inLanguage": "en",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1045300",
"issn": [
"2110-5820"
],
"name": "Annals of Intensive Care",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "10"
}
],
"keywords": [
"acute stroke patients",
"Glasgow Coma Score",
"stroke patients",
"mechanical ventilation",
"primary outcome",
"stroke subtypes",
"single-center retrospective design",
"prospective multicenter database",
"acute phase therapy",
"invasive mechanical ventilation",
"cerebral venous thrombosis",
"multivariable Cox model",
"acute respiratory failure",
"multicenter cohort study",
"acute ischemic stroke",
"survival hazard ratio",
"One-year survival",
"lower GCS score",
"higher severity scores",
"SOFA score",
"more comorbidities",
"ICU admission",
"respiratory failure",
"Coma Score",
"ischemic stroke",
"hazard ratio",
"cohort study",
"venous thrombosis",
"GCS score",
"multicenter database",
"worse prognosis",
"stroke therapy",
"subdural hematoma",
"intracranial hemorrhage",
"elective procedures",
"severity score",
"survival 1",
"retrospective design",
"prognostic studies",
"Cox model",
"patients",
"intubation",
"admission",
"traumatic origin",
"study period",
"ventilation",
"admission factors",
"survival",
"hemorrhage",
"scores",
"therapy",
"stroke",
"subtypes",
"outcomes",
"hematoma",
"comorbidities",
"thrombosis",
"prognosis",
"seizures",
"years",
"factors",
"MethodsWe",
"ResultsWe",
"coma",
"period",
"study",
"association",
"ICH",
"failure",
"initiation",
"database",
"center",
"reasons",
"procedure",
"variables",
"inclusion center",
"ratio",
"recent period",
"analysis",
"origin",
"limitations",
"opportunities",
"model",
"design",
"process",
"decision process",
"use analysis"
],
"name": "One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study",
"pagination": "53",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1127449968"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13613-020-00669-5"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"32383104"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13613-020-00669-5",
"https://app.dimensions.ai/details/publication/pub.1127449968"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:36",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_834.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1186/s13613-020-00669-5"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-020-00669-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-020-00669-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-020-00669-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-020-00669-5'
This table displays all metadata directly associated to this object as RDF triples.
356 TRIPLES
22 PREDICATES
124 URIs
105 LITERALS
7 BLANK NODES