Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-11-13

AUTHORS

Anouck Amestoy, Etienne Guillaud, Giulia Bucchioni, Tiziana Zalla, Daniel Umbricht, Christopher Chatham, Lorraine Murtagh, Josselin Houenou, Richard Delorme, Myriam Ly-Le Moal, Marion Leboyer, Manuel Bouvard, Jean-René Cazalets

ABSTRACT

BackgroundInhibitory control and attention processing atypicalities are implicated in various diseases, including autism spectrum disorders (ASD). These cognitive functions can be tested by using visually guided saccade-based paradigms in children, adolescents and adults to determine the time course of such disorders.MethodsIn this study, using Gap, Step, Overlap and Antisaccade tasks, we analyzed the oculomotor behavior of 82 children, teenagers and adults with high functioning ASD and their peer typically developing (TD) controls in a two-year follow-up study under the auspices of the InFoR-Autism project. Analysis of correlations between oculomotors task measurements and diagnostic assessment of attentional (ADHD-RS and ADHD comorbidity indices) and executive functioning (BRIEF scales) were conducted in order to evaluate their relationship with the oculomotor performance of participants with ASD.ResultsAs indicated by the presence of a Gap and Overlap effects in all age groups, the oculomotor performances of ASD participants showed a preserved capability in overt attention switching. In contrast, the difference in performances of ASD participants in the Antisaccade task, compared to their TD peers, indicated an atypical development of inhibition and executive functions. From correlation analysis between our oculomotor data and ADHD comorbidity index, and scores of attention and executive function difficulties, our findings support the hypothesis that a specific dysfunction of inhibition skills occurs in ASD participants that is independent of the presence of ADHD comorbidity.LimitationsThese include the relatively small sample size of the ASD group over the study’s two-year period, the absence of an ADHD-only control group and the evaluation of a TD control group solely at the study’s inception.ConclusionsChildren and teenagers with ASD have greater difficulty in attention switching and inhibiting prepotent stimuli. Adults with ASD can overcome these difficulties, but, similar to teenagers and children with ASD, they make more erroneous and anticipatory saccades and display a greater trial-to-trial variability in all oculomotor tasks compared to their peers. Our results are indicative of a developmental delay in the maturation of executive and attentional functioning in ASD and of a specific impairment in inhibitory control. More... »

PAGES

71

References to SciGraph publications

  • 2015-08-23. Enhancing Children’s Social Emotional Functioning Through Virtual Game-Based Delivery of Social Skills Training in JOURNAL OF CHILD AND FAMILY STUDIES
  • 2000-06. The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2004-03. Look away: the anti-saccade task and the voluntary control of eye movement in NATURE REVIEWS NEUROSCIENCE
  • 2012-10-09. The Specificity of Inhibitory Impairments in Autism and Their Relation to ADHD-Type Symptoms in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2010-08-17. Atypical Disengagement from Faces and Its Modulation by the Control of Eye Fixation in Children with Autism Spectrum Disorder in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 1984-07. Latency of visually evoked saccadic eye movements in BIOLOGICAL CYBERNETICS
  • 1991-03. The reduction of saccadic latency by prior offset of the fixation point: An analysis of the gap effect in ATTENTION, PERCEPTION, & PSYCHOPHYSICS
  • 1984-07. Latency of visually evoked saccadic eye movements in BIOLOGICAL CYBERNETICS
  • 2017-09-07. The disengagement of visual attention in the gap paradigm across adolescence in EXPERIMENTAL BRAIN RESEARCH
  • 2014-09-16. Saccadic eye movement abnormalities in autism spectrum disorder indicate dysfunctions in cerebellum and brainstem in MOLECULAR AUTISM
  • 1998-08. Age-related performance of human subjects on saccadic eye movement tasks in EXPERIMENTAL BRAIN RESEARCH
  • 2006-11-21. Eye Movement and Visual Search: Are There Elementary Abnormalities in Autism? in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2010-03-02. Motor Coordination in Autism Spectrum Disorders: A Synthesis and Meta-Analysis in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2010-01-27. Sensory Responsiveness as a Predictor of Social Severity in Children with High Functioning Autism Spectrum Disorders in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2016-01-27. Eye Tracking Reveals Impaired Attentional Disengagement Associated with Sensory Response Patterns in Children with Autism in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2012-07-27. Saccadic eye movements in children: a developmental study in EXPERIMENTAL BRAIN RESEARCH
  • 2013-11-06. Attention to eyes is present but in decline in 2–6-month-old infants later diagnosed with autism in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13229-021-00474-2

    DOI

    http://dx.doi.org/10.1186/s13229-021-00474-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1142565225

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34774105


