7th Drug hypersensitivity meeting: part two View Full Text


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DATE

2016-08-25

AUTHORS

Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez, Jaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De Rojas, Emre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan, Peyker Temiz, Chien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung Chung, Fabrícia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. Cernadas, Luis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, José Francisco Da Silva Franco, Leandra Queiroz, Dirceu Solé, Ceyda Tunakan Dalgiç, Aytül Zerrin Sin, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Ali Kokuludag, Ana M. Montoro De Francisco, Talía Mª De Vicente Jiménez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia García Luque, Luis Amaral, Leonor Carneiro Leão, Nicole Pinto, Joana Belo, João Marques, Pedro Carreiro-Martins, Paula Leiria-Pinto, Amel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim Aouam, Astrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito Sabato, Anabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Lourenço, Maria-João Paes, Amélia Spínola-Santos, Manuel Pereira-Barbosa, Cíntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe Inácio, Filipe Benito-Garcia, Inês Mota, Magna Correia, Ângela Gaspar, Marta Chambel, Susana Piedade, Mário Morais-Almeida, Alla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr Lapshyn, Pablo Andrés Miranda, Bautista De La Cruz Hoyos, Aranzazu Jimenez Blanco, Marta Del Pozo, Alessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico Maggi, Ivana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta Simic, Yukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko Aihara, Jaechun Jason Lee, Jay Chol Choi, Hwa Young Lee, Rosa-Anita Rodrigues Fernandes, Emília Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo Bom, Ana Rodolfo, Eunice Dias-Castro, Marina Voronova, Diana Kury Valle, Verónica Pacheco Coronel, Carolina Perales Chordá, Roselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D’Amelio, Amalia Bernad, Olga Vega, Gabriel Gastaminza, Beatriz Pola Bibián, Marina Lluncor Salazar, Gemma Vilà-Nadal, Ana María Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Muñoz, Santiago Quirce Gancedo, Maria Rosario Cabañas Moreno, Kathrin Scherer Hofmeier, Vladyslava Barzylovych, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bellón, Javier Domínguez, Santiago Quirce, Min-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang, Clémence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick Barbaud, Najah Ben Fadhel, Sandra Jerkovic Gulin, Anca Chiriac, Bárbara Kong Cardoso, Regina Viseu, Ana Moreira, Susana Cadinha, Ana Castro Neves, Patrícia Barreira, Daniela Malheiro, J. P. Moreira Da Silva, Ružica Jurakic-Toncic, Suzana Ljubojevic, Petra Turcic, Liesbeth Gilissen, Sara Huygens, An Goossens, Inmaculada Andreu, Alicia Martinez Romero, Pau Gomez Cabezas, Pedro Ayuso Parejo, Maria Del Carmen Plaza-Serón, Inmaculada Doña, Natalia Blanca-López, Carlos Flores, María Luisa Galindo, Ana Molina, James Richard Perkins, José Antonio Cornejo-García, José Augusto García-Agúndez, Elena García-Martín, Paloma Campo, María Gabriela Canto, Miguel Blanca, Rosa María Guéant-Rodríguez, Raquel Jurado-Escobar, Esther Barrionuevo, María Salas, Gabriela Canto, Jean-Louis Guéant, Toru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. Naisbitt, Oswaldo Trelles, María Auxiliadora Guerrero, Alex Upton, Mayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru Kinoshita, Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong Klaewsongkram, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. Theeramoke, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Castañer, Francisco José De Abajo, Violeta Régnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana Castells, Elisa Boni, Marina Russello, Marina Mauro, Kok Loong Ue, Krzysztof Rutkowski, Victor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cantó Reig, Javier Fernandez Sanchez, Christine Breynaert, Erna Van Hoeyveld, Rik Schrijvers, Aranzazu Jimenez Blanco, Raquel Fuentes Irigoyen, Daniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, María José Torres, Line K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-Jensen, Wolfgang Pfützner, Hannah Dörnbach, Johanna Visse, Michele Rauber, Christian Möbs, Abdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. Rieder, Jason Trubiano, Emily Woolnough, Kaija Stautins, Christina Cheng, Kenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro Katayama, Toshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki Tokura, Mira Silar, Mihaela Zidarn, Helena Rupnik, Peter Korosec, Alec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Simon Mallal, Rosario Cabañas, Ana María Fiandor, Andrew Sullivan, Paul Whitaker, Daniel Peckham, Wei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-Jones, Yumi Aoyama, Tetsuo Shiohara, Sara Correia, Asli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin Çatin-Aktas, Gunnur Deniz, Jose Julio Laguna, J. Dionicio, Tahia Fernandez, I. Olazabal, Maria Dolores Ruiz, Maria José Torres, Alberto Lafuente, Jorge Núñez, Tahia Diana Fernández, Francisca Palomares, Rubén Fernández, Maria Isabel Sanchez, Tahía Fernandez, Arturo Ruiz, Adriana Ariza, Amalia Bernad Alonso, Carmen D’Amelio Garófalo, Olga Vega Matute, Marta Ferrer Puga, María José Goikoetxea Lapresa, Gabriel Gastaminza Lasarte, Antonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina Balakirski, Andrew Gibson, Monday Ogese, Zaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, John Farrel, Khetam Alhilali, Yanni Xue, Patricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony Purcell, Monday O. Ogese, Catherine Betts, Paul Thomson, Mohammad Alhaidari, Neill Berry, Paul M. O’Neill, Abdulaziz Alzahrani, Marie Eliane Azoury, Lucia Fili, Rami Bechara, Noémie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc Pallardy, Axel Patrice Villani, Aurore Rozières, Benoît Bensaïd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Janet Maryanski, Jean-François Nicolas, Osami Kanagawa, Marc Vocanson, Shuen-Iu Hung, Caroline J. Harrison, Rosalind E. Jenkins, Neil S. French, Maria Isabel Montañez, Tahia D. Fernandez, Angela Martin-Serrano, Maria Jose Torres, Noemi Molina, Sally Wood, Munir Pirmohamed, María Isabel Montañez, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Antonio E. Guzmán, Tai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn Wu, Francisco J. Sánchez-Gómez, Juan M. González-Morena, María J. Torres, Alejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Noe Valentin Duran Figueroa, Jose Luis Castrejon Flores, James Perkins, Diana Pérez-Alzate, Gador Bogas, María J Torres, Luis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiago

