Phenotype annotation with the ontology of microbial phenotypes (OMP) View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-07-15

AUTHORS

Deborah A. Siegele, Sandra A. LaBonte, Peter I-Fan Wu, Marcus C. Chibucos, Suvarna Nandendla, Michelle G. Giglio, James C. Hu

ABSTRACT

BackgroundMicrobial genetics has formed a foundation for understanding many aspects of biology. Systematic annotation that supports computational data mining should reveal further insights for microbes, microbiomes, and conserved functions beyond microbes. The Ontology of Microbial Phenotypes (OMP) was created to support such annotation.ResultsWe define standards for an OMP-based annotation framework that supports the capture of a variety of phenotypes and provides flexibility for different levels of detail based on a combination of pre- and post-composition using OMP and other Open Biomedical Ontology (OBO) projects. A system for entering and viewing OMP annotations has been added to our online, public, web-based data portal.ConclusionsThe annotation framework described here is ready to support projects to capture phenotypes from the experimental literature for a variety of microbes. Defining the OMP annotation standard should support the development of new software tools for data mining and analysis in comparative phenomics. More... »

PAGES

13

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13326-019-0205-5

DOI

http://dx.doi.org/10.1186/s13326-019-0205-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1118014132

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/31307550


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