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Attention Deficit Disorder with Hyperactivity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Autism Spectrum Disorder", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Autistic Disorder", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Eye Movements", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Follow-Up Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Intellectual Disability", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "centre hospitalier Charles-Perrens, P\u00f4le universitaire de psychiatrie de l\u2019enfant et de l\u2019adolescent, 121, rue de la B\u00e9chade, CS 81285, 33076, Bordeaux Cedex, France", 
              "id": "http://www.grid.ac/institutes/grid.489895.1", 
              "name": [
                "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France", 
                "Fondation FondaMental, Cr\u00e9teil, France", 
                "centre hospitalier Charles-Perrens, P\u00f4le universitaire de psychiatrie de l\u2019enfant et de l\u2019adolescent, 121, rue de la B\u00e9chade, CS 81285, 33076, Bordeaux Cedex, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Amestoy", 
            "givenName": "Anouck", 
            "id": "sg:person.0777450667.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777450667.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France", 
              "id": "http://www.grid.ac/institutes/grid.462004.4", 
              "name": [
                "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Guillaud", 
            "givenName": "Etienne", 
            "id": "sg:person.01123561567.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123561567.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "iBrain, UMR 1253 Inserm, Universit\u00e9 de Tours, 2 Boulevard Tonnell\u00e9, 37044, Tours Cedex, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France", 
                "iBrain, UMR 1253 Inserm, Universit\u00e9 de Tours, 2 Boulevard Tonnell\u00e9, 37044, Tours Cedex, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bucchioni", 
            "givenName": "Giulia", 
            "id": "sg:person.0607124621.03", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607124621.03"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institut Jean Nicod, ENS, Paris, France", 
              "id": "http://www.grid.ac/institutes/grid.483425.c", 
              "name": [
                "Institut Jean Nicod, ENS, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zalla", 
            "givenName": "Tiziana", 
            "id": "sg:person.0723614530.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723614530.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.417570.0", 
              "name": [
                "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Umbricht", 
            "givenName": "Daniel", 
            "id": "sg:person.01035356625.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035356625.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.417570.0", 
              "name": [
                "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chatham", 
            "givenName": "Christopher", 
            "id": "sg:person.01020664073.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020664073.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.417570.0", 
              "name": [
                "Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Murtagh", 
            "givenName": "Lorraine", 
            "id": "sg:person.015557474627.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015557474627.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "NeuroSpin, UNIACT Lab, Equipe de psychiatrie, Commissariat \u00e0 l\u2019\u00e9nergie atomique, Saclay, Gif-sur-Yvette, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Fondation FondaMental, Cr\u00e9teil, France", 
                "NeuroSpin, UNIACT Lab, Equipe de psychiatrie, Commissariat \u00e0 l\u2019\u00e9nergie atomique, Saclay, Gif-sur-Yvette, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Houenou", 
            "givenName": "Josselin", 
            "id": "sg:person.0610300456.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610300456.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Universit\u00e9 Paris Est Cr\u00e9teil, Cr\u00e9teil, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Fondation FondaMental, Cr\u00e9teil, France", 
                "Institut Pasteur, Paris, France", 
                "AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Universit\u00e9 Paris Est Cr\u00e9teil, Cr\u00e9teil, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Delorme", 
            "givenName": "Richard", 
            "id": "sg:person.0667140354.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667140354.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institut Roche, Tour horizons- Bureau 18M3, Roche S.A.S., 30, cours de l\u2019\u00eele Seguin, 92650, Boulogne-Billancourt, France", 
              "id": "http://www.grid.ac/institutes/grid.438806.1", 
              "name": [
                "Institut Roche, Tour horizons- Bureau 18M3, Roche S.A.S., 30, cours de l\u2019\u00eele Seguin, 92650, Boulogne-Billancourt, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Moal", 
            "givenName": "Myriam Ly-Le", 
            "id": "sg:person.07540377046.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07540377046.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Universit\u00e9 Paris Est Cr\u00e9teil, Cr\u00e9teil, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Laboratoire de NeuroPsychiatrie translationnelle, INSERM, U955, IMRB, Cr\u00e9teil, France", 
