Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSSusan Högg, Manfred Holzgraefe, Insa Wingendorf, Jan Mehrholz, Christoph Herrmann, Mark Obermann
ABSTRACTBACKGROUND: Stroke patients are often affected by arm paresis, have functional impairments and receive help from professional or informal caregivers. Progressive resistance training is a common intervention for functional impairments after paresis. Randomised controlled trials (RCT) showed benefits for functional recovery after resistance training. However, there is a lack of evidence for strength training in subacute stroke patients. The aim of this study is to investigate safety and effectiveness of arm strength training in subacute stroke patients. METHODS: We will conduct a prospective, assessor-blinded RCT of people with subacute stroke. We will randomly assign patients to one of two parallel groups in a 1:1 ratio and will use concealed allocation. The intervention group will receive, in addition to standard treatment, high-intensity arm training (three times per week, over three weeks; 60 min each session; with a total of nine additional sessions). The control group will receive, in addition to standard treatment, low-intensity arm training (same quantity, frequency and treatment time as the intervention group). Standard treatment for the affected arm includes mobilisation, stretching, therapeutic positioning, arm and hand motor training, strengthening exercises, mechanical assisted training, functional training and task-oriented training. The primary efficacy endpoint will be grip strength. Secondary outcome measures will be Modified Ashworth Scale, Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test and Goal Attainment Scale for individual participatory goals. We will measure primary and secondary outcomes with blinded assessors at baseline and immediately after three weeks of additional therapy. Based on our sample size calculation, 78 patients will be recruited from our rehabilitation hospital in two and a half years. Drop-out rates and adverse events will be systematically recorded. DISCUSSION: This study attempts to close the evidence gap for effects of arm strength training in subacute stroke patients. The results of this trial will provide robust evidence for effects and safety of high-intensity arm training for people with stroke. TRIAL REGISTRATION: German Clinical Trials Register, DRKS00012484 . Registered on 26 May 2017. More... »
PAGES168
http://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3
DOIhttp://dx.doi.org/10.1186/s13063-019-3261-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1112781788
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30876438
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Asklepios Kliniken Schildautal",
"id": "https://www.grid.ac/institutes/grid.491814.1",
"name": [
"Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation und Klinik f\u00fcr Neurologische Fr\u00fchrehabilitation, Physiotherapie, Seesen, Germany"
],
"type": "Organization"
},
"familyName": "H\u00f6gg",
"givenName": "Susan",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Asklepios Kliniken Schildautal",
"id": "https://www.grid.ac/institutes/grid.491814.1",
"name": [
"Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation, Seesen, Germany"
],
"type": "Organization"
},
"familyName": "Holzgraefe",
"givenName": "Manfred",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Asklepios Kliniken Schildautal",
"id": "https://www.grid.ac/institutes/grid.491814.1",
"name": [
"Asklepios Kliniken Schildautal, Physiotherapie, Seesen, Germany"
],
"type": "Organization"
},
"familyName": "Wingendorf",
"givenName": "Insa",
"type": "Person"
},
{
"affiliation": {
"alternateName": "TU Dresden",
"id": "https://www.grid.ac/institutes/grid.4488.0",
"name": [
"Department of Public Health, Dresden Medical School, Technical University Dresden, Dresden, Germany"
],
"type": "Organization"
},
"familyName": "Mehrholz",
"givenName": "Jan",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Asklepios Kliniken Schildautal",
"id": "https://www.grid.ac/institutes/grid.491814.1",
"name": [
"Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation, Seesen, Germany"
],
"type": "Organization"
},
"familyName": "Herrmann",
"givenName": "Christoph",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Asklepios Kliniken Schildautal",
"id": "https://www.grid.ac/institutes/grid.491814.1",
"name": [
"Asklepios Kliniken Schildautal, Zentrum f\u00fcr Neurologie, Seesen, Germany"
],
"type": "Organization"
},
"familyName": "Obermann",
"givenName": "Mark",
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/j.apmr.2008.02.022",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001889946"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968311433426",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005365152"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968311433426",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005365152"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.apmr.2003.06.027",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005998799"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mrr.0b013e32832a62ad",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006087514"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mrr.0b013e32832a62ad",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006087514"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0000000000001520",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006727002"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0000000000001520",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006727002"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0000000000001520",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006727002"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0000000000001520",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006727002"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/09638280600919764",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008083925"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.32.6.1279",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009854358"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/phm.0000000000000135",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012505247"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/phm.0000000000000135",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012505247"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/hjh.0b013e3281fc975a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012616091"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/hjh.0b013e3281fc975a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012616091"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12883-015-0292-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013456667",
"https://doi.org/10.1186/s12883-015-0292-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12883-015-0292-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013456667",
"https://doi.org/10.1186/s12883-015-0292-6"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.phm.0000137313.14480.ce",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015535664"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.phm.0000137313.14480.ce",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015535664"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/str.0000000000000024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021520827"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/str.0000000000000024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021520827"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2012/298375",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024002787"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/apmr.2003.50110",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025220434"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2522/ptj.20080285",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025336179"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.72.4.473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029302734"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0131048",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030183678"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968314535985",