ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12-17

AUTHORS

A. S. Truche, S. Perinel Ragey, B. Souweine, S. Bailly, L. Zafrani, L. Bouadma, C. Clec’h, M. Garrouste-Orgeas, G. Lacave, C. Schwebel, F. Guebre-Egziabher, C. Adrie, A. S. Dumenil, Ph. Zaoui, L. Argaud, S. Jamali, D. Goldran Toledano, G. Marcotte, J. F. Timsit, M. Darmon

ABSTRACT

BackgroundTransient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.DesignRetrospective analysis of a prospective database via cause-specific model, with 28-day ICU mortality as primary end point, considering discharge alive as a competing event and taking into account time-dependent nature of renal recovery. Renal recovery was defined as a decrease of at least one KDIGO class compared to the previous day.Setting23 French ICUs.PatientsPatients of a French multicentric observational cohort were included if they suffered from AKI at ICU admission between 1996 and 2015.InterventionNone.ResultsA total of 5242 patients were included. Initial severity according to KDIGO creatinine definition was AKI stage 1 for 2458 patients (46.89%), AKI stage 2 for 1181 (22.53%) and AKI stage 3 for 1603 (30.58%). Crude 28-day ICU mortality according to AKI severity was 22.74% (n = 559), 27.69% (n = 327) and 26.26% (n = 421), respectively. Renal recovery was experienced by 3085 patients (58.85%), and its rate was significantly different between AKI severity stages (P < 0.01). Twenty-eight-day ICU mortality was independently lower in patients experiencing renal recovery [CSHR 0.54 (95% CI 0.46–0.63), P < 0.01]. Lastly, RRT requirement was strongly associated with persistent AKI whichever threshold was chosen between day 2 and 7 to delineate transient from persistent AKI.ConclusionsShort-term renal recovery, according to several definitions, was independently associated with higher mortality and RRT requirement. Moreover, distinction between transient and persistent AKI is consequently a clinically relevant surrogate outcome variable for diagnostic testing in critically ill patients. More... »

PAGES

127

References to SciGraph publications

  • 2013-06-27. Duration of acute kidney injury and mortality in critically ill patients: a retrospective observational study in BMC NEPHROLOGY
  • 2015-07-11. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study in INTENSIVE CARE MEDICINE
  • 2011-07-27. Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study in CRITICAL CARE
  • 2011-05-17. Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysis in CRITICAL CARE
  • 2013-02-04. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1) in CRITICAL CARE
  • 2012-07-12. One-year mortality among Danish intensive care patients with acute kidney injury: a cohort study in CRITICAL CARE
  • 2008-04-02. Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models in CRITICAL CARE
  • 2007-03-01. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury in CRITICAL CARE
  • 2013-03-26. Diagnostic accuracy of early urinary index changes in differentiating transient frompersistent acute kidney injury in critically ill patients: multicenter cohortstudy in CRITICAL CARE
  • 2010-10-27. Defining prerenal azotemia in clinical practice and research in NATURE REVIEWS NEPHROLOGY
  • 2005-12-01. Evaluating mortality in intensive care units: contribution of competing risks analyses in CRITICAL CARE
  • 1996-07. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure in INTENSIVE CARE MEDICINE
  • 2015-07-09. Recovery from AKI in the critically ill: potential confounders in the evaluation in INTENSIVE CARE MEDICINE
  • 2013-01-05. Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study in INTENSIVE CARE MEDICINE
  • 2014-10-14. Three-year risk of cardiovascular disease among intensive care patients with acute kidney injury: a population-based cohort study in CRITICAL CARE
  • 2015-12-01. Evolution of chronic renal impairment and long-term mortality after de novo acute kidney injury in the critically ill; a Swedish multi-centre cohort study in CRITICAL CARE
  • 2013-05-07. Urinalysis and pre-renal acute kidney injury: time to move on in CRITICAL CARE
  • 2017-02-27. Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup in NATURE REVIEWS NEPHROLOGY
  • 2015-09-11. Defining renal recovery: pitfalls to be avoided in INTENSIVE CARE MEDICINE
  • 2004-05-24. Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group in CRITICAL CARE
  • Journal

    TITLE

    Annals of Intensive Care

    ISSUE

    1

    VOLUME

    8

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13613-018-0467-6

    DOI

    http://dx.doi.org/10.1186/s13613-018-0467-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1110711211

