Projection of participant recruitment to primary care research: a qualitative study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

David White, Daniel Hind

ABSTRACT

BACKGROUND: Recruitment to clinical trials remains a challenge, particularly in primary care settings. Initial projections of participant recruitment need to be as accurate as possible in order to avoid the financial, clinical and ethical costs of trial extensions or failures. However, estimation of recruitment rates is challenging and often poorly executed, if attempted at all. We used qualitative methods to explore the experiences and views of researchers on the planning of recruitment in this setting. METHODS: Participants had registered accrual to a UK-based primary care research study between April 2009 and March 2012. We conducted nine interviews with chief investigators or study managers, using a semi-structured topic guide. Analysis was conducted using the framework approach. RESULTS: Three themes are presented: 1) the factors affecting recruitment rates, 2) the use of planning techniques, and 3) influences on poor estimation. 1) A large number of factors affecting recruitment rates were discussed, including those relating to the study protocol, the clinical setting and the research setting. Use of targeted mail-outs to invite apparently eligible individuals to participate was preferred in order to eliminate some of the uncertainty in the recruitment rate associated with opportunistic clinician referrals. 2) The importance of pilot work was stressed. We identified significant uncertainty as to how best to schedule trial timelines to maximise efficiency. 3) Several potential sources of bias involved in the estimation of recruitment rates were explored and framed as technological, psychological or political factors. CONCLUSIONS: We found a large number of factors that interviewees felt impact recruitment rates to primary care research and highlighted the complexity of realistic estimation. Suitable early planning of the recruitment process is essential, and there may be potential to improve the projection of trial timelines by reducing biases involved in the process. Further research is needed to develop formal approaches that would be suitable for use in this setting. More... »

PAGES

473

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13063-015-1002-9

DOI

http://dx.doi.org/10.1186/s13063-015-1002-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007658620

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26482231


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Attitude of Health Personnel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Clinical Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interviews as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Patient Selection", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Primary Health Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Qualitative Research", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Referral and Consultation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Research Personnel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sample Size", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Selection Bias", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Sheffield", 
          "id": "https://www.grid.ac/institutes/grid.11835.3e", 
          "name": [
            "Clinical Trials Research Unit, University of Sheffield, Regent Court, 30 Regent Street, S1 4DA, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "David", 
        "id": "sg:person.01173646365.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173646365.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sheffield", 
          "id": "https://www.grid.ac/institutes/grid.11835.3e", 
          "name": [
            "Clinical Trials Research Unit, University of Sheffield, Regent Court, 30 Regent Street, S1 4DA, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hind", 
        "givenName": "Daniel", 
        "id": "sg:person.01235743421.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235743421.96"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90003-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001239473"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90003-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001239473"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(13)62297-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001270672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0044183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001285878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cpt1979255part2751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005765608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09654310701747936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005948383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmq108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005987389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/17.2.187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006080864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/08870440903194015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011421919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5172/conu.2009.34.1.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012964699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1745-6215-14-166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013596285", 
          "https://doi.org/10.1186/1745-6215-14-166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2010.156885", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015764420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2010.156885", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015764420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2288-7-42", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015873915", 
          "https://doi.org/10.1186/1471-2288-7-42"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)62351-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017346852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0197-2456(96)00236-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017770593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmg609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018630321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cct.2006.08.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018659929"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1467-789x.2009.00567.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019042965"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1467-789x.2009.00567.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019042965"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmm019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019483382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.schres.2010.04.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020778056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmn085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023098011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90004-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023959668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90004-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023959668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1525822x05279903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025610663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1525822x05279903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025610663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2006.11.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026281628"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.f3649", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028058301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1745-6215-7-34", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030978952", 