                "Fondation FondaMental, Cr\u00e9teil, France", 
                "AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Universit\u00e9 Paris Est Cr\u00e9teil, Cr\u00e9teil, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Leboyer", 
            "givenName": "Marion", 
            "id": "sg:person.01020732460.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020732460.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "centre hospitalier Charles-Perrens, P\u00f4le universitaire de psychiatrie de l\u2019enfant et de l\u2019adolescent, 121, rue de la B\u00e9chade, CS 81285, 33076, Bordeaux Cedex, France", 
              "id": "http://www.grid.ac/institutes/grid.489895.1", 
              "name": [
                "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France", 
                "Fondation FondaMental, Cr\u00e9teil, France", 
                "centre hospitalier Charles-Perrens, P\u00f4le universitaire de psychiatrie de l\u2019enfant et de l\u2019adolescent, 121, rue de la B\u00e9chade, CS 81285, 33076, Bordeaux Cedex, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bouvard", 
            "givenName": "Manuel", 
            "id": "sg:person.0723634563.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723634563.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France", 
              "id": "http://www.grid.ac/institutes/grid.462004.4", 
              "name": [
                "CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Universit\u00e9 de Bordeaux, 33000, Bordeaux, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cazalets", 
            "givenName": "Jean-Ren\u00e9", 
            "id": "sg:person.01140675337.79", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140675337.79"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00221-017-5085-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091503506", 
              "https://doi.org/10.1007/s00221-017-5085-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-010-0981-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028871239", 
              "https://doi.org/10.1007/s10803-010-0981-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-006-0277-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034014309", 
              "https://doi.org/10.1007/s10803-006-0277-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrn1345", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037909996", 
              "https://doi.org/10.1038/nrn1345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10826-015-0274-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004497586", 
              "https://doi.org/10.1007/s10826-015-0274-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00221-012-3192-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029559298", 
              "https://doi.org/10.1007/s00221-012-3192-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.3758/bf03205036", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016252685", 
              "https://doi.org/10.3758/bf03205036"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00337076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008996734", 
              "https://doi.org/10.1007/bf00337076"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-010-1082-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018051894", 
              "https://doi.org/10.1007/s10803-010-1082-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-010-0944-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008796673", 
              "https://doi.org/10.1007/s10803-010-0944-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-015-2681-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044628133", 
              "https://doi.org/10.1007/s10803-015-2681-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/2040-2392-5-47", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010632493", 
              "https://doi.org/10.1186/2040-2392-5-47"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12715", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007445842", 
              "https://doi.org/10.1038/nature12715"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00337075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043408347", 
              "https://doi.org/10.1007/bf00337075"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1005592401947", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036427450", 
              "https://doi.org/10.1023/a:1005592401947"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s002210050473", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049851503", 
              "https://doi.org/10.1007/s002210050473"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10803-012-1650-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051254468", 
              "https://doi.org/10.1007/s10803-012-1650-5"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2021-11-13", 
        "datePublishedReg": "2021-11-13", 