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30560526


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France", 
              "id": "http://www.grid.ac/institutes/grid.410529.b", 
              "name": [
                "UMR 1137 - IAME Team 5 \u2013 DeSCID : Decision SCiences in Infectious Diseases, Control and Care, Inserm/Paris Diderot University, Sorbonne Paris Cit\u00e9, Paris, France", 
                "Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France", 
                "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Truche", 
            "givenName": "A. S.", 
            "id": "sg:person.01273341045.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273341045.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Croix Rousse Hospital, Lyon University Hospital, Lyon, France", 
              "id": "http://www.grid.ac/institutes/grid.413306.3", 
              "name": [
                "Medical Intensive Care Unit, Croix Rousse Hospital, Lyon University Hospital, Lyon, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ragey", 
            "givenName": "S. Perinel", 
            "id": "sg:person.011660033653.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011660033653.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France", 
              "id": "http://www.grid.ac/institutes/grid.411163.0", 
              "name": [
                "Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Souweine", 
            "givenName": "B.", 
            "id": "sg:person.01324422064.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324422064.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France", 
              "id": "http://www.grid.ac/institutes/grid.410529.b", 
              "name": [
                "UMR 1137 - IAME Team 5 \u2013 DeSCID : Decision SCiences in Infectious Diseases, Control and Care, Inserm/Paris Diderot University, Sorbonne Paris Cit\u00e9, Paris, France", 
                "Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bailly", 
            "givenName": "S.", 
            "id": "sg:person.01125634305.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125634305.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medicine University, Paris 7 University, Paris, France", 
              "id": "http://www.grid.ac/institutes/grid.508487.6", 
              "name": [
                "Medical Intensive Care Unit, AP-HP, Saint Louis Hospital, Paris, France", 
                "Medicine University, Paris 7 University, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zafrani", 
            "givenName": "L.", 
            "id": "sg:person.01042424464.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042424464.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bouadma", 
            "givenName": "L.", 
            "id": "sg:person.01302632320.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302632320.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medicine University, Paris 13 University, Bobigny, France", 
              "id": "http://www.grid.ac/institutes/grid.11318.3a", 
              "name": [
                "Intensive Care Unit, AP-HP, Avicenne Hospital, Paris, France", 
                "Medicine University, Paris 13 University, Bobigny, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Clec\u2019h", 
            "givenName": "C.", 
            "id": "sg:person.0631007177.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631007177.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medicine University, Paris Descartes University, Sorbonne Cite, Paris, France", 
              "id": "http://www.grid.ac/institutes/grid.508487.6", 
              "name": [
                "Intensive Care Unit, Saint Joseph Hospital Network, Paris, France", 
                "Medicine University, Paris Descartes University, Sorbonne Cite, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Garrouste-Orgeas", 
            "givenName": "M.", 
            "id": "sg:person.01255251103.71", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255251103.71"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Andr\u00e9 Mignot Hospital, Versailles, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Medical Intensive Care Unit, Andr\u00e9 Mignot Hospital, Versailles, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lacave", 
            "givenName": "G.", 
            "id": "sg:person.01250226614.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250226614.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France", 
              "id": "http://www.grid.ac/institutes/grid.410529.b", 
              "name": [
                "Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schwebel", 
            "givenName": "C.", 
            "id": "sg:person.01056561220.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056561220.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France", 
              "id": "http://www.grid.ac/institutes/grid.410529.b", 
              "name": [
                "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Guebre-Egziabher", 
            "givenName": "F.", 
            "id": "sg:person.01150502675.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150502675.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Physiology Department, Cochin University Hospital, Assistance Publique, H\u00f4pitaux de Paris (AP-HP), Paris Descartes University des, Sorbonne Cite, Paris, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Physiology Department, Cochin University Hospital, Assistance Publique, H\u00f4pitaux de Paris (AP-HP), Paris Descartes University des, Sorbonne Cite, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Adrie", 
            "givenName": "C.", 
            "id": "sg:person.01172527264.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172527264.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical-Surgical Intensive Care Unit, AP-HP, Antoine B\u00e9cl\u00e8re University Hospital, Clamart, France", 
              "id": "http://www.grid.ac/institutes/grid.50550.35", 
              "name": [
                "Medical-Surgical Intensive Care Unit, AP-HP, Antoine B\u00e9cl\u00e8re University Hospital, Clamart, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dumenil", 
            "givenName": "A. S.", 
            "id": "sg:person.01027113064.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027113064.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France", 
              "id": "http://www.grid.ac/institutes/grid.410529.b", 
              "name": [
                "Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zaoui", 
            "givenName": "Ph.", 
            "id": "sg:person.01223331247.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223331247.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical Intensive Care Unit, Edouard Herriot University Hospital, Lyon, France", 
              "id": "http://www.grid.ac/institutes/grid.412180.e", 
              "name": [
                "Medical Intensive Care Unit, Edouard Herriot University Hospital, Lyon, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Argaud", 
            "givenName": "L.", 
            "id": "sg:person.01021057652.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021057652.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Critical Care Medicine Unit, Dourdan Hospital, Dourdan, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Critical Care Medicine Unit, Dourdan Hospital, Dourdan, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jamali", 
            "givenName": "S.", 
            "id": "sg:person.01167330261.78", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167330261.78"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Intensive Care Unit, Gonesse Hospital, Gonesse, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Intensive Care Unit, Gonesse Hospital, Gonesse, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goldran Toledano", 
            "givenName": "D.", 
            "id": "sg:person.01121215061.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121215061.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Surgical ICU, Edouard Herriot University Hospital, Lyon, France", 
              "id": "http://www.grid.ac/institutes/grid.412180.e", 
              "name": [
                "Surgical ICU, Edouard Herriot University Hospital, Lyon, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Marcotte", 
            "givenName": "G.", 
            "id": "sg:person.0700066673.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700066673.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "UMR 1137 - IAME Team 5 \u2013 DeSCID : Decision SCiences in Infectious Diseases, Control and Care, Inserm/Paris Diderot University, Sorbonne Paris Cit\u00e9, Paris, France", 
                "Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Timsit", 
            "givenName": "J. F.", 
            "id": "sg:person.01215000253.20", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215000253.20"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9, CRESS), INSERM, Paris, France", 
              "id": "http://www.grid.ac/institutes/grid.513249.8", 
