Ontology type: schema:ScholarlyArticle Open Access: True
2018-01-11
AUTHORSYumiko Sugiyama, Ryusuke Yoshimi, Maasa Tamura, Mitsuhiro Takeno, Yosuke Kunishita, Daiga Kishimoto, Yuji Yoshioka, Kouji Kobayashi, Kaoru Takase-Minegishi, Toshiyuki Watanabe, Naoki Hamada, Hideto Nagai, Naomi Tsuchida, Yutaro Soejima, Hiroto Nakano, Reikou Kamiyama, Takeaki Uehara, Yohei Kirino, Akiko Sekiguchi, Atsushi Ihata, Shigeru Ohno, Shouhei Nagaoka, Hideaki Nakajima
ABSTRACTBackgroundInterstitial lung disease (ILD) is the principal cause of death in polymyositis/dermatomyositis (PM/DM). Here we investigated prognostic factors for death and serious infection in PM/DM-ILD using the multicenter database.MethodsWe retrospectively reviewed baseline demographic, clinical and laboratory findings, treatment regimens and outcomes in patients with PM/DM-ILD. The distribution of ILD lesions was evaluated in four divided lung zones of high-resolution computed tomography images.ResultsOf 116 patients with PM/DM-ILD, 14 died within 6 months from the diagnosis. As independent risk factors for early death, extended ILD lesions in upper lung fields (odds ratio (OR) 8.01, p = 0.016) and hypocapnia (OR 6.85, p = 0.038) were identified. Serious infection was found in 38 patients, including 11 patients who died of respiratory or multiple infections. The independent risk factors were high serum KL-6 (OR 3.68, p = 0.027), high initial dose of prednisolone (PSL) (OR 4.18, p = 0.013), and combination immunosuppressive therapies (OR 5.51, p < 0.001).ConclusionThe present study shows the progression of ILD at baseline is the most critical for survival and that infection, especially respiratory infection, is an additive prognostic factor under the potent immunosuppressive treatment. More... »
PAGES7
http://scigraph.springernature.com/pub.10.1186/s13075-017-1506-7
DOIhttp://dx.doi.org/10.1186/s13075-017-1506-7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1100316079
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29325580
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Cardiorespiratory Medicine and Haematology",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Anti-Inflammatory Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Dermatomyositis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Progression",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunosuppressive Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung Diseases, Interstitial",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Polymyositis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prednisolone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prognosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tomography, X-Ray Computed",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Sugiyama",
"givenName": "Yumiko",
"id": "sg:person.013674701415.55",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013674701415.55"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Yoshimi",
"givenName": "Ryusuke",
"id": "sg:person.01207257733.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207257733.06"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Tamura",
"givenName": "Maasa",
"id": "sg:person.012725501351.84",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012725501351.84"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan",
"id": "http://www.grid.ac/institutes/grid.410821.e",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan"
],
"type": "Organization"
},
"familyName": "Takeno",
"givenName": "Mitsuhiro",
"id": "sg:person.01027461256.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027461256.90"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Kunishita",
"givenName": "Yosuke",
"id": "sg:person.01017341335.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017341335.17"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Kishimoto",
"givenName": "Daiga",
"id": "sg:person.01053764557.34",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053764557.34"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Yokohama Minami Kyosai Hospital, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.417365.2",
"name": [
"Yokohama Minami Kyosai Hospital, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Yoshioka",
"givenName": "Yuji",
"id": "sg:person.012572556414.81",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012572556414.81"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.413045.7",
"name": [
"Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Kobayashi",
"givenName": "Kouji",
"id": "sg:person.010023606204.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010023606204.54"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.413045.7",
"name": [
"Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Takase-Minegishi",
"givenName": "Kaoru",
"id": "sg:person.01260020137.32",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260020137.32"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National Hospital Organization Yokohama Medical Center, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.416698.4",
"name": [
"National Hospital Organization Yokohama Medical Center, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Watanabe",
"givenName": "Toshiyuki",
"id": "sg:person.0723327632.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723327632.90"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Hamada",
"givenName": "Naoki",
"id": "sg:person.012642523373.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012642523373.40"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Nagai",
"givenName": "Hideto",
"id": "sg:person.010006042424.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010006042424.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Tsuchida",
"givenName": "Naomi",
"id": "sg:person.010452633515.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010452633515.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Soejima",
"givenName": "Yutaro",
"id": "sg:person.015033044773.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015033044773.50"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Nakano",
"givenName": "Hiroto",
"id": "sg:person.010335136176.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010335136176.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Kamiyama",
"givenName": "Reikou",
"id": "sg:person.0771443032.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771443032.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Chigasaki Municipal Hospital, Chigasaki, Japan",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Chigasaki Municipal Hospital, Chigasaki, Japan"
],
"type": "Organization"
},
"familyName": "Uehara",
"givenName": "Takeaki",
"id": "sg:person.01077164063.38",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077164063.38"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Kirino",
"givenName": "Yohei",
"id": "sg:person.01205656516.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205656516.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Fujisawa City Hospital, Fujisawa, Japan",