        "description": "BackgroundInhibitory control and attention processing atypicalities are implicated in various diseases, including autism spectrum disorders (ASD). These cognitive functions can be tested by using visually guided saccade-based paradigms in children, adolescents and adults to determine the time course of such disorders.MethodsIn this study, using Gap, Step, Overlap and Antisaccade tasks, we analyzed the oculomotor behavior of 82 children, teenagers and adults with high functioning ASD and their peer typically developing (TD) controls in a two-year follow-up study under the auspices of the InFoR-Autism project. Analysis of correlations between oculomotors task measurements and diagnostic assessment of attentional (ADHD-RS and ADHD comorbidity indices) and executive functioning (BRIEF scales) were conducted in order to evaluate their relationship with the oculomotor performance of participants with ASD.ResultsAs indicated by the presence of a Gap and Overlap effects in all age groups, the oculomotor performances of ASD participants showed a preserved capability in overt attention switching. In contrast, the difference in performances of ASD participants in the Antisaccade task, compared to their TD peers, indicated an atypical development of inhibition and executive functions. From correlation analysis between our oculomotor data and ADHD comorbidity index, and scores of attention and executive function difficulties, our findings support the hypothesis that a specific dysfunction of inhibition skills occurs in ASD participants that is independent of the presence of ADHD comorbidity.LimitationsThese include the relatively small sample size of the ASD group over the study\u2019s two-year period, the absence of an ADHD-only control group and the evaluation of a TD control group solely at the study\u2019s inception.ConclusionsChildren and teenagers with ASD have greater difficulty in attention switching and inhibiting prepotent stimuli. Adults with ASD can overcome these difficulties, but, similar to teenagers and children with ASD, they make more erroneous and anticipatory saccades and display a greater trial-to-trial variability in all oculomotor tasks compared to their peers. Our results are indicative of a developmental delay in the maturation of executive and attentional functioning in ASD and of a specific impairment in inhibitory control.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/s13229-021-00474-2", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1043709", 
            "issn": [
              "2040-2392"
            ], 
            "name": "Molecular Autism", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "12"
          }
        ], 
        "keywords": [
          "autism spectrum disorder", 
          "ASD participants", 
          "inhibitory control", 
          "antisaccade task", 
          "oculomotor tasks", 
          "oculomotor performance", 
          "executive function difficulties", 
          "TD control group", 
          "scores of attention", 
          "attentional functioning", 
          "executive functioning", 
          "inhibition skills", 
          "attention switching", 
          "TD peers", 
          "visual attention", 
          "ASD group", 
          "prepotent stimulus", 
          "atypical development", 
          "executive function", 
          "spectrum disorder", 
          "specific impairment", 
          "ADHD comorbidity", 
          "oculomotor behavior", 
          "cognitive function", 
          "greater trial", 
          "task measurements", 
          "oculomotor data", 
          "anticipatory saccades", 
          "trial variability", 
          "specific dysfunction", 
          "intellectual disability", 
          "task", 
          "peers", 
          "participants", 
          "great difficulty", 
          "functioning", 
          "developmental delay", 
          "children", 
          "diagnostic assessment", 
          "teenagers", 
          "adults", 
          "longitudinal follow", 
          "such disorders", 
          "control group", 
          "attention", 
          "small sample size", 
          "difficulties", 
          "two-year follow", 
          "ADHD", 
          "atypicality", 
          "autism", 
          "disorders", 
          "age groups", 
          "adolescents", 
          "time course", 
          "study inception", 
          "stimuli", 
          "saccades", 
          "skills", 
          "analysis of correlation", 
          "overlap effects", 
          "correlation analysis", 
          "impairment", 
          "paradigm", 
          "performance", 
          "disability", 
          "two-year period", 
          "sample size", 
          "ConclusionsChildren", 
          "scores", 
          "findings", 
          "group", 
          "hypothesis", 
          "relationship", 
          "study", 
          "behavior", 
          "control", 
          "overlap", 
          "differences", 
          "assessment", 
          "gap", 
          "results", 
          "trials", 
          "follow", 
          "comorbidities", 
          "course", 
          "dysfunction", 
          "ResultsA", 
          "delay", 
          "function", 
          "development", 
          "effect", 
          "analysis", 
          "variability", 
          "contrast", 
          "correlation", 
          "evaluation", 
          "switching", 
          "data", 
          "inception", 
          "MethodsIn", 
          "project", 
          "maturation", 
          "index", 
          "order", 
          "capability", 
          "absence", 
          "period", 
          "inhibition", 
          "step", 
          "auspices", 
          "presence", 
          "size", 
          "measurements", 
          "disease", 
          "comorbidity index"
        ], 