ABSTRACT

Table of contentsPoster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101)P92 16 years of experience with proton pump inhibitors (PPIs)Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna MartinezP93 Allergy evaluation of quinolone induced adverse reactionsJaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De RojasP94 Bupropion-induced acute urticaria and angioedema, a case reportEmre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan, Peyker TemizP96 Delayed type hypersensitivity and study of cross-reactivity between proton-pump inhibitorsChien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung ChungP97 Diagnostic work-up in suspected hypersensitivity to proton-pump inhibitors: looking at cross-reactivityFabrícia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. CernadasP98 Management of infusion-related hypersensitivity reactions to enzyme replacement therapy for lysosomal diseasesLuis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, José Francisco Da Silva Franco, Leandra Queiroz, Dirceu SoléP99 Management of insulin allergy with continuous subcutaneous insulin infusionCeyda Tunakan Dalgiç, Aytül Zerrin Sin, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Ali KokuludagP100 Off-label use of icatibant for management of serious angioedema associated with angiotensin inhibitorsAna M. Montoro De Francisco, Talía Mª De Vicente Jiménez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia García LuqueP101 Thiocolchicoside anaphylaxis: an unusual suspect?Luis Amaral, Fabricia Carolino, Leonor Carneiro Leão, Eunice Castro, Josefina CernadasPoster walk 12: betalactam hypersensitivity (P102–P111)P102 A curious delayed reading: a case report of a β-lactam allergy in a childNicole Pinto, Joana Belo, João Marques, Pedro Carreiro-Martins, Paula Leiria-PintoP103 Betalactam-induced hypersensitivity: a 10-years’ experienceAmel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim AouamP104 Cefazolin hypersensitivity: towards optimized diagnosisAstrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito SabatoP105 Clavulanic acid allergy: two cases reportAnabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Lourenço, Maria-João Paes, Amélia Spínola-Santos, Manuel Pereira-BarbosaP106 Diagnosis of betalactam allergy in an allergy departmentCíntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe InácioP107 Diagnostic work-up of 410 patients with suspicion of betalactam antibiotic hypersensitivityFilipe Benito-Garcia, Inês Mota, Magna Correia, Ângela Gaspar, Marta Chambel, Susana Piedade, Mário Morais-AlmeidaP108 Immediate selective hypersensitivity reactions to clavulanic acidAlla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr LapshynP109 Prevalence and incidence of penicillin hypersensitivity reactions in ColombiaPablo Andrés Miranda, Bautista De La Cruz HoyosP110 Selective sensitization to amoxicilin and clavulanic acidJose Julio Laguna Martinez, Aranzazu Jimenez Blanco, Javier Dionicio Elera, Cosmin Boteanu, Rosario Gonzalez-Mendiola, Marta Del PozoP111 Infliximab-specific T cells are detectable also in treated patients who have not developed anti-drug antibodiesAlessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico MaggiPoster walk 13: biologicals, local anesthetics, others (P112–P118)P112 A case report of allergic immediate systemic reaction to adalimumab and certolizumabCeyda Tunakan Dalgiç, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Aytül Zerrin Sin, Ali KokuludagP113 Allergy to local anesthetics: negative predictive value of skin testsIvana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta SimicP114 Cutaneous adverse reactions of molecular targeted agents: a retrospective analysis in 150 patients in our departmentYukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko AiharaP115 Generalized paralysis induced by local lidocaine injectionJaechun Jason Lee, Jay Chol Choi, Hwa Young LeeP116 Hypersensitivity to local anaesthetics: a 10 year reviewRosa-Anita Rodrigues Fernandes, Emília Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo BomP117 Local anaesthetics: a rare culprit in hypersensitivity reactionsAna Rodolfo, Eunice Dias-Castro, Josefina CernadasP118 Stevens–Johnson syndrome in clinical practice: a variant of clinical courseMarina VoronovaPoster walk 14: RCM (P119–P128)P119 13 cases of severe anaphylactic reactions due to radiocontrast mediaJaume Martí Garrido, Ramon Lopez Salgueiro, Diana Kury Valle, Verónica Pacheco Coronel, Carolina Perales Chordá, Dolores Hernandez Fernandez De RojasP120 Anaphylactic shock after administration of iodinated contrast medium during cardiac catheterizationRoselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D’Amelio, Amalia Bernad, Olga Vega, Gabriel GastaminzaP121 Anaphylactic shock and cardiac arrest induced by gadolinium-based contrast agentsBeatriz Pola Bibián, Marina Lluncor Salazar, Gemma Vilà Nadal, Ana María Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Muñoz, Santiago Quirce Gancedo, Maria Rosario Cabañas MorenoP122 Anaphylaxis to gadobenate and cross-reactivity to other gadolinium-based contrast agents in two patientsKathrin Scherer HofmeierP123 Anaphylaxis to glatiramer acetate in a patient with multiple sclerosisFabrícia Carolino, Vladyslava Barzylovych, Josefina R. CernadasP124 Delayed hypersensitivity reaction to radiocontrast mediaFabrícia Carolino, Diana Silva, Leonor Leão, Josefina R. CernadasP125 Drug reaction with eosinophilia and systemic symptoms induced by iodixanolGemma Vilà-Nadal, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bellón, Javier Domínguez, Santiago QuirceP126 Electronic consultation support system for radiocontrast media hypersensitivity changes clinician’s behaviorMin-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok ChangP127 Hypersensitivity reactions to iodinated contrast media: skin testing and follow-upDanica Juricic Nahal, Ivana Cegec, Viktorija Erdeljic Turk, Iva Kraljickovic, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iveta SimicP128 Would iodine allergy exist?Clémence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick BarbaudPoster walk 15: MPE/type 4 (P129–P137)P129 Delayed hypersensitivity cutaneous reactions: a case/control study from a tunisian databaseKarim Aouam, Najah Ben Fadhel, Zohra Chadly, Nadia Ben Fredj, Naceur A. Boughattas, Amel ChaabaneP130 Delayed hypersensitivity reactions to cephalosporins: a review of seven casesJoana Cosme, Anabela Lopes, Amélia Spínola-Santos, Manuel Pereira-BarbosaP131 Diclofenac induced allergic contact dermatitis: case series of four patientsSandra Jerkovic Gulin, Anca ChiriacP132 Late-onset maculopapular rash to irbesartanBárbara Kong Cardoso, Elza Tomaz, Regina Viseu, Filipe InácioP133 Nonimmediate hypersensitivity reactions to betalactams: a retrospective analysisAna Moreira, Susana Cadinha, Ana Castro Neves, Patricia Barreira, Daniela Malheiro, J. P. Moreira Da SilvaP134 Occupational airborne contact dermatitis to omeprazoleRužica Jurakic-Toncic, Suzana Ljubojevic, Petra TurcicP135 Ornidazole-induced fixed drug eruption confirmed by positive patch test on a residual pigmented lesionLiesbeth Gilissen, Sara Huygens, An GoossensP136 Repeated delayed reaction induced by amoxicillin and amoxicillin clavulanateInmaculada Andreu, Ramon Lopez-Salgueiro, Alicia Martinez Romero, Pau Gomez CabezasP137 Systemic photosensitivity from fenofibrate in a patient photo-sensitized to ketoprofenLiesbeth Gilissen, An GoossensPoster walk 16: HLA genetics (P138–P146)P138 A copy number variation in ALOX5 and PTGER1 is associated with nonsteroidal anti-inflammatory drugs induced urticaria and/or angioedemaPedro Ayuso Parejo, Maria Del Carmen Plaza-Serón, Inmaculada Doña, Natalia Blanca López, Carlos Flores, Luisa Galindo, Ana Molina, James Richard Perkins, Jose Antonio Cornejo-García, José Augusto García-Agúndez, Elena García-Martín, Paloma Campo, María Gabriela Canto, Miguel BlancaP139 Association of galectin-3 (LGALS3) single nucleotide polymorphisms with non-steroidal anti-inflammatory drugs-induced urticaria/angioedemaJosé Antonio Cornejo-Garcia, Inmaculada Doña, Rosa María Guéant-Rodríguez, Natalia Blanca-López, María Carmen Plaza-Serón, Raquel Jurado-Escobar, Esther Barrionuevo, María Salas, María Luisa Galindo, Gabriela Canto, Miguel Blanca, Jean-Louis GuéantP140 Detection of T cell responses to ticlopidine using peripheral blood mononuclear cells from HLA-A*33:03+ healthy donorsToru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. NaisbittP141 Epistasis approaches to identify novel genes potentially involved in NSAIDs hypersensitivityJames Richard Perkins, Jose Antonio Cornejo García, Oswaldo Trelles, Inmaculada Doña, Esther Barrionuevo, María Salas, María Auxiliadora Guerrero, Miguel Blanca, Alex UptonP142 Genetic predisposition of cold medicine related SJS/TEN with severe ocular complicationsMayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru KinoshitaP143 HLA-B*13:01 and dapsone induced hypersensitivity in Thai populationChonlaphat Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong KlaewsongkramP144 HLA-B*15:02 alleles and lamotrigine-induced cutaneous adverse drug reactions in ThaiChonlaphat Sukasem, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. TheeramokeP145 HLA-B*38:01 and HLA-A*24:02 allele frequencies in Spanish patients with lamotrigine-induced SCARsTeresa Bellón, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Castañer, Francisco José De AbajoP146 Overrepresentation of a class II HLA haplotype in severe hypersensitivity type I reactions to carboplatinVioleta Régnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana CastellsPoster walk 17: in vivo diagnosis + sIgE (P147–P154)P147 Absence of specific Ig-e against beta-lactams 9 months after an allergic reaction to amoxicillin-clavulanic acidElisa Boni, Marina Russello, Marina MauroP148 Drug provocation tests in suspected opioid allergyKok Loong Ue, Krzysztof RutkowskiP149 