Ontology type: schema:ScholarlyArticle Open Access: True
2018-12
AUTHORSAviv Ladanie, Benjamin Speich, Florian Naudet, Arnav Agarwal, Tiago V. Pereira, Francesco Sclafani, Juan Martin-Liberal, Thomas Schmid, Hannah Ewald, John P. A. Ioannidis, Heiner C. Bucher, Benjamin Kasenda, Lars G. Hemkens
ABSTRACTBACKGROUND: The available evidence on the benefits and harms of novel drugs and therapeutic biologics at the time of approval is reported in publicly available documents provided by the US Food and Drug Administration (FDA). We aimed to create a comprehensive database providing the relevant information required to systematically analyze and assess this early evidence in meta-epidemiological research. METHODS: We designed a modular and flexible database of systematically collected data. We identified all novel cancer drugs and therapeutic biologics approved by the FDA between 2000 and 2016, recorded regulatory characteristics, acquired the corresponding FDA approval documents, identified all clinical trials reported therein, and extracted trial design characteristics and treatment effects. Herein, we describe the rationale and design of the data collection process, particularly the organization of the data capture, the identification and eligibility assessment of clinical trials, and the data extraction activities. DISCUSSION: We established a comprehensive database on the comparative effects of drugs and therapeutic biologics approved by the FDA over a time period of 17 years for the treatment of cancer (solid tumors and hematological malignancies). The database provides information on the clinical trial evidence available at the time of approval of novel cancer treatments. The modular nature and structure of the database and the data collection processes allow updates, expansions, and adaption for a continuous meta-epidemiological analysis of novel drugs. The database allows us to systematically evaluate benefits and harms of novel drugs and therapeutic biologics. It provides a useful basis for meta-epidemiological research on the comparative effects of innovative cancer treatments and continuous evaluations of regulatory developments. More... »
PAGES505
http://scigraph.springernature.com/pub.10.1186/s13063-018-2877-z
DOIhttp://dx.doi.org/10.1186/s13063-018-2877-z
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1107112006
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30231912
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Public Health and Health Services",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Swiss Tropical and Public Health Institute",
"id": "https://www.grid.ac/institutes/grid.416786.a",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland",
"Swiss Tropical and Public Health Institute (Swiss TPH), Socinstrasse 57, 4002, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Ladanie",
"givenName": "Aviv",
"id": "sg:person.014206054063.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014206054063.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University Hospital of Basel",
"id": "https://www.grid.ac/institutes/grid.410567.1",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Speich",
"givenName": "Benjamin",
"id": "sg:person.01277203701.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277203701.36"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Univ Rennes, CHU Rennes, Inserm, CIC 1414 [(Centre d\u2019Investigation Clinique de Rennes)], 22 rue Henri Le Guilloux, 35000, Rennes, France"
],
"type": "Organization"
},
"familyName": "Naudet",
"givenName": "Florian",
"id": "sg:person.01027433464.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027433464.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "McMaster University",
"id": "https://www.grid.ac/institutes/grid.25073.33",
"name": [
"Department of Medicine, University of Toronto, 1 King\u2019s College Circle, M5S 1A8, Toronto, ON, Canada",
"Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, L8S 4K1, Hamilton, ON, Canada"
],
"type": "Organization"
},
"familyName": "Agarwal",
"givenName": "Arnav",
"id": "sg:person.0641121115.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641121115.01"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Health Technology Assessment Unit, Institute of Education and Health Sciences, Oswaldo Cruz German Hospital, Rua Jo\u00e3o Juli\u00e3o, 245 1\u00ba andar, Bloco D, 01323-040, S\u00e3o Paulo, Brazil"
],
"type": "Organization"
},
"familyName": "Pereira",
"givenName": "Tiago V.",
"id": "sg:person.01306312510.44",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306312510.44"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Royal Marsden NHS Foundation Trust",
"id": "https://www.grid.ac/institutes/grid.5072.0",
"name": [
"Department of Medicine, The Royal Marsden NHS Foundation Trust, Downs Road, SM2 5PT, Sutton, Surrey, UK"
],
"type": "Organization"
},
"familyName": "Sclafani",
"givenName": "Francesco",
"id": "sg:person.0653217174.51",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653217174.51"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitari Vall d'Hebron",
"id": "https://www.grid.ac/institutes/grid.411083.f",
"name": [
"Catalan Institute of Oncology (ICO) Hospitalet, Melanoma, Sarcoma and GU Tumors Unit, Av Gran Via de L\u2019Hospitalet 199-203, 08908, Barcelona, Spain",
"Vall d\u2019Hebron Institute of Oncology (VHIO), Early Drug Development Unit (UITM), Pg Vall d\u2019Hebron, 119-129, 08035, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Martin-Liberal",
"givenName": "Juan",
"id": "sg:person.01165767756.07",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165767756.07"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"St. Clara Hospital, Kleinriehenstrasse 30, 4058, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Schmid",
"givenName": "Thomas",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Basel",
"id": "https://www.grid.ac/institutes/grid.6612.3",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland",
"Swiss Tropical and Public Health Institute (Swiss TPH), Socinstrasse 57, 4002, Basel, Switzerland",
"University Medical Library, University of Basel, Sch\u00f6nbeinstrasse 18-20, 4056, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Ewald",
"givenName": "Hannah",
"id": "sg:person.01120207621.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120207621.57"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Stanford University",
"id": "https://www.grid.ac/institutes/grid.168010.e",
"name": [
"Meta-Research Innovation Center at Stanford (METRICS), Stanford University, 1265 Welch Road, 94305, Stanford, CA, USA",
"Department of Medicine, Stanford University School of Medicine, 1265 Welch Road, 94305, Stanford, CA, USA",
"Department of Health Research and Policy, Stanford University School of Medicine, 1265 Welch Road, 94305, Stanford, CA, USA",
"Department of Biomedical Data Science, Stanford University School of Medicine, 1265 Welch Road, 94305, Stanford, CA, USA",
"Department of Statistics, Stanford University School of Humanities and Sciences, 1265 Welch Road, 94305, Stanford, CA, USA"
],
"type": "Organization"
},
"familyName": "Ioannidis",
"givenName": "John P. A.",
"id": "sg:person.015607417277.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015607417277.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University Hospital of Basel",
"id": "https://www.grid.ac/institutes/grid.410567.1",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Bucher",
"givenName": "Heiner C.",
"id": "sg:person.010423442262.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010423442262.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University Hospital of Basel",
"id": "https://www.grid.ac/institutes/grid.410567.1",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland",
"Medical Oncology, University Hospital and University of Basel, Petersgraben 4, 4031, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Kasenda",
"givenName": "Benjamin",
"id": "sg:person.01074024017.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074024017.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University Hospital of Basel",
"id": "https://www.grid.ac/institutes/grid.410567.1",
"name": [
"Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital and University of Basel, Spitalstrasse 12, 4031, Basel, Switzerland"
],
"type": "Organization"
},
"familyName": "Hemkens",
"givenName": "Lars G.",