              "name": [
                "Medical Intensive Care Unit, AP-HP, Saint Louis Hospital, Paris, France", 
                "Medicine University, Paris 7 University, Paris, France", 
                "ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9, CRESS), INSERM, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Darmon", 
            "givenName": "M.", 
            "id": "sg:person.01027641050.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027641050.35"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1186/cc5713", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042075619", 
              "https://doi.org/10.1186/cc5713"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrneph.2017.2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084129782", 
              "https://doi.org/10.1038/nrneph.2017.2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00134-015-3934-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038492356", 
              "https://doi.org/10.1007/s00134-015-3934-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrneph.2010.128", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035144056", 
              "https://doi.org/10.1038/nrneph.2010.128"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00134-012-2796-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030584096", 
              "https://doi.org/10.1007/s00134-012-2796-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2369-14-133", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050774797", 
              "https://doi.org/10.1186/1471-2369-14-133"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc11420", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006290251", 
              "https://doi.org/10.1186/cc11420"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc10327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010618652", 
              "https://doi.org/10.1186/cc10327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc10241", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041841952", 
              "https://doi.org/10.1186/cc10241"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00134-015-4033-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003653073", 
              "https://doi.org/10.1007/s00134-015-4033-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc11454", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016103624", 
              "https://doi.org/10.1186/cc11454"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13054-015-0920-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015021567", 
              "https://doi.org/10.1186/s13054-015-0920-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00134-015-3946-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014163120", 
              "https://doi.org/10.1007/s00134-015-3946-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01709751", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052044737", 
              "https://doi.org/10.1007/bf01709751"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc12582", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020722522", 
              "https://doi.org/10.1186/cc12582"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc3921", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004657384", 
              "https://doi.org/10.1186/cc3921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc2872", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031071552", 
              "https://doi.org/10.1186/cc2872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc6852", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039041362", 
              "https://doi.org/10.1186/cc6852"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/cc12676", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019529569", 
              "https://doi.org/10.1186/cc12676"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13054-014-0492-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039703379", 
              "https://doi.org/10.1186/s13054-014-0492-2"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-12-17", 
        "datePublishedReg": "2018-12-17", 
        "description": "BackgroundTransient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.DesignRetrospective analysis of a prospective database via cause-specific model, with 28-day ICU mortality as primary end point, considering discharge alive as a competing event and taking into account time-dependent nature of renal recovery. Renal recovery was defined as a decrease of at least one KDIGO class compared to the previous day.Setting23 French ICUs.PatientsPatients of a French multicentric observational cohort were included if they suffered from AKI at ICU admission between 1996 and 2015.InterventionNone.ResultsA total of 5242 patients were included. Initial severity according to KDIGO creatinine definition was AKI stage 1 for 2458 patients (46.89%), AKI stage 2 for 1181 (22.53%) and AKI stage 3 for 1603 (30.58%). Crude 28-day ICU mortality according to AKI severity was 22.74% (n\u2009=\u2009559), 27.69% (n\u2009=\u2009327) and 26.26% (n\u2009=\u2009421), respectively. Renal recovery was experienced by 3085 patients (58.85%), and its rate was significantly different between AKI severity stages (P\u2009<\u20090.01). Twenty-eight-day ICU mortality was independently lower in patients experiencing renal recovery [CSHR 0.54 (95% CI 0.46\u20130.63), P\u2009<\u20090.01]. Lastly, RRT requirement was strongly associated with persistent AKI whichever threshold was chosen between day 2 and 7 to delineate transient from persistent AKI.ConclusionsShort-term renal recovery, according to several definitions, was independently associated with higher mortality and RRT requirement. Moreover, distinction between transient and persistent AKI is consequently a clinically relevant surrogate outcome variable for diagnostic testing in critically ill patients.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/s13613-018-0467-6", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1045300", 
            "issn": [
              "2110-5820"
            ], 
            "name": "Annals of Intensive Care", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "8"
          }
        ], 
        "keywords": [
          "persistent acute kidney injury", 
          "acute kidney injury", 
          "renal recovery", 
          "ICU mortality", 
          "AKI duration", 
          "RRT requirement", 
          "ill patients", 
          "AKI stage 1", 
          "AKI stage 2", 
          "AKI stage 3", 
          "AKI severity stage", 
          "primary end point", 
          "renal replacement therapy", 
          "cause-specific model", 
          "surrogate outcome variable", 
          "DesignRetrospective analysis", 
          "AKI severity", 
          "kidney injury", 
          "ICU admission", 
          "prospective database", 
          "ICU survival", 
          "prognostic impact", 
          "observational cohort", 
          "ResultsA total", 
          "replacement therapy", 
          "initial severity", 
          "physiopathological mechanisms", 
          "severity stages", 
          "patients", 
          "day 2", 
          "high mortality", 
          "diagnostic testing", 
          "end point", 
          "mortality", 
          "outcome variables", 
          "stage 3", 
          "stage 1", 
          "stage 2", 
          "severity", 
          "duration", 
          "previous day", 
          "PatientsPatients", 
          "admission", 
          "injury", 
          "therapy", 
          "recovery", 
          "cohort", 
          "survival", 
          "total", 
          "days", 
          "discharge", 
          "decrease", 
          "testing", 
          "database", 
          "study", 
          "rate", 
          "events", 
          "objective", 
          "mechanism", 
          "need", 
          "stage", 
          "threshold", 
          "definition", 
          "variables", 
          "time-dependent nature", 
          "impact", 
          "analysis", 
          "point", 
          "model", 
          "respect", 
          "requirements", 
          "distinction", 
          "class", 
          "nature"
        ], 
        "name": "ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients", 
        "pagination": "127", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1110711211"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s13613-018-0467-6"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30560526"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s13613-018-0467-6", 
          "https://app.dimensions.ai/details/publication/pub.1110711211"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T16:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_791.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/s13613-018-0467-6"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0467-6'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0467-6'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0467-6'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-018-0467-6'


