Ontology type: schema:ScholarlyArticle Open Access: True
2018-12
AUTHORSMohammed S. Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al-Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Alraddadi, Kim Lewis, Mohammed Badawee, Yaseen M. Arabi, Eddy Fan, Waleed Alhazzani
ABSTRACTBACKGROUND: Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy in severely hypoxemic patients who failed conventional strategies. METHODS: We collected data retrospectively on MERS-CoV patients with refractory respiratory failure from April 2014 to December 2015 in 5 intensive care units (ICUs) in Saudi Arabia. Patients were classified into two groups: ECMO versus conventional therapy. Our primary outcome was in-hospital mortality; secondary outcomes included ICU and hospital length of stay. RESULTS: Thirty-five patients were included; 17 received ECMO and 18 received conventional therapy. Both groups had similar baseline characteristics. The ECMO group had lower in-hospital mortality (65 vs. 100%, P = 0.02), longer ICU stay (median 25 vs. 8 days, respectively, P < 0.01), and similar hospital stay (median 41 vs. 31 days, P = 0.421). In addition, patients in the ECMO group had better PaO2/FiO2 at days 7 and 14 of admission to the ICU (124 vs. 63, and 138 vs. 36, P < 0.05), and less use of norepinephrine at days 1 and 14 (29 vs. 80%; and 36 vs. 93%, P < 0.05). CONCLUSIONS: ECMO use, as a rescue therapy, was associated with lower mortality in MERS patients with refractory hypoxemia. The results of this, largest to date, support the use of ECMO as a rescue therapy in patients with severe MERS-CoV. More... »
PAGES3
http://scigraph.springernature.com/pub.10.1186/s13613-017-0350-x
DOIhttp://dx.doi.org/10.1186/s13613-017-0350-x
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29330690
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"description": "BACKGROUND: Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy in severely hypoxemic patients who failed conventional strategies.\nMETHODS: We collected data retrospectively on MERS-CoV patients with refractory respiratory failure from April 2014 to December 2015 in 5 intensive care units (ICUs) in Saudi Arabia. Patients were classified into two groups: ECMO versus conventional therapy. Our primary outcome was in-hospital mortality; secondary outcomes included ICU and hospital length of stay.\nRESULTS: Thirty-five patients were included; 17 received ECMO and 18 received conventional therapy. Both groups had similar baseline characteristics. The ECMO group had lower in-hospital mortality (65 vs. 100%, P\u00a0=\u00a00.02), longer ICU stay (median 25 vs. 8\u00a0days, respectively, P\u00a0<\u00a00.01), and similar hospital stay (median 41 vs. 31\u00a0days, P\u00a0=\u00a00.421). In addition, patients in the ECMO group had better PaO2/FiO2 at days 7 and 14 of admission to the ICU (124 vs. 63, and 138 vs. 36, P\u00a0<\u00a00.05), and less use of norepinephrine at days 1 and 14 (29 vs. 80%; and 36 vs. 93%, P\u00a0<\u00a00.05).\nCONCLUSIONS: ECMO use, as a rescue therapy, was associated with lower mortality in MERS patients with refractory hypoxemia. The results of this, largest to date, support the use of ECMO as a rescue therapy in patients with severe MERS-CoV.",
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]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29330690"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101562873"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13613-017-0350-x"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1100279455"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13613-017-0350-x",
"https://app.dimensions.ai/details/publication/pub.1100279455"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T16:38",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000493.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1186/s13613-017-0350-x"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0350-x'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0350-x'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0350-x'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0350-x'
This table displays all metadata directly associated to this object as RDF triples.
356 TRIPLES
21 PREDICATES
64 URIs
21 LITERALS
9 BLANK NODES