Upper limb strength training in subacute stroke patients: study protocol of a randomised controlled trial View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Susan Högg, Manfred Holzgraefe, Insa Wingendorf, Jan Mehrholz, Christoph Herrmann, Mark Obermann

ABSTRACT

BACKGROUND: Stroke patients are often affected by arm paresis, have functional impairments and receive help from professional or informal caregivers. Progressive resistance training is a common intervention for functional impairments after paresis. Randomised controlled trials (RCT) showed benefits for functional recovery after resistance training. However, there is a lack of evidence for strength training in subacute stroke patients. The aim of this study is to investigate safety and effectiveness of arm strength training in subacute stroke patients. METHODS: We will conduct a prospective, assessor-blinded RCT of people with subacute stroke. We will randomly assign patients to one of two parallel groups in a 1:1 ratio and will use concealed allocation. The intervention group will receive, in addition to standard treatment, high-intensity arm training (three times per week, over three weeks; 60 min each session; with a total of nine additional sessions). The control group will receive, in addition to standard treatment, low-intensity arm training (same quantity, frequency and treatment time as the intervention group). Standard treatment for the affected arm includes mobilisation, stretching, therapeutic positioning, arm and hand motor training, strengthening exercises, mechanical assisted training, functional training and task-oriented training. The primary efficacy endpoint will be grip strength. Secondary outcome measures will be Modified Ashworth Scale, Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test and Goal Attainment Scale for individual participatory goals. We will measure primary and secondary outcomes with blinded assessors at baseline and immediately after three weeks of additional therapy. Based on our sample size calculation, 78 patients will be recruited from our rehabilitation hospital in two and a half years. Drop-out rates and adverse events will be systematically recorded. DISCUSSION: This study attempts to close the evidence gap for effects of arm strength training in subacute stroke patients. The results of this trial will provide robust evidence for effects and safety of high-intensity arm training for people with stroke. TRIAL REGISTRATION: German Clinical Trials Register, DRKS00012484 . Registered on 26 May 2017. More... »

PAGES

168

Journal

TITLE

Trials

ISSUE

1

VOLUME

20

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3

DOI

http://dx.doi.org/10.1186/s13063-019-3261-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112781788