     

    This table displays all metadata directly associated to this object as RDF triples.

    392 TRIPLES      21 PREDICATES      119 URIs      91 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s13613-018-0467-6 schema:about anzsrc-for:11
    2 anzsrc-for:1103
    3 schema:author N2ab6a7967ddb44bd94b070126feb53ca
    4 schema:citation sg:pub.10.1007/bf01709751
    5 sg:pub.10.1007/s00134-012-2796-5
    6 sg:pub.10.1007/s00134-015-3934-7
    7 sg:pub.10.1007/s00134-015-3946-3
    8 sg:pub.10.1007/s00134-015-4033-5
    9 sg:pub.10.1038/nrneph.2010.128
    10 sg:pub.10.1038/nrneph.2017.2
    11 sg:pub.10.1186/1471-2369-14-133
    12 sg:pub.10.1186/cc10241
    13 sg:pub.10.1186/cc10327
    14 sg:pub.10.1186/cc11420
    15 sg:pub.10.1186/cc11454
    16 sg:pub.10.1186/cc12582
    17 sg:pub.10.1186/cc12676
    18 sg:pub.10.1186/cc2872
    19 sg:pub.10.1186/cc3921
    20 sg:pub.10.1186/cc5713
    21 sg:pub.10.1186/cc6852
    22 sg:pub.10.1186/s13054-014-0492-2
    23 sg:pub.10.1186/s13054-015-0920-y
    24 schema:datePublished 2018-12-17
    25 schema:datePublishedReg 2018-12-17
    26 schema:description BackgroundTransient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.DesignRetrospective analysis of a prospective database via cause-specific model, with 28-day ICU mortality as primary end point, considering discharge alive as a competing event and taking into account time-dependent nature of renal recovery. Renal recovery was defined as a decrease of at least one KDIGO class compared to the previous day.Setting23 French ICUs.PatientsPatients of a French multicentric observational cohort were included if they suffered from AKI at ICU admission between 1996 and 2015.InterventionNone.ResultsA total of 5242 patients were included. Initial severity according to KDIGO creatinine definition was AKI stage 1 for 2458 patients (46.89%), AKI stage 2 for 1181 (22.53%) and AKI stage 3 for 1603 (30.58%). Crude 28-day ICU mortality according to AKI severity was 22.74% (n = 559), 27.69% (n = 327) and 26.26% (n = 421), respectively. Renal recovery was experienced by 3085 patients (58.85%), and its rate was significantly different between AKI severity stages (P < 0.01). Twenty-eight-day ICU mortality was independently lower in patients experiencing renal recovery [CSHR 0.54 (95% CI 0.46–0.63), P < 0.01]. Lastly, RRT requirement was strongly associated with persistent AKI whichever threshold was chosen between day 2 and 7 to delineate transient from persistent AKI.ConclusionsShort-term renal recovery, according to several definitions, was independently associated with higher mortality and RRT requirement. Moreover, distinction between transient and persistent AKI is consequently a clinically relevant surrogate outcome variable for diagnostic testing in critically ill patients.
    27 schema:genre article
    28 schema:isAccessibleForFree true
    29 schema:isPartOf N5b23a6ed1fba44e4af0f4392371bd219
    30 Nc8cd3417eb0646d2820f1298e6583a31
    31 sg:journal.1045300
    32 schema:keywords AKI duration
    33 AKI severity
    34 AKI severity stage
    35 AKI stage 1
    36 AKI stage 2
    37 AKI stage 3
    38 DesignRetrospective analysis
    39 ICU admission
    40 ICU mortality
    41 ICU survival
    42 PatientsPatients
    43 RRT requirement
    44 ResultsA total
    45 acute kidney injury
    46 admission
    47 analysis
    48 cause-specific model
    49 class
    50 cohort
    51 database
    52 day 2
    53 days
    54 decrease
    55 definition
    56 diagnostic testing
    57 discharge
    58 distinction
    59 duration
    60 end point
    61 events
    62 high mortality
    63 ill patients
    64 impact
    65 initial severity
    66 injury
    67 kidney injury
    68 mechanism
    69 model
    70 mortality
    71 nature
    72 need
    73 objective
    74 observational cohort
    75 outcome variables
    76 patients
    77 persistent acute kidney injury
    78 physiopathological mechanisms
    79 point
    80 previous day
    81 primary end point
    82 prognostic impact
    83 prospective database
    84 rate
    85 recovery
    86 renal recovery
    87 renal replacement therapy
    88 replacement therapy
    89 requirements
    90 respect
    91 severity
    92 severity stages
    93 stage
    94 stage 1
    95 stage 2
    96 stage 3
    97 study
    98 surrogate outcome variable