          "https://doi.org/10.1186/1745-6215-7-34"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1037/0022-3514.77.2.221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031592228"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.f5248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032697304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmp037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034621837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.f5776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036257511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3102/0013189x021006013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036577021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3102/0013189x021006013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036577021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0011000006287390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038358588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0011000006287390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038358588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2014.10.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039081646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gps.4034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040653819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(03)14576-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041592646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmjopen-2014-005874", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043630459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2288-10-63", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043640186", 
          "https://doi.org/10.1186/1471-2288-10-63"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/emj.20.4.359", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043843851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1108/03090590310468903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045014055"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90020-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045245005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(87)90020-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045245005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmm051", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046990141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.4780030425", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047918204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cct.2013.07.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048669119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2288-12-122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049572571", 
          "https://doi.org/10.1186/1471-2288-12-122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/20.1.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050948273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp12x654759", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050973118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.185.4157.1124", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062510354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1468794112446106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064023843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1468794112446106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064023843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/1914185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069641248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7748/nr.21.5.28.e1232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073924675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/135581969600100205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074346462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/135581969600100205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074346462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074668652", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aje.a112138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074697793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074783081", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5694/j.1326-5377.2001.tb143189.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074783081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074954736", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076608141", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078597945", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081938676", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082165293", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4324/9780203413081_chapter_9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1087792894"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-12", 
    "datePublishedReg": "2015-12-01", 
    "description": "BACKGROUND: Recruitment to clinical trials remains a challenge, particularly in primary care settings. Initial projections of participant recruitment need to be as accurate as possible in order to avoid the financial, clinical and ethical costs of trial extensions or failures. However, estimation of recruitment rates is challenging and often poorly executed, if attempted at all. We used qualitative methods to explore the experiences and views of researchers on the planning of recruitment in this setting.\nMETHODS: Participants had registered accrual to a UK-based primary care research study between April 2009 and March 2012. We conducted nine interviews with chief investigators or study managers, using a semi-structured topic guide. Analysis was conducted using the framework approach.\nRESULTS: Three themes are presented: 1) the factors affecting recruitment rates, 2) the use of planning techniques, and 3) influences on poor estimation. 1) A large number of factors affecting recruitment rates were discussed, including those relating to the study protocol, the clinical setting and the research setting. Use of targeted mail-outs to invite apparently eligible individuals to participate was preferred in order to eliminate some of the uncertainty in the recruitment rate associated with opportunistic clinician referrals. 2) The importance of pilot work was stressed. We identified significant uncertainty as to how best to schedule trial timelines to maximise efficiency. 3) Several potential sources of bias involved in the estimation of recruitment rates were explored and framed as technological, psychological or political factors.\nCONCLUSIONS: We found a large number of factors that interviewees felt impact recruitment rates to primary care research and highlighted the complexity of realistic estimation. Suitable early planning of the recruitment process is essential, and there may be potential to improve the projection of trial timelines by reducing biases involved in the process. Further research is needed to develop formal approaches that would be suitable for use in this setting.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s13063-015-1002-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1297400", 
        "issn": [
          "1468-6708", 
          "1745-6215"
        ], 
        "name": "Trials", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "Projection of participant recruitment to primary care research: a qualitative study", 
    "pagination": "473", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "247af691d757679efa2a13f8ed5df2c85edce11aa7887f28cdc2357b458b52d2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26482231"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101263253"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13063-015-1002-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1007658620"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13063-015-1002-9", 
      "https://app.dimensions.ai/details/publication/pub.1007658620"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000510.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2Fs13063-015-1002-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13063-015-1002-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13063-015-1002-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13063-015-1002-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13063-015-1002-9'