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30876438


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Asklepios Kliniken Schildautal", 
          "id": "https://www.grid.ac/institutes/grid.491814.1", 
          "name": [
            "Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation und Klinik f\u00fcr Neurologische Fr\u00fchrehabilitation, Physiotherapie, Seesen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "H\u00f6gg", 
        "givenName": "Susan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Asklepios Kliniken Schildautal", 
          "id": "https://www.grid.ac/institutes/grid.491814.1", 
          "name": [
            "Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation, Seesen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Holzgraefe", 
        "givenName": "Manfred", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Asklepios Kliniken Schildautal", 
          "id": "https://www.grid.ac/institutes/grid.491814.1", 
          "name": [
            "Asklepios Kliniken Schildautal, Physiotherapie, Seesen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wingendorf", 
        "givenName": "Insa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "Department of Public Health, Dresden Medical School, Technical University Dresden, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mehrholz", 
        "givenName": "Jan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Asklepios Kliniken Schildautal", 
          "id": "https://www.grid.ac/institutes/grid.491814.1", 
          "name": [
            "Asklepios Kliniken Schildautal, Klinik f\u00fcr Neurologische Rehabilitation, Seesen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herrmann", 
        "givenName": "Christoph", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Asklepios Kliniken Schildautal", 
          "id": "https://www.grid.ac/institutes/grid.491814.1", 
          "name": [
            "Asklepios Kliniken Schildautal, Zentrum f\u00fcr Neurologie, Seesen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Obermann", 
        "givenName": "Mark", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.apmr.2008.02.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001889946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968311433426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005365152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968311433426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005365152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.apmr.2003.06.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005998799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mrr.0b013e32832a62ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006087514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mrr.0b013e32832a62ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006087514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0000000000001520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006727002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0000000000001520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006727002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0000000000001520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006727002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0000000000001520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006727002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09638280600919764", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008083925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.32.6.1279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009854358"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/phm.0000000000000135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012505247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/phm.0000000000000135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012505247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e3281fc975a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012616091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e3281fc975a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012616091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12883-015-0292-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013456667", 
          "https://doi.org/10.1186/s12883-015-0292-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12883-015-0292-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013456667", 
          "https://doi.org/10.1186/s12883-015-0292-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.phm.0000137313.14480.ce", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015535664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.phm.0000137313.14480.ce", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015535664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/str.0000000000000024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021520827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/str.0000000000000024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021520827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/298375", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024002787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/apmr.2003.50110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025220434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2522/ptj.20080285", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025336179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.72.4.473", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029302734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0131048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030183678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968314535985", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032951333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968314535985", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032951333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0895-4356(88)90084-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042123582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/apmr.2002.35089", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042349130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002060-200212000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043511311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002060-200212000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043511311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.48.1.7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043691363"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(98)09477-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043776499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd010820.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043896497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.apmr.2005.08.113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043911380"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0b013e3181d32e29", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044565021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0b013e3181d32e29", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044565021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1745-6215-15-322", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044694346", 
          "https://doi.org/10.1186/1745-6215-15-322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.0000143153.76460.7d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044865502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.0000143153.76460.7d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044865502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-198212000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045278392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-198212000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045278392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2016/9346374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047314887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jnnp.52.11.1267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048503202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10749357.2016.1138672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048645127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9993(91)90010-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054541205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9993(91)90010-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054541205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269215508101741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063798827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269215508101741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063798827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968308326635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064059125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1545968308326635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064059125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1191/0269215504cr843oa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064150136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1191/0269215504cr843oa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064150136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/01.wnl.0000145605.20476.07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064346564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2340/16501977-2183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070754163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-158-3-201302050-00583", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073713447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077619384", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078802651", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ptj/69.11.990", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079406171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080703684", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/17483107.2018.1449019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101499257"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Stroke patients are often affected by arm paresis, have functional impairments and receive help from professional or informal caregivers. Progressive resistance training is a common intervention for functional impairments after paresis. Randomised controlled trials (RCT) showed benefits for functional recovery after resistance training. However, there is a lack of evidence for strength training in subacute stroke patients. The aim of this study is to investigate safety and effectiveness of arm strength training in subacute stroke patients.\nMETHODS: We will conduct a prospective, assessor-blinded RCT of people with subacute stroke. We will randomly assign patients to one of two parallel groups in a 1:1 ratio and will use concealed allocation. The intervention group will receive, in addition to standard treatment, high-intensity arm training (three times per week, over three\u2009weeks; 60\u2009min each session; with a total of nine additional sessions). The control group will receive, in addition to standard treatment, low-intensity arm training (same quantity, frequency and treatment time as the intervention group). Standard treatment for the affected arm includes mobilisation, stretching, therapeutic positioning, arm and hand motor training, strengthening exercises, mechanical assisted training, functional training and task-oriented training. The primary efficacy endpoint will be grip strength. Secondary outcome measures will be Modified Ashworth Scale, Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test and Goal Attainment Scale for individual participatory goals. We will measure primary and secondary outcomes with blinded assessors at baseline and immediately after three\u2009weeks of additional therapy. Based on our sample size calculation, 78 patients will be recruited from our rehabilitation hospital in two and a half years. Drop-out rates and adverse events will be systematically recorded.\nDISCUSSION: This study attempts to close the evidence gap for effects of arm strength training in subacute stroke patients. The results of this trial will provide robust evidence for effects and safety of high-intensity arm training for people with stroke.\nTRIAL REGISTRATION: German Clinical Trials Register, DRKS00012484 . Registered on 26 May 2017.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s13063-019-3261-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1297400", 
        "issn": [
          "1468-6708", 
          "1745-6215"
        ], 
        "name": "Trials", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "20"
      }
    ], 
    "name": "Upper limb strength training in subacute stroke patients: study protocol of a randomised controlled trial", 
    "pagination": "168", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "fe4ee60396f05bcafe58d0b24fcf0c3900675a6a7a54fbc0f4dfebb265db6b6f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30876438"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101263253"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13063-019-3261-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112781788"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13063-019-3261-3", 
      "https://app.dimensions.ai/details/publication/pub.1112781788"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78953_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs13063-019-3261-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13063-019-3261-3'


 

This table displays all metadata directly associated to this object as RDF triples.

