The role and mechanisms of action of microRNAs in cancer drug resistance View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Wengong Si, Jiaying Shen, Huilin Zheng, Weimin Fan

ABSTRACT

MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19-25 nt, which can regulate various target genes and are thus involved in the regulation of a variety of biological and pathological processes, including the formation and development of cancer. Drug resistance in cancer chemotherapy is one of the main obstacles to curing this malignant disease. Statistical data indicate that over 90% of the mortality of patients with cancer is related to drug resistance. Drug resistance of cancer chemotherapy can be caused by many mechanisms, such as decreased antitumor drug uptake, modified drug targets, altered cell cycle checkpoints, or increased DNA damage repair, among others. In recent years, many studies have shown that miRNAs are involved in the drug resistance of tumor cells by targeting drug-resistance-related genes or influencing genes related to cell proliferation, cell cycle, and apoptosis. A single miRNA often targets a number of genes, and its regulatory effect is tissue-specific. In this review, we emphasize the miRNAs that are involved in the regulation of drug resistance among different cancers and probe the mechanisms of the deregulated expression of miRNAs. The molecular targets of miRNAs and their underlying signaling pathways are also explored comprehensively. A holistic understanding of the functions of miRNAs in drug resistance will help us develop better strategies to regulate them efficiently and will finally pave the way toward better translation of miRNAs into clinics, developing them into a promising approach in cancer therapy. More... »

PAGES

25

References to SciGraph publications

  • 2014-04. MicroRNAs: master regulators of drug resistance, stemness, and metastasis in JOURNAL OF MOLECULAR MEDICINE
  • 2014-10. Downregulation of PEBP4, a target of miR-34a, sensitizes drug-resistant lung cancer cells in TUMOR BIOLOGY
  • 2013-10. miR-135a/b Modulate Cisplatin Resistance of Human Lung Cancer Cell Line by Targeting MCL1 in PATHOLOGY & ONCOLOGY RESEARCH
  • 2013-07. miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1 in BRITISH JOURNAL OF CANCER
  • 2013-07. Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer in BRITISH JOURNAL OF CANCER
  • 2010-04. Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region in ONCOGENE
  • 2012-12. Dysregulation of MicroRNAs in cancer in JOURNAL OF BIOMEDICAL SCIENCE
  • 2011-04. miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 2013-10. Deregulation of let-7e in epithelial ovarian cancer promotes the development of resistance to cisplatin in ONCOGENESIS
  • 2013-02. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer in ONCOGENE
  • 2011-11. let-7 MicroRNAs Induce Tamoxifen Sensitivity by Downregulation of Estrogen Receptor α Signaling in Breast Cancer in MOLECULAR MEDICINE
  • 2011-08. MicroRNA-mediated drug resistance in breast cancer in CLINICAL EPIGENETICS
  • 2012-09. MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells in ANNALS OF SURGICAL ONCOLOGY
  • 2016-11. Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3 in CELL DEATH & DISEASE
  • 2012-05. The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation in LEUKEMIA
  • 2015-04. miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression in CELL RESEARCH
  • 2011-04. MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma in JOURNAL OF HUMAN GENETICS
  • 2014-12. MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3 in MOLECULAR CANCER
  • 2017-05. Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma in LEUKEMIA
  • 2015-09. MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK in TUMOR BIOLOGY
  • 2005-06. MicroRNA expression profiles classify human cancers in NATURE
  • 2009-10-05. Reversing Agents for ATP-Binding Cassette Drug Transporters in MULTI-DRUG RESISTANCE IN CANCER
  • 2011-12. Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia in MOLECULAR CANCER
  • 2017-10-05. Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer in CELL DEATH & DISEASE
  • 2014-01. MicroRNA-200c Regulates the Sensitivity of Chemotherapy of Gastric Cancer SGC7901/DDP Cells by Directly Targeting RhoE in PATHOLOGY & ONCOLOGY RESEARCH
  • 2017-01. MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy in CELL DEATH & DISEASE
  • 2013-10. Cancer drug resistance: an evolving paradigm in NATURE REVIEWS CANCER
  • 2006-11. MicroRNA signatures in human cancers in NATURE REVIEWS CANCER
  • 2014-12. Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R in BMC CANCER
  • 2012-09. Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B in NATURE MEDICINE
  • 2014-01. The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab in ANNALS OF SURGICAL ONCOLOGY
  • 2013-01. miR-34c may protect lung cancer cells from paclitaxel-induced apoptosis in ONCOGENE
  • 2015-03. miR-15b regulates cisplatin resistance and metastasis by targeting PEBP4 in human lung adenocarcinoma cells in CANCER GENE THERAPY
  • 2012-01. miRNA-34a is associated with docetaxel resistance in human breast cancer cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2014-12. MicroRNA-100 regulates pancreatic cancer cells growth and sensitivity to chemotherapy through targeting FGFR3 in TUMOR BIOLOGY
  • 2014-12. MicroRNA-182 modulates chemosensitivity of human non-small cell lung cancer to cisplatin by targeting PDCD4 in DIAGNOSTIC PATHOLOGY
  • 2012-03. miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2015-02. Indirect modulation of sensitivity to 5-fluorouracil by microRNA-96 in human colorectal cancer cells in ARCHIVES OF PHARMACAL RESEARCH
  • 2014-11. Overexpression of MicroRNA-122 Re-sensitizes 5-FU-Resistant Colon Cancer Cells to 5-FU Through the Inhibition of PKM2 In Vitro and In Vivo in CELL BIOCHEMISTRY AND BIOPHYSICS
  • 2010-11. Multiple Drug Resistance Mechanisms in Cancer in MOLECULAR BIOTECHNOLOGY
  • 2010-08. MicroRNA and drug resistance in CANCER GENE THERAPY
  • 2015-06. MicroRNA biogenesis pathways in cancer in NATURE REVIEWS CANCER
  • 2014-07. MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G1/S transition and apoptosis by targeting p21WAF1/CIP1 in BRITISH JOURNAL OF CANCER
  • 2002-01. Multidrug resistance in cancer: role of ATP–dependent transporters in NATURE REVIEWS CANCER
  • 2014-12. MicroRNA-449a reduces cell survival and enhances cisplatin-induced cytotoxicity via downregulation of NOTCH1 in ovarian cancer cells in TUMOR BIOLOGY
  • 2005-05. MicroRNA biogenesis: coordinated cropping and dicing in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2017-12. Long noncoding RNA MALAT1 regulates autophagy associated chemoresistance via miR-23b-3p sequestration in gastric cancer in MOLECULAR CANCER
  • 2006-10. Principles of micro-RNA production and maturation in ONCOGENE
  • 2017-10-19. miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis in CELL DEATH & DISEASE
  • 2005-06. A microRNA polycistron as a potential human oncogene in NATURE
  • 2016-12. MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer in CELL DEATH & DISEASE
  • 2008-09. Widespread changes in protein synthesis induced by microRNAs in NATURE
  • 2018-02. A miR-20a/MAPK1/c-Myc regulatory feedback loop regulates breast carcinogenesis and chemoresistance in CELL DEATH & DIFFERENTIATION
  • 2012-06. miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells in MEDICAL ONCOLOGY
  • 2013-07. Friend or foe: the role of microRNA in chemotherapy resistance in ACTA PHARMACOLOGICA SINICA
  • 2017-05-11. miR-218-5p restores sensitivity to gemcitabine through PRKCE/MDR1 axis in gallbladder cancer in CELL DEATH & DISEASE
  • 2014-12. miR-101 regulates expression of EZH2 and contributes to progression of and cisplatin resistance in epithelial ovarian cancer in TUMOR BIOLOGY
  • 2014-12. miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells in MOLECULAR CANCER
  • 2015-06. miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2013-08. MiR-106a targets Mcl-1 to suppress cisplatin resistance of ovarian cancer A2780 cells in ACTA ACADEMIAE MEDICINAE WUHAN
  • 2017-12. MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway in SCIENTIFIC REPORTS
  • 2013-03. Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET in ONCOGENESIS
  • 2014-12. MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma in BMC CANCER
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13148-018-0587-8

    DOI

    http://dx.doi.org/10.1186/s13148-018-0587-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112064160

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30744689


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "National Health and Family Planning Commission", 
              "id": "https://www.grid.ac/institutes/grid.453135.5", 
              "name": [
                "Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China", 
                "Key Laboratory of Organ Transplantation, 310003, Hangzhou, Zhejiang Province, China", 
                "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, 310000, Hangzhou, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Si", 
            "givenName": "Wengong", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Zhejiang University", 
              "id": "https://www.grid.ac/institutes/grid.13402.34", 
              "name": [
                "Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shen", 
            "givenName": "Jiaying", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "First Affiliated Hospital Zhejiang University", 
              "id": "https://www.grid.ac/institutes/grid.452661.2", 
              "name": [
                "Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China", 
                "Clinical Research Center, First Affiliated Hospital of Zhejiang University College of Medicine, 310000, Hangzhou, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zheng", 
            "givenName": "Huilin", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical University of South Carolina", 
              "id": "https://www.grid.ac/institutes/grid.259828.c", 
              "name": [
                "Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China", 
                "Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 29425, Charleston, SC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fan", 
            "givenName": "Weimin", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.canlet.2014.10.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000015548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1476-4598-10-108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000206587", 
              "https://doi.org/10.1186/1476-4598-10-108"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-08-0021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000376245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.227611", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000527084"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1746-1596-9-143", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001052331", 
              "https://doi.org/10.1186/1746-1596-9-143"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1476-4598-13-35", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001221401", 
              "https://doi.org/10.1186/1476-4598-13-35"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2016.450", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001295844", 
              "https://doi.org/10.1038/cddis.2016.450"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.critrevonc.2011.03.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001475354"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1014720108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001498014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/1061186x.2015.1015536", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001692102"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/abbs/gms099", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001906812"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biomaterials.2014.04.053", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001947537"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/mc.21832", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002610274"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/leu.2016.325", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002732802", 
              "https://doi.org/10.1038/leu.2016.325"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00109-014-1129-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002816175", 
              "https://doi.org/10.1007/s00109-014-1129-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molonc.2013.09.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003286385"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djn123", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003446650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molonc.2012.10.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003600788"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0165-4608(01)00412-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003740464"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0707351104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003925185"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2012.03.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004151172"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m806041200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004856248"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-60761-416-6_14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005460792", 
              "https://doi.org/10.1007/978-1-60761-416-6_14"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-60761-416-6_14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005460792", 
              "https://doi.org/10.1007/978-1-60761-416-6_14"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2007.10.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005468503"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0039197", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005664674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0034210", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005998839"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11596-013-1160-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006324334", 
              "https://doi.org/10.1007/s11596-013-1160-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0059390", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006869353"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1078-0432.ccr-13-2805", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006902149"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0061858", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007153582"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1015541107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007992906"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1476-4598-13-193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008002053", 
              "https://doi.org/10.1186/1476-4598-13-193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1476-4598-13-193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008002053", 
              "https://doi.org/10.1186/1476-4598-13-193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cr.2015.23", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008234216", 
              "https://doi.org/10.1038/cr.2015.23"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-07-2488", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008557928"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0050469", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008684442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.1202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008828006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/febs.13012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008978352"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.1458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009339461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.1458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009339461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2284-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009339821", 