        "name": "Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from a 2-year longitudinal follow-up study (InFoR)", 
        "pagination": "71", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1142565225"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s13229-021-00474-2"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "34774105"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s13229-021-00474-2", 
          "https://app.dimensions.ai/details/publication/pub.1142565225"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-05-20T07:37", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_881.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/s13229-021-00474-2"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13229-021-00474-2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13229-021-00474-2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13229-021-00474-2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13229-021-00474-2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    394 TRIPLES      22 PREDICATES      169 URIs      144 LITERALS      17 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s13229-021-00474-2 schema:about N057a8c9b99f347f2bbada72d57406408
    2 N1bd7e069ba2f4962b73a68ba79bd6f7d
    3 N2c9a934e353743beaa9fb832a018311a
    4 N5348b7797e084e40b253c16d0ff9e770
    5 N789aa6c599704152a03e0012348f339d
    6 N995174a4d3c64714a41dc50465d942f4
    7 N997853036d2a415380a77fc0a2d39e69
    8 Na9b1c21839584924aacb981326ef5823
    9 Ncea1460c157d4c6984b2ab1c5d596d41
    10 Nec669a7fd20e486b81ba81b5002ea997
    11 anzsrc-for:11
    12 anzsrc-for:1103
    13 schema:author Ned5c51dd465d41e2bc6eed063d51138b
    14 schema:citation sg:pub.10.1007/bf00337075
    15 sg:pub.10.1007/bf00337076
    16 sg:pub.10.1007/s00221-012-3192-7
    17 sg:pub.10.1007/s00221-017-5085-2
    18 sg:pub.10.1007/s002210050473
    19 sg:pub.10.1007/s10803-006-0277-9
    20 sg:pub.10.1007/s10803-010-0944-8
    21 sg:pub.10.1007/s10803-010-0981-3
    22 sg:pub.10.1007/s10803-010-1082-z
    23 sg:pub.10.1007/s10803-012-1650-5
    24 sg:pub.10.1007/s10803-015-2681-5
    25 sg:pub.10.1007/s10826-015-0274-8
    26 sg:pub.10.1023/a:1005592401947
    27 sg:pub.10.1038/nature12715
    28 sg:pub.10.1038/nrn1345
    29 sg:pub.10.1186/2040-2392-5-47
    30 sg:pub.10.3758/bf03205036
    31 schema:datePublished 2021-11-13
    32 schema:datePublishedReg 2021-11-13
    33 schema:description BackgroundInhibitory control and attention processing atypicalities are implicated in various diseases, including autism spectrum disorders (ASD). These cognitive functions can be tested by using visually guided saccade-based paradigms in children, adolescents and adults to determine the time course of such disorders.MethodsIn this study, using Gap, Step, Overlap and Antisaccade tasks, we analyzed the oculomotor behavior of 82 children, teenagers and adults with high functioning ASD and their peer typically developing (TD) controls in a two-year follow-up study under the auspices of the InFoR-Autism project. Analysis of correlations between oculomotors task measurements and diagnostic assessment of attentional (ADHD-RS and ADHD comorbidity indices) and executive functioning (BRIEF scales) were conducted in order to evaluate their relationship with the oculomotor performance of participants with ASD.ResultsAs indicated by the presence of a Gap and Overlap effects in all age groups, the oculomotor performances of ASD participants showed a preserved capability in overt attention switching. In contrast, the difference in performances of ASD participants in the Antisaccade task, compared to their TD peers, indicated an atypical development of inhibition and executive functions. From correlation analysis between our oculomotor data and ADHD comorbidity index, and scores of attention and executive function difficulties, our findings support the hypothesis that a specific dysfunction of inhibition skills occurs in ASD participants that is independent of the presence of ADHD comorbidity.LimitationsThese include the relatively small sample size of the ASD group over the study’s two-year period, the absence of an ADHD-only control group and the evaluation of a TD control group solely at the study’s inception.ConclusionsChildren and teenagers with ASD have greater difficulty in attention switching and inhibiting prepotent stimuli. Adults with ASD can overcome these difficulties, but, similar to teenagers and children with ASD, they make more erroneous and anticipatory saccades and display a greater trial-to-trial variability in all oculomotor tasks compared to their peers. Our results are indicative of a developmental delay in the maturation of executive and attentional functioning in ASD and of a specific impairment in inhibitory control.
    34 schema:genre article
    35 schema:inLanguage en
    36 schema:isAccessibleForFree true
    37 schema:isPartOf N97167f56d573442a9d78731f918ac623
    38 Nf78b2d3e00bd4e65b203abc9bb8c7330
    39 sg:journal.1043709
    40 schema:keywords ADHD
    41 ADHD comorbidity
    42 ASD group
    43 ASD participants
    44 ConclusionsChildren
    45 MethodsIn
    46 ResultsA
    47 TD control group
    48 TD peers
    49 absence
    50 adolescents
    51 adults
    52 age groups
    53 analysis
    54 analysis of correlation
    55 anticipatory saccades
    56 antisaccade task
    57 assessment
    58 attention
    59 attention switching
    60 attentional functioning
    61 atypical development