    99 survival
    100 testing
    101 therapy
    102 threshold
    103 time-dependent nature
    104 total
    105 variables
    106 schema:name ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients
    107 schema:pagination 127
    108 schema:productId N020a05c2cb404e3ea1a88f90c113268b
    109 N64beda36638041169514e4a5827e8f0b
    110 N9644a2813ee446d6af82385f6d3b41d1
    111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110711211
    112 https://doi.org/10.1186/s13613-018-0467-6
    113 schema:sdDatePublished 2022-09-02T16:03
    114 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    115 schema:sdPublisher Nbe3bef734b9a4960a516c503d17c498f
    116 schema:url https://doi.org/10.1186/s13613-018-0467-6
    117 sgo:license sg:explorer/license/
    118 sgo:sdDataset articles
    119 rdf:type schema:ScholarlyArticle
    120 N020a05c2cb404e3ea1a88f90c113268b schema:name doi
    121 schema:value 10.1186/s13613-018-0467-6
    122 rdf:type schema:PropertyValue
    123 N0286ed11a38948688be4947d4dbaf984 rdf:first sg:person.01302632320.41
    124 rdf:rest Nd8d40b61211149e698e148e827b50b5f
    125 N20df531841fc4799ad1de9c5d6c00a3a rdf:first sg:person.01125634305.00
    126 rdf:rest N6cbfcd2ef856435fa354ecb97fe5aaa9
    127 N257a6e9da9f44bec8ae772dfc5681513 rdf:first sg:person.01324422064.31
    128 rdf:rest N20df531841fc4799ad1de9c5d6c00a3a
    129 N2ab6a7967ddb44bd94b070126feb53ca rdf:first sg:person.01273341045.96
    130 rdf:rest Na6c7862dc44445988ac931a57911a263
    131 N3b36222efa884f1da718b1168b30e4de rdf:first sg:person.01250226614.55
    132 rdf:rest N4e55777cf9cd4986ad28752438925516
    133 N3ca694c9092046e1804616049bcfcb78 rdf:first sg:person.01027641050.35
    134 rdf:rest rdf:nil
    135 N4c056a3078714820a9b2f37eb376f6c2 rdf:first sg:person.01167330261.78
    136 rdf:rest Nb1c5a27f4b874527a4fb39ae0c396541
    137 N4c83143f12dd4d2796f16ff52fc48dc7 rdf:first sg:person.01223331247.16
    138 rdf:rest N4ed2a5876c95455ba1a7166fd818c1fd
    139 N4e55777cf9cd4986ad28752438925516 rdf:first sg:person.01056561220.01
    140 rdf:rest N96a4a3c1624c407ead62929755a035a2
    141 N4ed2a5876c95455ba1a7166fd818c1fd rdf:first sg:person.01021057652.80
    142 rdf:rest N4c056a3078714820a9b2f37eb376f6c2
    143 N59c9fe83fc754679993db48657f94ad9 rdf:first sg:person.01215000253.20
    144 rdf:rest N3ca694c9092046e1804616049bcfcb78
    145 N5b23a6ed1fba44e4af0f4392371bd219 schema:issueNumber 1
    146 rdf:type schema:PublicationIssue
    147 N64beda36638041169514e4a5827e8f0b schema:name dimensions_id
    148 schema:value pub.1110711211
    149 rdf:type schema:PropertyValue
    150 N6cbfcd2ef856435fa354ecb97fe5aaa9 rdf:first sg:person.01042424464.15
    151 rdf:rest N0286ed11a38948688be4947d4dbaf984
    152 N9644a2813ee446d6af82385f6d3b41d1 schema:name pubmed_id
    153 schema:value 30560526
    154 rdf:type schema:PropertyValue
    155 N96a4a3c1624c407ead62929755a035a2 rdf:first sg:person.01150502675.56
    156 rdf:rest Nce48a0b6ad03478ea125c5ff4ea2653a
    157 Na6c7862dc44445988ac931a57911a263 rdf:first sg:person.011660033653.17
    158 rdf:rest N257a6e9da9f44bec8ae772dfc5681513
    159 Nae5e6eae9ed44e6f9c4a21a558ab64ec rdf:first sg:person.0700066673.74
    160 rdf:rest N59c9fe83fc754679993db48657f94ad9
    161 Nb1c5a27f4b874527a4fb39ae0c396541 rdf:first sg:person.01121215061.42
    162 rdf:rest Nae5e6eae9ed44e6f9c4a21a558ab64ec
    163 Nbe3bef734b9a4960a516c503d17c498f schema:name Springer Nature - SN SciGraph project
    164 rdf:type schema:Organization
    165 Nc8cd3417eb0646d2820f1298e6583a31 schema:volumeNumber 8
    166 rdf:type schema:PublicationVolume
    167 Nce48a0b6ad03478ea125c5ff4ea2653a rdf:first sg:person.01172527264.26
    168 rdf:rest Nee042e0d8b5242e3b67be419a211528b
    169 Nd7ca27bc1a0e4fa7906228c676e677e1 rdf:first sg:person.01255251103.71
    170 rdf:rest N3b36222efa884f1da718b1168b30e4de
    171 Nd8d40b61211149e698e148e827b50b5f rdf:first sg:person.0631007177.42
    172 rdf:rest Nd7ca27bc1a0e4fa7906228c676e677e1
    173 Nee042e0d8b5242e3b67be419a211528b rdf:first sg:person.01027113064.83
    174 rdf:rest N4c83143f12dd4d2796f16ff52fc48dc7
    175 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    176 schema:name Medical and Health Sciences
    177 rdf:type schema:DefinedTerm
    178 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    179 schema:name Clinical Sciences