Improvement to the specific IgE cut-off in the assess of β-lactamic allergyVictor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cantó Reig, Javier Fernandez SanchezP150 Initial false negative specific IgE to gelatin in a patient with gelatin-induced anaphylaxisChristine Breynaert, Erna Van Hoeyveld, Rik SchrijversP151 Inmediate reactions to beta-lactam antibiotics: pattern of skin test response over the timeJose Julio Laguna Martinez, Rosario Gonzalez Mendiola, Javier Dionicio Elera, Cosmin Boteanu, Aranzazu Jimenez Blanco, Marta Del Pozo, Raquel Fuentes IrigoyenP152 New fluorescent dendrimeric antigens for the evaluation of dendritic cell maturation as a test to detect allergy reactions to amoxicillinDaniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, María José Torres, Miguel BlancaP153 Positive skin test or positive specific IgE to penicillin does not predict penicillin allergyLine K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-JensenP154 Significance of skin testing and in vitro-analysis of neuromuscular blocking agents in diagnosis of perioperative drug hypersensitivity: evaluation of a negative control populationWolfgang Pfützner, Hannah Dörnbach, Johanna Visse, Michele Rauber, Christian MöbsPoster walk 18: in vitro/ex vivo (P155–P158, P160–P164)P155 Diagnostic value of the lymphocyte toxicity assay (LTA) and the in vitro platelet toxicity assay (IPTA) for β-lactam allergyAbdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. RiederP156 Enzyme linked immunospot assay used in the diagnosis of severe cutaneous adverse reactions to antimicrobialsAlec Redwood, Jason Trubiano, Rebecca Pavlos, Emily Woolnough, Kaija Stautins, Christina Cheng, Elizabeth PhillipsP157 Evaluation of in vitro diagnostic methods for identifying the culprit drugs in drug hypersensitivityKenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro KatayamaP158 Ex-vivo expanded skin-infiltrating T cells from severe drug eruptions are reactive with causative drugs: a possible novel method for determination of causative drugsToshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki TokuraP160 In vitro release of IL-2, IL-5 and IL-13 in diagnosis of patients with delayed-type nickel hypersensitivityMira Silar, Mihaela Zidarn, Helena Rupnik, Peter KorosecP161 Single cell analysis of drug responsive T cells; identification of candidate drug reactive T cell receptors in abacavir and carbamazepine hypersensitivityAlec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Rebecca Pavlos, Simon Mallal, Elizabeth PhillipsP162 Specificity and sensitivity of LTT in DRESS: analysis of agreement with the Spanish pharmacovigilance system probability algorithmRosario Cabañas, Elena Ramirez, Ana María Fiandor, Teresa BellónP163 The role of interleukin-22 in β-lactam hypersensitivityAndrew Sullivan, Paul Whitaker, Daniel Peckham, B. Kevin Park, Dean J. NaisbittP164 Vancomycin-specific T cell responses and teicoplanin cross-reactivityWei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-JonesPoster walk 19: BAT and biomarkers (P165–P173)P165 A combination of early biomarkers useful for the prediction of severe ADRsYumi Aoyama, Tetsuo ShioharaP166 Basophil activation test in the diagnostic approach of reactions during general anaesthesiaAna Moreira, Susana Cadinha, Patrícia Barreira, Ana Castro Neves, Daniela Malheiro, Sara Correia, J. P. Moreira Da SilvaP167 IL-10 can be related to successful desensitizationAsli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin Çatin-Aktas, Gunnur DenizP168 Immediate reactions to proton pump inhibitors: value of basophil activation testMaria Salas, Jose Julio Laguna, Esther Barrionuevo, J. Dionicio, Tahia Fernandez, R. Gonzalez-Mendiola, I. Olazabal, Maria Dolores Ruiz, Miguel Blanca, Cristobalina Mayorga, Maria José TorresP169 Improvement of the elevated tryptase criterion to discriminate IgE from non-IgE mediated allergic reactionsGabriel Gastaminza, Alberto Lafuente, Carmen D’Amelio, Amalia Bernad, Olga Vega, Roselle Catherine Madamba, M. Jose Goikoetxea, Marta Ferrer, Jorge NúñezP170 Low expression of Tim-3 could serve as a biomarker for control and diagnose maculopapular exanthema induced by drugsTahia Diana Fernández, Inmaculada Doña, Francisca Palomares, Rubén Fernández, Maria Salas, Esther Barrionuevo, Maria Isabel Sanchez, Miguel Blanca, Maria José Torres, Cristobalina MayorgaP171 Role of basophil activation test using two different activation markers for the diagnosis of allergy to fluoroquinolonesEsther Barrionuevo, Tahía Fernandez, Arturo Ruiz, Adriana Ariza, Maria Salas, Inmaculada Doña, Ana Molina, Miguel Blanca, Maria Jose Torres, Cristobalina MayorgaP172 The importance of basophil activation test in anaphylaxis due to celecoxibAmalia Bernad Alonso, Carmen D’Amelio Garófalo, Olga Vega Matute, Marta Ferrer Puga, María José Goikoetxea Lapresa, Roselle Catherine Yu Madamba, Gabriel Gastaminza LasarteP173 The role of basophil activation test in the diagnosis of immediate type drug hypersensitivity to betalactam antibioticsAntonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina BalakirskiPoster walk 20: TCR recognition, cellular (P174–P183)P174 Characterisation of the effect of co-inhibitory signalling on the activation of drug-derived antigen-specific T-cellsAndrew Gibson, Monday Ogese, Lee Faulkner, B. Kevin Park, Dean J. NaisbittP175 Characterization of drug hapten-specific T cell responses in piperacillin hypersensitive patientsZaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, Paul Whitaker, Daniel Peckham, Lee Faulkner, John Farrel, Kevin Park, Dean NaisbittP176 Characterization of the response of T-cells to telaprevir and its metabolite in normal volunteersZaid Al-Attar, Khetam Alhilali, Yanni Xue, John Farrell, Lee Faulkner, Kevin Park, Dean NaisbittP177 Characterization of the T cell receptor signatures of drug-responsive T cellsPatricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony PurcellP178 Defining the signals between hepatocytes and immune cells in idiosyncratic drug-induced liver injury (DILI)Monday O. Ogese, Lee Faulkner, B. Kevin Park, Catherine Betts, Dean J. NaisbittP179 Development of novel chemicals that do not bind to HLA-B*57:01 or activate CD8 + T-cells through modification of the 6-amino cyclopropyl group of abacavirPaul Thomson, John Farrell, Mohammad Alhaidari, Neill Berry, Paul M. O’Neill, B. Kevin Park, Dean J. NaisbittP180 Generation and characterization of dapsone- and nitroso-dapsone-specific T-cell clones using lymphocytes from healthy volunteersAbdulaziz Alzahrani, Monday O. Ogese, John Farrell, Lee Faulkner, Andrew Gibson, Arun Tailor, B. Kevin Park, Dean J. NaisbittP181 Identification of benzylpenicillin-hapten peptides responsible for naïve T-cell activation and immunization of allergic patients to penicillinMarie Eliane Azoury, Lucia Fili, Rami Bechara, Noémie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc PallardyP182 Massive expansion of clonotypic and polycytotoxic CD8+ T cells in toxic epidermal necrolysisAxel Patrice Villani, Aurore Rozières, Benoît Bensaïd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Marc Pallardy, Janet Maryanski, Jean-François Nicolas, Osami Kanagawa, Marc VocansonP183 Pharmaco-immunological synapse of HLA-drug-TCR in SCARShuen-Iu HungPoster walk 21: new in vitro methods, haptens, etc. (P184–P194)P184 Amoxicillin-clavulanate forms distinct multiple haptenic structures on human serum albumin in patientsXiaoli Meng, Arun Tailor, Caroline J. Harrison, Rosalind E. Jenkins, Paul Whitaker, Neil S. French, Dean J. Naisbitt, B. Kevin ParkP185 Dendrimeric antigens for studying the influence of penicillin determinants orientation on IgE recognitionMaria Isabel Montañez, Cristobalina Mayorga, Francisco Najera, Adriana Ariza, Tahia D. Fernandez, Maria Salas, Angela Martin-Serrano, Miguel Blanca, Ezequiel Perez-Inestrosa, Maria Jose TorresP186 Dendrimeric antigens on solid supports: designed materials for IgE quantificationYolanda Vida, Maria Isabel Montañez, Noemi Molina, Daniel Collado, Francisco Najera, Adriana Ariza, Maria Jose Torres, Cristobalina Mayorga, Ezequiel Perez-InestrosaP187 Development of a screening assay for drug hypersensitivity using naïve T cells from donors with seven different HLA class I risk allelesLee Faulkner, Sally Wood, Ana Alfirevic, Munir Pirmohamed, Dean J. Naisbitt, B. Kevin ParkP188 Different patterns of recognition of structures derived from amoxicillin by IgE antibodies from patients with immediate hypersensitivity reactions to betalactamsAdriana Ariza, Cristobalina Mayorga, María Isabel Montañez, María Salas, Inmaculada Doña, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Miguel Blanca, Antonio E. Guzmán, María José TorresP189 High-resolution typing of HLA polymorphism and T-cell receptor repertoire for severe adverse drug reactions based on the cost-effective next-generation sequencing approachesTai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn WuP190 Identification and fate of intracellular proteins haptenated by amoxicillinFrancisco J. Sánchez-Gómez, Juan M. González-Morena, Yolanda Vida, Ezequiel Pérez-Inestrosa, Miguel Blanca, María J. Torres, Dolores Pérez-SalaP191 In vitro detection of terbinafine protein adductsArun Tailor, Toru Usui, Yanni Xue, Xiaoli Meng, Dean J. Naisbitt, B. Kevin ParkP192 MicroRNAs dysregulation in PBMCs from drug hypersensitivity patients during drug challenge in vitroAlejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Dean J. Naisbitt, Noe Valentin Duran Figueroa, Jose Luis Castrejon FloresP193 NSAIDs-exacerbated cutaneous disease: high throughput gene expression profilingJosé Antonio Cornejo-García, James Perkins, Natalia Blanca-López, Diana Pérez-Alzate, Raquel Jurado-Escobar, Inmaculada Doña, Gador Bogas, María J. Torres, Gabriela Canto, Miguel BlancaP194 Utility of skin tests in non-immediate reactions to amoxicillinLuis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiago More... »