    62 atypicality
    63 auspices
    64 autism
    65 autism spectrum disorder
    66 behavior
    67 capability
    68 children
    69 cognitive function
    70 comorbidities
    71 comorbidity index
    72 contrast
    73 control
    74 control group
    75 correlation
    76 correlation analysis
    77 course
    78 data
    79 delay
    80 development
    81 developmental delay
    82 diagnostic assessment
    83 differences
    84 difficulties
    85 disability
    86 disease
    87 disorders
    88 dysfunction
    89 effect
    90 evaluation
    91 executive function
    92 executive function difficulties
    93 executive functioning
    94 findings
    95 follow
    96 function
    97 functioning
    98 gap
    99 great difficulty
    100 greater trial
    101 group
    102 hypothesis
    103 impairment
    104 inception
    105 index
    106 inhibition
    107 inhibition skills
    108 inhibitory control
    109 intellectual disability
    110 longitudinal follow
    111 maturation
    112 measurements
    113 oculomotor behavior
    114 oculomotor data
    115 oculomotor performance
    116 oculomotor tasks
    117 order
    118 overlap
    119 overlap effects
    120 paradigm
    121 participants
    122 peers
    123 performance
    124 period
    125 prepotent stimulus
    126 presence
    127 project
    128 relationship
    129 results
    130 saccades
    131 sample size
    132 scores
    133 scores of attention
    134 size
    135 skills
    136 small sample size
    137 specific dysfunction
    138 specific impairment
    139 spectrum disorder
    140 step
    141 stimuli
    142 study
    143 study inception
    144 such disorders
    145 switching
    146 task
    147 task measurements
    148 teenagers
    149 time course
    150 trial variability
    151 trials
    152 two-year follow
    153 two-year period
    154 variability
    155 visual attention
    156 schema:name Visual attention and inhibitory control in children, teenagers and adults with autism without intellectual disability: results of oculomotor tasks from a 2-year longitudinal follow-up study (InFoR)
    157 schema:pagination 71
    158 schema:productId N30dab0f30548415d927ab4608daa104a
    159 N82d0443c83fe43459e80c44bc027af7d
    160 Ncbfb099f6915458e999ab87a5611b391
    161 schema:sameAs https://app.dimensions.ai/details/publication/pub.1142565225
    162 https://doi.org/10.1186/s13229-021-00474-2
    163 schema:sdDatePublished 2022-05-20T07:37
    164 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    165 schema:sdPublisher N3c0b1393c33d4408bdebfc43c0cec749
    166 schema:url https://doi.org/10.1186/s13229-021-00474-2
    167 sgo:license sg:explorer/license/
    168 sgo:sdDataset articles
    169 rdf:type schema:ScholarlyArticle
    170 N057a8c9b99f347f2bbada72d57406408 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Autistic Disorder
    172 rdf:type schema:DefinedTerm
    173 N0b5e9002274345dc9a0e4b17a777d225 rdf:first sg:person.0667140354.02
    174 rdf:rest N94c365471a8848dca27aa821983643ed
    175 N1bd7e069ba2f4962b73a68ba79bd6f7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    176 schema:name Eye Movements
    177 rdf:type schema:DefinedTerm
    178 N20dabe5608ab43a8bf58eaf6b67c9079 rdf:first sg:person.015557474627.47
    179 rdf:rest Nc62f0d8f5c4f4480b9499effef6acf0d
    180 N2c9a934e353743beaa9fb832a018311a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Child
    182 rdf:type schema:DefinedTerm
    183 N30dab0f30548415d927ab4608daa104a schema:name dimensions_id
    184 schema:value pub.1142565225
    185 rdf:type schema:PropertyValue
    186 N3c0b1393c33d4408bdebfc43c0cec749 schema:name Springer Nature - SN SciGraph project
    187 rdf:type schema:Organization
    188 N3ed1b15fa42442ba9288f90851ec1b9d rdf:first sg:person.0607124621.03
    189 rdf:rest N6aa598a702cf4c6896f8bf88c6224b0a
    190 N4290b2733c1d4fba9a233c90c2155aae rdf:first sg:person.01140675337.79
    191 rdf:rest rdf:nil
    192 N444dd8aee8df4f739546207892c282df rdf:first sg:person.01020664073.94
    193 rdf:rest N20dabe5608ab43a8bf58eaf6b67c9079
    194 N5348b7797e084e40b253c16d0ff9e770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Intellectual Disability
    196 rdf:type schema:DefinedTerm
    197 N6aa598a702cf4c6896f8bf88c6224b0a rdf:first sg:person.0723614530.96
    198 rdf:rest N6f101476cb8947cbbdee720581fea04a
    199 N6f101476cb8947cbbdee720581fea04a rdf:first sg:person.01035356625.53
    200 rdf:rest N444dd8aee8df4f739546207892c282df
    201 N789aa6c599704152a03e0012348f339d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    202 schema:name Follow-Up Studies
    203 rdf:type schema:DefinedTerm
    204 N82d0443c83fe43459e80c44bc027af7d schema:name pubmed_id
    205 schema:value 34774105
    206 rdf:type schema:PropertyValue
    207 N94c365471a8848dca27aa821983643ed rdf:first sg:person.07540377046.26
    208 rdf:rest N9f3876a8bcef455ebffda6c9d7bbb044
    209 N97167f56d573442a9d78731f918ac623 schema:volumeNumber 12
    210 rdf:type schema:PublicationVolume
    211 N995174a4d3c64714a41dc50465d942f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    212 schema:name Autism Spectrum Disorder
    213 rdf:type schema:DefinedTerm
    214 N997853036d2a415380a77fc0a2d39e69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    215 schema:name Adult
    216 rdf:type schema:DefinedTerm
    217 N9f3876a8bcef455ebffda6c9d7bbb044 rdf:first sg:person.01020732460.64
    218 rdf:rest Ne1765a1a0b7148b395fa11343178af5d