"id": "http://www.grid.ac/institutes/grid.415120.3",
"name": [
"Fujisawa City Hospital, Fujisawa, Japan"
],
"type": "Organization"
},
"familyName": "Sekiguchi",
"givenName": "Akiko",
"id": "sg:person.014303334637.11",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014303334637.11"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "National Hospital Organization Yokohama Medical Center, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.416698.4",
"name": [
"National Hospital Organization Yokohama Medical Center, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Ihata",
"givenName": "Atsushi",
"id": "sg:person.01364010267.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364010267.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.413045.7",
"name": [
"Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Ohno",
"givenName": "Shigeru",
"id": "sg:person.013722512012.55",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013722512012.55"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Yokohama Minami Kyosai Hospital, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.417365.2",
"name": [
"Yokohama Minami Kyosai Hospital, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Nagaoka",
"givenName": "Shouhei",
"id": "sg:person.014057134732.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014057134732.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan",
"id": "http://www.grid.ac/institutes/grid.268441.d",
"name": [
"Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-ku, Yokohama, Japan"
],
"type": "Organization"
},
"familyName": "Nakajima",
"givenName": "Hideaki",
"id": "sg:person.010061552415.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010061552415.35"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00296-011-2323-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004117733",
"https://doi.org/10.1007/s00296-011-2323-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10067-016-3296-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020437845",
"https://doi.org/10.1007/s10067-016-3296-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11926-012-0246-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050281863",
"https://doi.org/10.1007/s11926-012-0246-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11926-012-0249-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016486166",
"https://doi.org/10.1007/s11926-012-0249-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10067-011-1840-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012048567",
"https://doi.org/10.1007/s10067-011-1840-0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/ar3704",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003395918",
"https://doi.org/10.1186/ar3704"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-01-11",
"datePublishedReg": "2018-01-11",
"description": "BackgroundInterstitial lung disease (ILD) is the principal cause of death in polymyositis/dermatomyositis (PM/DM). Here we investigated prognostic factors for death and serious infection in PM/DM-ILD using the multicenter database.MethodsWe retrospectively reviewed baseline demographic, clinical and laboratory findings, treatment regimens and outcomes in patients with PM/DM-ILD. The distribution of ILD lesions was evaluated in four divided lung zones of high-resolution computed tomography images.ResultsOf 116 patients with PM/DM-ILD, 14 died within 6\u00a0months from the diagnosis. As independent risk factors for early death, extended ILD lesions in upper lung fields (odds ratio (OR) 8.01, p\u2009=\u20090.016) and hypocapnia (OR 6.85, p\u2009=\u20090.038) were identified. Serious infection was found in 38 patients, including 11 patients who died of\u00a0respiratory or multiple infections. The independent risk factors were high serum KL-6 (OR 3.68, p\u2009=\u20090.027), high initial dose of prednisolone (PSL) (OR 4.18, p\u2009=\u20090.013), and combination immunosuppressive therapies (OR 5.51, p\u2009<\u20090.001).ConclusionThe present study shows the progression of ILD at baseline is the most critical for survival and that infection, especially respiratory infection, is an additive prognostic factor under the potent immunosuppressive treatment.",
"genre": "article",
"id": "sg:pub.10.1186/s13075-017-1506-7",
"inLanguage": "en",
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.5870677",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.6150551",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1297499",
"issn": [
"1478-6354",
"1478-6362"
],
"name": "Arthritis Research & Therapy",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "20"
}
],
"keywords": [
"PM/DM-ILD",
"independent risk factor",
"DM-ILD",
"prognostic factors",
"lung disease",
"serious infections",
"risk factors",
"polymyositis/dermatomyositis-associated interstitial lung disease",
"dermatomyositis-associated interstitial lung disease",
"BackgroundInterstitial lung disease",
"ResultsOf 116 patients",
"combination immunosuppressive therapy",
"progression of ILD",
"potent immunosuppressive treatment",
"upper lung field",
"high serum KL-6",
"polymyositis/dermatomyositis",
"serum KL-6",
"predictive prognostic factors",
"interstitial lung disease",
"higher initial dose",
"ConclusionThe present study",
"immunosuppressive treatment",
"KL-6",
"immunosuppressive therapy",
"respiratory infections",
"multicenter database",
"treatment regimens",
"lung zones",
"initial dose",
"laboratory findings",
"lung fields",
"early death",
"patients",
"multiple infections",
"infection",
"prednisolone",
"death",
"lesions",
"disease",
"principal cause",
"baseline",
"tomography images",
"present study",
"dermatomyositis",
"regimens",
"factors",
"hypocapnia",
"therapy",
"MethodsWe",
"diagnosis",
"dose",
"progression",
"months",
"survival",
"ILD",
"outcomes",
"treatment",
"cause",
"findings",
"database",
"study",
"images",
"distribution",
"zone",
"field"
],
"name": "The predictive prognostic factors for polymyositis/dermatomyositis-associated interstitial lung disease",
"pagination": "7",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1100316079"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13075-017-1506-7"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29325580"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13075-017-1506-7",
"https://app.dimensions.ai/details/publication/pub.1100316079"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:35",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_779.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1186/s13075-017-1506-7"
}
]Download the RDF metadata as:Â json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13075-017-1506-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13075-017-1506-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13075-017-1506-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13075-017-1506-7'
This table displays all metadata directly associated to this object as RDF triples.
401 TRIPLES
22 PREDICATES
116 URIs
102 LITERALS
25 BLANK NODES