 

This table displays all metadata directly associated to this object as RDF triples.

310 TRIPLES      21 PREDICATES      103 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13063-015-1002-9 schema:about N15876b08bcb84595801f9ed36775da00
2 N22a55ab1b38b481394587edb8eb8515d
3 N2533f490166b420fb1ca207f6ebbf8e0
4 N2d61b97602094a6387818fb7a4d0a025
5 N58a140ad228741519898fbadbbc7aa93
6 N6945486d683d4c8e855d6b3d7480b794
7 N8448064252f94051b4e90cfb7468d442
8 N886598f4dd1e40cfa4fed2a5d2923a6b
9 N93bdaaeb10bc40a9b9d9fe4ef77cc841
10 N994edda638914a9fbc485180d9fa6eea
11 N99f9df877f0b49759635e89dea3c115d
12 Na274ea97481b462c8562048ec1bac835
13 Nc09992efef034d189eee283a9a065083
14 Ne5e64b64a7d149edb95832f99f7112d9
15 anzsrc-for:11
16 anzsrc-for:1117
17 schema:author Na5b36219cfa348b789695f51fb2b4e23
18 schema:citation sg:pub.10.1186/1471-2288-10-63
19 sg:pub.10.1186/1471-2288-12-122
20 sg:pub.10.1186/1471-2288-7-42
21 sg:pub.10.1186/1745-6215-14-166
22 sg:pub.10.1186/1745-6215-7-34
23 https://app.dimensions.ai/details/publication/pub.1074668652
24 https://app.dimensions.ai/details/publication/pub.1074783081
25 https://app.dimensions.ai/details/publication/pub.1074954736
26 https://app.dimensions.ai/details/publication/pub.1076608141
27 https://app.dimensions.ai/details/publication/pub.1078597945
28 https://app.dimensions.ai/details/publication/pub.1081938676
29 https://app.dimensions.ai/details/publication/pub.1082165293
30 https://doi.org/10.1002/cpt1979255part2751
31 https://doi.org/10.1002/gps.4034
32 https://doi.org/10.1002/sim.4780030425
33 https://doi.org/10.1016/0197-2456(87)90003-1
34 https://doi.org/10.1016/0197-2456(87)90004-3
35 https://doi.org/10.1016/0197-2456(87)90020-1
36 https://doi.org/10.1016/j.cct.2006.08.004
37 https://doi.org/10.1016/j.cct.2013.07.009
38 https://doi.org/10.1016/j.jclinepi.2006.11.010
39 https://doi.org/10.1016/j.jclinepi.2014.10.007
40 https://doi.org/10.1016/j.schres.2010.04.003
41 https://doi.org/10.1016/s0140-6736(03)14576-x
42 https://doi.org/10.1016/s0140-6736(10)62351-3
43 https://doi.org/10.1016/s0140-6736(13)62297-7
44 https://doi.org/10.1016/s0197-2456(96)00236-x
45 https://doi.org/10.1037/0022-3514.77.2.221
46 https://doi.org/10.1080/08870440903194015
47 https://doi.org/10.1080/09654310701747936
48 https://doi.org/10.1093/fampra/17.2.187
49 https://doi.org/10.1093/fampra/20.1.83
50 https://doi.org/10.1093/fampra/cmg609
51 https://doi.org/10.1093/fampra/cmm019
52 https://doi.org/10.1093/fampra/cmm051
53 https://doi.org/10.1093/fampra/cmn085
54 https://doi.org/10.1093/fampra/cmp037
55 https://doi.org/10.1093/fampra/cmq108
56 https://doi.org/10.1093/oxfordjournals.aje.a112138
57 https://doi.org/10.1108/03090590310468903
58 https://doi.org/10.1111/j.1467-789x.2009.00567.x
59 https://doi.org/10.1126/science.185.4157.1124
60 https://doi.org/10.1136/bmj.f3649
61 https://doi.org/10.1136/bmj.f5248
62 https://doi.org/10.1136/bmj.f5776
63 https://doi.org/10.1136/bmjopen-2014-005874
64 https://doi.org/10.1136/emj.20.4.359
65 https://doi.org/10.1136/thx.2010.156885
66 https://doi.org/10.1177/0011000006287390
67 https://doi.org/10.1177/135581969600100205
68 https://doi.org/10.1177/1468794112446106
69 https://doi.org/10.1177/1525822x05279903
70 https://doi.org/10.1371/journal.pone.0044183
71 https://doi.org/10.2307/1914185
72 https://doi.org/10.3102/0013189x021006013
73 https://doi.org/10.3399/bjgp12x654759
74 https://doi.org/10.4324/9780203413081_chapter_9
75 https://doi.org/10.5172/conu.2009.34.1.002
76 https://doi.org/10.5694/j.1326-5377.2001.tb143189.x
77 https://doi.org/10.7748/nr.21.5.28.e1232
78 schema:datePublished 2015-12
79 schema:datePublishedReg 2015-12-01
80 schema:description BACKGROUND: Recruitment to clinical trials remains a challenge, particularly in primary care settings. Initial projections of participant recruitment need to be as accurate as possible in order to avoid the financial, clinical and ethical costs of trial extensions or failures. However, estimation of recruitment rates is challenging and often poorly executed, if attempted at all. We used qualitative methods to explore the experiences and views of researchers on the planning of recruitment in this setting. METHODS: Participants had registered accrual to a UK-based primary care research study between April 2009 and March 2012. We conducted nine interviews with chief investigators or study managers, using a semi-structured topic guide. Analysis was conducted using the framework approach. RESULTS: Three themes are presented: 1) the factors affecting recruitment rates, 2) the use of planning techniques, and 3) influences on poor estimation. 1) A large number of factors affecting recruitment rates were discussed, including those relating to the study protocol, the clinical setting and the research setting. Use of targeted mail-outs to invite apparently eligible individuals to participate was preferred in order to eliminate some of the uncertainty in the recruitment rate associated with opportunistic clinician referrals. 2) The importance of pilot work was stressed. We identified significant uncertainty as to how best to schedule trial timelines to maximise efficiency. 3) Several potential sources of bias involved in the estimation of recruitment rates were explored and framed as technological, psychological or political factors. CONCLUSIONS: We found a large number of factors that interviewees felt impact recruitment rates to primary care research and highlighted the complexity of realistic estimation. Suitable early planning of the recruitment process is essential, and there may be potential to improve the projection of trial timelines by reducing biases involved in the process. Further research is needed to develop formal approaches that would be suitable for use in this setting.