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032951333"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968314535985",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032951333"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0895-4356(88)90084-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042123582"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/apmr.2002.35089",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042349130"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002060-200212000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043511311"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00002060-200212000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043511311"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.48.1.7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043691363"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(98)09477-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043776499"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/14651858.cd010820.pub2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043896497"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.apmr.2005.08.113",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043911380"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0b013e3181d32e29",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044565021"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1519/jsc.0b013e3181d32e29",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044565021"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1745-6215-15-322",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044694346",
"https://doi.org/10.1186/1745-6215-15-322"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.0000143153.76460.7d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044865502"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.0000143153.76460.7d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044865502"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000421-198212000-00014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045278392"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000421-198212000-00014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045278392"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2016/9346374",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047314887"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.52.11.1267",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048503202"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/10749357.2016.1138672",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048645127"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-9993(91)90010-g",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054541205"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-9993(91)90010-g",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054541205"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269215508101741",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063798827"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269215508101741",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063798827"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968308326635",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064059125"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1545968308326635",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064059125"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1191/0269215504cr843oa",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064150136"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1191/0269215504cr843oa",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064150136"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064346564"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064346564"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064346564"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2340/16501977-2183",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070754163"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.7326/0003-4819-158-3-201302050-00583",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1073713447"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077619384",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078802651",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ptj/69.11.990",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1079406171"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080703684",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/17483107.2018.1449019",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1101499257"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-12",
"datePublishedReg": "2019-12-01",
"description": "BACKGROUND: Stroke patients are often affected by arm paresis, have functional impairments and receive help from professional or informal caregivers. Progressive resistance training is a common intervention for functional impairments after paresis. Randomised controlled trials (RCT) showed benefits for functional recovery after resistance training. However, there is a lack of evidence for strength training in subacute stroke patients. The aim of this study is to investigate safety and effectiveness of arm strength training in subacute stroke patients.\nMETHODS: We will conduct a prospective, assessor-blinded RCT of people with subacute stroke. We will randomly assign patients to one of two parallel groups in a 1:1 ratio and will use concealed allocation. The intervention group will receive, in addition to standard treatment, high-intensity arm training (three times per week, over three\u2009weeks; 60\u2009min each session; with a total of nine additional sessions). The control group will receive, in addition to standard treatment, low-intensity arm training (same quantity, frequency and treatment time as the intervention group). Standard treatment for the affected arm includes mobilisation, stretching, therapeutic positioning, arm and hand motor training, strengthening exercises, mechanical assisted training, functional training and task-oriented training. The primary efficacy endpoint will be grip strength. Secondary outcome measures will be Modified Ashworth Scale, Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test and Goal Attainment Scale for individual participatory goals. We will measure primary and secondary outcomes with blinded assessors at baseline and immediately after three\u2009weeks of additional therapy. Based on our sample size calculation, 78 patients will be recruited from our rehabilitation hospital in two and a half years. Drop-out rates and adverse events will be systematically recorded.\nDISCUSSION: This study attempts to close the evidence gap for effects of arm strength training in subacute stroke patients. The results of this trial will provide robust evidence for effects and safety of high-intensity arm training for people with stroke.\nTRIAL REGISTRATION: German Clinical Trials Register, DRKS00012484 . Registered on 26 May 2017.",
"genre": "research_article",
"id": "sg:pub.10.1186/s13063-019-3261-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1297400",
"issn": [
"1468-6708",
"1745-6215"
],
"name": "Trials",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "20"
}
],
"name": "Upper limb strength training in subacute stroke patients: study protocol of a randomised controlled trial",
"pagination": "168",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"fe4ee60396f05bcafe58d0b24fcf0c3900675a6a7a54fbc0f4dfebb265db6b6f"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30876438"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101263253"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13063-019-3261-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1112781788"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13063-019-3261-3",
"https://app.dimensions.ai/details/publication/pub.1112781788"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T13:19",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78953_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1186%2Fs13063-019-3261-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'
This table displays all metadata directly associated to this object as RDF triples.
235 TRIPLES
21 PREDICATES
73 URIs
21 LITERALS
9 BLANK NODES