PAGES

30

Journal

TITLE

Clinical and Translational Allergy

ISSUE

Suppl 3

VOLUME

6

Author Affiliations

  • Allergy Unit, Hospital Central de la Cruz Roja, Madrid, Spain
  • Hospital de la Cruz Roja, Madrid, Spain
  • IIS La Fe, Valencia, Spain
  • Department of Internal Medicine, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
  • Department of Allergy and Immunology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
  • Department of Dermatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
  • Department of Pathology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
  • Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taiwan
  • Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan
  • Serviço de Imunoalergologia, Centro Hospitalar de São João E.P.E., Porto, Portugal
  • Laboratório de Imunologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal
  • Centro Hospitalar de São João, Porto, Portugal
  • Federal University of São Paulo, São Paulo, Brazil
  • Federal University of Rio de Janeiro, Rio De Janeiro, Brazil
  • Pontificia Universidade Católica de Campinas, Campinas, Brazil
  • Private Practice, Goiania, Brazil
  • Ege University Medical Faculty, Izmir, Turkey
  • Hospital Central de la Defensa, IMIDEF, Madrid, Spain
  • Centro Hospitalar de Lisboa Central, Hospital de Dona Estefânia, Lisbon, Portugal
  • Faculty of Medicine, University hospital, University of Monastir, Monastir, Tunisia
  • Faculty of Medicine and Health Sciences, Department of Immunology, Allergology, Rheumatology and Antwerp University Hospital, Immunology, Allergology, Rheumatology, University of Antwerp, Antwerp, Belgium
  • IRCCS Oasi Maria S.S., Troina, Italy
  • Immunoallergy Department - Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Faculdade de Medicina de Lisboa, Lisbon, Portugal
  • Serviço de Imunoalergologia, Hospital de São Bernardo, Setúbal, Portugal
  • Hospital de S.Bernardo, Centro Hospitalar de Setúbal, Setúbal, Portugal
  • CUF Descobertas Hospital, Lisbon, Portugal
  • Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK
  • Institute of Pediatrics, Obstetrics and Gynaecology, Kiev, Ukraine
  • Diater Laboratorios, Madrid, Spain
  • Universidad Nacional de Colombia, Cartagena, Colombia
  • Allergy Unit, Hospital Central Cruz Roja, Madrid, Spain
  • AOU careggi, Florence, Italy
  • Department of Internal Medicine, Florence, Italy
  • University Hospital Zagreb, Zagreb, Croatia
  • Yokohama City University Graduate School of Medicine, Yokohama, Japan
  • Jeju National University School of Medicine, Jeju, South Korea
  • Allergy and Clinical Immunology Department, Coimbra University Hospital Center, Coimbra, Portugal
  • Allergy and Clinical Immunology Consult, Leiria Hospital Center, Leiria, Portugal
  • Coimbra University Hospital Centre, Coimbra, Portugal
  • State Hospital 52, Moscow, Russia
  • Clínica Universidad de Navarra, Pamplona, Spain
  • Clinica Universidad de Navarra, Pamplona, Spain
  • La Paz Hospital, Madrid, Spain
  • Allergy Department, La Paz Hospital Institute for Health Research (IdiPAZ), Madrid, Spain
  • Allergy Unit, Department of Dermatology, University Hospital Basel, Basel, Switzerland
  • Drug Allergy Diagnostics Centre, Institute of Paediatrics, Obstetrics and Gynaecology of NAMS, Kiev, Ukraine
  • Allergy Department, La Paz Hospital Institute for Health Research (IdiPAZ), Consorcio Piel en RED, Madrid, Spain
  • Immunology Department, La Paz Hospital Institute for Health Research (IdiPAZ), Consorcio Piel en RED, Madrid, Spain
  • Seoul National University Borame Hospital, Seoul, South Korea
  • Seoul National University Hosptial Healthcare System Gangnam Center, Seoul, South Korea
  • Seoul National University Bundang Hospital, Seongnam, South Korea
  • Seoul National University Hosptial, Seoul, South Korea
  • Seoul National University College of Medicine, Seoul, South Korea
  • Dermatology and Allergy Department, Brabois Hospital, University Hospital of Nancy, Lorraine University, 54500, Vandoeuvre-Lès-Nancy, France
  • Department of Dermatology and Venereology, General Hospital Sibenik, Sibenik, Croatia
  • Dermatology Department, Nicolina Medical Centre, „P. Poni“ Research Institute of Macromolecular Chemistry, Apollonia University, Iasi, Romania
  • Centro Hospitalar Vila Nova Gaia, Vila Nova Gaia, Portugal
  • Department of Dermatology and Venereology, School of Medicine University of Zagreb, University Hospital Center Zagreb, Zagreb, Croatia
  • Department of Pharmacology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
  • University Hospitals Leuven, Leuven, Belgium
  • CIPF, Valencia, Spain
  • Allergy service, Infanta Leonor University Hospital, Madrid, Spain
  • Research Laboratory, IBIMA, Regional University Hospital of Malaga, UMA, Malaga, Spain
  • Allergy Unit, IBIMA-Regional University Hospital of Malaga, University of Malaga, Malaga, Spain
  • Research Unit and Centro de Investigación Biomédica en Red de Enfermedades Respiratorias de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain
  • Allergy Unit, IBIMA, Regional University Hospital of Malaga, UMA, Malaga, Spain
  • Research Laboratory-IBIMA, Málaga, Spain
  • Research Laboratory and Allergy Unit, IBIMA, Regional University Hospital of Malaga, UMA, Malaga, Spain
  • Department of Pharmacology, University of Extremadura, Cáceres, Spain
  • Department of Biochemistry and Molecular Biology, University of Extremadura, Cáceres, Spain
  • Allergy Unit, IBIMA-Regional Hospital of Málaga, Malaga, Spain
  • University of Lorraine and University Hospital Center (CHU) of Nancy, INSERM U-95Faculty of Medicine, Vandoeuvre-Les-Nancy, France
  • Regional Hospital of Málaga, Málaga, Spain
  • University of Liverpool, Liverpool, UK
  • MRC Centre for Drug Safety Science, Department Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
  • Department of Computer Architecture, University of Malaga, Malaga, Spain
  • Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
  • Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
  • Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
  • Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Division of Pediatric Dermatology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  • Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  • Raj Pracha Samasai Institute, Department of disease control, Ministry of Public Health, Nonthaburi, Thailand
  • Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand
  • Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkla, Thailand
  • Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  • Manarom Hospital, Bangkok, Thailand
  • Servicio de Farmacología Clínica, Hospital Universitario La Paz, Madrid, Spain
  • Hospital Universitario La Paz, IdiPAZ, Madrid, Spain
  • Hospital Universitario La Paz, Madrid, Spain
  • Hospital Universitario Ramón y Cajal, Madrid, Spain
  • Hospital Universitario Príncipe de Asturias, Alcalá De Henares, Madrid, Spain
  • Brigham and Women`s Hospital, Division of Rheumatology, Immunology and Allergy, Harvard Medical School, Boston, MA, USA
  • Institute of Immunology and Infectious Diseases, Murdoch University, Perth, Australia
  • Institute for Immunology and Infectious Diseases, Murdoch University, Perth, Australia
  • Vanderbilt University Medical Center, Nashville, TN, USA
  • Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA
  • Hospital Sant’Anna, Como, Italy
  • Department of Allergy, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
  • Universitary General Hospital of Alicante, Alicante, Spain
  • Laboratory of Clinical İmmunology, Department of Microbiology and İmmunology, KU Leuven, Leuven, Belgium
  • Laboratory Medicine, Immunology, University Hospitals, KU Leuven, Leuven, Belgium
  • Pharmacy Service, Hospital Central de la Cruz Roja, Madrid, Spain
  • Department of Organic Chemistry, Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Universidad de Malaga-IBIMA, Malaga, Spain
  • Department of Organic Chemistry, University of Málaga, Malaga, Spain
  • University of Malaga, Malaga, Spain
  • Research Laboratory, IBIMA-Regional University Hospital of Malaga, University of Malaga, Malaga, Spain
  • Odense Research Center for Anaphylaxis, Odense C, Denmark
  • Department of Dermatology and Allergy Center, Odense C, Denmark
  • Odense Research Center for Anaphylaxis, Odense C/Copenhagen, Denmark
  • Department of Dermatology and Allergology, Philipps University Marburg, Marburg, Germany
  • Western University, London, Canada
  • Department of Infectious Diseases, Alfred Health, Melbourne, Australia
  • Department of Dermatology, Osaka University, Osaka, Japan
  • Department of Dermatology, Nara Medical University, Nara, Japan
  • Department of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan
  • Hamamatsu University School of Medicine, Hamamatsu, Japan
  • Shimada City Municipal Hospital, Shimada, Japan
  • University Clinic for Respiratory and Allergic Diseases, Golnik, Slovenia
  • ARSDERMA, Ljubljana, Slovenia
  • Servicio de Alergia, Hospital Universitario La Paz, Madrid, Spain
  • Regional Adult Cystic Fibrosis Unit, St James’s Hospital, Leeds, UK
  • University of Southampton, Southampton, UK
  • Kawasaki Hospital Kawasaki Medical School, Okayama, Japan
  • Kyorin University School of Medicine, Tokyo, Japan
  • Centro Hospitalar de Setúbal, Setúbal, Portugal
  • Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
  • Research Laboratory, IBIMA, Málaga, Spain
  • Inmunology Department, Alfonso X el Sabio University, Madrid, Spain
  • Regional Hospital of Málaga-IBIMA, Málaga, Spain
  • Allergy Unit, IBIMA-Regional University Hospital of Malaga-UMA, Málaga, Spain
  • Research Unit for Allergic Diseases, IBIMA-Regional University Hospital of Malaga-UMA, Málaga, Spain
  • Department for Dermatology and Allergology, University Hospital of Aachen, Aachen, Germany
  • Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia
  • Royal Melbourne Hospital, University of Melbourne, Parkville, Australia
  • AstraZeneca R&D, Cambridge, UK
  • INSERM UMR99, Univ Paris-Sud, University Paris-Saclay, Châtenay-Malabry, France
  • Department of Experimental and Clinical medicine, University of Florence, Florence, Italy
  • UMR CNRS807, Univ Paris-Sud, University Paris-Saclay, Châtenay-Malabry, France
  • Institut de Recherches Internationales Servier, Suresnes, France
  • SIMOPRO, IBiTecS, CEA, Saclay, France
  • INSERM UMR 99, Université Paris-Sud, Châtenay-Malabry, Lyon, France
  • Inserm U1111 - CIRI, Edouard Herriot Hospital, Lyon I University, Lyon, France
  • Inserm U1111 - CIRI, Lyon I University, Lyon, France
  • Inserm U1111 - CIRI, Lyon, France
  • Unité de Thérapie Cellulaire et Génique (UTCG) and URE 004 (ImCelVir), Université Nice Sophia Antipolis, Nice, France
  • Inserm U1111 - CIRI, Lyon-Sud Hospital, Lyon I University, Lyon, France
  • National Yang-Ming University, Taipei, Taiwan
  • Andalusian Centre for Nanomedicine and Biotechnology-BIONAND, Research Laboratory Carlos Haya Hospital-IBIMA, Malaga, Spain
  • Research Laboratory, Regional University Hospital of Malaga, UMA, Malaga, Spain
  • Allergy Service, Carlos Haya Hospital, Malaga, Spain
  • BIONAND, Malaga, Spain
  • Department of Chemical and Physical Biology, Centro de Investigaciones Biológicas-CSIC, Madrid, Spain
  • Pharmacy Unit, Regional University Hospital of Malaga, Malaga, Spain
  • Academia Sinica, Taipei, Taiwan
  • Instituto Politecnico Nacional, Mexico, Mexico
  • Instituto Nacional de Ciencias Medicas y Nutricion, Mexico, Mexico
  • Alergology Service. Hospital Delfos, Barcelona, Spain
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13601-016-0122-y

    DOI

    http://dx.doi.org/10.1186/s13601-016-0122-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008053494


