Patients with ANCA-associated vasculitis admitted to the intensive care unit with acute vasculitis manifestations: a retrospective and comparative multicentric study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Julien Demiselle, Johann Auchabie, François Beloncle, Philippe Gatault, Steven Grangé, Damien Du Cheyron, Jean Dellamonica, Sonia Boyer, Dimitri Titeca Beauport, Lise Piquilloud, Julien Letheulle, Christophe Guitton, Nicolas Chudeau, Guillaume Geri, François Fourrier, René Robert, Emmanuel Guérot, Julie Boisramé-Helms, Pierre Galichon, Pierre-François Dequin, Alexandre Lautrette, Pierre-Edouard Bollaert, Ferhat Meziani, Loïc Guillevin, Nicolas Lerolle, Jean-François Augusto

ABSTRACT

PURPOSE: Data for ANCA-associated vasculitis (AAV) patients requiring intensive care are scarce. METHODS: We included 97 consecutive patients with acute AAV manifestations (new onset or relapsing disease), admitted to 18 intensive care units (ICUs) over a 10-year period (2002-2012). A group of 95 consecutive AAV patients with new onset or relapsing disease, admitted to two nephrology departments with acute vasculitis manifestations, constituted the control group. RESULTS: In the ICU group, patients predominantly showed granulomatosis with polyangiitis and proteinase-3 ANCAs. Compared with the non-ICU group, the ICU group showed comparable Birmingham vasculitis activity score and a higher frequency of heart, central nervous system and lungs involvements. Respiratory assistance, renal replacement therapy and vasopressors were required in 68.0, 56.7 and 26.8% of ICU patients, respectively. All but one patient (99%) received glucocorticoids, 85.6% received cyclophosphamide, and 49.5% had plasma exchanges as remission induction regimens. Fifteen (15.5%) patients died during the ICU stay. The following were significantly associated with ICU mortality in the univariate analysis: the need for respiratory assistance, the use of vasopressors, the occurrence of at least one infection event in ICU, cyclophosphamide treatment, sequential organ failure assessment at admission and simplified acute physiology score II. After adjustment on sequential organ failure assessment or infection, cyclophosphamide was no longer a risk factor for mortality. Despite a higher initial mortality rate of ICU patients within the first hospital stay (p < 0.0001), the long-term mortality of hospital survivors did not differ between ICU and non-ICU groups (18.6 and 20.4%, respectively, p = 0.36). Moreover, we observed no renal survival difference between groups after a 1-year follow-up (82.1 and 80.5%, p = 0.94). CONCLUSION: This study supports the idea that experiencing an ICU challenge does not impact the long-term prognosis of AAV patients. More... »

PAGES

39

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13613-017-0262-9

DOI

http://dx.doi.org/10.1186/s13613-017-0262-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084612633

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28382598


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Angers", 
          "id": "https://www.grid.ac/institutes/grid.411147.6", 
          "name": [
            "D\u00e9partement de R\u00e9animation M\u00e9dicale et de M\u00e9decine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France", 
            "N\u00e9phrologie-Dialyse-Transplantation, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Demiselle", 
        "givenName": "Julien", 
        "id": "sg:person.01044311411.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044311411.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "D\u00e9partement de R\u00e9animation M\u00e9dicale et de M\u00e9decine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Auchabie", 
        "givenName": "Johann", 
        "id": "sg:person.016427405013.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016427405013.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "D\u00e9partement de R\u00e9animation M\u00e9dicale et de M\u00e9decine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beloncle", 
        "givenName": "Fran\u00e7ois", 
        "id": "sg:person.01331205526.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331205526.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Tours", 
          "id": "https://www.grid.ac/institutes/grid.411167.4", 
          "name": [
            "Service de N\u00e9phrologie et Immunologie Clinique, CHRU Tours, Tours, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gatault", 
        "givenName": "Philippe", 
        "id": "sg:person.01057177611.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057177611.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire De Rouen", 
          "id": "https://www.grid.ac/institutes/grid.41724.34", 
          "name": [
            "Medical Intensive Care Unit, Rouen University Hospital, Rouen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grang\u00e9", 
        "givenName": "Steven", 
        "id": "sg:person.01126264407.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126264407.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Caen", 
          "id": "https://www.grid.ac/institutes/grid.411149.8", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, CHU de Caen, Avenue de la C\u00f4te de Nacre, CS 30001, 14033, Caen Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Du Cheyron", 
        "givenName": "Damien", 
        "id": "sg:person.0676137344.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676137344.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Medical Intensive Care Unit, Archet 1 University Hospital, Route de St Antoine, CS 23079, 06202, Nice, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dellamonica", 
        "givenName": "Jean", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Medical Intensive Care Unit, Archet 1 University Hospital, Route de St Antoine, CS 23079, 06202, Nice, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boyer", 
        "givenName": "Sonia", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire D' Amiens", 
          "id": "https://www.grid.ac/institutes/grid.134996.0", 
          "name": [
            "Medical Intensive Care Unit, Amiens University Medical Center, 80054, Amiens, Cedex 1, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beauport", 
        "givenName": "Dimitri Titeca", 
        "id": "sg:person.015707336553.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015707336553.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital of Lausanne", 
          "id": "https://www.grid.ac/institutes/grid.8515.9", 
          "name": [
            "D\u00e9partement de R\u00e9animation M\u00e9dicale et de M\u00e9decine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France", 
            "Service de M\u00e9decine Intensive Adulte et Centre des Br\u00fbl\u00e9s, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Piquilloud", 
        "givenName": "Lise", 
        "id": "sg:person.01237332505.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237332505.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "l'H\u00f4pital Pontchaillou", 
          "id": "https://www.grid.ac/institutes/grid.414271.5", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Pontchaillou, CHU Rennes, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Letheulle", 
        "givenName": "Julien", 
        "id": "sg:person.0736551220.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736551220.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "D\u00e9l\u00e9gation Grand-Ouest", 
          "id": "https://www.grid.ac/institutes/grid.457374.6", 
          "name": [
            "Medical Intensive Care Unit, H\u00f4tel-Dieu, University Hospital of Nantes, 30 bd Jean Monnet, 44093, Nantes, France", 
            "UMR 1064, Inserm, 30 bd Jean Monnet, 44093, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guitton", 
        "givenName": "Christophe", 
        "id": "sg:person.01350000735.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350000735.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier du Mans", 