    219 Na9b1c21839584924aacb981326ef5823 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    220 schema:name Humans
    221 rdf:type schema:DefinedTerm
    222 Nb2225203c7eb4791b7dafdafb31e4c63 rdf:first sg:person.01123561567.42
    223 rdf:rest N3ed1b15fa42442ba9288f90851ec1b9d
    224 Nc62f0d8f5c4f4480b9499effef6acf0d rdf:first sg:person.0610300456.41
    225 rdf:rest N0b5e9002274345dc9a0e4b17a777d225
    226 Ncbfb099f6915458e999ab87a5611b391 schema:name doi
    227 schema:value 10.1186/s13229-021-00474-2
    228 rdf:type schema:PropertyValue
    229 Ncea1460c157d4c6984b2ab1c5d596d41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    230 schema:name Attention Deficit Disorder with Hyperactivity
    231 rdf:type schema:DefinedTerm
    232 Ne1765a1a0b7148b395fa11343178af5d rdf:first sg:person.0723634563.94
    233 rdf:rest N4290b2733c1d4fba9a233c90c2155aae
    234 Nec669a7fd20e486b81ba81b5002ea997 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    235 schema:name Adolescent
    236 rdf:type schema:DefinedTerm
    237 Ned5c51dd465d41e2bc6eed063d51138b rdf:first sg:person.0777450667.85
    238 rdf:rest Nb2225203c7eb4791b7dafdafb31e4c63
    239 Nf78b2d3e00bd4e65b203abc9bb8c7330 schema:issueNumber 1
    240 rdf:type schema:PublicationIssue
    241 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    242 schema:name Medical and Health Sciences
    243 rdf:type schema:DefinedTerm
    244 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    245 schema:name Clinical Sciences
    246 rdf:type schema:DefinedTerm
    247 sg:journal.1043709 schema:issn 2040-2392
    248 schema:name Molecular Autism
    249 schema:publisher Springer Nature
    250 rdf:type schema:Periodical
    251 sg:person.01020664073.94 schema:affiliation grid-institutes:grid.417570.0
    252 schema:familyName Chatham
    253 schema:givenName Christopher
    254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020664073.94
    255 rdf:type schema:Person
    256 sg:person.01020732460.64 schema:affiliation grid-institutes:None
    257 schema:familyName Leboyer
    258 schema:givenName Marion
    259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020732460.64
    260 rdf:type schema:Person
    261 sg:person.01035356625.53 schema:affiliation grid-institutes:grid.417570.0
    262 schema:familyName Umbricht
    263 schema:givenName Daniel
    264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035356625.53
    265 rdf:type schema:Person
    266 sg:person.01123561567.42 schema:affiliation grid-institutes:grid.462004.4
    267 schema:familyName Guillaud
    268 schema:givenName Etienne
    269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123561567.42
    270 rdf:type schema:Person
    271 sg:person.01140675337.79 schema:affiliation grid-institutes:grid.462004.4
    272 schema:familyName Cazalets
    273 schema:givenName Jean-René
    274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140675337.79
    275 rdf:type schema:Person
    276 sg:person.015557474627.47 schema:affiliation grid-institutes:grid.417570.0
    277 schema:familyName Murtagh
    278 schema:givenName Lorraine
    279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015557474627.47
    280 rdf:type schema:Person
    281 sg:person.0607124621.03 schema:affiliation grid-institutes:None
    282 schema:familyName Bucchioni
    283 schema:givenName Giulia
    284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607124621.03
    285 rdf:type schema:Person
    286 sg:person.0610300456.41 schema:affiliation grid-institutes:None
    287 schema:familyName Houenou
    288 schema:givenName Josselin
    289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610300456.41
    290 rdf:type schema:Person
    291 sg:person.0667140354.02 schema:affiliation grid-institutes:None
    292 schema:familyName Delorme
    293 schema:givenName Richard
    294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667140354.02
    295 rdf:type schema:Person
    296 sg:person.0723614530.96 schema:affiliation grid-institutes:grid.483425.c
    297 schema:familyName Zalla
    298 schema:givenName Tiziana
    299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723614530.96
    300 rdf:type schema:Person
    301 sg:person.0723634563.94 schema:affiliation grid-institutes:grid.489895.1
    302 schema:familyName Bouvard
    303 schema:givenName Manuel
    304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723634563.94
    305 rdf:type schema:Person
    306 sg:person.07540377046.26 schema:affiliation grid-institutes:grid.438806.1
    307 schema:familyName Moal
    308 schema:givenName Myriam Ly-Le
    309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07540377046.26
    310 rdf:type schema:Person
    311 sg:person.0777450667.85 schema:affiliation grid-institutes:grid.489895.1
    312 schema:familyName Amestoy
    313 schema:givenName Anouck
    314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777450667.85
    315 rdf:type schema:Person
    316 sg:pub.10.1007/bf00337075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043408347
    317 https://doi.org/10.1007/bf00337075
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1007/bf00337076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008996734
    320 https://doi.org/10.1007/bf00337076
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1007/s00221-012-3192-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029559298
    323 https://doi.org/10.1007/s00221-012-3192-7