              "https://doi.org/10.1007/s13277-014-2284-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biomaterials.2014.02.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009401769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2010/821717", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009629786"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-13-0448", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009802116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcp.24366", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009853894"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/oncsis.2013.3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009881059", 
              "https://doi.org/10.1038/oncsis.2013.3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m112.408104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010399155"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0058169", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010554391"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m114.598383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010707876"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3322/caac.21254", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011682275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2013.09.111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012042825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.2594", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012176508"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/carcin/bgp219", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012261114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkn522", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012733286"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3932", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012737365", 
              "https://doi.org/10.1038/nrc3932"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0115565", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013173330"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.307405", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013248167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2009-09-243147", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013451101"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molmed.2006.10.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013571739"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0095716", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014146485"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2407-14-799", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014301343", 
              "https://doi.org/10.1186/1471-2407-14-799"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2014-06-581926", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014465716"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.25191", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014976469"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.25191", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014976469"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10549-015-3372-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015161557", 
              "https://doi.org/10.1007/s10549-015-3372-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1149460", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015783172"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2014.07.026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015917196"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000354521", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016201429"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-06-1403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016407635"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11010-010-0700-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016475677", 
              "https://doi.org/10.1007/s11010-010-0700-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.29168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016580403"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/cad.0000000000000107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016722884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/cad.0000000000000107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016722884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.lungcan.2012.05.107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016870518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.lungcan.2012.05.107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016870518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2014.01.034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017110149"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jconrel.2013.09.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017201017"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm.2890", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017506378", 
              "https://doi.org/10.1038/nm.2890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0039167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017755652"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-013-3325-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018331712", 
              "https://doi.org/10.1245/s10434-013-3325-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-12-0103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018428226"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2014.11.039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018556074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12253-013-9664-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018748837", 
              "https://doi.org/10.1007/s12253-013-9664-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.3563", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019451721"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.24721", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019617692"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2008.07459.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019958546"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0901409", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020263078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2014.03.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020472887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10549-011-1424-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020569096", 
              "https://doi.org/10.1007/s10549-011-1424-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020637207", 
              "https://doi.org/10.1038/nature03552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020637207", 
              "https://doi.org/10.1038/nature03552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.26369", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020966019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m709382200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021086109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12253-013-9630-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021132731", 
              "https://doi.org/10.1007/s12253-013-9630-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/2159-8290.cd-13-0202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021245915"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1124/mol.114.092759", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021282371"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.28774", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021738603"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021877727", 
              "https://doi.org/10.1038/nature07228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-012-2246-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022265670", 
              "https://doi.org/10.1245/s10434-012-2246-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.critrevonc.2006.06.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022288952"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7314/apjcp.2013.14.12.7529", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022412156"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2013.01.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022457868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-12-0463", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022470651"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2012.06.048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022541432"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/excr.2000.4838", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023984846"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7314/apjcp.2014.15.13.5137", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024416336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5483/bmbrep.2014.47.5.165", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024463545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2217/epi.10.74", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024643483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03702", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024825726", 
              "https://doi.org/10.1038/nature03702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03702", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024825726", 
              "https://doi.org/10.1038/nature03702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.25260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024917019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.25260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024917019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m110.216887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025062157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12032-011-9823-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025397903", 
              "https://doi.org/10.1007/s12032-011-9823-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pros.21185", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025568744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pros.21185", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025568744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.242606799", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025755034"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m110.101055", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025781556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3599", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026519625", 
              "https://doi.org/10.1038/nrc3599"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/abbs/gmq125", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026524422"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00280-011-1752-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027219291", 
              "https://doi.org/10.1007/s00280-011-1752-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2013.07.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027485499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0089446", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027755941"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.yexcr.2013.10.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027880680"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12013-014-0062-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028000364", 
              "https://doi.org/10.1007/s12013-014-0062-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/abbs/gmt113", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028333099"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0030560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028864983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-10-0397", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028890591"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2016.11.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029138019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-14-1140", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029802103"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m112.434340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030067633"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc706", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030131756", 
              "https://doi.org/10.1038/nrc706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc706", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030131756", 
              "https://doi.org/10.1038/nrc706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.yexmp.2014.04.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030277666"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2015.04.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030326606"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/path.1706", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030659557"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-05-2352", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030953088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cgt.2014.73", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031118392", 
              "https://doi.org/10.1038/cgt.2014.73"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2014.10.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031155858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2014.10.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031155858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/abbs/gmr128", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031367207"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-06-2698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031596158"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2014.03.105", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031757966"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1535370213497321", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031929364"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1535370213497321", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031929364"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/carcin/bgq192", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031939212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gene.2013.12.043", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032248895"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/mmr.2012.776", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032259727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1423-0127-19-90", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032952819", 
              "https://doi.org/10.1186/1423-0127-19-90"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/jhg.2011.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033112683", 
              "https://doi.org/10.1038/jhg.2011.1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-08-1046", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033400586"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m109.079525", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033622730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/07853890.2015.1043140", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034352770"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/leu.2011.305", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034785758", 
              "https://doi.org/10.1038/leu.2011.305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1644", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035840562", 
              "https://doi.org/10.1038/nrm1644"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1644", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035840562", 
              "https://doi.org/10.1038/nrm1644"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.28782", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035852248"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cncr.26560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035975180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cncr.26560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035975180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/01902148.2011.584263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036263825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/oncsis.2013.39", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036659046", 