          "id": "https://www.grid.ac/institutes/grid.418061.a", 
          "name": [
            "Service de Reanimation Medico-Chirurgicale, Centre Hospitalier du Mans, 194 Avenue Rubillard, 72037, Le Mans, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chudeau", 
        "givenName": "Nicolas", 
        "id": "sg:person.01076605442.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076605442.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Cochin", 
          "id": "https://www.grid.ac/institutes/grid.411784.f", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Cochin, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Geri", 
        "givenName": "Guillaume", 
        "id": "sg:person.01332405102.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332405102.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Roger Salengro", 
          "id": "https://www.grid.ac/institutes/grid.414293.9", 
          "name": [
            "R\u00e9animation, Centre de R\u00e9animation Polyvalente, H\u00f4pital Roger Salengro, CHRU de Lille, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fourrier", 
        "givenName": "Fran\u00e7ois", 
        "id": "sg:person.01171472721.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171472721.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Poitiers", 
          "id": "https://www.grid.ac/institutes/grid.411162.1", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, CHU de Poitiers, Poitiers, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robert", 
        "givenName": "Ren\u00e9", 
        "id": "sg:person.0724071106.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724071106.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gu\u00e9rot", 
        "givenName": "Emmanuel", 
        "id": "sg:person.01327536175.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327536175.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Strasbourg", 
          "id": "https://www.grid.ac/institutes/grid.11843.3f", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, Nouvel H\u00f4pital Civil, H\u00f4pitaux Universitaires de Strasbourg, Strasbourg, France", 
            "EA 7293, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS), Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Strasbourg, Strasbourg, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boisram\u00e9-Helms", 
        "givenName": "Julie", 
        "id": "sg:person.01046537257.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046537257.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "APHP, H\u00f4pital Tenon, Urgences N\u00e9phrologiques et Transplantation R\u00e9nale, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Galichon", 
        "givenName": "Pierre", 
        "id": "sg:person.0730060155.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730060155.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bretonneau Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411777.3", 
          "name": [
            "Service de R\u00e9animation Polyvalente, H\u00f4pital Bretonneau, Tours, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dequin", 
        "givenName": "Pierre-Fran\u00e7ois", 
        "id": "sg:person.01017110566.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017110566.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Clermont-Ferrand", 
          "id": "https://www.grid.ac/institutes/grid.411163.0", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale Polyvalente, CHU Gabriel Montpied, 58 rue Montalembert, 63000, Clermont-Ferrand, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lautrette", 
        "givenName": "Alexandre", 
        "id": "sg:person.01116303100.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116303100.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, CHU de Nancy H\u00f4pital Central, 29 Avenue de Lattre de Tassigny, 54035, Nancy Cedex, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bollaert", 
        "givenName": "Pierre-Edouard", 
        "id": "sg:person.01101663440.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101663440.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Strasbourg", 
          "id": "https://www.grid.ac/institutes/grid.11843.3f", 
          "name": [
            "Service de R\u00e9animation M\u00e9dicale, Nouvel H\u00f4pital Civil, H\u00f4pitaux Universitaires de Strasbourg, Strasbourg, France", 
            "EA 7293, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS), Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Strasbourg, Strasbourg, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meziani", 
        "givenName": "Ferhat", 
        "id": "sg:person.0633723234.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633723234.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Cochin", 
          "id": "https://www.grid.ac/institutes/grid.411784.f", 
          "name": [
            "D\u00e9partement de M\u00e9decine Interne, Assistance Public des H\u00f4pitaux de Paris, H\u00f4pital Cochin, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guillevin", 
        "givenName": "Lo\u00efc", 
        "id": "sg:person.01264754531.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264754531.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "D\u00e9partement de R\u00e9animation M\u00e9dicale et de M\u00e9decine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lerolle", 
        "givenName": "Nicolas", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Angers", 
          "id": "https://www.grid.ac/institutes/grid.411147.6", 
          "name": [
            "N\u00e9phrologie-Dialyse-Transplantation, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Augusto", 
        "givenName": "Jean-Fran\u00e7ois", 
        "id": "sg:person.01352526461.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352526461.96"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1681/asn.2007010090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003303159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2007010090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003303159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.23800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003700271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2014090903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004274839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2014090903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004274839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0b013e318205a4c6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004735264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0b013e318205a4c6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004735264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcrc.2009.04.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006558023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.37715", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007034872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2010.137778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008449896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0909905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009247104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.14-3098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011657668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.06-2464", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011871919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2169/internalmedicine.52.8863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013763690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.39562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018547912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncprheum0355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020261497", 
