Seroprevalence of mumps before the introduction of mumps-containing vaccine in Lao PDR: results from a nationwide cross-sectional population-based survey View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Hironori Okabayashi, Kenichi Komada, Minoru Kidokoro, Tomomi Kitamura, Shinsuke Miyano, Tomoo Ito, Kongxay Phounphenghak, Chansay Pathammavong, Keiko Murano, Misato Nagai, Yoshio Mori, Katsuhiro Komase, Anonh Xeuatvongsa, Makoto Takeda, Masahiko Hachiya

ABSTRACT

OBJECTIVE: Mumps-containing vaccine is currently not a component of the national immunization schedule in Lao People's Democratic Republic (PDR). Mumps itself is not a notifiable disease in the country and the seroprevalence of anti-mumps immunoglobulin G (IgG) in the general population is unknown. In this study, anti-mumps IgG was measured in 2058 blood samples to evaluate population immunity in the country. RESULTS: The seroprevalence of anti-mumps IgG showed a gradual increase with increasing age, starting at 10.6% (95% CI 7.4-13.7) in participants aged 1-2 years, and almost plateaued at about 75% in individuals older than 11-12 years, though it still tended toward a small increase up to 89.6% (95% CI 86.6-92.6) in participants aged 40 years or older. Compared with the results of previous studies, this increase with increasing age is less marked and the plateau of anti-mumps seroprevalence is lower. We attribute this result mainly to the lower population density in Lao PDR. More... »

PAGES

155

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13104-019-4194-3

DOI

http://dx.doi.org/10.1186/s13104-019-4194-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112871656

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30890154


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