Ontology type: schema:ScholarlyArticle Open Access: True
2022-04-14
AUTHORSRandima Dasanayake, Thivya Balendran, Dhilma Atapattu, Devika Iddawela
ABSTRACTObjectivesCanine dirofilariasis is a mosquito borne zoonotic filarial parasitic disease caused by Dirofilaria species. In Sri Lanka, human dirofilariasis is endemic and well documented. Even though canine dirofilariasis is an established infection among dog populations in Sri Lanka, the prevalence and risk factors were not documented in Kanthale divisional secretariat, Eastern Province of Sri Lanka. Therefore, the main objective of this study is to determine the prevalence of dirofilariasis and to identify the exposure-related risk factors in dogs using an interviewer administered questionnaire in Kanthale divisional secretariat.ResultsOut of 162 blood samples collected from dogs, 47.5% (n = 77/162) were positive for the presence of microfilariae by direct smear. Of 162 samples 58.6% (n = 95/162) were molecularly identified as D. repens. Species-specific primer pair DIR3/DIR4 that amplified 5S rRNA was used. The current study observed a significant association between mongrels and canine dirofilariasis (p = 0.049), where 61.3% (n = 95) out of 155 mongrels showed PCR positivity. This study showed no significant association between the occurrence of dirofilariasis and the age, sex, rearing method, presence or absence of skin rash, and stray or domestic dogs. Dirofilaria immitis was not identified in direct smear test and PCR. More... »
PAGES137
http://scigraph.springernature.com/pub.10.1186/s13104-022-06024-0
DOIhttp://dx.doi.org/10.1186/s13104-022-06024-0
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/35421998
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