          "https://doi.org/10.1038/ncprheum0355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncprheum0355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020261497", 
          "https://doi.org/10.1038/ncprheum0355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/kei217", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022971262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmc1414728", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023462845"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2016.2691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023592567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-016-1189-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024531425", 
          "https://doi.org/10.1186/s13054-016-1189-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-016-1189-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024531425", 
          "https://doi.org/10.1186/s13054-016-1189-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2796.1998.00357.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026448285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2796.1998.00357.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026448285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0909169", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027355308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199711203372106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030293646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/03009740600958611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032273228"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/annrheumdis-2016-209133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032908662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/keg322", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037071879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1993.03510240069035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037698576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0896-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038363295", 
          "https://doi.org/10.1186/s13054-015-0896-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0896-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038363295", 
          "https://doi.org/10.1186/s13054-015-0896-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.34562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041131430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2003.08.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041346293"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lpm.2013.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042071493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc5713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042075619", 
          "https://doi.org/10.1186/cc5713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2009.119032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042502762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2010.216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043094190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/ard.2006.054593", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044437304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2013.06.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044574315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-pathol-011811-132453", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045082419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/08860220802353892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046604035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajic.2016.01.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049351296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1213277", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050446602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201109-1660oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051058583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-143-9-200511010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073708415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079058491", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079093678", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.qjmed.a068882", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082522723"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-12", 
    "datePublishedReg": "2017-12-01", 
    "description": "PURPOSE: Data for ANCA-associated vasculitis (AAV) patients requiring intensive care are scarce.\nMETHODS: We included 97 consecutive patients with acute AAV manifestations (new onset or relapsing disease), admitted to 18 intensive care units (ICUs) over a 10-year period (2002-2012). A group of 95 consecutive AAV patients with new onset or relapsing disease, admitted to two nephrology departments with acute vasculitis manifestations, constituted the control group.\nRESULTS: In the ICU group, patients predominantly showed granulomatosis with polyangiitis and proteinase-3 ANCAs. Compared with the non-ICU group, the ICU group showed comparable Birmingham vasculitis activity score and a higher frequency of heart, central nervous system and lungs involvements. Respiratory assistance, renal replacement therapy and vasopressors were required in 68.0, 56.7 and 26.8% of ICU patients, respectively. All but one patient (99%) received glucocorticoids, 85.6% received cyclophosphamide, and 49.5% had plasma exchanges as remission induction regimens. Fifteen (15.5%) patients died during the ICU stay. The following were significantly associated with ICU mortality in the univariate analysis: the need for respiratory assistance, the use of vasopressors, the occurrence of at least one infection event in ICU, cyclophosphamide treatment, sequential organ failure assessment at admission and simplified acute physiology score II. After adjustment on sequential organ failure assessment or infection, cyclophosphamide was no longer a risk factor for mortality. Despite a higher initial mortality rate of ICU patients within the first hospital stay (p\u00a0<\u00a00.0001), the long-term mortality of hospital survivors did not differ between ICU and non-ICU groups (18.6 and 20.4%, respectively, p\u00a0=\u00a00.36). Moreover, we observed no renal survival difference between groups after a 1-year follow-up (82.1 and 80.5%, p\u00a0=\u00a00.94).\nCONCLUSION: This study supports the idea that experiencing an ICU challenge does not impact the long-term prognosis of AAV patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s13613-017-0262-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045300", 
        "issn": [
          "2110-5820"
        ], 
        "name": "Annals of Intensive Care", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "7"
      }
    ], 
    "name": "Patients with ANCA-associated vasculitis admitted to the intensive care unit with acute vasculitis manifestations: a retrospective and comparative multicentric study", 
    "pagination": "39", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8af4f450cb75dabb7eb406fe4194ef8f9abeb154c855619e37481197571b1af6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28382598"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101562873"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13613-017-0262-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084612633"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13613-017-0262-9", 
      "https://app.dimensions.ai/details/publication/pub.1084612633"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113639_00000004.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs13613-017-0262-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0262-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0262-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0262-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13613-017-0262-9'


 

This table displays all metadata directly associated to this object as RDF triples.