              "https://doi.org/10.1038/oncsis.2013.39"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12272-014-0528-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036784531", 
              "https://doi.org/10.1007/s12272-014-0528-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/abbs/gms026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036911491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1124/mol.108.054163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036978857"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0062334", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037217396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/aps.2013.35", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037251119", 
              "https://doi.org/10.1038/aps.2013.35"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2551-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037478052", 
              "https://doi.org/10.1007/s13277-014-2551-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/ijms14010480", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037887889"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajpath.2012.02.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037960748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m109.027466", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038031135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1590/1414-431x20133324", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038184017"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2014.09.018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038309024"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gene.2014.03.049", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038881708"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1535-7163.mct-14-0245", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038901134"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.2013.305", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039301272", 
              "https://doi.org/10.1038/bjc.2013.305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2014.02.073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039541006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2014.02.073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039541006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.26190", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039686474"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.291229", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039691610"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2011.11.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040898961"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13148-011-0040-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040990399", 
              "https://doi.org/10.1007/s13148-011-0040-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2012.51", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041193558", 
              "https://doi.org/10.1038/onc.2012.51"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2013.09.034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041869591"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2271-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042019881", 
              "https://doi.org/10.1007/s13277-014-2271-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3322/caac.20073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042069193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2014.04.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042131250"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-015-3365-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042429921", 
              "https://doi.org/10.1007/s13277-015-3365-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.2014.157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043049899", 
              "https://doi.org/10.1038/bjc.2014.157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.2014.157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043049899", 
              "https://doi.org/10.1038/bjc.2014.157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2585-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043448583", 
              "https://doi.org/10.1007/s13277-014-2585-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2585-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043448583", 
              "https://doi.org/10.1007/s13277-014-2585-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/j.gastro.2007.04.061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043463959"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2014.07.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043610837"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1997", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044012298", 
              "https://doi.org/10.1038/nrc1997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1997", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044012298", 
              "https://doi.org/10.1038/nrc1997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12033-010-9321-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044187462", 
              "https://doi.org/10.1007/s12033-010-9321-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12033-010-9321-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044187462", 
              "https://doi.org/10.1007/s12033-010-9321-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ol.2013.1644", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044207073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ol.2013.1644", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044207073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.med.53.082901.103929", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044382782"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1209908", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044611132", 
              "https://doi.org/10.1038/sj.onc.1209908"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1209908", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044611132", 
              "https://doi.org/10.1038/sj.onc.1209908"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2016.461", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045131344", 
              "https://doi.org/10.1038/cddis.2016.461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0072615", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045268115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.00941-08", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045279634"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7314/apjcp.2014.15.23.10439", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045715624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arcmed.2011.06.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046656231"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-12-3308", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046698073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2010.34", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046878311", 
              "https://doi.org/10.1038/onc.2010.34"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2014.10.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046975622"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.741", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047088831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/mt.2012.180", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047118135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.drup.2013.05.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048088687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2012.06.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048271589"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000374036", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048426237"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4161/cc.21503", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048786567"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0307323101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049808985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2012.128", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050107557", 
              "https://doi.org/10.1038/onc.2012.128"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-10-0145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050520970"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2011.10.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050807350"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2006.04.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050886249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2012.07.127", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051167169"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2014.11.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051756200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1200/jco.2009.24.0317", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051779030"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cgt.2010.18", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051790882", 
              "https://doi.org/10.1038/cgt.2010.18"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2407-14-134", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051927752", 
              "https://doi.org/10.1186/1471-2407-14-134"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.2013.320", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052101127", 
              "https://doi.org/10.1038/bjc.2013.320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0028308", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052468320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m111.265439", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053003575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.07.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053021425"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djt302", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053220493"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci43897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053570320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2016.367", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053593139", 
              "https://doi.org/10.1038/cddis.2016.367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1947601911425832", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064081109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2119/molmed.2010.00225", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068965332", 
              "https://doi.org/10.2119/molmed.2010.00225"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2119/molmed.2010.00225", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068965332", 
              "https://doi.org/10.2119/molmed.2010.00225"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1389200216666151015113400", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069176464"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/138920371604150429154142", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069179673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1389450116666150325231419", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069181477"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ijmm.2013.1439", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071507661"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ijmm.2013.1439", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071507661"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ijo.2012.1418", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071512751"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/mmr.2014.2271", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071521769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/mmr.2014.2271", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071521769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/mmr.2014.2688", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071522086"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/mmr.2014.2688", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071522086"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2011.1472", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071531585"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2012.1823", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071531879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2532", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2532", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2755", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532694"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2755", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532694"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532818"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2897", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532818"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2014.3646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071533461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2014.3646", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071533461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4161/cc.7.16.6533", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072299587"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7785/tcrt.2012.500364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074053007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7785/tcrt.2012.500364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074053007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077823247", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078838078", 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep41942", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083685827", 
              "https://doi.org/10.1038/srep41942"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.15559", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083868131"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.15781", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084372899"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2017.178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085394206", 
              "https://doi.org/10.1038/cddis.2017.178"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1010428317703825", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086105010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1010428317703825", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086105010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1010428317703825", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086105010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2017.08.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091339385"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ol.2017.6982", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091856074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2017.460", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092087163", 
              "https://doi.org/10.1038/cddis.2017.460"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2017.530", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092275539", 
              "https://doi.org/10.1038/cddis.2017.530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.26431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092334203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2017.10.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092438829"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cdd.2017.176", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092618966", 
              "https://doi.org/10.1038/cdd.2017.176"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cdd.2017.176", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092618966", 
              "https://doi.org/10.1038/cdd.2017.176"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0743-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092816273", 