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1007/s00221-017-5085-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091503506
    326 https://doi.org/10.1007/s00221-017-5085-2
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1007/s002210050473 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049851503
    329 https://doi.org/10.1007/s002210050473
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1007/s10803-006-0277-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034014309
    332 https://doi.org/10.1007/s10803-006-0277-9
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1007/s10803-010-0944-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008796673
    335 https://doi.org/10.1007/s10803-010-0944-8
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1007/s10803-010-0981-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028871239
    338 https://doi.org/10.1007/s10803-010-0981-3
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1007/s10803-010-1082-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1018051894
    341 https://doi.org/10.1007/s10803-010-1082-z
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1007/s10803-012-1650-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051254468
    344 https://doi.org/10.1007/s10803-012-1650-5
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1007/s10803-015-2681-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044628133
    347 https://doi.org/10.1007/s10803-015-2681-5
    348 rdf:type schema:CreativeWork
    349 sg:pub.10.1007/s10826-015-0274-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004497586
    350 https://doi.org/10.1007/s10826-015-0274-8
    351 rdf:type schema:CreativeWork
    352 sg:pub.10.1023/a:1005592401947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036427450
    353 https://doi.org/10.1023/a:1005592401947
    354 rdf:type schema:CreativeWork
    355 sg:pub.10.1038/nature12715 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007445842
    356 https://doi.org/10.1038/nature12715
    357 rdf:type schema:CreativeWork
    358 sg:pub.10.1038/nrn1345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037909996
    359 https://doi.org/10.1038/nrn1345
    360 rdf:type schema:CreativeWork
    361 sg:pub.10.1186/2040-2392-5-47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010632493
    362 https://doi.org/10.1186/2040-2392-5-47
    363 rdf:type schema:CreativeWork
    364 sg:pub.10.3758/bf03205036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016252685
    365 https://doi.org/10.3758/bf03205036
    366 rdf:type schema:CreativeWork
    367 grid-institutes:None schema:alternateName AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Université Paris Est Créteil, Créteil, France
    368 NeuroSpin, UNIACT Lab, Equipe de psychiatrie, Commissariat à l’énergie atomique, Saclay, Gif-sur-Yvette, France
    369 iBrain, UMR 1253 Inserm, Université de Tours, 2 Boulevard Tonnellé, 37044, Tours Cedex, France
    370 schema:name AP-HP, DMU IMPACT, Psychiatry and Addictology Department, Mondor University Hospital, Université Paris Est Créteil, Créteil, France
    371 CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Université de Bordeaux, 33000, Bordeaux, France
    372 Fondation FondaMental, Créteil, France
    373 Institut Pasteur, Paris, France
    374 Laboratoire de NeuroPsychiatrie translationnelle, INSERM, U955, IMRB, Créteil, France
    375 NeuroSpin, UNIACT Lab, Equipe de psychiatrie, Commissariat à l’énergie atomique, Saclay, Gif-sur-Yvette, France
    376 iBrain, UMR 1253 Inserm, Université de Tours, 2 Boulevard Tonnellé, 37044, Tours Cedex, France
    377 rdf:type schema:Organization
    378 grid-institutes:grid.417570.0 schema:alternateName Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland
    379 schema:name Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070, Basel, Switzerland
    380 rdf:type schema:Organization
    381 grid-institutes:grid.438806.1 schema:alternateName Institut Roche, Tour horizons- Bureau 18M3, Roche S.A.S., 30, cours de l’île Seguin, 92650, Boulogne-Billancourt, France
    382 schema:name Institut Roche, Tour horizons- Bureau 18M3, Roche S.A.S., 30, cours de l’île Seguin, 92650, Boulogne-Billancourt, France
    383 rdf:type schema:Organization
    384 grid-institutes:grid.462004.4 schema:alternateName CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Université de Bordeaux, 33000, Bordeaux, France
    385 schema:name CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Université de Bordeaux, 33000, Bordeaux, France
    386 rdf:type schema:Organization
    387 grid-institutes:grid.483425.c schema:alternateName Institut Jean Nicod, ENS, Paris, France
    388 schema:name Institut Jean Nicod, ENS, Paris, France
    389 rdf:type schema:Organization
    390 grid-institutes:grid.489895.1 schema:alternateName centre hospitalier Charles-Perrens, Pôle universitaire de psychiatrie de l’enfant et de l’adolescent, 121, rue de la Béchade, CS 81285, 33076, Bordeaux Cedex, France
    391 schema:name CNRS, Aquitaine Institute for Cognitive and Integrative Neuroscience, INCIA, UMR 5287, Université de Bordeaux, 33000, Bordeaux, France
    392 Fondation FondaMental, Créteil, France
    393 centre hospitalier Charles-Perrens, Pôle universitaire de psychiatrie de l’enfant et de l’adolescent, 121, rue de la Béchade, CS 81285, 33076, Bordeaux Cedex, France
    394 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...