    180 rdf:type schema:DefinedTerm
    181 sg:journal.1045300 schema:issn 2110-5820
    182 schema:name Annals of Intensive Care
    183 schema:publisher Springer Nature
    184 rdf:type schema:Periodical
    185 sg:person.01021057652.80 schema:affiliation grid-institutes:grid.412180.e
    186 schema:familyName Argaud
    187 schema:givenName L.
    188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021057652.80
    189 rdf:type schema:Person
    190 sg:person.01027113064.83 schema:affiliation grid-institutes:grid.50550.35
    191 schema:familyName Dumenil
    192 schema:givenName A. S.
    193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027113064.83
    194 rdf:type schema:Person
    195 sg:person.01027641050.35 schema:affiliation grid-institutes:grid.513249.8
    196 schema:familyName Darmon
    197 schema:givenName M.
    198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027641050.35
    199 rdf:type schema:Person
    200 sg:person.01042424464.15 schema:affiliation grid-institutes:grid.508487.6
    201 schema:familyName Zafrani
    202 schema:givenName L.
    203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042424464.15
    204 rdf:type schema:Person
    205 sg:person.01056561220.01 schema:affiliation grid-institutes:grid.410529.b
    206 schema:familyName Schwebel
    207 schema:givenName C.
    208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056561220.01
    209 rdf:type schema:Person
    210 sg:person.01121215061.42 schema:affiliation grid-institutes:None
    211 schema:familyName Goldran Toledano
    212 schema:givenName D.
    213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121215061.42
    214 rdf:type schema:Person
    215 sg:person.01125634305.00 schema:affiliation grid-institutes:grid.410529.b
    216 schema:familyName Bailly
    217 schema:givenName S.
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125634305.00
    219 rdf:type schema:Person
    220 sg:person.01150502675.56 schema:affiliation grid-institutes:grid.410529.b
    221 schema:familyName Guebre-Egziabher
    222 schema:givenName F.
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150502675.56
    224 rdf:type schema:Person
    225 sg:person.011660033653.17 schema:affiliation grid-institutes:grid.413306.3
    226 schema:familyName Ragey
    227 schema:givenName S. Perinel
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011660033653.17
    229 rdf:type schema:Person
    230 sg:person.01167330261.78 schema:affiliation grid-institutes:None
    231 schema:familyName Jamali
    232 schema:givenName S.
    233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167330261.78
    234 rdf:type schema:Person
    235 sg:person.01172527264.26 schema:affiliation grid-institutes:None
    236 schema:familyName Adrie
    237 schema:givenName C.
    238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172527264.26
    239 rdf:type schema:Person
    240 sg:person.01215000253.20 schema:affiliation grid-institutes:None
    241 schema:familyName Timsit
    242 schema:givenName J. F.
    243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215000253.20
    244 rdf:type schema:Person
    245 sg:person.01223331247.16 schema:affiliation grid-institutes:grid.410529.b
    246 schema:familyName Zaoui
    247 schema:givenName Ph.
    248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223331247.16
    249 rdf:type schema:Person
    250 sg:person.01250226614.55 schema:affiliation grid-institutes:None
    251 schema:familyName Lacave
    252 schema:givenName G.
    253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250226614.55
    254 rdf:type schema:Person
    255 sg:person.01255251103.71 schema:affiliation grid-institutes:grid.508487.6
    256 schema:familyName Garrouste-Orgeas
    257 schema:givenName M.
    258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255251103.71
    259 rdf:type schema:Person
    260 sg:person.01273341045.96 schema:affiliation grid-institutes:grid.410529.b
    261 schema:familyName Truche
    262 schema:givenName A. S.
    263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273341045.96
    264 rdf:type schema:Person
    265 sg:person.01302632320.41 schema:affiliation grid-institutes:None
    266 schema:familyName Bouadma
    267 schema:givenName L.
    268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302632320.41