              "https://doi.org/10.1186/s12943-017-0743-3"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-12", 
        "datePublishedReg": "2019-12-01", 
        "description": "MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19-25\u2009nt, which can regulate various target genes and are thus involved in the regulation of a variety of biological and pathological processes, including the formation and development of cancer. Drug resistance in cancer chemotherapy is one of the main obstacles to curing this malignant disease. Statistical data indicate that over 90% of the mortality of patients with cancer is related to drug resistance. Drug resistance of cancer chemotherapy can be caused by many mechanisms, such as decreased antitumor drug uptake, modified drug targets, altered cell cycle checkpoints, or increased DNA damage repair, among others. In recent years, many studies have shown that miRNAs are involved in the drug resistance of tumor cells by targeting drug-resistance-related genes or influencing genes related to cell proliferation, cell cycle, and apoptosis. A single miRNA often targets a number of genes, and its regulatory effect is tissue-specific. In this review, we emphasize the miRNAs that are involved in the regulation of drug resistance among different cancers and probe the mechanisms of the deregulated expression of miRNAs. The molecular targets of miRNAs and their underlying signaling pathways are also explored comprehensively. A holistic understanding of the functions of miRNAs in drug resistance will help us develop better strategies to regulate them efficiently and will finally pave the way toward better translation of miRNAs into clinics, developing them into a promising approach in cancer therapy.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/s13148-018-0587-8", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1042271", 
            "issn": [
              "1868-7075", 
              "1868-7083"
            ], 
            "name": "Clinical Epigenetics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "11"
          }
        ], 
        "name": "The role and mechanisms of action of microRNAs in cancer drug resistance", 
        "pagination": "25", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "222e5acdfdae06a743b067d2c9ac223910be71b3d3dac097938f5071704a4b23"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30744689"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101516977"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s13148-018-0587-8"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1112064160"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s13148-018-0587-8", 
          "https://app.dimensions.ai/details/publication/pub.1112064160"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T09:51", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89789_00000004.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1186%2Fs13148-018-0587-8"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13148-018-0587-8'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13148-018-0587-8'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13148-018-0587-8'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13148-018-0587-8'


     

    This table displays all metadata directly associated to this object as RDF triples.

    892 TRIPLES      21 PREDICATES      273 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s13148-018-0587-8 schema:about anzsrc-for:06
    2 anzsrc-for:0601
    3 schema:author N84d54162a9a544cfb89ee21ff935dd5b
    4 schema:citation sg:pub.10.1007/978-1-60761-416-6_14
    5 sg:pub.10.1007/s00109-014-1129-2
    6 sg:pub.10.1007/s00280-011-1752-3
    7 sg:pub.10.1007/s10549-011-1424-3
    8 sg:pub.10.1007/s10549-015-3372-9
    9 sg:pub.10.1007/s11010-010-0700-6
    10 sg:pub.10.1007/s11596-013-1160-5
    11 sg:pub.10.1007/s12013-014-0062-x
    12 sg:pub.10.1007/s12032-011-9823-1
    13 sg:pub.10.1007/s12033-010-9321-2
    14 sg:pub.10.1007/s12253-013-9630-4
    15 sg:pub.10.1007/s12253-013-9664-7
    16 sg:pub.10.1007/s12272-014-0528-9
    17 sg:pub.10.1007/s13148-011-0040-8
    18 sg:pub.10.1007/s13277-014-2271-8
    19 sg:pub.10.1007/s13277-014-2284-3
    20 sg:pub.10.1007/s13277-014-2551-3
    21 sg:pub.10.1007/s13277-014-2585-6
    22 sg:pub.10.1007/s13277-015-3365-7
    23 sg:pub.10.1038/aps.2013.35
    24 sg:pub.10.1038/bjc.2013.305
    25 sg:pub.10.1038/bjc.2013.320
    26 sg:pub.10.1038/bjc.2014.157
    27 sg:pub.10.1038/cdd.2017.176
    28 sg:pub.10.1038/cddis.2016.367
    29 sg:pub.10.1038/cddis.2016.450
    30 sg:pub.10.1038/cddis.2016.461
    31 sg:pub.10.1038/cddis.2017.178
    32 sg:pub.10.1038/cddis.2017.460
    33 sg:pub.10.1038/cddis.2017.530
    34 sg:pub.10.1038/cgt.2010.18
    35 sg:pub.10.1038/cgt.2014.73
    36 sg:pub.10.1038/cr.2015.23
    37 sg:pub.10.1038/jhg.2011.1
    38 sg:pub.10.1038/leu.2011.305
    39 sg:pub.10.1038/leu.2016.325
    40 sg:pub.10.1038/nature03552
    41 sg:pub.10.1038/nature03702
    42 sg:pub.10.1038/nature07228
    43 sg:pub.10.1038/nm.2890
    44 sg:pub.10.1038/nrc1997
    45 sg:pub.10.1038/nrc3599
    46 sg:pub.10.1038/nrc3932
    47 sg:pub.10.1038/nrc706
    48 sg:pub.10.1038/nrm1644
    49 sg:pub.10.1038/onc.2010.34
    50 sg:pub.10.1038/onc.2012.128
    51 sg:pub.10.1038/onc.2012.51
    52 sg:pub.10.1038/oncsis.2013.3
    53 sg:pub.10.1038/oncsis.2013.39
    54 sg:pub.10.1038/sj.onc.1209908
    55 sg:pub.10.1038/srep41942
    56 sg:pub.10.1186/1423-0127-19-90
    57 sg:pub.10.1186/1471-2407-14-134
    58 sg:pub.10.1186/1471-2407-14-799
    59 sg:pub.10.1186/1476-4598-10-108
    60 sg:pub.10.1186/1476-4598-13-193
    61 sg:pub.10.1186/1476-4598-13-35
    62 sg:pub.10.1186/1746-1596-9-143
    63 sg:pub.10.1186/s12943-017-0743-3
    64 sg:pub.10.1245/s10434-012-2246-1
    65 sg:pub.10.1245/s10434-013-3325-7
    66 sg:pub.10.2119/molmed.2010.00225
    67 https://app.dimensions.ai/details/publication/pub.1077823247
    68 https://app.dimensions.ai/details/publication/pub.1078838078
    69 https://doi.org/10.1002/cncr.26560
    70 https://doi.org/10.1002/hep.26369
    71 https://doi.org/10.1002/ijc.25191
    72 https://doi.org/10.1002/ijc.25260
    73 https://doi.org/10.1002/ijc.26190
    74 https://doi.org/10.1002/ijc.28774
    75 https://doi.org/10.1002/ijc.28782
    76 https://doi.org/10.1002/ijc.29168
    77 https://doi.org/10.1002/jcb.24721
    78 https://doi.org/10.1002/jcb.26431
    79 https://doi.org/10.1002/jcp.24366
    80 https://doi.org/10.1002/mc.21832
    81 https://doi.org/10.1002/path.1706
    82 https://doi.org/10.1002/pros.21185
    83 https://doi.org/10.1002/stem.741
    84 https://doi.org/10.1006/excr.2000.4838
    85 https://doi.org/10.1016/j.ajpath.2012.02.024
    86 https://doi.org/10.1016/j.arcmed.2011.06.008
    87 https://doi.org/10.1016/j.bbrc.2012.06.048
    88 https://doi.org/10.1016/j.bbrc.2012.07.127
    89 https://doi.org/10.1016/j.bbrc.2013.09.111
    90 https://doi.org/10.1016/j.bbrc.2014.02.073
    91 https://doi.org/10.1016/j.bbrc.2014.03.105
    92 https://doi.org/10.1016/j.bbrc.2014.11.039
    93 https://doi.org/10.1016/j.bbrc.2015.04.023
    94 https://doi.org/10.1016/j.biomaterials.2014.02.006
    95 https://doi.org/10.1016/j.biomaterials.2014.04.053
    96 https://doi.org/10.1016/j.canlet.2011.11.024
    97 https://doi.org/10.1016/j.canlet.2013.07.016
    98 https://doi.org/10.1016/j.canlet.2013.09.034
    99 https://doi.org/10.1016/j.canlet.2014.07.004
    100 https://doi.org/10.1016/j.canlet.2014.07.026
    101 https://doi.org/10.1016/j.canlet.2014.10.006
    102 https://doi.org/10.1016/j.canlet.2014.10.007
    103 https://doi.org/10.1016/j.canlet.2014.11.051
    104 https://doi.org/10.1016/j.canlet.2016.11.017
    105 https://doi.org/10.1016/j.canlet.2017.08.027
    106 https://doi.org/10.1016/j.canlet.2017.10.022
    107 https://doi.org/10.1016/j.ccell.2014.10.010
    108 https://doi.org/10.1016/j.ccr.2006.04.020
    109 https://doi.org/10.1016/j.ccr.2007.10.028
    110 https://doi.org/10.1016/j.ccr.2014.03.010
    111 https://doi.org/10.1016/j.cell.2011.07.014
    112 https://doi.org/10.1016/j.cell.2012.06.013
    113 https://doi.org/10.1016/j.critrevonc.2006.06.001
    114 https://doi.org/10.1016/j.critrevonc.2011.03.010
    115 https://doi.org/10.1016/j.drup.2013.05.001
    116 https://doi.org/10.1016/j.febslet.2012.03.006
    117 https://doi.org/10.1016/j.febslet.2013.01.016
    118 https://doi.org/10.1016/j.febslet.2014.04.024
    119 https://doi.org/10.1016/j.gene.2013.12.043
    120 https://doi.org/10.1016/j.gene.2014.03.049
    121 https://doi.org/10.1016/j.jconrel.2013.09.015
    122 https://doi.org/10.1016/j.lungcan.2012.05.107
    123 https://doi.org/10.1016/j.molcel.2014.09.018
    124 https://doi.org/10.1016/j.molmed.2006.10.006
    125 https://doi.org/10.1016/j.molonc.2012.10.011
    126 https://doi.org/10.1016/j.molonc.2013.09.004
    127 https://doi.org/10.1016/j.yexcr.2013.10.014
    128 https://doi.org/10.1016/j.yexmp.2014.04.008
    129 https://doi.org/10.1016/j.ygyno.2011.10.013
    130 https://doi.org/10.1016/j.ygyno.2014.01.034
    131 https://doi.org/10.1016/s0165-4608(01)00412-5
    132 https://doi.org/10.1038/mt.2012.180
    133 https://doi.org/10.1053/j.gastro.2007.04.061
    134 https://doi.org/10.1056/nejmoa0901409
    135 https://doi.org/10.1073/pnas.0307323101
    136 https://doi.org/10.1073/pnas.0707351104
    137 https://doi.org/10.1073/pnas.1014720108
    138 https://doi.org/10.1073/pnas.1015541107
    139 https://doi.org/10.1073/pnas.242606799
    140 https://doi.org/10.1074/jbc.m109.027466
    141 https://doi.org/10.1074/jbc.m109.079525
    142 https://doi.org/10.1074/jbc.m110.101055
    143 https://doi.org/10.1074/jbc.m110.216887
    144 https://doi.org/10.1074/jbc.m111.227611
    145 https://doi.org/10.1074/jbc.m111.265439
    146 https://doi.org/10.1074/jbc.m111.291229
    147 https://doi.org/10.1074/jbc.m111.307405
    148 https://doi.org/10.1074/jbc.m112.408104
    149 https://doi.org/10.1074/jbc.m112.434340
    150 https://doi.org/10.1074/jbc.m114.598383
    151 https://doi.org/10.1074/jbc.m709382200
    152 https://doi.org/10.1074/jbc.m806041200
    153 https://doi.org/10.1093/abbs/gmq125
    154 https://doi.org/10.1093/abbs/gmr128
    155 https://doi.org/10.1093/abbs/gms026
    156 https://doi.org/10.1093/abbs/gms099
    157 https://doi.org/10.1093/abbs/gmt113
    158 https://doi.org/10.1093/carcin/bgp219
    159 https://doi.org/10.1093/carcin/bgq192
    160 https://doi.org/10.1093/jnci/djn123
    161 https://doi.org/10.1093/jnci/djt302
    162 https://doi.org/10.1093/nar/gkn522
    163 https://doi.org/10.1097/cad.0000000000000107
    164 https://doi.org/10.1111/febs.13012
    165 https://doi.org/10.1111/j.1365-2141.2008.07459.x
    166 https://doi.org/10.1124/mol.108.054163
    167 https://doi.org/10.1124/mol.114.092759
    168 https://doi.org/10.1126/science.1149460
    169 https://doi.org/10.1128/mcb.00941-08
    170 https://doi.org/10.1146/annurev.med.53.082901.103929
    171 https://doi.org/10.1155/2010/821717
    172 https://doi.org/10.1158/0008-5472.can-05-2352
    173 https://doi.org/10.1158/0008-5472.can-06-1403
    174 https://doi.org/10.1158/0008-5472.can-06-2698
    175 https://doi.org/10.1158/0008-5472.can-07-2488
    176 https://doi.org/10.1158/0008-5472.can-10-0145
    177 https://doi.org/10.1158/0008-5472.can-12-0103
    178 https://doi.org/10.1158/0008-5472.can-12-3308
    179 https://doi.org/10.1158/0008-5472.can-14-1140
    180 https://doi.org/10.1158/1078-0432.ccr-13-2805
    181 https://doi.org/10.1158/1535-7163.mct-08-0021
    182 https://doi.org/10.1158/1535-7163.mct-08-1046
    183 https://doi.org/10.1158/1535-7163.mct-10-0397
    184 https://doi.org/10.1158/1535-7163.mct-12-0463
    185 https://doi.org/10.1158/1535-7163.mct-13-0448
    186 https://doi.org/10.1158/1535-7163.mct-14-0245
    187 https://doi.org/10.1158/2159-8290.cd-13-0202
    188 https://doi.org/10.1159/000354521
    189 https://doi.org/10.1159/000374036
    190 https://doi.org/10.1172/jci43897
    191 https://doi.org/10.1177/1010428317703825
    192 https://doi.org/10.1177/1535370213497321
    193 https://doi.org/10.1177/1947601911425832
    194 https://doi.org/10.1182/blood-2009-09-243147
    195 https://doi.org/10.1182/blood-2014-06-581926
    196 https://doi.org/10.1200/jco.2009.24.0317
    197 https://doi.org/10.1371/journal.pone.0028308
    198 https://doi.org/10.1371/journal.pone.0030560
    199 https://doi.org/10.1371/journal.pone.0034210
    200 https://doi.org/10.1371/journal.pone.0039167
    201 https://doi.org/10.1371/journal.pone.0039197
    202 https://doi.org/10.1371/journal.pone.0050469
    203 https://doi.org/10.1371/journal.pone.0058169
    204 https://doi.org/10.1371/journal.pone.0059390
    205 https://doi.org/10.1371/journal.pone.0061858
    206 https://doi.org/10.1371/journal.pone.0062334
    207 https://doi.org/10.1371/journal.pone.0072615
    208 https://doi.org/10.1371/journal.pone.0089446
    209 https://doi.org/10.1371/journal.pone.0095716
    210 https://doi.org/10.1371/journal.pone.0115565
    211 https://doi.org/10.1590/1414-431x20133324
    212 https://doi.org/10.18632/oncotarget.1202
    213 https://doi.org/10.18632/oncotarget.1458
    214 https://doi.org/10.18632/oncotarget.15559
    215 https://doi.org/10.18632/oncotarget.15781
    216 https://doi.org/10.18632/oncotarget.2594
    217 https://doi.org/10.18632/oncotarget.3563
    218 https://doi.org/10.2174/1389200216666151015113400
    219 https://doi.org/10.2174/138920371604150429154142
    220 https://doi.org/10.2174/1389450116666150325231419
    221 https://doi.org/10.2217/epi.10.74
    222 https://doi.org/10.3109/01902148.2011.584263
    223 https://doi.org/10.3109/07853890.2015.1043140
    224 https://doi.org/10.3109/1061186x.2015.1015536
    225 https://doi.org/10.3322/caac.20073
    226 https://doi.org/10.3322/caac.21254
    227 https://doi.org/10.3390/ijms14010480
    228 https://doi.org/10.3892/ijmm.2013.1439
    229 https://doi.org/10.3892/ijo.2012.1418
    230 https://doi.org/10.3892/mmr.2012.776
    231 https://doi.org/10.3892/mmr.2014.2271
    232 https://doi.org/10.3892/mmr.2014.2688
    233 https://doi.org/10.3892/ol.2013.1644
    234 https://doi.org/10.3892/ol.2017.6982
    235 https://doi.org/10.3892/or.2011.1472
    236 https://doi.org/10.3892/or.2012.1823
    237 https://doi.org/10.3892/or.2013.2532
    238 https://doi.org/10.3892/or.2013.2755
    239 https://doi.org/10.3892/or.2013.2897
    240 https://doi.org/10.3892/or.2014.3646
    241 https://doi.org/10.4161/cc.21503
    242 https://doi.org/10.4161/cc.7.16.6533
    243 https://doi.org/10.5483/bmbrep.2014.47.5.165
    244 https://doi.org/10.7314/apjcp.2013.14.12.7529
    245 https://doi.org/10.7314/apjcp.2014.15.13.5137
    246 https://doi.org/10.7314/apjcp.2014.15.23.10439
    247 https://doi.org/10.7785/tcrt.2012.500364
    248 schema:datePublished 2019-12
    249 schema:datePublishedReg 2019-12-01
    250 schema:description MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19-25 nt, which can regulate various target genes and are thus involved in the regulation of a variety of biological and pathological processes, including the formation and development of cancer. Drug resistance in cancer chemotherapy is one of the main obstacles to curing this malignant disease. Statistical data indicate that over 90% of the mortality of patients with cancer is related to drug resistance. Drug resistance of cancer chemotherapy can be caused by many mechanisms, such as decreased antitumor drug uptake, modified drug targets, altered cell cycle checkpoints, or increased DNA damage repair, among others. In recent years, many studies have shown that miRNAs are involved in the drug resistance of tumor cells by targeting drug-resistance-related genes or influencing genes related to cell proliferation, cell cycle, and apoptosis. A single miRNA often targets a number of genes, and its regulatory effect is tissue-specific. In this review, we emphasize the miRNAs that are involved in the regulation of drug resistance among different cancers and probe the mechanisms of the deregulated expression of miRNAs. The molecular targets of miRNAs and their underlying signaling pathways are also explored comprehensively. A holistic understanding of the functions of miRNAs in drug resistance will help us develop better strategies to regulate them efficiently and will finally pave the way toward better translation of miRNAs into clinics, developing them into a promising approach in cancer therapy.