436 TRIPLES      21 PREDICATES      72 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13613-017-0262-9 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N6bfa70e5f44843f4bcd6f02bcfd2935b
4 schema:citation sg:pub.10.1007/bf01709751
5 sg:pub.10.1038/ncprheum0355
6 sg:pub.10.1186/cc5713
7 sg:pub.10.1186/s13054-015-0896-7
8 sg:pub.10.1186/s13054-016-1189-5
9 https://app.dimensions.ai/details/publication/pub.1079058491
10 https://app.dimensions.ai/details/publication/pub.1079093678
11 https://doi.org/10.1001/jama.1993.03510240069035
12 https://doi.org/10.1001/jama.2010.216
13 https://doi.org/10.1001/jama.2016.2691
14 https://doi.org/10.1002/art.23800
15 https://doi.org/10.1002/art.34562
16 https://doi.org/10.1002/art.37715
17 https://doi.org/10.1002/art.39562
18 https://doi.org/10.1016/j.ajic.2016.01.021
19 https://doi.org/10.1016/j.jcrc.2009.04.009
20 https://doi.org/10.1016/j.lpm.2013.08.003
21 https://doi.org/10.1046/j.1365-2796.1998.00357.x
22 https://doi.org/10.1053/j.ajkd.2003.08.015
23 https://doi.org/10.1053/j.ajkd.2013.06.002
24 https://doi.org/10.1056/nejm199711203372106
25 https://doi.org/10.1056/nejmc1414728
26 https://doi.org/10.1056/nejmoa0909169
27 https://doi.org/10.1056/nejmoa0909905
28 https://doi.org/10.1056/nejmoa1213277
29 https://doi.org/10.1080/03009740600958611
30 https://doi.org/10.1080/08860220802353892
31 https://doi.org/10.1093/oxfordjournals.qjmed.a068882
32 https://doi.org/10.1093/rheumatology/keg322
33 https://doi.org/10.1093/rheumatology/kei217
34 https://doi.org/10.1097/md.0b013e318205a4c6
35 https://doi.org/10.1136/annrheumdis-2016-209133
36 https://doi.org/10.1136/ard.2006.054593
37 https://doi.org/10.1136/ard.2009.119032
38 https://doi.org/10.1136/ard.2010.137778
39 https://doi.org/10.1146/annurev-pathol-011811-132453
40 https://doi.org/10.1164/rccm.201109-1660oc
41 https://doi.org/10.1378/chest.06-2464
42 https://doi.org/10.1378/chest.14-3098
43 https://doi.org/10.1681/asn.2007010090
44 https://doi.org/10.1681/asn.2014090903
45 https://doi.org/10.2169/internalmedicine.52.8863
46 https://doi.org/10.7326/0003-4819-143-9-200511010-00005
47 schema:datePublished 2017-12
48 schema:datePublishedReg 2017-12-01
49 schema:description PURPOSE: Data for ANCA-associated vasculitis (AAV) patients requiring intensive care are scarce. METHODS: We included 97 consecutive patients with acute AAV manifestations (new onset or relapsing disease), admitted to 18 intensive care units (ICUs) over a 10-year period (2002-2012). A group of 95 consecutive AAV patients with new onset or relapsing disease, admitted to two nephrology departments with acute vasculitis manifestations, constituted the control group. RESULTS: In the ICU group, patients predominantly showed granulomatosis with polyangiitis and proteinase-3 ANCAs. Compared with the non-ICU group, the ICU group showed comparable Birmingham vasculitis activity score and a higher frequency of heart, central nervous system and lungs involvements. Respiratory assistance, renal replacement therapy and vasopressors were required in 68.0, 56.7 and 26.8% of ICU patients, respectively. All but one patient (99%) received glucocorticoids, 85.6% received cyclophosphamide, and 49.5% had plasma exchanges as remission induction regimens. Fifteen (15.5%) patients died during the ICU stay. The following were significantly associated with ICU mortality in the univariate analysis: the need for respiratory assistance, the use of vasopressors, the occurrence of at least one infection event in ICU, cyclophosphamide treatment, sequential organ failure assessment at admission and simplified acute physiology score II. After adjustment on sequential organ failure assessment or infection, cyclophosphamide was no longer a risk factor for mortality. Despite a higher initial mortality rate of ICU patients within the first hospital stay (p < 0.0001), the long-term mortality of hospital survivors did not differ between ICU and non-ICU groups (18.6 and 20.4%, respectively, p = 0.36). Moreover, we observed no renal survival difference between groups after a 1-year follow-up (82.1 and 80.5%, p = 0.94). CONCLUSION: This study supports the idea that experiencing an ICU challenge does not impact the long-term prognosis of AAV patients.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf Nbf2450f43dba48fa963ef6c85939633f
54 Nc019444550fe47189a26940e91d28133
55 sg:journal.1045300
56 schema:name Patients with ANCA-associated vasculitis admitted to the intensive care unit with acute vasculitis manifestations: a retrospective and comparative multicentric study
57 schema:pagination 39
58 schema:productId N4e04901c68ae4ff7a59787cc16a5cb94
59 N94a00be79260480895877a2d1da32aee
60 N973c54fe262c4e0cbce43e1aecdc70f5
61 Na0100adbd40746a29cfdff7f4d4c99e4
62 Ne844b5ac2730464885f1069d45e9fe05
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084612633
64 https://doi.org/10.1186/s13613-017-0262-9
65 schema:sdDatePublished 2019-04-11T10:27
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N0ae9e903bae54ba1ac816840b420da09
68 schema:url https://link.springer.com/10.1186%2Fs13613-017-0262-9
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N06d500f1a4c64b93aaebb9b8a16952a8 rdf:first sg:person.016427405013.37
73 rdf:rest Nb9f4d8fd409143deb78fade201e584b4
74 N06fef72e59fe4468bf485d839b0a15fb rdf:first sg:person.0736551220.58
75 rdf:rest N735e486acb4e4c9f8b635011a99c2b67
76 N0ae9e903bae54ba1ac816840b420da09 schema:name Springer Nature - SN SciGraph project
