Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Alba Sánchez, Christine Thomas, Friederike Deeken, Sören Wagner, Stefan Klöppel, Felix Kentischer, Christine A. F. von Arnim, Michael Denkinger, Lars O. Conzelmann, Janine Biermann-Stallwitz, Stefanie Joos, Heidrun Sturm, Brigitte Metz, Ramona Auer, Yoanna Skrobik, Gerhard W. Eschweiler, Michael A. Rapp, PAWEL Study group

ABSTRACT

BACKGROUND: Postoperative delirium is a common disorder in older adults that is associated with higher morbidity and mortality, prolonged cognitive impairment, development of dementia, higher institutionalization rates, and rising healthcare costs. The probability of delirium after surgery increases with patients' age, with pre-existing cognitive impairment, and with comorbidities, and its diagnosis and treatment is dependent on the knowledge of diagnostic criteria, risk factors, and treatment options of the medical staff. In this study, we will investigate whether a cross-sectoral and multimodal intervention for preventing delirium can reduce the prevalence of delirium and postoperative cognitive decline (POCD) in patients older than 70 years undergoing elective surgery. Additionally, we will analyze whether the intervention is cost-effective. METHODS: The study will be conducted at five medical centers (with two or three surgical departments each) in the southwest of Germany. The study employs a stepped-wedge design with cluster randomization of the medical centers. Measurements are performed at six consecutive points: preadmission, preoperative, and postoperative with daily delirium screening up to day 7 and POCD evaluations at 2, 6, and 12 months after surgery. Recruitment goals are to enroll 1500 patients older than 70 years undergoing elective operative procedures (cardiac, thoracic, vascular, proximal big joints and spine, genitourinary, gastrointestinal, and general elective surgery procedures). DISCUSSION: Results of the trial should form the basis of future standards for preventing delirium and POCD in surgical wards. Key aims are the improvement of patient safety and quality of life, as well as the reduction of the long-term risk of conversion to dementia. Furthermore, from an economic perspective, we expect benefits and decreased costs for hospitals, patients, and healthcare insurances. TRIAL REGISTRATION: German Clinical Trials Register, DRKS00013311 . Registered on 10 November 2017. More... »

PAGES

71

References to SciGraph publications

  • 2013-04. Strategies for prevention of postoperative delirium: a systematic review and meta-analysis of randomized trials in CRITICAL CARE
  • 2018-07. Demenzsensible Versorgungsangebote im Allgemeinkrankenhaus in ZEITSCHRIFT FÜR GERONTOLOGIE UND GERIATRIE
  • 2017-02. Statistical Approaches to Longitudinal Data Analysis in Neurodegenerative Diseases: Huntington’s Disease as a Model in CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
  • 2017-12. Stepped wedge cluster randomized controlled trial designs: a review of reporting quality and design features in TRIALS
  • 2008-12. How to prevent perioperative delirium in the elderly? in ZEITSCHRIFT FÜR GERONTOLOGIE UND GERIATRIE
  • 2015-12. Five questions to consider before conducting a stepped wedge trial in TRIALS
  • 2004-08. Der Barthel–Index in der Geriatrie. Eine Kontextanalyse zum Hamburger Einstufungsmanual in ZEITSCHRIFT FÜR GERONTOLOGIE UND GERIATRIE
  • 2009-11. Validation of the Mini Nutritional Assessment short-form (MNA®-SF): A practical tool for identification of nutritional status in THE JOURNAL OF NUTRITION, HEALTH & AGING
  • 2015-08. The relation of SMI and the VSEP in a risk sample for neurodegenerative disorders in JOURNAL OF NEURAL TRANSMISSION
  • 2003-11. The reliability and stability of verbal working memory measures in BEHAVIOR RESEARCH METHODS
  • 2011-12. Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L) in QUALITY OF LIFE RESEARCH
  • 2014-03. The quality of life questionnaire EQ-5D-5L: psychometric properties and normative values for the general German population in QUALITY OF LIFE RESEARCH
  • 2009-06. How to Deal with Cost Differences at Baseline in PHARMACOECONOMICS
  • 2010-03. A Comparison of Three Scores to Screen for Delirium on the Surgical Ward in WORLD JOURNAL OF SURGERY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13063-018-3148-8

    DOI

    http://dx.doi.org/10.1186/s13063-018-3148-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1111576859

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30665435


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