    251 schema:genre research_article
    252 schema:inLanguage en
    253 schema:isAccessibleForFree true
    254 schema:isPartOf Na4b9216f5b19484d919841fb3dea5135
    255 Nc591c5220ae84274817e12d98ea53ee6
    256 sg:journal.1042271
    257 schema:name The role and mechanisms of action of microRNAs in cancer drug resistance
    258 schema:pagination 25
    259 schema:productId N6719552b7bf64fb6aa4c93174ec4d7fb
    260 N6eb8e35b0dba407698e00ef10fb7992c
    261 N9d216a0d1e2a48268ccf3a06bd927c3b
    262 N9fec92ac949f434cb404829e25318db6
    263 Na9507147362448a9bb98e0a29bc455e2
    264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112064160
    265 https://doi.org/10.1186/s13148-018-0587-8
    266 schema:sdDatePublished 2019-04-11T09:51
    267 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    268 schema:sdPublisher N3e08550db3434029b8a8fb15324ed052
    269 schema:url https://link.springer.com/10.1186%2Fs13148-018-0587-8
    270 sgo:license sg:explorer/license/
    271 sgo:sdDataset articles
    272 rdf:type schema:ScholarlyArticle
    273 N021516b4b8e44c8fadb17b7a2ce44e4a rdf:first N09d3021a9dcc44e8a7e763372daa2041
    274 rdf:rest N96369b03cdf746b2999d9a95bbffef1c
    275 N09d3021a9dcc44e8a7e763372daa2041 schema:affiliation https://www.grid.ac/institutes/grid.452661.2
    276 schema:familyName Zheng
    277 schema:givenName Huilin
    278 rdf:type schema:Person
    279 N24bc535f6d1148d68d03524bfedd0cef schema:affiliation https://www.grid.ac/institutes/grid.13402.34
    280 schema:familyName Shen
    281 schema:givenName Jiaying
    282 rdf:type schema:Person
    283 N3e08550db3434029b8a8fb15324ed052 schema:name Springer Nature - SN SciGraph project
    284 rdf:type schema:Organization
    285 N48578563166f46e2b05529e8d2fb7824 schema:affiliation https://www.grid.ac/institutes/grid.259828.c
    286 schema:familyName Fan
    287 schema:givenName Weimin
    288 rdf:type schema:Person
    289 N6719552b7bf64fb6aa4c93174ec4d7fb schema:name doi
    290 schema:value 10.1186/s13148-018-0587-8
    291 rdf:type schema:PropertyValue
    292 N6eb8e35b0dba407698e00ef10fb7992c schema:name nlm_unique_id
    293 schema:value 101516977
    294 rdf:type schema:PropertyValue
    295 N788439e42d9d429b839e6e56b4935939 rdf:first N24bc535f6d1148d68d03524bfedd0cef
    296 rdf:rest N021516b4b8e44c8fadb17b7a2ce44e4a
    297 N84d54162a9a544cfb89ee21ff935dd5b rdf:first Nb3674f9ecbec465ca4b97014144c7af2
    298 rdf:rest N788439e42d9d429b839e6e56b4935939
    299 N96369b03cdf746b2999d9a95bbffef1c rdf:first N48578563166f46e2b05529e8d2fb7824
    300 rdf:rest rdf:nil
    301 N9d216a0d1e2a48268ccf3a06bd927c3b schema:name pubmed_id
    302 schema:value 30744689
    303 rdf:type schema:PropertyValue
    304 N9fec92ac949f434cb404829e25318db6 schema:name readcube_id
    305 schema:value 222e5acdfdae06a743b067d2c9ac223910be71b3d3dac097938f5071704a4b23
    306 rdf:type schema:PropertyValue
    307 Na4b9216f5b19484d919841fb3dea5135 schema:volumeNumber 11
    308 rdf:type schema:PublicationVolume
    309 Na9507147362448a9bb98e0a29bc455e2 schema:name dimensions_id
    310 schema:value pub.1112064160
    311 rdf:type schema:PropertyValue
    312 Nb3674f9ecbec465ca4b97014144c7af2 schema:affiliation https://www.grid.ac/institutes/grid.453135.5
    313 schema:familyName Si
    314 schema:givenName Wengong
    315 rdf:type schema:Person
    316 Nc591c5220ae84274817e12d98ea53ee6 schema:issueNumber 1
    317 rdf:type schema:PublicationIssue
    318 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    319 schema:name Biological Sciences
    320 rdf:type schema:DefinedTerm
    321 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    322 schema:name Biochemistry and Cell Biology
    323 rdf:type schema:DefinedTerm
    324 sg:journal.1042271 schema:issn 1868-7075
    325 1868-7083
    326 schema:name Clinical Epigenetics
    327 rdf:type schema:Periodical
    328 sg:pub.10.1007/978-1-60761-416-6_14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005460792
    329 https://doi.org/10.1007/978-1-60761-416-6_14
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1007/s00109-014-1129-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002816175
    332 https://doi.org/10.1007/s00109-014-1129-2
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1007/s00280-011-1752-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027219291
    335 https://doi.org/10.1007/s00280-011-1752-3
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1007/s10549-011-1424-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020569096
    338 https://doi.org/10.1007/s10549-011-1424-3
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1007/s10549-015-3372-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015161557
    341 https://doi.org/10.1007/s10549-015-3372-9
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1007/s11010-010-0700-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016475677
    344 https://doi.org/10.1007/s11010-010-0700-6
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1007/s11596-013-1160-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006324334
    347 https://doi.org/10.1007/s11596-013-1160-5
    348 rdf:type schema:CreativeWork
    349 sg:pub.10.1007/s12013-014-0062-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028000364
    350 https://doi.org/10.1007/s12013-014-0062-x
    351 rdf:type schema:CreativeWork
    352 sg:pub.10.1007/s12032-011-9823-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025397903
    353 https://doi.org/10.1007/s12032-011-9823-1
    354 rdf:type schema:CreativeWork
    355 sg:pub.10.1007/s12033-010-9321-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044187462
    356 https://doi.org/10.1007/s12033-010-9321-2
    357 rdf:type schema:CreativeWork
    358 sg:pub.10.1007/s12253-013-9630-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021132731
    359 https://doi.org/10.1007/s12253-013-9630-4
    360 rdf:type schema:CreativeWork
    361 sg:pub.10.1007/s12253-013-9664-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018748837
    362 https://doi.org/10.1007/s12253-013-9664-7
    363 rdf:type schema:CreativeWork
    364 sg:pub.10.1007/s12272-014-0528-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036784531
    365 https://doi.org/10.1007/s12272-014-0528-9
    366 rdf:type schema:CreativeWork
    367 sg:pub.10.1007/s13148-011-0040-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040990399
    368 https://doi.org/10.1007/s13148-011-0040-8
    369 rdf:type schema:CreativeWork
    370 sg:pub.10.1007/s13277-014-2271-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042019881
    371 https://doi.org/10.1007/s13277-014-2271-8
    372 rdf:type schema:CreativeWork
    373 sg:pub.10.1007/s13277-014-2284-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009339821
    374 https://doi.org/10.1007/s13277-014-2284-3
    375 rdf:type schema:CreativeWork
    376 sg:pub.10.1007/s13277-014-2551-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037478052
    377 https://doi.org/10.1007/s13277-014-2551-3
    378 rdf:type schema:CreativeWork
    379 sg:pub.10.1007/s13277-014-2585-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043448583
    380 https://doi.org/10.1007/s13277-014-2585-6
    381 rdf:type schema:CreativeWork
    382 sg:pub.10.1007/s13277-015-3365-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042429921
    383 https://doi.org/10.1007/s13277-015-3365-7
    384 rdf:type schema:CreativeWork
    385 sg:pub.10.1038/aps.2013.35 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037251119
    386 https://doi.org/10.1038/aps.2013.35
    387 rdf:type schema:CreativeWork
    388 sg:pub.10.1038/bjc.2013.305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039301272
    389 https://doi.org/10.1038/bjc.2013.305
    390 rdf:type schema:CreativeWork
    391 sg:pub.10.1038/bjc.2013.320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052101127
    392 https://doi.org/10.1038/bjc.2013.320
    393 rdf:type schema:CreativeWork
    394 sg:pub.10.1038/bjc.2014.157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043049899
    395 https://doi.org/10.1038/bjc.2014.157
    396 rdf:type schema:CreativeWork
    397 sg:pub.10.1038/cdd.2017.176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092618966
    398 https://doi.org/10.1038/cdd.2017.176
    399 rdf:type schema:CreativeWork
    400 sg:pub.10.1038/cddis.2016.367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053593139
    401 https://doi.org/10.1038/cddis.2016.367
    402 rdf:type schema:CreativeWork
    403 sg:pub.10.1038/cddis.2016.450 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001295844
    404 https://doi.org/10.1038/cddis.2016.450
    405 rdf:type schema:CreativeWork
    406 sg:pub.10.1038/cddis.2016.461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045131344
    407 https://doi.org/10.1038/cddis.2016.461
    408 rdf:type schema:CreativeWork
    409 sg:pub.10.1038/cddis.2017.178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085394206
    410 https://doi.org/10.1038/cddis.2017.178
    411 rdf:type schema:CreativeWork
    412 sg:pub.10.1038/cddis.2017.460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092087163
    413 https://doi.org/10.1038/cddis.2017.460
    414 rdf:type schema:CreativeWork
    415 sg:pub.10.1038/cddis.2017.530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092275539
    416 https://doi.org/10.1038/cddis.2017.530
    417 rdf:type schema:CreativeWork
    418 sg:pub.10.1038/cgt.2010.18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051790882
    419 https://doi.org/10.1038/cgt.2010.18
    420 rdf:type schema:CreativeWork
    421 sg:pub.10.1038/cgt.2014.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031118392
    422 https://doi.org/10.1038/cgt.2014.73
    423 rdf:type schema:CreativeWork
    424 sg:pub.10.1038/cr.2015.23 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008234216
    425 https://doi.org/10.1038/cr.2015.23
    426 rdf:type schema:CreativeWork
    427 sg:pub.10.1038/jhg.2011.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033112683
    428 https://doi.org/10.1038/jhg.2011.1
    429 rdf:type schema:CreativeWork
    430 sg:pub.10.1038/leu.2011.305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034785758
    431 https://doi.org/10.1038/leu.2011.305
    432 rdf:type schema:CreativeWork
    433 sg:pub.10.1038/leu.2016.325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002732802
    434 https://doi.org/10.1038/leu.2016.325
    435 rdf:type schema:CreativeWork
    436 sg:pub.10.1038/nature03552 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020637207
    437 https://doi.org/10.1038/nature03552
    438 rdf:type schema:CreativeWork
    439 sg:pub.10.1038/nature03702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024825726
    440 https://doi.org/10.1038/nature03702