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        "description": "Table of contentsPoster walk 11: miscellaneous drug hypersensitivity 2 (P92\u2013P94, P96\u2013P101)P92 16\u00a0years of experience with proton pump inhibitors (PPIs)Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco Garc\u00eda, Antonio Alvarez, Jose Julio Laguna MartinezP93 Allergy evaluation of quinolone induced adverse reactionsJaume Mart\u00ed Garrido, Carla Tor\u00e1n Barona, Carolina Perales Chorda, Ram\u00f3n L\u00f3pez Salgueiro, Miguel D\u00edaz Palacios, Dolores Hern\u00e1ndez Fern\u00e1ndez De RojasP94 Bupropion-induced acute urticaria and angioedema, a case reportEmre Ali Acar, Ayse Aktas, Aylin T\u00fcrel Ermertcan, Peyker TemizP96 Delayed type hypersensitivity and study of cross-reactivity between proton-pump inhibitorsChien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung ChungP97 Diagnostic work-up in suspected hypersensitivity to proton-pump inhibitors: looking at cross-reactivityFabr\u00edcia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. CernadasP98 Management of infusion-related hypersensitivity reactions to enzyme replacement therapy for lysosomal diseasesLuis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, Jos\u00e9 Francisco Da Silva Franco, Leandra Queiroz, Dirceu Sol\u00e9P99 Management of insulin allergy with continuous subcutaneous insulin infusionCeyda Tunakan Dalgi\u00e7, Ayt\u00fcl Zerrin Sin, Fatma D\u00fcs\u00fcn\u00fcr G\u00fcnsen, G\u00f6kten Bulut, Fatma \u00d6m\u00fcr Ardeniz, Okan G\u00fclbahar, Emine Nihal Mete G\u00f6kmen, Ali KokuludagP100 Off-label use of icatibant for management of serious angioedema associated with angiotensin inhibitorsAna M. Montoro De Francisco, Tal\u00eda M\u00aa De Vicente Jim\u00e9nez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia Garc\u00eda LuqueP101 Thiocolchicoside anaphylaxis: an unusual suspect?Luis Amaral, Fabricia Carolino, Leonor Carneiro Le\u00e3o, Eunice Castro, Josefina CernadasPoster walk 12: betalactam hypersensitivity (P102\u2013P111)P102 A curious delayed reading: a case report of a \u03b2-lactam allergy in a childNicole Pinto, Joana Belo, Jo\u00e3o Marques, Pedro Carreiro-Martins, Paula Leiria-PintoP103 Betalactam-induced hypersensitivity: a 10-years\u2019 experienceAmel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim AouamP104 Cefazolin hypersensitivity: towards optimized diagnosisAstrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito SabatoP105 Clavulanic acid allergy: two cases reportAnabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Louren\u00e7o, Maria-Jo\u00e3o Paes, Am\u00e9lia Sp\u00ednola-Santos, Manuel Pereira-BarbosaP106 Diagnosis of betalactam allergy in an allergy departmentC\u00edntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe In\u00e1cioP107 Diagnostic work-up of 410 patients with suspicion of betalactam antibiotic hypersensitivityFilipe Benito-Garcia, In\u00eas Mota, Magna Correia, \u00c2ngela Gaspar, Marta Chambel, Susana Piedade, M\u00e1rio Morais-AlmeidaP108 Immediate selective hypersensitivity reactions to clavulanic acidAlla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr LapshynP109 Prevalence and incidence of penicillin hypersensitivity reactions in ColombiaPablo Andr\u00e9s Miranda, Bautista De La Cruz HoyosP110 Selective sensitization to amoxicilin and clavulanic acidJose Julio Laguna Martinez, Aranzazu Jimenez Blanco, Javier Dionicio Elera, Cosmin Boteanu, Rosario Gonzalez-Mendiola, Marta Del PozoP111 Infliximab-specific T cells are detectable also in treated patients who have not developed anti-drug antibodiesAlessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico MaggiPoster walk 13: biologicals, local anesthetics, others (P112\u2013P118)P112 A case report of allergic immediate systemic reaction to adalimumab and certolizumabCeyda Tunakan Dalgi\u00e7, Fatma D\u00fcs\u00fcn\u00fcr G\u00fcnsen, G\u00f6kten Bulut, Fatma \u00d6m\u00fcr Ardeniz, Okan G\u00fclbahar, Emine Nihal Mete G\u00f6kmen, Ayt\u00fcl Zerrin Sin, Ali KokuludagP113 Allergy to local anesthetics: negative predictive value of skin testsIvana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta SimicP114 Cutaneous adverse reactions of molecular targeted agents: a retrospective analysis in 150 patients in our departmentYukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko AiharaP115 Generalized paralysis induced by local lidocaine injectionJaechun Jason Lee, Jay Chol Choi, Hwa Young LeeP116 Hypersensitivity to local anaesthetics: a 10\u00a0year reviewRosa-Anita Rodrigues Fernandes, Em\u00edlia Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo BomP117 Local anaesthetics: a rare culprit in hypersensitivity reactionsAna Rodolfo, Eunice Dias-Castro, Josefina CernadasP118 Stevens\u2013Johnson syndrome in clinical practice: a variant of clinical courseMarina VoronovaPoster walk 14: RCM (P119\u2013P128)P119 13 cases of severe anaphylactic reactions due to radiocontrast mediaJaume Mart\u00ed Garrido, Ramon Lopez Salgueiro, Diana Kury Valle, Ver\u00f3nica Pacheco Coronel, Carolina Perales Chord\u00e1, Dolores Hernandez Fernandez De RojasP120 Anaphylactic shock after administration of iodinated contrast medium during cardiac catheterizationRoselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D\u2019Amelio, Amalia Bernad, Olga Vega, Gabriel GastaminzaP121 Anaphylactic shock and cardiac arrest induced by gadolinium-based contrast agentsBeatriz Pola Bibi\u00e1n, Marina Lluncor Salazar, Gemma Vil\u00e0 Nadal, Ana Mar\u00eda Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Mu\u00f1oz, Santiago Quirce Gancedo, Maria Rosario Caba\u00f1as MorenoP122 Anaphylaxis to gadobenate and cross-reactivity to other gadolinium-based contrast agents in two patientsKathrin Scherer HofmeierP123 Anaphylaxis to glatiramer acetate in a patient with multiple sclerosisFabr\u00edcia Carolino, Vladyslava Barzylovych, Josefina R. CernadasP124 Delayed hypersensitivity reaction to radiocontrast mediaFabr\u00edcia Carolino, Diana Silva, Leonor Le\u00e3o, Josefina R. CernadasP125 Drug reaction with eosinophilia and systemic symptoms induced by iodixanolGemma Vil\u00e0-Nadal, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bell\u00f3n, Javier Dom\u00ednguez, Santiago QuirceP126 Electronic consultation support system for radiocontrast media hypersensitivity changes clinician\u2019s behaviorMin-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok ChangP127 Hypersensitivity reactions to iodinated contrast media: skin testing and follow-upDanica Juricic Nahal, Ivana Cegec, Viktorija Erdeljic Turk, Iva Kraljickovic, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iveta SimicP128 Would iodine allergy exist?Cl\u00e9mence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick BarbaudPoster walk 15: MPE/type 4 (P129\u2013P137)P129 Delayed hypersensitivity cutaneous reactions: a case/control study from a tunisian databaseKarim Aouam, Najah Ben Fadhel, Zohra Chadly, Nadia Ben Fredj, Naceur A. Boughattas, Amel ChaabaneP130 Delayed hypersensitivity reactions to cephalosporins: a review of seven casesJoana Cosme, Anabela Lopes, Am\u00e9lia Sp\u00ednola-Santos, Manuel Pereira-BarbosaP131 Diclofenac induced allergic contact dermatitis: case series of four patientsSandra Jerkovic Gulin, Anca ChiriacP132 Late-onset maculopapular rash to irbesartanB\u00e1rbara Kong Cardoso, Elza Tomaz, Regina Viseu, Filipe In\u00e1cioP133 Nonimmediate hypersensitivity reactions to betalactams: a retrospective analysisAna Moreira, Susana Cadinha, Ana Castro Neves, Patricia Barreira, Daniela Malheiro, J. P. Moreira Da SilvaP134 Occupational airborne contact dermatitis to omeprazoleRu\u017eica Jurakic-Toncic, Suzana Ljubojevic, Petra TurcicP135 Ornidazole-induced fixed drug eruption confirmed by positive patch test on a residual pigmented lesionLiesbeth Gilissen, Sara Huygens, An GoossensP136 Repeated delayed reaction induced by amoxicillin and amoxicillin clavulanateInmaculada Andreu, Ramon Lopez-Salgueiro, Alicia Martinez Romero, Pau Gomez CabezasP137 Systemic photosensitivity from fenofibrate in a patient photo-sensitized to ketoprofenLiesbeth Gilissen, An GoossensPoster walk 16: HLA genetics (P138\u2013P146)P138 A copy number variation in ALOX5 and PTGER1 is associated with nonsteroidal anti-inflammatory drugs induced urticaria and/or angioedemaPedro Ayuso Parejo, Maria Del Carmen Plaza-Ser\u00f3n, Inmaculada Do\u00f1a, Natalia Blanca L\u00f3pez, Carlos Flores, Luisa Galindo, Ana Molina, James Richard Perkins, Jose Antonio Cornejo-Garc\u00eda, Jos\u00e9 Augusto Garc\u00eda-Ag\u00fandez, Elena Garc\u00eda-Mart\u00edn, Paloma Campo, Mar\u00eda Gabriela Canto, Miguel BlancaP139 Association of galectin-3 (LGALS3) single nucleotide polymorphisms with non-steroidal anti-inflammatory drugs-induced urticaria/angioedemaJos\u00e9 Antonio Cornejo-Garcia, Inmaculada Do\u00f1a, Rosa Mar\u00eda Gu\u00e9ant-Rodr\u00edguez, Natalia Blanca-L\u00f3pez, Mar\u00eda Carmen Plaza-Ser\u00f3n, Raquel Jurado-Escobar, Esther Barrionuevo, Mar\u00eda Salas, Mar\u00eda Luisa Galindo, Gabriela Canto, Miguel Blanca, Jean-Louis Gu\u00e9antP140 Detection of T cell responses to ticlopidine using peripheral blood mononuclear cells from HLA-A*33:03+ healthy donorsToru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. NaisbittP141 Epistasis approaches to identify novel genes potentially involved in NSAIDs hypersensitivityJames Richard Perkins, Jose Antonio Cornejo Garc\u00eda, Oswaldo Trelles, Inmaculada Do\u00f1a, Esther Barrionuevo, Mar\u00eda Salas, Mar\u00eda Auxiliadora Guerrero, Miguel Blanca, Alex UptonP142 Genetic predisposition of cold medicine related SJS/TEN with severe ocular complicationsMayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru KinoshitaP143 HLA-B*13:01 and dapsone induced hypersensitivity in Thai populationChonlaphat Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong KlaewsongkramP144 HLA-B*15:02 alleles and lamotrigine-induced cutaneous adverse drug reactions in ThaiChonlaphat Sukasem, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. TheeramokeP145 HLA-B*38:01 and HLA-A*24:02 allele frequencies in Spanish patients with lamotrigine-induced SCARsTeresa Bell\u00f3n, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Casta\u00f1er, Francisco Jos\u00e9 De AbajoP146 Overrepresentation of a class II HLA haplotype in severe hypersensitivity type I reactions to carboplatinVioleta R\u00e9gnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana CastellsPoster walk 17: in vivo diagnosis\u00a0+\u00a0sIgE (P147\u2013P154)P147 Absence of specific Ig-e against beta-lactams 9\u00a0months after an allergic reaction to amoxicillin-clavulanic acidElisa Boni, Marina Russello, Marina MauroP148 Drug provocation tests in suspected opioid allergyKok Loong Ue, Krzysztof RutkowskiP149 Improvement to the specific IgE cut-off in the assess of \u03b2-lactamic allergyVictor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cant\u00f3 Reig, Javier Fernandez SanchezP150 Initial false negative specific IgE to gelatin in a patient with gelatin-induced anaphylaxisChristine Breynaert, Erna