235 TRIPLES      21 PREDICATES      73 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13063-019-3261-3 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N562b4674da9b4460b0b3b14f07f98dd8
4 schema:citation sg:pub.10.1186/1745-6215-15-322
5 sg:pub.10.1186/s12883-015-0292-6
6 https://app.dimensions.ai/details/publication/pub.1077619384
7 https://app.dimensions.ai/details/publication/pub.1078802651
8 https://app.dimensions.ai/details/publication/pub.1080703684
9 https://doi.org/10.1002/14651858.cd010820.pub2
10 https://doi.org/10.1016/0003-9993(91)90010-g
11 https://doi.org/10.1016/0895-4356(88)90084-4
12 https://doi.org/10.1016/j.apmr.2003.06.027
13 https://doi.org/10.1016/j.apmr.2005.08.113
14 https://doi.org/10.1016/j.apmr.2008.02.022
15 https://doi.org/10.1016/s0140-6736(98)09477-x
16 https://doi.org/10.1053/apmr.2002.35089
17 https://doi.org/10.1053/apmr.2003.50110
18 https://doi.org/10.1080/09638280600919764
19 https://doi.org/10.1080/10749357.2016.1138672
20 https://doi.org/10.1080/17483107.2018.1449019
21 https://doi.org/10.1093/ptj/69.11.990
22 https://doi.org/10.1097/00000421-198212000-00014
23 https://doi.org/10.1097/00002060-200212000-00002
24 https://doi.org/10.1097/01.phm.0000137313.14480.ce
25 https://doi.org/10.1097/hjh.0b013e3281fc975a
26 https://doi.org/10.1097/mrr.0b013e32832a62ad
27 https://doi.org/10.1097/phm.0000000000000135
28 https://doi.org/10.1136/jnnp.48.1.7
29 https://doi.org/10.1136/jnnp.52.11.1267
30 https://doi.org/10.1136/jnnp.72.4.473
31 https://doi.org/10.1155/2012/298375
32 https://doi.org/10.1155/2016/9346374
33 https://doi.org/10.1161/01.str.0000143153.76460.7d
34 https://doi.org/10.1161/01.str.32.6.1279
35 https://doi.org/10.1161/str.0000000000000024
36 https://doi.org/10.1177/0269215508101741
37 https://doi.org/10.1177/1545968308326635
38 https://doi.org/10.1177/1545968311433426
39 https://doi.org/10.1177/1545968314535985
40 https://doi.org/10.1191/0269215504cr843oa
41 https://doi.org/10.1212/01.wnl.0000145605.20476.07
42 https://doi.org/10.1371/journal.pone.0131048
43 https://doi.org/10.1519/jsc.0000000000001520
44 https://doi.org/10.1519/jsc.0b013e3181d32e29
45 https://doi.org/10.2340/16501977-2183
46 https://doi.org/10.2522/ptj.20080285
47 https://doi.org/10.7326/0003-4819-158-3-201302050-00583
48 schema:datePublished 2019-12
49 schema:datePublishedReg 2019-12-01
50 schema:description BACKGROUND: Stroke patients are often affected by arm paresis, have functional impairments and receive help from professional or informal caregivers. Progressive resistance training is a common intervention for functional impairments after paresis. Randomised controlled trials (RCT) showed benefits for functional recovery after resistance training. However, there is a lack of evidence for strength training in subacute stroke patients. The aim of this study is to investigate safety and effectiveness of arm strength training in subacute stroke patients. METHODS: We will conduct a prospective, assessor-blinded RCT of people with subacute stroke. We will randomly assign patients to one of two parallel groups in a 1:1 ratio and will use concealed allocation. The intervention group will receive, in addition to standard treatment, high-intensity arm training (three times per week, over three weeks; 60 min each session; with a total of nine additional sessions). The control group will receive, in addition to standard treatment, low-intensity arm training (same quantity, frequency and treatment time as the intervention group). Standard treatment for the affected arm includes mobilisation, stretching, therapeutic positioning, arm and hand motor training, strengthening exercises, mechanical assisted training, functional training and task-oriented training. The primary efficacy endpoint will be grip strength. Secondary outcome measures will be Modified Ashworth Scale, Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test and Goal Attainment Scale for individual participatory goals. We will measure primary and secondary outcomes with blinded assessors at baseline and immediately after three weeks of additional therapy. Based on our sample size calculation, 78 patients will be recruited from our rehabilitation hospital in two and a half years. Drop-out rates and adverse events will be systematically recorded. DISCUSSION: This study attempts to close the evidence gap for effects of arm strength training in subacute stroke patients. The results of this trial will provide robust evidence for effects and safety of high-intensity arm training for people with stroke. TRIAL REGISTRATION: German Clinical Trials Register, DRKS00012484 . Registered on 26 May 2017.
51 schema:genre research_article
52 schema:inLanguage en
53 schema:isAccessibleForFree true
54 schema:isPartOf N2d902775be2447f1b181488d3ed3dca3
55 N61bb6b9736c440339de14ecbf915ea8f
56 sg:journal.1297400
57 schema:name Upper limb strength training in subacute stroke patients: study protocol of a randomised controlled trial
58 schema:pagination 168
59 schema:productId N17eff89f59374fd585116d81fee1f438
60 N3ccd8de1641f4d5dbc8e6f4c4e197ffd
61 N94d2729957af464f8f89d219ac68aa01
62 Nb0be8d8998c24db186bcf8f35bc25096
63 Ne32d68b252784d3f9149fc4b5120f54f