    441 rdf:type schema:CreativeWork
    442 sg:pub.10.1038/nature07228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021877727
    443 https://doi.org/10.1038/nature07228
    444 rdf:type schema:CreativeWork
    445 sg:pub.10.1038/nm.2890 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017506378
    446 https://doi.org/10.1038/nm.2890
    447 rdf:type schema:CreativeWork
    448 sg:pub.10.1038/nrc1997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044012298
    449 https://doi.org/10.1038/nrc1997
    450 rdf:type schema:CreativeWork
    451 sg:pub.10.1038/nrc3599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026519625
    452 https://doi.org/10.1038/nrc3599
    453 rdf:type schema:CreativeWork
    454 sg:pub.10.1038/nrc3932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012737365
    455 https://doi.org/10.1038/nrc3932
    456 rdf:type schema:CreativeWork
    457 sg:pub.10.1038/nrc706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030131756
    458 https://doi.org/10.1038/nrc706
    459 rdf:type schema:CreativeWork
    460 sg:pub.10.1038/nrm1644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035840562
    461 https://doi.org/10.1038/nrm1644
    462 rdf:type schema:CreativeWork
    463 sg:pub.10.1038/onc.2010.34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046878311
    464 https://doi.org/10.1038/onc.2010.34
    465 rdf:type schema:CreativeWork
    466 sg:pub.10.1038/onc.2012.128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050107557
    467 https://doi.org/10.1038/onc.2012.128
    468 rdf:type schema:CreativeWork
    469 sg:pub.10.1038/onc.2012.51 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041193558
    470 https://doi.org/10.1038/onc.2012.51
    471 rdf:type schema:CreativeWork
    472 sg:pub.10.1038/oncsis.2013.3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009881059
    473 https://doi.org/10.1038/oncsis.2013.3
    474 rdf:type schema:CreativeWork
    475 sg:pub.10.1038/oncsis.2013.39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036659046
    476 https://doi.org/10.1038/oncsis.2013.39
    477 rdf:type schema:CreativeWork
    478 sg:pub.10.1038/sj.onc.1209908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044611132
    479 https://doi.org/10.1038/sj.onc.1209908
    480 rdf:type schema:CreativeWork
    481 sg:pub.10.1038/srep41942 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083685827
    482 https://doi.org/10.1038/srep41942
    483 rdf:type schema:CreativeWork
    484 sg:pub.10.1186/1423-0127-19-90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032952819
    485 https://doi.org/10.1186/1423-0127-19-90
    486 rdf:type schema:CreativeWork
    487 sg:pub.10.1186/1471-2407-14-134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051927752
    488 https://doi.org/10.1186/1471-2407-14-134
    489 rdf:type schema:CreativeWork
    490 sg:pub.10.1186/1471-2407-14-799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014301343
    491 https://doi.org/10.1186/1471-2407-14-799
    492 rdf:type schema:CreativeWork
    493 sg:pub.10.1186/1476-4598-10-108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000206587
    494 https://doi.org/10.1186/1476-4598-10-108
    495 rdf:type schema:CreativeWork
    496 sg:pub.10.1186/1476-4598-13-193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008002053
    497 https://doi.org/10.1186/1476-4598-13-193
    498 rdf:type schema:CreativeWork
    499 sg:pub.10.1186/1476-4598-13-35 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001221401
    500 https://doi.org/10.1186/1476-4598-13-35
    501 rdf:type schema:CreativeWork
    502 sg:pub.10.1186/1746-1596-9-143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001052331
    503 https://doi.org/10.1186/1746-1596-9-143
    504 rdf:type schema:CreativeWork
    505 sg:pub.10.1186/s12943-017-0743-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092816273
    506 https://doi.org/10.1186/s12943-017-0743-3
    507 rdf:type schema:CreativeWork
    508 sg:pub.10.1245/s10434-012-2246-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022265670
    509 https://doi.org/10.1245/s10434-012-2246-1
    510 rdf:type schema:CreativeWork
    511 sg:pub.10.1245/s10434-013-3325-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018331712
    512 https://doi.org/10.1245/s10434-013-3325-7
    513 rdf:type schema:CreativeWork
    514 sg:pub.10.2119/molmed.2010.00225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068965332
    515 https://doi.org/10.2119/molmed.2010.00225
    516 rdf:type schema:CreativeWork
    517 https://app.dimensions.ai/details/publication/pub.1077823247 schema:CreativeWork
    518 https://app.dimensions.ai/details/publication/pub.1078838078 schema:CreativeWork
    519 https://doi.org/10.1002/cncr.26560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035975180
    520 rdf:type schema:CreativeWork
    521 https://doi.org/10.1002/hep.26369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020966019
    522 rdf:type schema:CreativeWork
    523 https://doi.org/10.1002/ijc.25191 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014976469
    524 rdf:type schema:CreativeWork
    525 https://doi.org/10.1002/ijc.25260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024917019
    526 rdf:type schema:CreativeWork
    527 https://doi.org/10.1002/ijc.26190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039686474
    528 rdf:type schema:CreativeWork
    529 https://doi.org/10.1002/ijc.28774 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021738603
    530 rdf:type schema:CreativeWork
    531 https://doi.org/10.1002/ijc.28782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035852248
    532 rdf:type schema:CreativeWork
    533 https://doi.org/10.1002/ijc.29168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016580403
    534 rdf:type schema:CreativeWork
    535 https://doi.org/10.1002/jcb.24721 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019617692
    536 rdf:type schema:CreativeWork
    537 https://doi.org/10.1002/jcb.26431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092334203
    538 rdf:type schema:CreativeWork
    539 https://doi.org/10.1002/jcp.24366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009853894
    540 rdf:type schema:CreativeWork
    541 https://doi.org/10.1002/mc.21832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002610274
    542 rdf:type schema:CreativeWork
    543 https://doi.org/10.1002/path.1706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030659557
    544 rdf:type schema:CreativeWork
    545 https://doi.org/10.1002/pros.21185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025568744
    546 rdf:type schema:CreativeWork
    547 https://doi.org/10.1002/stem.741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047088831
    548 rdf:type schema:CreativeWork
    549 https://doi.org/10.1006/excr.2000.4838 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023984846
    550 rdf:type schema:CreativeWork
    551 https://doi.org/10.1016/j.ajpath.2012.02.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037960748
    552 rdf:type schema:CreativeWork
    553 https://doi.org/10.1016/j.arcmed.2011.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046656231
    554 rdf:type schema:CreativeWork
    555 https://doi.org/10.1016/j.bbrc.2012.06.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022541432
    556 rdf:type schema:CreativeWork
    557 https://doi.org/10.1016/j.bbrc.2012.07.127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051167169
    558 rdf:type schema:CreativeWork
    559 https://doi.org/10.1016/j.bbrc.2013.09.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012042825
    560 rdf:type schema:CreativeWork
    561 https://doi.org/10.1016/j.bbrc.2014.02.073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039541006
    562 rdf:type schema:CreativeWork
    563 https://doi.org/10.1016/j.bbrc.2014.03.105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031757966
    564 rdf:type schema:CreativeWork
    565 https://doi.org/10.1016/j.bbrc.2014.11.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018556074
    566 rdf:type schema:CreativeWork
    567 https://doi.org/10.1016/j.bbrc.2015.04.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030326606
    568 rdf:type schema:CreativeWork
    569 https://doi.org/10.1016/j.biomaterials.2014.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009401769
    570 rdf:type schema:CreativeWork
    571 https://doi.org/10.1016/j.biomaterials.2014.04.053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001947537
    572 rdf:type schema:CreativeWork
    573 https://doi.org/10.1016/j.canlet.2011.11.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040898961
    574 rdf:type schema:CreativeWork
    575 https://doi.org/10.1016/j.canlet.2013.07.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027485499
    576 rdf:type schema:CreativeWork
    577 https://doi.org/10.1016/j.canlet.2013.09.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041869591
    578 rdf:type schema:CreativeWork
    579 https://doi.org/10.1016/j.canlet.2014.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043610837
    580 rdf:type schema:CreativeWork
    581 https://doi.org/10.1016/j.canlet.2014.07.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015917196
    582 rdf:type schema:CreativeWork
    583 https://doi.org/10.1016/j.canlet.2014.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000015548
    584 rdf:type schema:CreativeWork
    585 https://doi.org/10.1016/j.canlet.2014.10.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046975622
    586 rdf:type schema:CreativeWork
    587 https://doi.org/10.1016/j.canlet.2014.11.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051756200
    588 rdf:type schema:CreativeWork
    589 https://doi.org/10.1016/j.canlet.2016.11.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029138019
    590 rdf:type schema:CreativeWork
    591 https://doi.org/10.1016/j.canlet.2017.08.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091339385
    592 rdf:type schema:CreativeWork
    593 https://doi.org/10.1016/j.canlet.2017.10.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092438829
    594 rdf:type schema:CreativeWork
    595 https://doi.org/10.1016/j.ccell.2014.10.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031155858
    596 rdf:type schema:CreativeWork
    597 https://doi.org/10.1016/j.ccr.2006.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050886249
    598 rdf:type schema:CreativeWork
    599 https://doi.org/10.1016/j.ccr.2007.10.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005468503
    600 rdf:type schema:CreativeWork
    601 https://doi.org/10.1016/j.ccr.2014.03.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020472887
    602 rdf:type schema:CreativeWork