77 rdf:type schema:Organization
78 N0cbbfb55d0b8436f8403f66e4421db97 rdf:first sg:person.01332405102.38
79 rdf:rest N695a4ea234e44d7f84670618c9730673
80 N156af8f868ba4aadaba24370b00cbd1d rdf:first sg:person.01126264407.65
81 rdf:rest N455b7f95fd6b43b1b63b3d3584fb5d9e
82 N1d81a0e0be7d40948efa5741656ed8a6 rdf:first sg:person.01076605442.24
83 rdf:rest N0cbbfb55d0b8436f8403f66e4421db97
84 N35086887e1c94214b152784e58d39566 rdf:first N7667596c78014fc3a60ac22651ebab43
85 rdf:rest N9ee84679fbb44b0caea87b1d6be2a6e0
86 N455b7f95fd6b43b1b63b3d3584fb5d9e rdf:first sg:person.0676137344.36
87 rdf:rest N99965dbfacbe49b288730a793106f6c2
88 N4e04901c68ae4ff7a59787cc16a5cb94 schema:name dimensions_id
89 schema:value pub.1084612633
90 rdf:type schema:PropertyValue
91 N4f28f13f28f945cba00c306dd5c8bfd8 rdf:first sg:person.01264754531.19
92 rdf:rest N70680c4b67c84e46aaf90342a50d2788
93 N515b2bfdad70425ba6578ae3764de2f5 schema:name APHP, Hôpital Tenon, Urgences Néphrologiques et Transplantation Rénale, Paris, France
94 rdf:type schema:Organization
95 N57ab1e31f68c420195109440f52434b6 rdf:first sg:person.0730060155.02
96 rdf:rest Nb49af9b224b54151be4b4c4bfe6e27fb
97 N590ad6e48edd487f8d74e03ad8248785 schema:name Medical Intensive Care Unit, Archet 1 University Hospital, Route de St Antoine, CS 23079, 06202, Nice, France
98 rdf:type schema:Organization
99 N5e081da8f21b4fb3bf6a1292b749fdb0 rdf:first sg:person.01237332505.82
100 rdf:rest N06fef72e59fe4468bf485d839b0a15fb
101 N62050bb5eb3749ae973450cb41b20fa1 rdf:first sg:person.0633723234.83
102 rdf:rest N4f28f13f28f945cba00c306dd5c8bfd8
103 N64a72f8ccae8463ebae7937f197341a9 schema:affiliation N590ad6e48edd487f8d74e03ad8248785
104 schema:familyName Dellamonica
105 schema:givenName Jean
106 rdf:type schema:Person
107 N695a4ea234e44d7f84670618c9730673 rdf:first sg:person.01171472721.09
108 rdf:rest N7773dd1ed006410d94571c0d87c78224
109 N6bfa70e5f44843f4bcd6f02bcfd2935b rdf:first sg:person.01044311411.40
110 rdf:rest N06d500f1a4c64b93aaebb9b8a16952a8
111 N70680c4b67c84e46aaf90342a50d2788 rdf:first Naa2a37bf05ef47ed826454db08e340ff
112 rdf:rest Nab88a5d80d3a40fa946f298bb2f511d1
113 N716f702f1e18426fb1f0c30292e9389d schema:name Service de Réanimation Médicale, CHU de Nancy Hôpital Central, 29 Avenue de Lattre de Tassigny, 54035, Nancy Cedex, France
114 rdf:type schema:Organization
115 N735e486acb4e4c9f8b635011a99c2b67 rdf:first sg:person.01350000735.17
116 rdf:rest N1d81a0e0be7d40948efa5741656ed8a6
117 N7667596c78014fc3a60ac22651ebab43 schema:affiliation Nb52c0f306edc436ab43a355eb9a68d11
118 schema:familyName Boyer
119 schema:givenName Sonia
120 rdf:type schema:Person
121 N7773dd1ed006410d94571c0d87c78224 rdf:first sg:person.0724071106.60
122 rdf:rest Nd911ec57dd6e44ceb3497447db8da9a5
123 N8c03ed6d1db44f4eb181d99486e8d5b5 schema:name Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France
124 rdf:type schema:Organization
125 N94a00be79260480895877a2d1da32aee schema:name readcube_id
126 schema:value 8af4f450cb75dabb7eb406fe4194ef8f9abeb154c855619e37481197571b1af6
127 rdf:type schema:PropertyValue
128 N94beb8f9ed4d4770988255558d5c0411 rdf:first sg:person.01101663440.42
129 rdf:rest N62050bb5eb3749ae973450cb41b20fa1
130 N973c54fe262c4e0cbce43e1aecdc70f5 schema:name nlm_unique_id
131 schema:value 101562873
132 rdf:type schema:PropertyValue
133 N997104e722034ec89bc09627262ff854 rdf:first sg:person.01046537257.22
134 rdf:rest N57ab1e31f68c420195109440f52434b6
135 N99965dbfacbe49b288730a793106f6c2 rdf:first N64a72f8ccae8463ebae7937f197341a9
136 rdf:rest N35086887e1c94214b152784e58d39566
137 N9db84a5af8e94dc9b96c01a32d6bb7aa schema:name Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France
138 rdf:type schema:Organization
139 N9ee84679fbb44b0caea87b1d6be2a6e0 rdf:first sg:person.015707336553.56
140 rdf:rest N5e081da8f21b4fb3bf6a1292b749fdb0
141 Na0100adbd40746a29cfdff7f4d4c99e4 schema:name doi
142 schema:value 10.1186/s13613-017-0262-9
143 rdf:type schema:PropertyValue
144 Na46ee8f7875349238983f86738639370 schema:name Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France
145 rdf:type schema:Organization
146 Na936201330b544ad8480c8f90e1d7773 rdf:first sg:person.01057177611.44
147 rdf:rest N156af8f868ba4aadaba24370b00cbd1d
148 Naa2a37bf05ef47ed826454db08e340ff schema:affiliation N8c03ed6d1db44f4eb181d99486e8d5b5
149 schema:familyName Lerolle
150 schema:givenName Nicolas
151 rdf:type schema:Person
152 Nab88a5d80d3a40fa946f298bb2f511d1 rdf:first sg:person.01352526461.96
153 rdf:rest rdf:nil
154 Nb49af9b224b54151be4b4c4bfe6e27fb rdf:first sg:person.01017110566.91
155 rdf:rest Nd3b380242727423d931555b2f9698785
156 Nb52c0f306edc436ab43a355eb9a68d11 schema:name Medical Intensive Care Unit, Archet 1 University Hospital, Route de St Antoine, CS 23079, 06202, Nice, France
157 rdf:type schema:Organization
158 Nb9f4d8fd409143deb78fade201e584b4 rdf:first sg:person.01331205526.47
159 rdf:rest Na936201330b544ad8480c8f90e1d7773
160 Nbf2450f43dba48fa963ef6c85939633f schema:issueNumber 1
161 rdf:type schema:PublicationIssue
162 Nc019444550fe47189a26940e91d28133 schema:volumeNumber 7
163 rdf:type schema:PublicationVolume
164 Nd3b380242727423d931555b2f9698785 rdf:first sg:person.01116303100.51
165 rdf:rest N94beb8f9ed4d4770988255558d5c0411
166 Nd911ec57dd6e44ceb3497447db8da9a5 rdf:first sg:person.01327536175.48
167 rdf:rest N997104e722034ec89bc09627262ff854
168 Ne844b5ac2730464885f1069d45e9fe05 schema:name pubmed_id
169 schema:value 28382598