Van Hoeyveld, Rik SchrijversP151 Inmediate reactions to beta-lactam antibiotics: pattern of skin test response over the timeJose Julio Laguna Martinez, Rosario Gonzalez Mendiola, Javier Dionicio Elera, Cosmin Boteanu, Aranzazu Jimenez Blanco, Marta Del Pozo, Raquel Fuentes IrigoyenP152 New fluorescent dendrimeric antigens for the evaluation of dendritic cell maturation as a test to detect allergy reactions to amoxicillinDaniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, Mar\u00eda Jos\u00e9 Torres, Miguel BlancaP153 Positive skin test or positive specific IgE to penicillin does not predict penicillin allergyLine K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-JensenP154 Significance of skin testing and in vitro-analysis of neuromuscular blocking agents in diagnosis of perioperative drug hypersensitivity: evaluation of a negative control populationWolfgang Pf\u00fctzner, Hannah D\u00f6rnbach, Johanna Visse, Michele Rauber, Christian M\u00f6bsPoster walk 18: in vitro/ex vivo (P155\u2013P158, P160\u2013P164)P155 Diagnostic value of the lymphocyte toxicity assay (LTA) and the in vitro platelet toxicity assay (IPTA) for \u03b2-lactam allergyAbdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. RiederP156 Enzyme linked immunospot assay used in the diagnosis of severe cutaneous adverse reactions to antimicrobialsAlec Redwood, Jason Trubiano, Rebecca Pavlos, Emily Woolnough, Kaija Stautins, Christina Cheng, Elizabeth PhillipsP157 Evaluation of in vitro diagnostic methods for identifying the culprit drugs in drug hypersensitivityKenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro KatayamaP158 Ex-vivo expanded skin-infiltrating T cells from severe drug eruptions are reactive with causative drugs: a possible novel method for determination of causative drugsToshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki TokuraP160 In vitro release of IL-2, IL-5 and IL-13 in diagnosis of patients with delayed-type nickel hypersensitivityMira Silar, Mihaela Zidarn, Helena Rupnik, Peter KorosecP161 Single cell analysis of drug responsive T cells; identification of candidate drug reactive T cell receptors in abacavir and carbamazepine hypersensitivityAlec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Rebecca Pavlos, Simon Mallal, Elizabeth PhillipsP162 Specificity and sensitivity of LTT in DRESS: analysis of agreement with the Spanish pharmacovigilance system probability algorithmRosario Caba\u00f1as, Elena Ramirez, Ana Mar\u00eda Fiandor, Teresa Bell\u00f3nP163 The role of interleukin-22 in \u03b2-lactam hypersensitivityAndrew Sullivan, Paul Whitaker, Daniel Peckham, B. Kevin Park, Dean J. NaisbittP164 Vancomycin-specific T cell responses and teicoplanin cross-reactivityWei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-JonesPoster walk 19: BAT and biomarkers (P165\u2013P173)P165 A combination of early biomarkers useful for the prediction of severe ADRsYumi Aoyama, Tetsuo ShioharaP166 Basophil activation test in the diagnostic approach of reactions during general anaesthesiaAna Moreira, Susana Cadinha, Patr\u00edcia Barreira, Ana Castro Neves, Daniela Malheiro, Sara Correia, J. P. Moreira Da SilvaP167 IL-10 can be related to successful desensitizationAsli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin \u00c7atin-Aktas, Gunnur DenizP168 Immediate reactions to proton pump inhibitors: value of basophil activation testMaria Salas, Jose Julio Laguna, Esther Barrionuevo, J. Dionicio, Tahia Fernandez, R. Gonzalez-Mendiola, I. Olazabal, Maria Dolores Ruiz, Miguel Blanca, Cristobalina Mayorga, Maria Jos\u00e9 TorresP169 Improvement of the elevated tryptase criterion to discriminate IgE from non-IgE mediated allergic reactionsGabriel Gastaminza, Alberto Lafuente, Carmen D\u2019Amelio, Amalia Bernad, Olga Vega, Roselle Catherine Madamba, M. Jose Goikoetxea, Marta Ferrer, Jorge N\u00fa\u00f1ezP170 Low expression of Tim-3 could serve as a biomarker for control and diagnose maculopapular exanthema induced by drugsTahia Diana Fern\u00e1ndez, Inmaculada Do\u00f1a, Francisca Palomares, Rub\u00e9n Fern\u00e1ndez, Maria Salas, Esther Barrionuevo, Maria Isabel Sanchez, Miguel Blanca, Maria Jos\u00e9 Torres, Cristobalina MayorgaP171 Role of basophil activation test using two different activation markers for the diagnosis of allergy to fluoroquinolonesEsther Barrionuevo, Tah\u00eda Fernandez, Arturo Ruiz, Adriana Ariza, Maria Salas, Inmaculada Do\u00f1a, Ana Molina, Miguel Blanca, Maria Jose Torres, Cristobalina MayorgaP172 The importance of basophil activation test in anaphylaxis due to celecoxibAmalia Bernad Alonso, Carmen D\u2019Amelio Gar\u00f3falo, Olga Vega Matute, Marta Ferrer Puga, Mar\u00eda Jos\u00e9 Goikoetxea Lapresa, Roselle Catherine Yu Madamba, Gabriel Gastaminza LasarteP173 The role of basophil activation test in the diagnosis of immediate type drug hypersensitivity to betalactam antibioticsAntonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina BalakirskiPoster walk 20: TCR recognition, cellular (P174\u2013P183)P174 Characterisation of the effect of co-inhibitory signalling on the activation of drug-derived antigen-specific T-cellsAndrew Gibson, Monday Ogese, Lee Faulkner, B. Kevin Park, Dean J. NaisbittP175 Characterization of drug hapten-specific T cell responses in piperacillin hypersensitive patientsZaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, Paul Whitaker, Daniel Peckham, Lee Faulkner, John Farrel, Kevin Park, Dean NaisbittP176 Characterization of the response of T-cells to telaprevir and its metabolite in normal volunteersZaid Al-Attar, Khetam Alhilali, Yanni Xue, John Farrell, Lee Faulkner, Kevin Park, Dean NaisbittP177 Characterization of the T cell receptor signatures of drug-responsive T cellsPatricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony PurcellP178 Defining the signals between hepatocytes and immune cells in idiosyncratic drug-induced liver injury (DILI)Monday O. Ogese, Lee Faulkner, B. Kevin Park, Catherine Betts, Dean J. NaisbittP179 Development of novel chemicals that do not bind to HLA-B*57:01 or activate CD8\u00a0+\u00a0T-cells through modification of the 6-amino cyclopropyl group of abacavirPaul Thomson, John Farrell, Mohammad Alhaidari, Neill Berry, Paul M. O\u2019Neill, B. Kevin Park, Dean J. NaisbittP180 Generation and characterization of dapsone- and nitroso-dapsone-specific T-cell clones using lymphocytes from healthy volunteersAbdulaziz Alzahrani, Monday O. Ogese, John Farrell, Lee Faulkner, Andrew Gibson, Arun Tailor, B. Kevin Park, Dean J. NaisbittP181 Identification of benzylpenicillin-hapten peptides responsible for na\u00efve T-cell activation and immunization of allergic patients to penicillinMarie Eliane Azoury, Lucia Fili, Rami Bechara, No\u00e9mie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc PallardyP182 Massive expansion of clonotypic and polycytotoxic CD8+ T cells in toxic epidermal necrolysisAxel Patrice Villani, Aurore Rozi\u00e8res, Beno\u00eet Bensa\u00efd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Marc Pallardy, Janet Maryanski, Jean-Fran\u00e7ois Nicolas, Osami Kanagawa, Marc VocansonP183 Pharmaco-immunological synapse of HLA-drug-TCR in SCARShuen-Iu HungPoster walk 21: new in vitro methods, haptens, etc. (P184\u2013P194)P184 Amoxicillin-clavulanate forms distinct multiple haptenic structures on human serum albumin in patientsXiaoli Meng, Arun Tailor, Caroline J. Harrison, Rosalind E. Jenkins, Paul Whitaker, Neil S. French, Dean J. Naisbitt, B. Kevin ParkP185 Dendrimeric antigens for studying the influence of penicillin determinants orientation on IgE recognitionMaria Isabel Monta\u00f1ez, Cristobalina Mayorga, Francisco Najera, Adriana Ariza, Tahia D. Fernandez, Maria Salas, Angela Martin-Serrano, Miguel Blanca, Ezequiel Perez-Inestrosa, Maria Jose TorresP186 Dendrimeric antigens on solid supports: designed materials for IgE quantificationYolanda Vida, Maria Isabel Monta\u00f1ez, Noemi Molina, Daniel Collado, Francisco Najera, Adriana Ariza, Maria Jose Torres, Cristobalina Mayorga, Ezequiel Perez-InestrosaP187 Development of a screening assay for drug hypersensitivity using na\u00efve T cells from donors with seven different HLA class I risk allelesLee Faulkner, Sally Wood, Ana Alfirevic, Munir Pirmohamed, Dean J. Naisbitt, B. Kevin ParkP188 Different patterns of recognition of structures derived from amoxicillin by IgE antibodies from patients with immediate hypersensitivity reactions to betalactamsAdriana Ariza, Cristobalina Mayorga, Mar\u00eda Isabel Monta\u00f1ez, Mar\u00eda Salas, Inmaculada Do\u00f1a, \u00c1ngela Mart\u00edn-Serrano, Ezequiel P\u00e9rez-Inestrosa, Dolores P\u00e9rez-Sala, Miguel Blanca, Antonio E. Guzm\u00e1n, Mar\u00eda Jos\u00e9 TorresP189 High-resolution typing of HLA polymorphism and T-cell receptor repertoire for severe adverse drug reactions based on the cost-effective next-generation sequencing approachesTai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn WuP190 Identification and fate of intracellular proteins haptenated by amoxicillinFrancisco J. S\u00e1nchez-G\u00f3mez, Juan M. Gonz\u00e1lez-Morena, Yolanda Vida, Ezequiel P\u00e9rez-Inestrosa, Miguel Blanca, Mar\u00eda J. Torres, Dolores P\u00e9rez-SalaP191 In vitro detection of terbinafine protein adductsArun Tailor, Toru Usui, Yanni Xue, Xiaoli Meng, Dean J. Naisbitt, B. Kevin ParkP192 MicroRNAs dysregulation in PBMCs from drug hypersensitivity patients during drug challenge in vitroAlejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Dean J. Naisbitt, Noe Valentin Duran Figueroa, Jose Luis Castrejon FloresP193 NSAIDs-exacerbated cutaneous disease: high throughput gene expression profilingJos\u00e9 Antonio Cornejo-Garc\u00eda, James Perkins, Natalia Blanca-L\u00f3pez, Diana P\u00e9rez-Alzate, Raquel Jurado-Escobar, Inmaculada Do\u00f1a, Gador Bogas, Mar\u00eda J. Torres, Gabriela Canto, Miguel BlancaP194 Utility of skin tests in non-immediate reactions to amoxicillinLuis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiago", 
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          "Lopes", 
          "Cosme", 
          "Arriba", 
          "Ferrer", 
          "characterisation", 
          "dendrimeric", 
          "Blanco", 
          "French", 
          "RCM", 
          "Watanabe", 
          "Kato", 
          "Lopez", 
          "Belo", 
          "Cruz", 
          "weavers", 
          "Fatma", 
          "Barreiras", 
          "Pozo", 
          "Pinto", 
          "Betts", 
          "Merk", 
          "FERRE", 
          "Lacerda", 
          "Caba\u00f1as", 
          "Ribeiro", 
          "Coskun", 
          "Perkins", 
          "prediction", 
          "Farrell", 
          "Torres", 
          "dos Reis", 
          "UE", 
          "Choi", 
          "Casta\u00f1er", 
          "Faria", 
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          "Meng", 
          "Kwan", 
          "Cantos", 
          "Guerrero", 
          "Alvarez", 
          "Marti", 
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          "Chang", 
          "PAE", 
