Measuring the health-related quality of life of children with impaired mobility: examining correlation and agreement between children and parent proxies View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-08-10

AUTHORS

Nathan Bray, Jane Noyes, Nigel Harris, Rhiannon Tudor Edwards

ABSTRACT

ObjectiveThe objective of this research project was to evaluate the validity of proxy health-related quality of life measures in the context of paediatric mobility impairment. Accurate health-related quality of life data is essential for quality-adjusted life year calculation; a key outcome in economic evaluation. Thirteen child-parent dyads (13 children with mobility impairments, 13 parent proxies) were asked to complete a range of outcome measures (EQ-5D-Y, VAS and HUI2/3) relating to the child’s health. The relationship between respondent outcomes was examined using tests of respondent type effect (Wilcoxon signed-rank), correlation (Spearman’s rank-order) and agreement (Bland–Altman plots).ResultsParent proxies significantly undervalued the health-related quality of life of their mobility-impaired children: children rated their health-related quality of life higher than their parents by proxy on all measures. The VAS had the highest overall mean score for children and proxies (79.50 [SD = 15.01] and 75.77 [SD = 14.70] respectively). Child and proxy results were significantly different (p < 0.05) for all measures besides the VAS (p = 0.138). Strong correlation and acceptable agreement were observed for equivalent child/proxy VAS and HUI measures. The EQ-5D-Y exhibited the least agreement between children and proxies. Sufficient association between child/proxy VAS and HUI measures indicated a degree of interchangeability. More... »

PAGES

377

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13104-017-2683-9

DOI

http://dx.doi.org/10.1186/s13104-017-2683-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091143755

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28797288


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