Communication between mitochondria and other organelles: a brand-new perspective on mitochondria in cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

MengFang Xia, YaZhuo Zhang, Ke Jin, ZiTong Lu, Zhaoyang Zeng, Wei Xiong

ABSTRACT

Mitochondria are energy factories of cells and are important pivots for intracellular interactions with other organelles. They interact with the endoplasmic reticulum, peroxisomes, and nucleus through signal transduction, vesicle transport, and membrane contact sites to regulate energy metabolism, biosynthesis, immune response, and cell turnover. However, when the communication between organelles fails and the mitochondria are dysfunctional, it may induce tumorigenesis. In this review, we elaborate on how mitochondria interact with the endoplasmic reticulum, peroxisomes, and cell nuclei, as well as the relation between organelle communication and tumor development . More... »

PAGES

27

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13578-019-0289-8

    DOI

    http://dx.doi.org/10.1186/s13578-019-0289-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112876428

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30931098


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