    269 rdf:type schema:Person
    270 sg:person.01324422064.31 schema:affiliation grid-institutes:grid.411163.0
    271 schema:familyName Souweine
    272 schema:givenName B.
    273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324422064.31
    274 rdf:type schema:Person
    275 sg:person.0631007177.42 schema:affiliation grid-institutes:grid.11318.3a
    276 schema:familyName Clec’h
    277 schema:givenName C.
    278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631007177.42
    279 rdf:type schema:Person
    280 sg:person.0700066673.74 schema:affiliation grid-institutes:grid.412180.e
    281 schema:familyName Marcotte
    282 schema:givenName G.
    283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700066673.74
    284 rdf:type schema:Person
    285 sg:pub.10.1007/bf01709751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052044737
    286 https://doi.org/10.1007/bf01709751
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1007/s00134-012-2796-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030584096
    289 https://doi.org/10.1007/s00134-012-2796-5
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1007/s00134-015-3934-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038492356
    292 https://doi.org/10.1007/s00134-015-3934-7
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1007/s00134-015-3946-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014163120
    295 https://doi.org/10.1007/s00134-015-3946-3
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1007/s00134-015-4033-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003653073
    298 https://doi.org/10.1007/s00134-015-4033-5
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1038/nrneph.2010.128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035144056
    301 https://doi.org/10.1038/nrneph.2010.128
    302 rdf:type schema:CreativeWork
    303 sg:pub.10.1038/nrneph.2017.2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084129782
    304 https://doi.org/10.1038/nrneph.2017.2
    305 rdf:type schema:CreativeWork
    306 sg:pub.10.1186/1471-2369-14-133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050774797
    307 https://doi.org/10.1186/1471-2369-14-133
    308 rdf:type schema:CreativeWork
    309 sg:pub.10.1186/cc10241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041841952
    310 https://doi.org/10.1186/cc10241
    311 rdf:type schema:CreativeWork
    312 sg:pub.10.1186/cc10327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010618652
    313 https://doi.org/10.1186/cc10327
    314 rdf:type schema:CreativeWork
    315 sg:pub.10.1186/cc11420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006290251
    316 https://doi.org/10.1186/cc11420
    317 rdf:type schema:CreativeWork
    318 sg:pub.10.1186/cc11454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016103624
    319 https://doi.org/10.1186/cc11454
    320 rdf:type schema:CreativeWork
    321 sg:pub.10.1186/cc12582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020722522
    322 https://doi.org/10.1186/cc12582
    323 rdf:type schema:CreativeWork
    324 sg:pub.10.1186/cc12676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019529569
    325 https://doi.org/10.1186/cc12676
    326 rdf:type schema:CreativeWork
    327 sg:pub.10.1186/cc2872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031071552
    328 https://doi.org/10.1186/cc2872
    329 rdf:type schema:CreativeWork
    330 sg:pub.10.1186/cc3921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004657384
    331 https://doi.org/10.1186/cc3921
    332 rdf:type schema:CreativeWork
    333 sg:pub.10.1186/cc5713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042075619
    334 https://doi.org/10.1186/cc5713
    335 rdf:type schema:CreativeWork
    336 sg:pub.10.1186/cc6852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039041362
    337 https://doi.org/10.1186/cc6852
    338 rdf:type schema:CreativeWork
    339 sg:pub.10.1186/s13054-014-0492-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039703379
    340 https://doi.org/10.1186/s13054-014-0492-2
    341 rdf:type schema:CreativeWork
    342 sg:pub.10.1186/s13054-015-0920-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1015021567
    343 https://doi.org/10.1186/s13054-015-0920-y
    344 rdf:type schema:CreativeWork