170 rdf:type schema:PropertyValue
171 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
172 schema:name Medical and Health Sciences
173 rdf:type schema:DefinedTerm
174 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
175 schema:name Clinical Sciences
176 rdf:type schema:DefinedTerm
177 sg:journal.1045300 schema:issn 2110-5820
178 schema:name Annals of Intensive Care
179 rdf:type schema:Periodical
180 sg:person.01017110566.91 schema:affiliation https://www.grid.ac/institutes/grid.411777.3
181 schema:familyName Dequin
182 schema:givenName Pierre-François
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017110566.91
184 rdf:type schema:Person
185 sg:person.01044311411.40 schema:affiliation https://www.grid.ac/institutes/grid.411147.6
186 schema:familyName Demiselle
187 schema:givenName Julien
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044311411.40
189 rdf:type schema:Person
190 sg:person.01046537257.22 schema:affiliation https://www.grid.ac/institutes/grid.11843.3f
191 schema:familyName Boisramé-Helms
192 schema:givenName Julie
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046537257.22
194 rdf:type schema:Person
195 sg:person.01057177611.44 schema:affiliation https://www.grid.ac/institutes/grid.411167.4
196 schema:familyName Gatault
197 schema:givenName Philippe
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057177611.44
199 rdf:type schema:Person
200 sg:person.01076605442.24 schema:affiliation https://www.grid.ac/institutes/grid.418061.a
201 schema:familyName Chudeau
202 schema:givenName Nicolas
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076605442.24
204 rdf:type schema:Person
205 sg:person.01101663440.42 schema:affiliation N716f702f1e18426fb1f0c30292e9389d
206 schema:familyName Bollaert
207 schema:givenName Pierre-Edouard
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101663440.42
209 rdf:type schema:Person
210 sg:person.01116303100.51 schema:affiliation https://www.grid.ac/institutes/grid.411163.0
211 schema:familyName Lautrette
212 schema:givenName Alexandre
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116303100.51
214 rdf:type schema:Person
215 sg:person.01126264407.65 schema:affiliation https://www.grid.ac/institutes/grid.41724.34
216 schema:familyName Grangé
217 schema:givenName Steven
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126264407.65
219 rdf:type schema:Person
220 sg:person.01171472721.09 schema:affiliation https://www.grid.ac/institutes/grid.414293.9
221 schema:familyName Fourrier
222 schema:givenName François
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171472721.09
224 rdf:type schema:Person
225 sg:person.01237332505.82 schema:affiliation https://www.grid.ac/institutes/grid.8515.9
226 schema:familyName Piquilloud
227 schema:givenName Lise
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237332505.82
229 rdf:type schema:Person
230 sg:person.01264754531.19 schema:affiliation https://www.grid.ac/institutes/grid.411784.f
231 schema:familyName Guillevin
232 schema:givenName Loïc
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264754531.19
234 rdf:type schema:Person
235 sg:person.01327536175.48 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
236 schema:familyName Guérot
237 schema:givenName Emmanuel
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327536175.48
239 rdf:type schema:Person
240 sg:person.01331205526.47 schema:affiliation Na46ee8f7875349238983f86738639370
241 schema:familyName Beloncle
242 schema:givenName François
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331205526.47
244 rdf:type schema:Person
245 sg:person.01332405102.38 schema:affiliation https://www.grid.ac/institutes/grid.411784.f
246 schema:familyName Geri
247 schema:givenName Guillaume
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332405102.38
249 rdf:type schema:Person
250 sg:person.01350000735.17 schema:affiliation https://www.grid.ac/institutes/grid.457374.6
251 schema:familyName Guitton
252 schema:givenName Christophe
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350000735.17
254 rdf:type schema:Person
255 sg:person.01352526461.96 schema:affiliation https://www.grid.ac/institutes/grid.411147.6
256 schema:familyName Augusto
257 schema:givenName Jean-François
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352526461.96
259 rdf:type schema:Person
260 sg:person.015707336553.56 schema:affiliation https://www.grid.ac/institutes/grid.134996.0
261 schema:familyName Beauport
262 schema:givenName Dimitri Titeca
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015707336553.56
264 rdf:type schema:Person
265 sg:person.016427405013.37 schema:affiliation N9db84a5af8e94dc9b96c01a32d6bb7aa
266 schema:familyName Auchabie
267 schema:givenName Johann
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016427405013.37
269 rdf:type schema:Person
270 sg:person.0633723234.83 schema:affiliation https://www.grid.ac/institutes/grid.11843.3f
271 schema:familyName Meziani
272 schema:givenName Ferhat
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633723234.83
274 rdf:type schema:Person
275 sg:person.0676137344.36 schema:affiliation https://www.grid.ac/institutes/grid.411149.8
276 schema:familyName Du Cheyron
277 schema:givenName Damien
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676137344.36
279 rdf:type schema:Person
280 sg:person.0724071106.60 schema:affiliation https://www.grid.ac/institutes/grid.411162.1
281 schema:familyName Robert
282 schema:givenName René
