Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSFranck Ehooman, Lucie Biard, Virginie Lemiale, Damien Contou, Nicolas de Prost, Djamel Mokart, Frédéric Pène, Achille Kouatchet, Julien Mayaux, Alexandre Demoule, François Vincent, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Christine Lebert, Pierre Perez, Anne-Pascale Meert, Dominique Benoit, Rebecca Hamidfar, Michael Darmon, Elie Azoulay, Lara Zafrani
ABSTRACTBACKGROUND: Although outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQOL) in this population. We aim to assess post-intensive care unit (ICU) burden and HRQOL of critically ill patients with HMs and to identify risk factors for quality-of-life (QOL) impairment. RESULTS: In total, 1011 patients with HMs who required ICU admission in 17 ICUs in France and Belgium were included in the study; 278 and 117 patients were evaluated for QOL at 3 months and 1 year, respectively, after ICU discharge. HRQOL was determined by applying the interview form of the Short Form 36 (SF-36) questionnaire. Psychological distress symptoms were evaluated using the Hospital Anxiety Depression Score (HADS) and the Impact of Event Scale (IES). In-hospital mortality rates at 3 months and 1 year were, respectively, 39.1, 50.7 and 57.2%, respectively. At 3 months, median [IQR] physical and mental component summary scores (PCS and MCS) (SF-36) were 37 [28-46] and 51 [45-58], respectively. PCS was lower in ICU patients with HMs when compared to general ICU septic patients (52 [5-13], p = 0.00001). The median combined HAD score was 8 [5-13], and the median IES score was 8 [3-16]. However, recovery during the first year after ICU discharge was not consistent in all dimensions of HRQOL. Three months after ICU discharge, the maximum daily Sequential Organ Failure Assessment score and status of the underlying malignancy at ICU admission were significantly associated with MCS impairment (- 0.54 points [95% CI - 0.99; - 0.1], p = 0.018 and - 4.83 points [95% CI - 8.44; - 1.22], p = 0.009, respectively). CONCLUSION: HRQOL is strongly impaired in critically ill patients with HMs at 3 months and 1 year after ICU discharge. Organ failure and disease status are strongly associated with QOL. The kinetic evaluation of QOL at 3 months and 1 year offers the opportunity to focus on QOL aspects that may be improved by therapeutic interventions during the first year after ICU discharge. More... »
PAGES2
http://scigraph.springernature.com/pub.10.1186/s13613-018-0478-3
DOIhttp://dx.doi.org/10.1186/s13613-018-0478-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1111158116
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30612249
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Medical ICU, Saint-Louis Teaching Hospital, 1 Avenue Claude Vellefaux, 75010, Paris, France"
],
"type": "Organization"
},
"familyName": "Ehooman",
"givenName": "Franck",
"id": "sg:person.012724772413.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012724772413.99"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Biostatistics Department, Saint-Louis Teaching Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Biard",
"givenName": "Lucie",
"id": "sg:person.01365034601.15",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365034601.15"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Saint-Louis Teaching Hospital, 1 Avenue Claude Vellefaux, 75010, Paris, France"
],
"type": "Organization"
},
"familyName": "Lemiale",
"givenName": "Virginie",
"id": "sg:person.01027707313.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027707313.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Grenoble",
"id": "https://www.grid.ac/institutes/grid.410529.b",
"name": [
"Medical ICU, Henri Mondor Teaching Hospital, Paris, France",
"ICU, Albert Michallon University Hospital, Grenoble, France",
"ICU, Saint-Etienne University Hospital, Saint-Etienne, France"
],
"type": "Organization"
},
"familyName": "Contou",
"givenName": "Damien",
"id": "sg:person.01020102105.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020102105.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Grenoble",
"id": "https://www.grid.ac/institutes/grid.410529.b",
"name": [
"Medical ICU, Henri Mondor Teaching Hospital, Paris, France",
"ICU, Albert Michallon University Hospital, Grenoble, France",
"ICU, Saint-Etienne University Hospital, Saint-Etienne, France"
],
"type": "Organization"
},
"familyName": "de Prost",
"givenName": "Nicolas",
"type": "Person"
},
{
"affiliation": {
"alternateName": "H\u00f4pitaux Universitaires Henri Mondor",
"id": "https://www.grid.ac/institutes/grid.412116.1",
"name": [
"Medical ICU, Henri Mondor Teaching Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Mokart",
"givenName": "Djamel",
"id": "sg:person.0712223761.03",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712223761.03"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Paoli Calmette Institute, Marseille, France"
],
"type": "Organization"
},
"familyName": "P\u00e8ne",
"givenName": "Fr\u00e9d\u00e9ric",
"id": "sg:person.01131725526.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131725526.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "H\u00f4pital Cochin",
"id": "https://www.grid.ac/institutes/grid.411784.f",
"name": [
"Medical ICU, Cochin Teaching Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Kouatchet",
"givenName": "Achille",
"id": "sg:person.01172201120.81",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172201120.81"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Angers Teaching Hospital, Angers, France"
],
"type": "Organization"
},
"familyName": "Mayaux",
"givenName": "Julien",
"id": "sg:person.01256512217.24",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256512217.24"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Angers Teaching Hospital, Angers, France"
],
"type": "Organization"
},
"familyName": "Demoule",
"givenName": "Alexandre",
"id": "sg:person.0673253666.83",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673253666.83"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Piti\u00e9-Salp\u00e9tri\u00e8re Teaching Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Vincent",
"givenName": "Fran\u00e7ois",
"id": "sg:person.01106433227.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106433227.02"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Avicenne Teaching Hospital, Bobigny, France"
],
"type": "Organization"
},
"familyName": "Nyunga",
"givenName": "Martine",
"id": "sg:person.01056664465.45",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056664465.45"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Roubaix Hospital, Roubaix, France"
],
"type": "Organization"
},
"familyName": "Bruneel",
"givenName": "Fabrice",
"id": "sg:person.01210722404.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210722404.05"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Mignot Hospital, Versailles, France"
],
"type": "Organization"
},
"familyName": "Rabbat",
"givenName": "Antoine",
"id": "sg:person.01267736170.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267736170.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "H\u00f4pital Cochin",