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          "Palacios", 
          "Amaral", 
          "ITO", 
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          "Harrison", 
          "Reig", 
          "Correia", 
          "Rodriguez", 
          "Aguiar", 
          "Lee", 
          "Kang", 
          "Barona", 
          "Nunes", 
          "Campos", 
          "tens", 
          "Pavlos", 
          "Laguna", 
          "Chen", 
          "Woolnough", 
          "Jenkins", 
          "Figueroa", 
          "Garrido", 
          "Polak", 
          "Aranda", 
          "solid support", 
          "Nicolas", 
          "Boni", 
          "Palomares", 
          "ODA", 
          "Romero", 
          "Real", 
          "Sanchez", 
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          "Cheng", 
          "Castro", 
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          "J. Harrison", 
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          "wood", 
          "Phillips", 
          "corona", 
          "Ortega", 
          "Cardoso", 
          "Alonso", 
          "Pimentel", 
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          "Tanegashima", 
          "Salazar", 
          "L\u00f3pez", 
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          "Gaspar", 
          "Galindo", 
          "Faulkner", 
          "Thomson", 
          "Franco", 
          "Romans", 
          "Villani", 
          "McKinnon", 
          "SILAR", 
          "NHIM", 
          "system probability", 
          "Puga", 
          "Huygens", 
          "O\u2019Neill", 
          "Guzm\u00e1n", 
          "Boga", 
          "Bulut", 
          "de Francisco", 
          "Nahal", 
          "Rodolfo", 
          "Delahaye", 
          "Santon", 
          "Russello", 
          "Gomis", 
          "Alhaidari", 
          "Richard Weaver", 
          "Maryanski"
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    4005 TRIPLES      20 PREDICATES      602 URIs      594 LITERALS      6 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s13601-016-0122-y schema:about anzsrc-for:11
    2 anzsrc-for:1107
    3 schema:author N1976cb787aec4586a2063258b2d8051a
    4 schema:datePublished 2016-08-25
    5 schema:datePublishedReg 2016-08-25
    6 schema:description Table of contentsPoster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101)P92 16 years of experience with proton pump inhibitors (PPIs)Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna MartinezP93 Allergy evaluation of quinolone induced adverse reactionsJaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De RojasP94 Bupropion-induced acute urticaria and angioedema, a case reportEmre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan, Peyker TemizP96 Delayed type hypersensitivity and study of cross-reactivity between proton-pump inhibitorsChien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung ChungP97 Diagnostic work-up in suspected hypersensitivity to proton-pump inhibitors: looking at cross-reactivityFabrícia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. CernadasP98 Management of infusion-related hypersensitivity reactions to enzyme replacement therapy for lysosomal diseasesLuis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, José Francisco Da Silva Franco, Leandra Queiroz, Dirceu SoléP99 Management of insulin allergy with continuous subcutaneous insulin infusionCeyda Tunakan Dalgiç, Aytül Zerrin Sin, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Ali KokuludagP100 Off-label use of icatibant for management of serious angioedema associated with angiotensin inhibitorsAna M. Montoro De Francisco, Talía Mª De Vicente Jiménez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia García LuqueP101 Thiocolchicoside anaphylaxis: an unusual suspect?Luis Amaral, Fabricia Carolino, Leonor Carneiro Leão, Eunice Castro, Josefina CernadasPoster walk 12: betalactam hypersensitivity (P102–P111)P102 A curious delayed reading: a case report of a β-lactam allergy in a childNicole Pinto, Joana Belo, João Marques, Pedro Carreiro-Martins, Paula Leiria-PintoP103 Betalactam-induced hypersensitivity: a 10-years’ experienceAmel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim AouamP104 Cefazolin hypersensitivity: towards optimized diagnosisAstrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito SabatoP105 Clavulanic acid allergy: two cases reportAnabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Lourenço, Maria-João Paes, Amélia Spínola-Santos, Manuel Pereira-BarbosaP106 Diagnosis of betalactam allergy in an allergy departmentCíntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe InácioP107 Diagnostic work-up of 410 patients with suspicion of betalactam antibiotic hypersensitivityFilipe Benito-Garcia, Inês Mota, Magna Correia, Ângela Gaspar, Marta Chambel, Susana Piedade, Mário Morais-AlmeidaP108 Immediate selective hypersensitivity reactions to clavulanic acidAlla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr LapshynP109 Prevalence and incidence of penicillin hypersensitivity reactions in ColombiaPablo Andrés Miranda, Bautista De La Cruz HoyosP110 Selective sensitization to amoxicilin and clavulanic acidJose Julio Laguna Martinez, Aranzazu Jimenez Blanco, Javier Dionicio Elera, Cosmin Boteanu, Rosario Gonzalez-Mendiola, Marta Del PozoP111 Infliximab-specific T cells are detectable also in treated patients who have not developed anti-drug antibodiesAlessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico MaggiPoster walk 13: biologicals, local anesthetics, others (P112–P118)P112 A case report of allergic immediate systemic reaction to adalimumab and certolizumabCeyda Tunakan Dalgiç, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Aytül Zerrin Sin, Ali KokuludagP113 Allergy to local anesthetics: negative predictive value of skin testsIvana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta SimicP114 Cutaneous adverse reactions of molecular targeted agents: a retrospective analysis in 150 patients in our departmentYukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko AiharaP115 Generalized paralysis induced by local lidocaine injectionJaechun Jason Lee, Jay Chol Choi, Hwa Young LeeP116 Hypersensitivity to local anaesthetics: a 10 year reviewRosa-Anita Rodrigues Fernandes, Emília Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo BomP117 Local anaesthetics: a rare culprit in hypersensitivity reactionsAna Rodolfo, Eunice Dias-Castro, Josefina CernadasP118 Stevens–Johnson syndrome in clinical practice: a variant of clinical courseMarina VoronovaPoster walk 14: RCM (P119–P128)P119 13 cases of severe anaphylactic reactions due to radiocontrast mediaJaume Martí Garrido, Ramon Lopez Salgueiro, Diana Kury Valle, Verónica Pacheco Coronel, Carolina Perales Chordá, Dolores Hernandez Fernandez De RojasP120 Anaphylactic shock after administration of iodinated contrast medium during cardiac catheterizationRoselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D’Amelio, Amalia Bernad, Olga Vega, Gabriel GastaminzaP121 Anaphylactic shock and cardiac arrest induced by gadolinium-based contrast agentsBeatriz Pola Bibián, Marina Lluncor Salazar, Gemma Vilà Nadal, Ana María Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Muñoz, Santiago Quirce Gancedo, Maria Rosario Cabañas MorenoP122 Anaphylaxis to gadobenate and cross-reactivity to other gadolinium-based contrast agents in two patientsKathrin Scherer HofmeierP123 Anaphylaxis to glatiramer acetate in a patient with multiple sclerosisFabrícia Carolino, Vladyslava Barzylovych, Josefina R. CernadasP124 Delayed hypersensitivity reaction to radiocontrast mediaFabrícia Carolino, Diana Silva, Leonor Leão, Josefina R. CernadasP125 Drug reaction with eosinophilia and systemic symptoms induced by iodixanolGemma Vilà-Nadal, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bellón, Javier Domínguez, Santiago QuirceP126 Electronic consultation support system for radiocontrast media hypersensitivity changes clinician’s behaviorMin-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok ChangP127 Hypersensitivity reactions to iodinated contrast media: skin testing and follow-upDanica Juricic Nahal, Ivana Cegec, Viktorija Erdeljic Turk, Iva Kraljickovic, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iveta SimicP128 Would iodine allergy exist?Clémence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick BarbaudPoster walk 15: MPE/type 4 (P129–P137)P129 Delayed hypersensitivity cutaneous reactions: a case/control study from a tunisian databaseKarim Aouam, Najah Ben Fadhel, Zohra Chadly, Nadia Ben Fredj, Naceur A. Boughattas, Amel ChaabaneP130 Delayed hypersensitivity reactions to cephalosporins: a review of seven casesJoana Cosme, Anabela Lopes, Amélia Spínola-Santos, Manuel Pereira-BarbosaP131 Diclofenac induced allergic contact dermatitis: case series of four patientsSandra Jerkovic Gulin, Anca ChiriacP132 Late-onset maculopapular rash to irbesartanBárbara Kong Cardoso, Elza Tomaz, Regina Viseu, Filipe InácioP133 Nonimmediate hypersensitivity reactions to betalactams: a retrospective analysisAna Moreira, Susana Cadinha, Ana Castro Neves, Patricia Barreira, Daniela Malheiro, J. P. Moreira Da SilvaP134 Occupational airborne contact dermatitis to omeprazoleRužica Jurakic-Toncic, Suzana Ljubojevic, Petra TurcicP135 Ornidazole-induced fixed drug eruption confirmed by positive patch test on a residual pigmented lesionLiesbeth Gilissen, Sara Huygens, An GoossensP136 Repeated delayed reaction induced by amoxicillin and amoxicillin clavulanateInmaculada Andreu, Ramon Lopez-Salgueiro, Alicia Martinez Romero, Pau Gomez CabezasP137 Systemic photosensitivity from fenofibrate in a patient photo-sensitized to ketoprofenLiesbeth Gilissen, An GoossensPoster walk 16: HLA genetics (P138–P146)P138 A copy number variation in ALOX5 and PTGER1 is associated with nonsteroidal anti-inflammatory drugs induced urticaria and/or angioedemaPedro Ayuso Parejo, Maria Del Carmen Plaza-Serón, Inmaculada Doña, Natalia Blanca López, Carlos Flores, Luisa Galindo, Ana Molina, James Richard Perkins, Jose Antonio Cornejo-García, José Augusto García-Agúndez, Elena García-Martín, Paloma Campo, María Gabriela Canto, Miguel BlancaP139 Association of galectin-3 (LGALS3) single nucleotide polymorphisms with non-steroidal anti-inflammatory drugs-induced urticaria/angioedemaJosé Antonio Cornejo-Garcia, Inmaculada Doña, Rosa María Guéant-Rodríguez, Natalia Blanca-López, María Carmen Plaza-Serón, Raquel Jurado-Escobar, Esther Barrionuevo, María Salas, María Luisa Galindo, Gabriela Canto, Miguel Blanca, Jean-Louis GuéantP140 Detection of T cell responses to ticlopidine using peripheral blood mononuclear cells from HLA-A*33:03+ healthy donorsToru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. NaisbittP141 Epistasis approaches to identify novel genes potentially involved in NSAIDs hypersensitivityJames Richard Perkins, Jose Antonio Cornejo García, Oswaldo Trelles, Inmaculada Doña, Esther Barrionuevo, María Salas, María Auxiliadora Guerrero, Miguel Blanca, Alex UptonP142 Genetic predisposition of cold medicine related