    603 https://doi.org/10.1016/j.cell.2011.07.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053021425
    604 rdf:type schema:CreativeWork
    605 https://doi.org/10.1016/j.cell.2012.06.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048271589
    606 rdf:type schema:CreativeWork
    607 https://doi.org/10.1016/j.critrevonc.2006.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022288952
    608 rdf:type schema:CreativeWork
    609 https://doi.org/10.1016/j.critrevonc.2011.03.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001475354
    610 rdf:type schema:CreativeWork
    611 https://doi.org/10.1016/j.drup.2013.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048088687
    612 rdf:type schema:CreativeWork
    613 https://doi.org/10.1016/j.febslet.2012.03.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004151172
    614 rdf:type schema:CreativeWork
    615 https://doi.org/10.1016/j.febslet.2013.01.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022457868
    616 rdf:type schema:CreativeWork
    617 https://doi.org/10.1016/j.febslet.2014.04.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042131250
    618 rdf:type schema:CreativeWork
    619 https://doi.org/10.1016/j.gene.2013.12.043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032248895
    620 rdf:type schema:CreativeWork
    621 https://doi.org/10.1016/j.gene.2014.03.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038881708
    622 rdf:type schema:CreativeWork
    623 https://doi.org/10.1016/j.jconrel.2013.09.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017201017
    624 rdf:type schema:CreativeWork
    625 https://doi.org/10.1016/j.lungcan.2012.05.107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016870518
    626 rdf:type schema:CreativeWork
    627 https://doi.org/10.1016/j.molcel.2014.09.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038309024
    628 rdf:type schema:CreativeWork
    629 https://doi.org/10.1016/j.molmed.2006.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013571739
    630 rdf:type schema:CreativeWork
    631 https://doi.org/10.1016/j.molonc.2012.10.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003600788
    632 rdf:type schema:CreativeWork
    633 https://doi.org/10.1016/j.molonc.2013.09.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003286385
    634 rdf:type schema:CreativeWork
    635 https://doi.org/10.1016/j.yexcr.2013.10.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027880680
    636 rdf:type schema:CreativeWork
    637 https://doi.org/10.1016/j.yexmp.2014.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030277666
    638 rdf:type schema:CreativeWork
    639 https://doi.org/10.1016/j.ygyno.2011.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050807350
    640 rdf:type schema:CreativeWork
    641 https://doi.org/10.1016/j.ygyno.2014.01.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017110149
    642 rdf:type schema:CreativeWork
    643 https://doi.org/10.1016/s0165-4608(01)00412-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003740464
    644 rdf:type schema:CreativeWork
    645 https://doi.org/10.1038/mt.2012.180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047118135
    646 rdf:type schema:CreativeWork
    647 https://doi.org/10.1053/j.gastro.2007.04.061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043463959
    648 rdf:type schema:CreativeWork
    649 https://doi.org/10.1056/nejmoa0901409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020263078
    650 rdf:type schema:CreativeWork
    651 https://doi.org/10.1073/pnas.0307323101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049808985
    652 rdf:type schema:CreativeWork
    653 https://doi.org/10.1073/pnas.0707351104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003925185
    654 rdf:type schema:CreativeWork
    655 https://doi.org/10.1073/pnas.1014720108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001498014
    656 rdf:type schema:CreativeWork
    657 https://doi.org/10.1073/pnas.1015541107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007992906
    658 rdf:type schema:CreativeWork
    659 https://doi.org/10.1073/pnas.242606799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025755034
    660 rdf:type schema:CreativeWork
    661 https://doi.org/10.1074/jbc.m109.027466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038031135
    662 rdf:type schema:CreativeWork
    663 https://doi.org/10.1074/jbc.m109.079525 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033622730
    664 rdf:type schema:CreativeWork
    665 https://doi.org/10.1074/jbc.m110.101055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025781556
    666 rdf:type schema:CreativeWork
    667 https://doi.org/10.1074/jbc.m110.216887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025062157
    668 rdf:type schema:CreativeWork
    669 https://doi.org/10.1074/jbc.m111.227611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000527084
    670 rdf:type schema:CreativeWork
    671 https://doi.org/10.1074/jbc.m111.265439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053003575
    672 rdf:type schema:CreativeWork
    673 https://doi.org/10.1074/jbc.m111.291229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039691610
    674 rdf:type schema:CreativeWork
    675 https://doi.org/10.1074/jbc.m111.307405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013248167
    676 rdf:type schema:CreativeWork
    677 https://doi.org/10.1074/jbc.m112.408104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010399155
    678 rdf:type schema:CreativeWork
    679 https://doi.org/10.1074/jbc.m112.434340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030067633
    680 rdf:type schema:CreativeWork
    681 https://doi.org/10.1074/jbc.m114.598383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010707876
    682 rdf:type schema:CreativeWork
    683 https://doi.org/10.1074/jbc.m709382200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021086109
    684 rdf:type schema:CreativeWork
    685 https://doi.org/10.1074/jbc.m806041200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004856248
    686 rdf:type schema:CreativeWork
    687 https://doi.org/10.1093/abbs/gmq125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026524422
    688 rdf:type schema:CreativeWork
    689 https://doi.org/10.1093/abbs/gmr128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031367207
    690 rdf:type schema:CreativeWork
    691 https://doi.org/10.1093/abbs/gms026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036911491
    692 rdf:type schema:CreativeWork
    693 https://doi.org/10.1093/abbs/gms099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001906812
    694 rdf:type schema:CreativeWork
    695 https://doi.org/10.1093/abbs/gmt113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028333099
    696 rdf:type schema:CreativeWork
    697 https://doi.org/10.1093/carcin/bgp219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012261114
    698 rdf:type schema:CreativeWork
    699 https://doi.org/10.1093/carcin/bgq192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031939212
    700 rdf:type schema:CreativeWork
    701 https://doi.org/10.1093/jnci/djn123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003446650
    702 rdf:type schema:CreativeWork
    703 https://doi.org/10.1093/jnci/djt302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053220493
    704 rdf:type schema:CreativeWork
    705 https://doi.org/10.1093/nar/gkn522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012733286
    706 rdf:type schema:CreativeWork
    707 https://doi.org/10.1097/cad.0000000000000107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016722884
    708 rdf:type schema:CreativeWork
    709 https://doi.org/10.1111/febs.13012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008978352
    710 rdf:type schema:CreativeWork
    711 https://doi.org/10.1111/j.1365-2141.2008.07459.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019958546
    712 rdf:type schema:CreativeWork
    713 https://doi.org/10.1124/mol.108.054163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036978857
    714 rdf:type schema:CreativeWork
    715 https://doi.org/10.1124/mol.114.092759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021282371
    716 rdf:type schema:CreativeWork
    717 https://doi.org/10.1126/science.1149460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015783172
    718 rdf:type schema:CreativeWork
    719 https://doi.org/10.1128/mcb.00941-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045279634
    720 rdf:type schema:CreativeWork
    721 https://doi.org/10.1146/annurev.med.53.082901.103929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044382782
    722 rdf:type schema:CreativeWork
    723 https://doi.org/10.1155/2010/821717 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009629786
    724 rdf:type schema:CreativeWork
    725 https://doi.org/10.1158/0008-5472.can-05-2352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030953088
    726 rdf:type schema:CreativeWork
    727 https://doi.org/10.1158/0008-5472.can-06-1403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016407635
    728 rdf:type schema:CreativeWork
    729 https://doi.org/10.1158/0008-5472.can-06-2698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031596158
    730 rdf:type schema:CreativeWork
    731 https://doi.org/10.1158/0008-5472.can-07-2488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008557928
    732 rdf:type schema:CreativeWork
    733 https://doi.org/10.1158/0008-5472.can-10-0145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050520970
    734 rdf:type schema:CreativeWork
    735 https://doi.org/10.1158/0008-5472.can-12-0103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018428226
    736 rdf:type schema:CreativeWork
    737 https://doi.org/10.1158/0008-5472.can-12-3308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046698073
    738 rdf:type schema:CreativeWork
    739 https://doi.org/10.1158/0008-5472.can-14-1140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029802103
    740 rdf:type schema:CreativeWork
    741 https://doi.org/10.1158/1078-0432.ccr-13-2805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006902149
    742 rdf:type schema:CreativeWork
    743 https://doi.org/10.1158/1535-7163.mct-08-0021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000376245
    744 rdf:type schema:CreativeWork
    745 https://doi.org/10.1158/1535-7163.mct-08-1046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033400586
    746 rdf:type schema:CreativeWork
    747 https://doi.org/10.1158/1535-7163.mct-10-0397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028890591
    748 rdf:type schema:CreativeWork