283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724071106.60
284 rdf:type schema:Person
285 sg:person.0730060155.02 schema:affiliation N515b2bfdad70425ba6578ae3764de2f5
286 schema:familyName Galichon
287 schema:givenName Pierre
288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730060155.02
289 rdf:type schema:Person
290 sg:person.0736551220.58 schema:affiliation https://www.grid.ac/institutes/grid.414271.5
291 schema:familyName Letheulle
292 schema:givenName Julien
293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736551220.58
294 rdf:type schema:Person
295 sg:pub.10.1007/bf01709751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052044737
296 https://doi.org/10.1007/bf01709751
297 rdf:type schema:CreativeWork
298 sg:pub.10.1038/ncprheum0355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020261497
299 https://doi.org/10.1038/ncprheum0355
300 rdf:type schema:CreativeWork
301 sg:pub.10.1186/cc5713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042075619
302 https://doi.org/10.1186/cc5713
303 rdf:type schema:CreativeWork
304 sg:pub.10.1186/s13054-015-0896-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038363295
305 https://doi.org/10.1186/s13054-015-0896-7
306 rdf:type schema:CreativeWork
307 sg:pub.10.1186/s13054-016-1189-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024531425
308 https://doi.org/10.1186/s13054-016-1189-5
309 rdf:type schema:CreativeWork
310 https://app.dimensions.ai/details/publication/pub.1079058491 schema:CreativeWork
311 https://app.dimensions.ai/details/publication/pub.1079093678 schema:CreativeWork
312 https://doi.org/10.1001/jama.1993.03510240069035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037698576
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1001/jama.2010.216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043094190
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1001/jama.2016.2691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023592567
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1002/art.23800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003700271
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1002/art.34562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041131430
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1002/art.37715 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007034872
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1002/art.39562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018547912
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/j.ajic.2016.01.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049351296
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/j.jcrc.2009.04.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006558023
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/j.lpm.2013.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042071493
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1046/j.1365-2796.1998.00357.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026448285
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1053/j.ajkd.2003.08.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041346293
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1053/j.ajkd.2013.06.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044574315
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1056/nejm199711203372106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030293646
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1056/nejmc1414728 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023462845
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1056/nejmoa0909169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027355308
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1056/nejmoa0909905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009247104
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1056/nejmoa1213277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050446602
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1080/03009740600958611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032273228
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1080/08860220802353892 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046604035
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1093/oxfordjournals.qjmed.a068882 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082522723
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1093/rheumatology/keg322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037071879
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1093/rheumatology/kei217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022971262
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1097/md.0b013e318205a4c6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004735264
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1136/annrheumdis-2016-209133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032908662
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1136/ard.2006.054593 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044437304
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1136/ard.2009.119032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042502762
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1136/ard.2010.137778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008449896
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1146/annurev-pathol-011811-132453 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045082419