SJS/TEN with severe ocular complicationsMayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru KinoshitaP143 HLA-B*13:01 and dapsone induced hypersensitivity in Thai populationChonlaphat Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong KlaewsongkramP144 HLA-B*15:02 alleles and lamotrigine-induced cutaneous adverse drug reactions in ThaiChonlaphat Sukasem, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. TheeramokeP145 HLA-B*38:01 and HLA-A*24:02 allele frequencies in Spanish patients with lamotrigine-induced SCARsTeresa Bellón, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Castañer, Francisco José De AbajoP146 Overrepresentation of a class II HLA haplotype in severe hypersensitivity type I reactions to carboplatinVioleta Régnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana CastellsPoster walk 17: in vivo diagnosis + sIgE (P147–P154)P147 Absence of specific Ig-e against beta-lactams 9 months after an allergic reaction to amoxicillin-clavulanic acidElisa Boni, Marina Russello, Marina MauroP148 Drug provocation tests in suspected opioid allergyKok Loong Ue, Krzysztof RutkowskiP149 Improvement to the specific IgE cut-off in the assess of β-lactamic allergyVictor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cantó Reig, Javier Fernandez SanchezP150 Initial false negative specific IgE to gelatin in a patient with gelatin-induced anaphylaxisChristine Breynaert, Erna Van Hoeyveld, Rik SchrijversP151 Inmediate reactions to beta-lactam antibiotics: pattern of skin test response over the timeJose Julio Laguna Martinez, Rosario Gonzalez Mendiola, Javier Dionicio Elera, Cosmin Boteanu, Aranzazu Jimenez Blanco, Marta Del Pozo, Raquel Fuentes IrigoyenP152 New fluorescent dendrimeric antigens for the evaluation of dendritic cell maturation as a test to detect allergy reactions to amoxicillinDaniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, María José Torres, Miguel BlancaP153 Positive skin test or positive specific IgE to penicillin does not predict penicillin allergyLine K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-JensenP154 Significance of skin testing and in vitro-analysis of neuromuscular blocking agents in diagnosis of perioperative drug hypersensitivity: evaluation of a negative control populationWolfgang Pfützner, Hannah Dörnbach, Johanna Visse, Michele Rauber, Christian MöbsPoster walk 18: in vitro/ex vivo (P155–P158, P160–P164)P155 Diagnostic value of the lymphocyte toxicity assay (LTA) and the in vitro platelet toxicity assay (IPTA) for β-lactam allergyAbdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. RiederP156 Enzyme linked immunospot assay used in the diagnosis of severe cutaneous adverse reactions to antimicrobialsAlec Redwood, Jason Trubiano, Rebecca Pavlos, Emily Woolnough, Kaija Stautins, Christina Cheng, Elizabeth PhillipsP157 Evaluation of in vitro diagnostic methods for identifying the culprit drugs in drug hypersensitivityKenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro KatayamaP158 Ex-vivo expanded skin-infiltrating T cells from severe drug eruptions are reactive with causative drugs: a possible novel method for determination of causative drugsToshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki TokuraP160 In vitro release of IL-2, IL-5 and IL-13 in diagnosis of patients with delayed-type nickel hypersensitivityMira Silar, Mihaela Zidarn, Helena Rupnik, Peter KorosecP161 Single cell analysis of drug responsive T cells; identification of candidate drug reactive T cell receptors in abacavir and carbamazepine hypersensitivityAlec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Rebecca Pavlos, Simon Mallal, Elizabeth PhillipsP162 Specificity and sensitivity of LTT in DRESS: analysis of agreement with the Spanish pharmacovigilance system probability algorithmRosario Cabañas, Elena Ramirez, Ana María Fiandor, Teresa BellónP163 The role of interleukin-22 in β-lactam hypersensitivityAndrew Sullivan, Paul Whitaker, Daniel Peckham, B. Kevin Park, Dean J. NaisbittP164 Vancomycin-specific T cell responses and teicoplanin cross-reactivityWei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-JonesPoster walk 19: BAT and biomarkers (P165–P173)P165 A combination of early biomarkers useful for the prediction of severe ADRsYumi Aoyama, Tetsuo ShioharaP166 Basophil activation test in the diagnostic approach of reactions during general anaesthesiaAna Moreira, Susana Cadinha, Patrícia Barreira, Ana Castro Neves, Daniela Malheiro, Sara Correia, J. P. Moreira Da SilvaP167 IL-10 can be related to successful desensitizationAsli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin Çatin-Aktas, Gunnur DenizP168 Immediate reactions to proton pump inhibitors: value of basophil activation testMaria Salas, Jose Julio Laguna, Esther Barrionuevo, J. Dionicio, Tahia Fernandez, R. Gonzalez-Mendiola, I. Olazabal, Maria Dolores Ruiz, Miguel Blanca, Cristobalina Mayorga, Maria José TorresP169 Improvement of the elevated tryptase criterion to discriminate IgE from non-IgE mediated allergic reactionsGabriel Gastaminza, Alberto Lafuente, Carmen D’Amelio, Amalia Bernad, Olga Vega, Roselle Catherine Madamba, M. Jose Goikoetxea, Marta Ferrer, Jorge NúñezP170 Low expression of Tim-3 could serve as a biomarker for control and diagnose maculopapular exanthema induced by drugsTahia Diana Fernández, Inmaculada Doña, Francisca Palomares, Rubén Fernández, Maria Salas, Esther Barrionuevo, Maria Isabel Sanchez, Miguel Blanca, Maria José Torres, Cristobalina MayorgaP171 Role of basophil activation test using two different activation markers for the diagnosis of allergy to fluoroquinolonesEsther Barrionuevo, Tahía Fernandez, Arturo Ruiz, Adriana Ariza, Maria Salas, Inmaculada Doña, Ana Molina, Miguel Blanca, Maria Jose Torres, Cristobalina MayorgaP172 The importance of basophil activation test in anaphylaxis due to celecoxibAmalia Bernad Alonso, Carmen D’Amelio Garófalo, Olga Vega Matute, Marta Ferrer Puga, María José Goikoetxea Lapresa, Roselle Catherine Yu Madamba, Gabriel Gastaminza LasarteP173 The role of basophil activation test in the diagnosis of immediate type drug hypersensitivity to betalactam antibioticsAntonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina BalakirskiPoster walk 20: TCR recognition, cellular (P174–P183)P174 Characterisation of the effect of co-inhibitory signalling on the activation of drug-derived antigen-specific T-cellsAndrew Gibson, Monday Ogese, Lee Faulkner, B. Kevin Park, Dean J. NaisbittP175 Characterization of drug hapten-specific T cell responses in piperacillin hypersensitive patientsZaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, Paul Whitaker, Daniel Peckham, Lee Faulkner, John Farrel, Kevin Park, Dean NaisbittP176 Characterization of the response of T-cells to telaprevir and its metabolite in normal volunteersZaid Al-Attar, Khetam Alhilali, Yanni Xue, John Farrell, Lee Faulkner, Kevin Park, Dean NaisbittP177 Characterization of the T cell receptor signatures of drug-responsive T cellsPatricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony PurcellP178 Defining the signals between hepatocytes and immune cells in idiosyncratic drug-induced liver injury (DILI)Monday O. Ogese, Lee Faulkner, B. Kevin Park, Catherine Betts, Dean J. NaisbittP179 Development of novel chemicals that do not bind to HLA-B*57:01 or activate CD8 + T-cells through modification of the 6-amino cyclopropyl group of abacavirPaul Thomson, John Farrell, Mohammad Alhaidari, Neill Berry, Paul M. O’Neill, B. Kevin Park, Dean J. NaisbittP180 Generation and characterization of dapsone- and nitroso-dapsone-specific T-cell clones using lymphocytes from healthy volunteersAbdulaziz Alzahrani, Monday O. Ogese, John Farrell, Lee Faulkner, Andrew Gibson, Arun Tailor, B. Kevin Park, Dean J. NaisbittP181 Identification of benzylpenicillin-hapten peptides responsible for naïve T-cell activation and immunization of allergic patients to penicillinMarie Eliane Azoury, Lucia Fili, Rami Bechara, Noémie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc PallardyP182 Massive expansion of clonotypic and polycytotoxic CD8+ T cells in toxic epidermal necrolysisAxel Patrice Villani, Aurore Rozières, Benoît Bensaïd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Marc Pallardy, Janet Maryanski, Jean-François Nicolas, Osami Kanagawa, Marc VocansonP183 Pharmaco-immunological synapse of HLA-drug-TCR in SCARShuen-Iu HungPoster walk 21: new in vitro methods, haptens, etc. (P184–P194)P184 Amoxicillin-clavulanate forms distinct multiple haptenic structures on human serum albumin in patientsXiaoli Meng, Arun Tailor, Caroline J. Harrison, Rosalind E. Jenkins, Paul Whitaker, Neil S. French, Dean J. Naisbitt, B. Kevin ParkP185 Dendrimeric antigens for studying the influence of penicillin determinants orientation on IgE recognitionMaria Isabel Montañez, Cristobalina Mayorga, Francisco Najera, Adriana Ariza, Tahia D. Fernandez, Maria Salas, Angela Martin-Serrano, Miguel Blanca, Ezequiel Perez-Inestrosa, Maria Jose TorresP186 Dendrimeric antigens on solid supports: designed materials for IgE quantificationYolanda Vida, Maria Isabel Montañez, Noemi Molina, Daniel Collado, Francisco Najera, Adriana Ariza, Maria Jose Torres, Cristobalina Mayorga, Ezequiel Perez-InestrosaP187 Development of a screening assay for drug hypersensitivity using naïve T cells from donors with seven different HLA class I risk allelesLee Faulkner, Sally Wood, Ana Alfirevic, Munir Pirmohamed, Dean J. Naisbitt, B. Kevin ParkP188 Different patterns of recognition of structures derived from amoxicillin by IgE antibodies from patients with immediate hypersensitivity reactions to betalactamsAdriana Ariza, Cristobalina Mayorga, María Isabel Montañez, María Salas, Inmaculada Doña, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Miguel Blanca, Antonio E. Guzmán, María José TorresP189 High-resolution typing of HLA polymorphism and T-cell receptor repertoire for severe adverse drug reactions based on the cost-effective next-generation sequencing approachesTai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn WuP190 Identification and fate of intracellular proteins haptenated by amoxicillinFrancisco J. Sánchez-Gómez, Juan M. González-Morena, Yolanda Vida, Ezequiel Pérez-Inestrosa, Miguel Blanca, María J. Torres, Dolores Pérez-SalaP191 In vitro detection of terbinafine protein adductsArun Tailor, Toru Usui, Yanni Xue, Xiaoli Meng, Dean J. Naisbitt, B. Kevin ParkP192 MicroRNAs dysregulation in PBMCs from drug hypersensitivity patients during drug challenge in vitroAlejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Dean J. Naisbitt, Noe Valentin Duran Figueroa, Jose Luis Castrejon FloresP193 NSAIDs-exacerbated cutaneous disease: high throughput gene expression profilingJosé Antonio Cornejo-García, James Perkins, Natalia Blanca-López, Diana Pérez-Alzate, Raquel Jurado-Escobar, Inmaculada Doña, Gador Bogas, María J. Torres, Gabriela Canto, Miguel BlancaP194 Utility of skin tests in non-immediate reactions to amoxicillinLuis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiago
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