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112781788
65 https://doi.org/10.1186/s13063-019-3261-3
66 schema:sdDatePublished 2019-04-11T13:19
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher Nda1f00e4c4154f0bbcbd82fd6da1a4c5
69 schema:url https://link.springer.com/10.1186%2Fs13063-019-3261-3
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N17eff89f59374fd585116d81fee1f438 schema:name dimensions_id
74 schema:value pub.1112781788
75 rdf:type schema:PropertyValue
76 N2d902775be2447f1b181488d3ed3dca3 schema:volumeNumber 20
77 rdf:type schema:PublicationVolume
78 N3ccd8de1641f4d5dbc8e6f4c4e197ffd schema:name pubmed_id
79 schema:value 30876438
80 rdf:type schema:PropertyValue
81 N4291b1b7fed744da8389812e0a5a42c6 schema:affiliation https://www.grid.ac/institutes/grid.491814.1
82 schema:familyName Herrmann
83 schema:givenName Christoph
84 rdf:type schema:Person
85 N4dcfc841bcc943a6b81057cf7e51492a rdf:first N4f182bf39e0b4ed7944ba7dd263b8972
86 rdf:rest Nf7f3242554e64c249e955c497b1f236f
87 N4f182bf39e0b4ed7944ba7dd263b8972 schema:affiliation https://www.grid.ac/institutes/grid.491814.1
88 schema:familyName Holzgraefe
89 schema:givenName Manfred
90 rdf:type schema:Person
91 N52f100547b1f459b88ae4caaa41c7986 rdf:first N4291b1b7fed744da8389812e0a5a42c6
92 rdf:rest N813fdf6ea04e4d3ca9f371b8b77dec66
93 N562b4674da9b4460b0b3b14f07f98dd8 rdf:first N818c5bcb654b41f68f06ff8da597875f
94 rdf:rest N4dcfc841bcc943a6b81057cf7e51492a
95 N5ec39c14a4cb46239430bf3663a7efa4 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
96 schema:familyName Mehrholz
97 schema:givenName Jan
98 rdf:type schema:Person
99 N61bb6b9736c440339de14ecbf915ea8f schema:issueNumber 1
100 rdf:type schema:PublicationIssue
101 N813fdf6ea04e4d3ca9f371b8b77dec66 rdf:first Ne644debe1d4b4e748992ffa4e9856764
102 rdf:rest rdf:nil
103 N818c5bcb654b41f68f06ff8da597875f schema:affiliation https://www.grid.ac/institutes/grid.491814.1
104 schema:familyName Högg
105 schema:givenName Susan
106 rdf:type schema:Person
107 N94d2729957af464f8f89d219ac68aa01 schema:name doi
108 schema:value 10.1186/s13063-019-3261-3
109 rdf:type schema:PropertyValue
110 Nb0be8d8998c24db186bcf8f35bc25096 schema:name readcube_id
111 schema:value fe4ee60396f05bcafe58d0b24fcf0c3900675a6a7a54fbc0f4dfebb265db6b6f
112 rdf:type schema:PropertyValue
113 Nb4d6f50e1864466287f995875ba08c3b rdf:first N5ec39c14a4cb46239430bf3663a7efa4
114 rdf:rest N52f100547b1f459b88ae4caaa41c7986
115 Nd6299e29d6ea4c5a93ca6c42c8f81ad8 schema:affiliation https://www.grid.ac/institutes/grid.491814.1
116 schema:familyName Wingendorf
117 schema:givenName Insa
118 rdf:type schema:Person
119 Nda1f00e4c4154f0bbcbd82fd6da1a4c5 schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 Ne32d68b252784d3f9149fc4b5120f54f schema:name nlm_unique_id
122 schema:value 101263253
123 rdf:type schema:PropertyValue
124 Ne644debe1d4b4e748992ffa4e9856764 schema:affiliation https://www.grid.ac/institutes/grid.491814.1
125 schema:familyName Obermann
126 schema:givenName Mark
127 rdf:type schema:Person
128 Nf7f3242554e64c249e955c497b1f236f rdf:first Nd6299e29d6ea4c5a93ca6c42c8f81ad8
129 rdf:rest Nb4d6f50e1864466287f995875ba08c3b
130 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
131 schema:name Medical and Health Sciences
132 rdf:type schema:DefinedTerm
133 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
134 schema:name Clinical Sciences
135 rdf:type schema:DefinedTerm
136 sg:journal.1297400 schema:issn 1468-6708
137 1745-6215
138 schema:name Trials
139 rdf:type schema:Periodical
140 sg:pub.10.1186/1745-6215-15-322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044694346
141 https://doi.org/10.1186/1745-6215-15-322
142 rdf:type schema:CreativeWork
143 sg:pub.10.1186/s12883-015-0292-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013456667
144 https://doi.org/10.1186/s12883-015-0292-6
145 rdf:type schema:CreativeWork
146 https://app.dimensions.ai/details/publication/pub.1077619384 schema:CreativeWork
147 https://app.dimensions.ai/details/publication/pub.1078802651 schema:CreativeWork
148 https://app.dimensions.ai/details/publication/pub.1080703684 schema:CreativeWork
149 https://doi.org/10.1002/14651858.cd010820.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043896497
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1016/0003-9993(91)90010-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1054541205
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/0895-4356(88)90084-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042123582
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.apmr.2003.06.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005998799
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.apmr.2005.08.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043911380
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.apmr.2008.02.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001889946
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/s0140-6736(98)09477-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043776499
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1053/apmr.2002.35089 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042349130