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1164/rccm.201109-1660oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1051058583
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1378/chest.06-2464 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011871919
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1378/chest.14-3098 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011657668
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1681/asn.2007010090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003303159
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1681/asn.2014090903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004274839
379 rdf:type schema:CreativeWork
380 https://doi.org/10.2169/internalmedicine.52.8863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013763690
381 rdf:type schema:CreativeWork
382 https://doi.org/10.7326/0003-4819-143-9-200511010-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073708415
383 rdf:type schema:CreativeWork
384 https://www.grid.ac/institutes/grid.11843.3f schema:alternateName University of Strasbourg
385 schema:name EA 7293, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Université de Strasbourg, Strasbourg, France
386 Service de Réanimation Médicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
387 rdf:type schema:Organization
388 https://www.grid.ac/institutes/grid.134996.0 schema:alternateName Centre Hospitalier Universitaire D' Amiens
389 schema:name Medical Intensive Care Unit, Amiens University Medical Center, 80054, Amiens, Cedex 1, France
390 rdf:type schema:Organization
391 https://www.grid.ac/institutes/grid.411147.6 schema:alternateName Centre Hospitalier Universitaire de Angers
392 schema:name Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France
393 Néphrologie-Dialyse-Transplantation, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France
394 rdf:type schema:Organization
395 https://www.grid.ac/institutes/grid.411149.8 schema:alternateName Centre Hospitalier Universitaire de Caen
396 schema:name Service de Réanimation Médicale, CHU de Caen, Avenue de la Côte de Nacre, CS 30001, 14033, Caen Cedex 9, France
397 rdf:type schema:Organization
398 https://www.grid.ac/institutes/grid.411162.1 schema:alternateName Centre Hospitalier Universitaire de Poitiers
399 schema:name Service de Réanimation Médicale, CHU de Poitiers, Poitiers, France
400 rdf:type schema:Organization
401 https://www.grid.ac/institutes/grid.411163.0 schema:alternateName Centre Hospitalier Universitaire de Clermont-Ferrand
402 schema:name Service de Réanimation Médicale Polyvalente, CHU Gabriel Montpied, 58 rue Montalembert, 63000, Clermont-Ferrand, France
403 rdf:type schema:Organization
404 https://www.grid.ac/institutes/grid.411167.4 schema:alternateName Centre Hospitalier Universitaire de Tours
405 schema:name Service de Néphrologie et Immunologie Clinique, CHRU Tours, Tours, France
406 rdf:type schema:Organization
407 https://www.grid.ac/institutes/grid.411777.3 schema:alternateName Bretonneau Hospital
408 schema:name Service de Réanimation Polyvalente, Hôpital Bretonneau, Tours, France
409 rdf:type schema:Organization
410 https://www.grid.ac/institutes/grid.411784.f schema:alternateName Hôpital Cochin
411 schema:name Département de Médecine Interne, Assistance Public des Hôpitaux de Paris, Hôpital Cochin, Paris, France
412 Service de Réanimation Médicale, Hôpital Cochin, Paris, France
413 rdf:type schema:Organization
414 https://www.grid.ac/institutes/grid.414093.b schema:alternateName Hôpital Européen Georges-Pompidou
415 schema:name Service de Réanimation Médicale, Hôpital Européen Georges Pompidou, Paris, France
416 rdf:type schema:Organization
417 https://www.grid.ac/institutes/grid.414271.5 schema:alternateName l'Hôpital Pontchaillou
418 schema:name Service de Réanimation Médicale, Hôpital Pontchaillou, CHU Rennes, 2 rue Henri Le Guilloux, 35033, Rennes Cedex, France
419 rdf:type schema:Organization
420 https://www.grid.ac/institutes/grid.414293.9 schema:alternateName Hôpital Roger Salengro
421 schema:name Réanimation, Centre de Réanimation Polyvalente, Hôpital Roger Salengro, CHRU de Lille, Lille, France
422 rdf:type schema:Organization
423 https://www.grid.ac/institutes/grid.41724.34 schema:alternateName Centre Hospitalier Universitaire De Rouen
424 schema:name Medical Intensive Care Unit, Rouen University Hospital, Rouen, France
425 rdf:type schema:Organization
426 https://www.grid.ac/institutes/grid.418061.a schema:alternateName Centre Hospitalier du Mans
427 schema:name Service de Reanimation Medico-Chirurgicale, Centre Hospitalier du Mans, 194 Avenue Rubillard, 72037, Le Mans, France
428 rdf:type schema:Organization
429 https://www.grid.ac/institutes/grid.457374.6 schema:alternateName Délégation Grand-Ouest
430 schema:name Medical Intensive Care Unit, Hôtel-Dieu, University Hospital of Nantes, 30 bd Jean Monnet, 44093, Nantes, France
431 UMR 1064, Inserm, 30 bd Jean Monnet, 44093, Nantes, France
432 rdf:type schema:Organization
433 https://www.grid.ac/institutes/grid.8515.9 schema:alternateName University Hospital of Lausanne
434 schema:name Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, 4 rue Larrey, 49933, Angers Cedex 9, France
435 Service de Médecine Intensive Adulte et Centre des Brûlés, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
436 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...