"id": "https://www.grid.ac/institutes/grid.411784.f",
"name": [
"Respiratory Unit, Cochin Teaching Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Lebert",
"givenName": "Christine",
"id": "sg:person.01106025543.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106025543.01"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Vend\u00e9e hospital, La Roche sur Yon, France"
],
"type": "Organization"
},
"familyName": "Perez",
"givenName": "Pierre",
"id": "sg:person.01110107664.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110107664.20"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Brabois Teaching Hospital, Nancy, France"
],
"type": "Organization"
},
"familyName": "Meert",
"givenName": "Anne-Pascale",
"id": "sg:person.0760414175.48",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760414175.48"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Institut Jules Bordet",
"id": "https://www.grid.ac/institutes/grid.418119.4",
"name": [
"Service soins intensifs et urgences oncologiques, Institut Jules Bordet, Brussels, Belgium"
],
"type": "Organization"
},
"familyName": "Benoit",
"givenName": "Dominique",
"id": "sg:person.01225564344.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225564344.52"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"ICU, Ghent Teaching Hospital, Ghent, Belgium"
],
"type": "Organization"
},
"familyName": "Hamidfar",
"givenName": "Rebecca",
"id": "sg:person.0637015115.97",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637015115.97"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Centre Hospitalier Universitaire de Grenoble",
"id": "https://www.grid.ac/institutes/grid.410529.b",
"name": [
"ICU, Albert Michallon University Hospital, Grenoble, France"
],
"type": "Organization"
},
"familyName": "Darmon",
"givenName": "Michael",
"id": "sg:person.01027641050.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027641050.35"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Saint-Louis Teaching Hospital, 1 Avenue Claude Vellefaux, 75010, Paris, France"
],
"type": "Organization"
},
"familyName": "Azoulay",
"givenName": "Elie",
"id": "sg:person.01352577613.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352577613.57"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Medical ICU, Saint-Louis Teaching Hospital, 1 Avenue Claude Vellefaux, 75010, Paris, France"
],
"type": "Organization"
},
"familyName": "Zafrani",
"givenName": "Lara",
"id": "sg:person.01042424464.15",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042424464.15"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1097/00005650-199401000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000969773"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005650-199401000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000969773"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e3181cd10c7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005609119"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e3181cd10c7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005609119"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s001340050931",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007286393",
"https://doi.org/10.1007/s001340050931"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0447.1983.tb09716.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011377221"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0021-9681(87)90171-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020988115"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1586/14737167.4.2.159",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021690188"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/pon.3026",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021889038"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00520-015-2923-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022627587",
"https://doi.org/10.1007/s00520-015-2923-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-002-1624-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023523838",
"https://doi.org/10.1007/s00134-002-1624-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2012.47.2365",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024078071"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00003246-200007000-00018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027462369"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00003246-200007000-00018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027462369"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000065188.87029.c3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027502488"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.ccm.0000065188.87029.c3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027502488"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/cc5970",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029876732",
"https://doi.org/10.1186/cc5970"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00006842-197905000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029900423"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00006842-197905000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029900423"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3324/haematol.2010.031583",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030263154"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005650-199206000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030545431"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005650-199206000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030545431"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1164/rccm.201001-0018oc",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033584662"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.286.14.1754",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033991989"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa1503326",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035211734"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-016-4530-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036121822",
"https://doi.org/10.1007/s00134-016-4530-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-016-4530-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036121822",
"https://doi.org/10.1007/s00134-016-4530-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13054-016-1537-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036790767",
"https://doi.org/10.1186/s13054-016-1537-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13054-016-1537-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036790767",
"https://doi.org/10.1186/s13054-016-1537-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e3181e2c8b1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039286049"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e3181e2c8b1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039286049"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1378/chest.07-1217",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040751546"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0895-4356(98)00093-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041936664"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11136-010-9740-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043240574",