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1053/apmr.2003.50110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025220434
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1080/09638280600919764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008083925
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1080/10749357.2016.1138672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048645127
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1080/17483107.2018.1449019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101499257
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1093/ptj/69.11.990 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079406171
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1097/00000421-198212000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045278392
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1097/00002060-200212000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043511311
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1097/01.phm.0000137313.14480.ce schema:sameAs https://app.dimensions.ai/details/publication/pub.1015535664
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1097/hjh.0b013e3281fc975a schema:sameAs https://app.dimensions.ai/details/publication/pub.1012616091
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1097/mrr.0b013e32832a62ad schema:sameAs https://app.dimensions.ai/details/publication/pub.1006087514
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1097/phm.0000000000000135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012505247
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1136/jnnp.48.1.7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043691363
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1136/jnnp.52.11.1267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048503202
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1136/jnnp.72.4.473 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029302734
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1155/2012/298375 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024002787
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1155/2016/9346374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047314887
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1161/01.str.0000143153.76460.7d schema:sameAs https://app.dimensions.ai/details/publication/pub.1044865502
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1161/01.str.32.6.1279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009854358
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1161/str.0000000000000024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021520827
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1177/0269215508101741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063798827
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1177/1545968308326635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064059125
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1177/1545968311433426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005365152
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1177/1545968314535985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032951333
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1191/0269215504cr843oa schema:sameAs https://app.dimensions.ai/details/publication/pub.1064150136
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1212/01.wnl.0000145605.20476.07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064346564
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1371/journal.pone.0131048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030183678
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1519/jsc.0000000000001520 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006727002
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1519/jsc.0b013e3181d32e29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044565021
220 rdf:type schema:CreativeWork
221 https://doi.org/10.2340/16501977-2183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070754163
222 rdf:type schema:CreativeWork
223 https://doi.org/10.2522/ptj.20080285 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025336179
224 rdf:type schema:CreativeWork
225 https://doi.org/10.7326/0003-4819-158-3-201302050-00583 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073713447
226 rdf:type schema:CreativeWork
227 https://www.grid.ac/institutes/grid.4488.0 schema:alternateName TU Dresden
228 schema:name Department of Public Health, Dresden Medical School, Technical University Dresden, Dresden, Germany
229 rdf:type schema:Organization
230 https://www.grid.ac/institutes/grid.491814.1 schema:alternateName Asklepios Kliniken Schildautal
231 schema:name Asklepios Kliniken Schildautal, Klinik für Neurologische Rehabilitation und Klinik für Neurologische Frührehabilitation, Physiotherapie, Seesen, Germany
232 Asklepios Kliniken Schildautal, Klinik für Neurologische Rehabilitation, Seesen, Germany
233 Asklepios Kliniken Schildautal, Physiotherapie, Seesen, Germany
234 Asklepios Kliniken Schildautal, Zentrum für Neurologie, Seesen, Germany
235 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...