    345 grid-institutes:None schema:alternateName Critical Care Medicine Unit, Dourdan Hospital, Dourdan, France
    346 Intensive Care Unit, Gonesse Hospital, Gonesse, France
    347 Medical Intensive Care Unit, André Mignot Hospital, Versailles, France
    348 Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France
    349 Physiology Department, Cochin University Hospital, Assistance Publique, Hôpitaux de Paris (AP-HP), Paris Descartes University des, Sorbonne Cite, Paris, France
    350 schema:name Critical Care Medicine Unit, Dourdan Hospital, Dourdan, France
    351 Intensive Care Unit, Gonesse Hospital, Gonesse, France
    352 Medical Intensive Care Unit, André Mignot Hospital, Versailles, France
    353 Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat Hospital, Paris Diderot University, 75018, Paris, France
    354 Physiology Department, Cochin University Hospital, Assistance Publique, Hôpitaux de Paris (AP-HP), Paris Descartes University des, Sorbonne Cite, Paris, France
    355 UMR 1137 - IAME Team 5 – DeSCID : Decision SCiences in Infectious Diseases, Control and Care, Inserm/Paris Diderot University, Sorbonne Paris Cité, Paris, France
    356 rdf:type schema:Organization
    357 grid-institutes:grid.11318.3a schema:alternateName Medicine University, Paris 13 University, Bobigny, France
    358 schema:name Intensive Care Unit, AP-HP, Avicenne Hospital, Paris, France
    359 Medicine University, Paris 13 University, Bobigny, France
    360 rdf:type schema:Organization
    361 grid-institutes:grid.410529.b schema:alternateName Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France
    362 Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France
    363 schema:name Medical Intensive Care Unit, Grenoble University Hospital, Grenoble 1 University, U823, La Tronche, France
    364 Nephrology Dialysis Renal Transplantation, Grenoble University Hospital, La Tronche, France
    365 UMR 1137 - IAME Team 5 – DeSCID : Decision SCiences in Infectious Diseases, Control and Care, Inserm/Paris Diderot University, Sorbonne Paris Cité, Paris, France
    366 rdf:type schema:Organization
    367 grid-institutes:grid.411163.0 schema:alternateName Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France
    368 schema:name Medical Intensive Care Unit, Gabriel Montpied University Hospital, Clermont-Ferrand, France
    369 rdf:type schema:Organization
    370 grid-institutes:grid.412180.e schema:alternateName Medical Intensive Care Unit, Edouard Herriot University Hospital, Lyon, France
    371 Surgical ICU, Edouard Herriot University Hospital, Lyon, France
    372 schema:name Medical Intensive Care Unit, Edouard Herriot University Hospital, Lyon, France
    373 Surgical ICU, Edouard Herriot University Hospital, Lyon, France
    374 rdf:type schema:Organization
    375 grid-institutes:grid.413306.3 schema:alternateName Medical Intensive Care Unit, Croix Rousse Hospital, Lyon University Hospital, Lyon, France
    376 schema:name Medical Intensive Care Unit, Croix Rousse Hospital, Lyon University Hospital, Lyon, France
    377 rdf:type schema:Organization
    378 grid-institutes:grid.50550.35 schema:alternateName Medical-Surgical Intensive Care Unit, AP-HP, Antoine Béclère University Hospital, Clamart, France
    379 schema:name Medical-Surgical Intensive Care Unit, AP-HP, Antoine Béclère University Hospital, Clamart, France
    380 rdf:type schema:Organization
    381 grid-institutes:grid.508487.6 schema:alternateName Medicine University, Paris 7 University, Paris, France
    382 Medicine University, Paris Descartes University, Sorbonne Cite, Paris, France
    383 schema:name Intensive Care Unit, Saint Joseph Hospital Network, Paris, France
    384 Medical Intensive Care Unit, AP-HP, Saint Louis Hospital, Paris, France
    385 Medicine University, Paris 7 University, Paris, France
    386 Medicine University, Paris Descartes University, Sorbonne Cite, Paris, France
    387 rdf:type schema:Organization
    388 grid-institutes:grid.513249.8 schema:alternateName ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris, France
    389 schema:name ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris, France
    390 Medical Intensive Care Unit, AP-HP, Saint Louis Hospital, Paris, France
    391 Medicine University, Paris 7 University, Paris, France
    392 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...