"https://doi.org/10.1007/s11136-010-9740-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e318186a3e7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043261330"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0b013e318186a3e7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043261330"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2044.2001.01714.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044806460"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2006.05.7869",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046680842"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-012-2791-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047128017",
"https://doi.org/10.1007/s00134-012-2791-x"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.brat.2003.07.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048677398"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.brat.2003.07.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048677398"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/pon.3829",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049605615"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0000000000000882",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050216061"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/ccm.0000000000000882",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050216061"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13613-015-0053-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050781117",
"https://doi.org/10.1186/s13613-015-0053-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13613-015-0053-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050781117",
"https://doi.org/10.1186/s13613-015-0053-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01709751",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052044737",
"https://doi.org/10.1007/bf01709751"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01709751",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052044737",
"https://doi.org/10.1007/bf01709751"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076985107",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082480075",
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-017-4698-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083829119",
"https://doi.org/10.1007/s00134-017-4698-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-017-4698-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083829119",
"https://doi.org/10.1007/s00134-017-4698-z"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/epirev/mxx007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083931539"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jcrc.2017.09.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091494460"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1100423702",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/anae.14444",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107428288"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/anae.14444",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107428288"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/anae.14444",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107428288"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-12",
"datePublishedReg": "2019-12-01",
"description": "BACKGROUND: Although outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQOL) in this population. We aim to assess post-intensive care unit (ICU) burden and HRQOL of critically ill patients with HMs and to identify risk factors for quality-of-life (QOL) impairment.\nRESULTS: In total, 1011 patients with HMs who required ICU admission in 17 ICUs in France and Belgium were included in the study; 278 and 117 patients were evaluated for QOL at 3\u00a0months and 1\u00a0year, respectively, after ICU discharge. HRQOL was determined by applying the interview form of the Short Form 36 (SF-36) questionnaire. Psychological distress symptoms were evaluated using the Hospital Anxiety Depression Score (HADS) and the Impact of Event Scale (IES). In-hospital mortality rates at 3\u00a0months and 1\u00a0year were, respectively, 39.1, 50.7 and 57.2%, respectively. At 3\u00a0months, median [IQR] physical and mental component summary scores (PCS and MCS) (SF-36) were 37 [28-46] and 51 [45-58], respectively. PCS was lower in ICU patients with HMs when compared to general ICU septic patients (52 [5-13], p\u2009=\u20090.00001). The median combined HAD score was 8 [5-13], and the median IES score was 8 [3-16]. However, recovery during the first year after ICU discharge was not consistent in all dimensions of HRQOL. Three months after ICU discharge, the maximum daily Sequential Organ Failure Assessment score and status of the underlying malignancy at ICU admission were significantly associated with MCS impairment (-\u20090.54 points [95% CI -\u20090.99; -\u20090.1], p\u2009=\u20090.018 and -\u20094.83 points [95% CI -\u20098.44; -\u20091.22], p\u2009=\u20090.009, respectively).\nCONCLUSION: HRQOL is strongly impaired in critically ill patients with HMs at 3\u00a0months and 1\u00a0year after ICU discharge. Organ failure and disease status are strongly associated with QOL. The kinetic evaluation of QOL at 3\u00a0months and 1\u00a0year offers the opportunity to focus on QOL aspects that may be improved by therapeutic interventions during the first year after ICU discharge.",
"genre": "research_article",
"id": "sg:pub.10.1186/s13613-018-0478-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1045300",
"issn": [
"2110-5820"
],
"name": "Annals of Intensive Care",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "9"
}
],
"name": "Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study",
"pagination": "2",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"310764d64089b4997917c1cfa8538f0119d6e51d6570a3feb9d3b0dc2091bdde"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30612249"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101562873"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13613-018-0478-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1111158116"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13613-018-0478-3",
"https://app.dimensions.ai/details/publication/pub.1111158116"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T08:42",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000322_0000000322/records_64986_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1186%2Fs13613-018-0478-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0478-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0478-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0478-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0478-3'
This table displays all metadata directly associated to this object as RDF triples.
387 TRIPLES
21 PREDICATES
70 URIs
21 LITERALS
9 BLANK NODES