    749 https://doi.org/10.1158/1535-7163.mct-12-0463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022470651
    750 rdf:type schema:CreativeWork
    751 https://doi.org/10.1158/1535-7163.mct-13-0448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009802116
    752 rdf:type schema:CreativeWork
    753 https://doi.org/10.1158/1535-7163.mct-14-0245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038901134
    754 rdf:type schema:CreativeWork
    755 https://doi.org/10.1158/2159-8290.cd-13-0202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021245915
    756 rdf:type schema:CreativeWork
    757 https://doi.org/10.1159/000354521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016201429
    758 rdf:type schema:CreativeWork
    759 https://doi.org/10.1159/000374036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048426237
    760 rdf:type schema:CreativeWork
    761 https://doi.org/10.1172/jci43897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053570320
    762 rdf:type schema:CreativeWork
    763 https://doi.org/10.1177/1010428317703825 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086105010
    764 rdf:type schema:CreativeWork
    765 https://doi.org/10.1177/1535370213497321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031929364
    766 rdf:type schema:CreativeWork
    767 https://doi.org/10.1177/1947601911425832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064081109
    768 rdf:type schema:CreativeWork
    769 https://doi.org/10.1182/blood-2009-09-243147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013451101
    770 rdf:type schema:CreativeWork
    771 https://doi.org/10.1182/blood-2014-06-581926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014465716
    772 rdf:type schema:CreativeWork
    773 https://doi.org/10.1200/jco.2009.24.0317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051779030
    774 rdf:type schema:CreativeWork
    775 https://doi.org/10.1371/journal.pone.0028308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052468320
    776 rdf:type schema:CreativeWork
    777 https://doi.org/10.1371/journal.pone.0030560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028864983
    778 rdf:type schema:CreativeWork
    779 https://doi.org/10.1371/journal.pone.0034210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005998839
    780 rdf:type schema:CreativeWork
    781 https://doi.org/10.1371/journal.pone.0039167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017755652
    782 rdf:type schema:CreativeWork
    783 https://doi.org/10.1371/journal.pone.0039197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005664674
    784 rdf:type schema:CreativeWork
    785 https://doi.org/10.1371/journal.pone.0050469 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008684442
    786 rdf:type schema:CreativeWork
    787 https://doi.org/10.1371/journal.pone.0058169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010554391
    788 rdf:type schema:CreativeWork
    789 https://doi.org/10.1371/journal.pone.0059390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006869353
    790 rdf:type schema:CreativeWork
    791 https://doi.org/10.1371/journal.pone.0061858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007153582
    792 rdf:type schema:CreativeWork
    793 https://doi.org/10.1371/journal.pone.0062334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037217396
    794 rdf:type schema:CreativeWork
    795 https://doi.org/10.1371/journal.pone.0072615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045268115
    796 rdf:type schema:CreativeWork
    797 https://doi.org/10.1371/journal.pone.0089446 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027755941
    798 rdf:type schema:CreativeWork
    799 https://doi.org/10.1371/journal.pone.0095716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014146485
    800 rdf:type schema:CreativeWork
    801 https://doi.org/10.1371/journal.pone.0115565 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013173330
    802 rdf:type schema:CreativeWork
    803 https://doi.org/10.1590/1414-431x20133324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038184017
    804 rdf:type schema:CreativeWork
    805 https://doi.org/10.18632/oncotarget.1202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008828006
    806 rdf:type schema:CreativeWork
    807 https://doi.org/10.18632/oncotarget.1458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009339461
    808 rdf:type schema:CreativeWork
    809 https://doi.org/10.18632/oncotarget.15559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083868131
    810 rdf:type schema:CreativeWork
    811 https://doi.org/10.18632/oncotarget.15781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084372899
    812 rdf:type schema:CreativeWork
    813 https://doi.org/10.18632/oncotarget.2594 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012176508
    814 rdf:type schema:CreativeWork
    815 https://doi.org/10.18632/oncotarget.3563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019451721
    816 rdf:type schema:CreativeWork
    817 https://doi.org/10.2174/1389200216666151015113400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069176464
    818 rdf:type schema:CreativeWork
    819 https://doi.org/10.2174/138920371604150429154142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069179673
    820 rdf:type schema:CreativeWork
    821 https://doi.org/10.2174/1389450116666150325231419 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069181477
    822 rdf:type schema:CreativeWork
    823 https://doi.org/10.2217/epi.10.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024643483
    824 rdf:type schema:CreativeWork
    825 https://doi.org/10.3109/01902148.2011.584263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036263825
    826 rdf:type schema:CreativeWork
    827 https://doi.org/10.3109/07853890.2015.1043140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034352770
    828 rdf:type schema:CreativeWork
    829 https://doi.org/10.3109/1061186x.2015.1015536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001692102
    830 rdf:type schema:CreativeWork
    831 https://doi.org/10.3322/caac.20073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042069193
    832 rdf:type schema:CreativeWork
    833 https://doi.org/10.3322/caac.21254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011682275
    834 rdf:type schema:CreativeWork
    835 https://doi.org/10.3390/ijms14010480 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037887889
    836 rdf:type schema:CreativeWork
    837 https://doi.org/10.3892/ijmm.2013.1439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071507661
    838 rdf:type schema:CreativeWork
    839 https://doi.org/10.3892/ijo.2012.1418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071512751
    840 rdf:type schema:CreativeWork
    841 https://doi.org/10.3892/mmr.2012.776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032259727
    842 rdf:type schema:CreativeWork
    843 https://doi.org/10.3892/mmr.2014.2271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071521769
    844 rdf:type schema:CreativeWork
    845 https://doi.org/10.3892/mmr.2014.2688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071522086
    846 rdf:type schema:CreativeWork
    847 https://doi.org/10.3892/ol.2013.1644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044207073
    848 rdf:type schema:CreativeWork
    849 https://doi.org/10.3892/ol.2017.6982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091856074
    850 rdf:type schema:CreativeWork
    851 https://doi.org/10.3892/or.2011.1472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071531585
    852 rdf:type schema:CreativeWork
    853 https://doi.org/10.3892/or.2012.1823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071531879
    854 rdf:type schema:CreativeWork
    855 https://doi.org/10.3892/or.2013.2532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071532495
    856 rdf:type schema:CreativeWork
    857 https://doi.org/10.3892/or.2013.2755 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071532694
    858 rdf:type schema:CreativeWork
    859 https://doi.org/10.3892/or.2013.2897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071532818
    860 rdf:type schema:CreativeWork
    861 https://doi.org/10.3892/or.2014.3646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071533461
    862 rdf:type schema:CreativeWork
    863 https://doi.org/10.4161/cc.21503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048786567
    864 rdf:type schema:CreativeWork
    865 https://doi.org/10.4161/cc.7.16.6533 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072299587
    866 rdf:type schema:CreativeWork
    867 https://doi.org/10.5483/bmbrep.2014.47.5.165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024463545
    868 rdf:type schema:CreativeWork
    869 https://doi.org/10.7314/apjcp.2013.14.12.7529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022412156
    870 rdf:type schema:CreativeWork
    871 https://doi.org/10.7314/apjcp.2014.15.13.5137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024416336
    872 rdf:type schema:CreativeWork
    873 https://doi.org/10.7314/apjcp.2014.15.23.10439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045715624
    874 rdf:type schema:CreativeWork
    875 https://doi.org/10.7785/tcrt.2012.500364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074053007
    876 rdf:type schema:CreativeWork
    877 https://www.grid.ac/institutes/grid.13402.34 schema:alternateName Zhejiang University
    878 schema:name Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    879 rdf:type schema:Organization
    880 https://www.grid.ac/institutes/grid.259828.c schema:alternateName Medical University of South Carolina
    881 schema:name Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 29425, Charleston, SC, USA
    882 Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China
    883 rdf:type schema:Organization
    884 https://www.grid.ac/institutes/grid.452661.2 schema:alternateName First Affiliated Hospital Zhejiang University
    885 schema:name Clinical Research Center, First Affiliated Hospital of Zhejiang University College of Medicine, 310000, Hangzhou, China
    886 Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China
    887 rdf:type schema:Organization
    888 https://www.grid.ac/institutes/grid.453135.5 schema:alternateName National Health and Family Planning Commission
    889 schema:name Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, 310000, Hangzhou, China
    890 Key Laboratory of Organ Transplantation, 310003, Hangzhou, Zhejiang Province, China
    891 Program of Innovative Cancer Therapeutics, Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, China
    892 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...