"id": "sg:person.0653435747.12",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653435747.12"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1634/theoncologist.2012-0235",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009320091"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cpt.174",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018969295"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jnci/djr062",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020994293"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jnci/djq463",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022269923"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pmed.0020422",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022611067"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pmed.0020422",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022611067"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1377/hlthaff.2012.0541",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023052632"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023335611"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jamaoncol.2016.4166",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025581524"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.h4679",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029445366"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmp1402114",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032518706"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jamaoto.2014.1570",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034108946"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2009.23.6018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035632304"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.f5992",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036154858"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13023-015-0349-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038382727",
"https://doi.org/10.1186/s13023-015-0349-z"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.mayocp.2016.02.012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038485309"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jnci/djp515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040137647"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jnci/djp515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040137647"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2011.539",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040449757"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2013.282034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041720852"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.critrevonc.2013.01.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046266475"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jamainternmed.2015.5868",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049232834"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2011.769",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050783821"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1745-6215-8-16",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052599734",
"https://doi.org/10.1186/1745-6215-8-16"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.11613/bm.2012.031",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063347969"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2146/ajhp120515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069100229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2146/ajhp120515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069100229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2146/ajhp120515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069100229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2146/ajhp120515",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069100229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/esmoopen-2016-000125",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083507875"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/esmoopen-2016-000125",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083507875"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrclinonc.2017.18",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083850261",
"https://doi.org/10.1038/nrclinonc.2017.18"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cncr.30622",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083853683"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ctrv.2017.03.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084739916"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.j1680",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085320390"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.j1680",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085320390"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/1468-0009.12261",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085908186"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ejca.2017.05.029",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1086256594"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2017.9415",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091209156"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.31061",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091865421"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.j4530",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092090892"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.j4530",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092090892"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jnci/djx232",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092154092"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.7573/dic.212507",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092684144"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jclinepi.2018.01.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1100941306"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.k2815",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105467742"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.k2815",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105467742"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.k2815",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105467742"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-12",
"datePublishedReg": "2018-12-01",
"description": "BACKGROUND: The available evidence on the benefits and harms of novel drugs and therapeutic biologics at the time of approval is reported in publicly available documents provided by the US Food and Drug Administration (FDA). We aimed to create a comprehensive database providing the relevant information required to systematically analyze and assess this early evidence in meta-epidemiological research.\nMETHODS: We designed a modular and flexible database of systematically collected data. We identified all novel cancer drugs and therapeutic biologics approved by the FDA between 2000 and 2016, recorded regulatory characteristics, acquired the corresponding FDA approval documents, identified all clinical trials reported therein, and extracted trial design characteristics and treatment effects. Herein, we describe the rationale and design of the data collection process, particularly the organization of the data capture, the identification and eligibility assessment of clinical trials, and the data extraction activities.\nDISCUSSION: We established a comprehensive database on the comparative effects of drugs and therapeutic biologics approved by the FDA over a time period of 17\u00a0years for the treatment of cancer (solid tumors and hematological malignancies). The database provides information on the clinical trial evidence available at the time of approval of novel cancer treatments. The modular nature and structure of the database and the data collection processes allow updates, expansions, and adaption for a continuous meta-epidemiological analysis of novel drugs. The database allows us to systematically evaluate benefits and harms of novel drugs and therapeutic biologics. It provides a useful basis for meta-epidemiological research on the comparative effects of innovative cancer treatments and continuous evaluations of regulatory developments.",
"genre": "research_article",
"id": "sg:pub.10.1186/s13063-018-2877-z",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1297400",
"issn": [
"1468-6708",
"1745-6215"
],
"name": "Trials",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "19"
}
],
"name": "The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs",
"pagination": "505",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"3431499b642e1dfe48a3228835213d6e580b9aa924f5292c00d023e9fe8cf11f"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30231912"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101263253"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13063-018-2877-z"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1107112006"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13063-018-2877-z",
"https://app.dimensions.ai/details/publication/pub.1107112006"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T18:25",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000540.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1186%2Fs13063-018-2877-z"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13063-018-2877-z'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13063-018-2877-z'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13063-018-2877-z'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13063-018-2877-z'
This table displays all metadata directly associated to this object as RDF triples.
303 TRIPLES
21 PREDICATES
67 URIs
21 LITERALS
9 BLANK NODES