Multimodality imaging of indolent B cell lymphoma from diagnosis to transformation: what every radiologist should know View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-12

AUTHORS

Francesco Alessandrino, Pamela J. DiPiro, Jyothi P. Jagannathan, Gosangi Babina, Katherine M. Krajewski, Nikhil H. Ramaiya, Angela A. Giardino

ABSTRACT

Indolent B cell lymphomas are a group of lymphoid malignancies characterized by their potential to undergo histologic transformation to aggressive lymphomas. While different subtypes of indolent B cell lymphomas demonstrate specific clinical and imaging features, histologic transformation can be suspected on cross-sectional imaging when disproportionate lymph node enlargement or new focal lesions in extranodal organs are seen. On PET/CT, transformed indolent lymphoma may show new or increased nodal FDG avidity or new FDG-avid lesions in different organs. In this article, we will (1) review the imaging features of different subtypes of indolent B cell lymphomas, (2) discuss the imaging features of histologic transformation, and (3) propose a diagnostic algorithm for transformed indolent lymphoma. The purpose of this review is to familiarize radiologists with the spectrum of clinical and imaging features of indolent B cell lymphomas and to define the role of imaging in raising concern for transformation and in guiding biopsy for confirmation. More... »

PAGES

25

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13244-019-0705-y

DOI

http://dx.doi.org/10.1186/s13244-019-0705-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112315671

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30796644


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