81 schema:genre research_article
82 schema:inLanguage en
83 schema:isAccessibleForFree true
84 schema:isPartOf N003c0bf8f88d445285bb1ee5fcfae5ce
85 N03414625d8ab4ddaaf44b5155fdf19d6
86 sg:journal.1297400
87 schema:name Projection of participant recruitment to primary care research: a qualitative study
88 schema:pagination 473
89 schema:productId N56ebd7353a6d4828a2bbd339b1268993
90 N6b00958853d8466c80d3eb09568a7f8c
91 N76d4a5655fd243d1abed67fe61df93b1
92 N99ceadc0336a4a61978301f53861801c
93 Nfd114e015bde4fcfa089c79ca2786472
94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007658620
95 https://doi.org/10.1186/s13063-015-1002-9
96 schema:sdDatePublished 2019-04-10T22:31
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N0983653e913746709a639c50164aa415
99 schema:url http://link.springer.com/10.1186%2Fs13063-015-1002-9
100 sgo:license sg:explorer/license/
101 sgo:sdDataset articles
102 rdf:type schema:ScholarlyArticle
103 N003c0bf8f88d445285bb1ee5fcfae5ce schema:issueNumber 1
104 rdf:type schema:PublicationIssue
105 N03414625d8ab4ddaaf44b5155fdf19d6 schema:volumeNumber 16
106 rdf:type schema:PublicationVolume
107 N0983653e913746709a639c50164aa415 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N15876b08bcb84595801f9ed36775da00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Patient Selection
111 rdf:type schema:DefinedTerm
112 N22a55ab1b38b481394587edb8eb8515d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Clinical Trials as Topic
114 rdf:type schema:DefinedTerm
115 N2533f490166b420fb1ca207f6ebbf8e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Sample Size
117 rdf:type schema:DefinedTerm
118 N2d61b97602094a6387818fb7a4d0a025 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Female
120 rdf:type schema:DefinedTerm
121 N56ebd7353a6d4828a2bbd339b1268993 schema:name readcube_id
122 schema:value 247af691d757679efa2a13f8ed5df2c85edce11aa7887f28cdc2357b458b52d2
123 rdf:type schema:PropertyValue
124 N58a140ad228741519898fbadbbc7aa93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Humans
126 rdf:type schema:DefinedTerm
127 N6945486d683d4c8e855d6b3d7480b794 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Qualitative Research
129 rdf:type schema:DefinedTerm
130 N6b00958853d8466c80d3eb09568a7f8c schema:name nlm_unique_id
131 schema:value 101263253
132 rdf:type schema:PropertyValue
133 N76d4a5655fd243d1abed67fe61df93b1 schema:name doi
134 schema:value 10.1186/s13063-015-1002-9
135 rdf:type schema:PropertyValue
136 N8448064252f94051b4e90cfb7468d442 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Time Factors
138 rdf:type schema:DefinedTerm
139 N86127efa4dba4a48add6c0f3937f693f rdf:first sg:person.01235743421.96
140 rdf:rest rdf:nil
141 N886598f4dd1e40cfa4fed2a5d2923a6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Interviews as Topic
143 rdf:type schema:DefinedTerm
144 N93bdaaeb10bc40a9b9d9fe4ef77cc841 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Male
146 rdf:type schema:DefinedTerm
147 N994edda638914a9fbc485180d9fa6eea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Selection Bias
149 rdf:type schema:DefinedTerm
150 N99ceadc0336a4a61978301f53861801c schema:name pubmed_id
151 schema:value 26482231
152 rdf:type schema:PropertyValue
153 N99f9df877f0b49759635e89dea3c115d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Attitude of Health Personnel
155 rdf:type schema:DefinedTerm
156 Na274ea97481b462c8562048ec1bac835 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Primary Health Care
158 rdf:type schema:DefinedTerm
159 Na5b36219cfa348b789695f51fb2b4e23 rdf:first sg:person.01173646365.07
160 rdf:rest N86127efa4dba4a48add6c0f3937f693f
161 Nc09992efef034d189eee283a9a065083 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Research Personnel
163 rdf:type schema:DefinedTerm
164 Ne5e64b64a7d149edb95832f99f7112d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Referral and Consultation
166 rdf:type schema:DefinedTerm
167 Nfd114e015bde4fcfa089c79ca2786472 schema:name dimensions_id
168 schema:value pub.1007658620
169 rdf:type schema:PropertyValue
170 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
171 schema:name Medical and Health Sciences
172 rdf:type schema:DefinedTerm
173 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
174 schema:name Public Health and Health Services
175 rdf:type schema:DefinedTerm
176 sg:journal.1297400 schema:issn 1468-6708
177 1745-6215
178 schema:name Trials
179 rdf:type schema:Periodical
180 sg:person.01173646365.07 schema:affiliation https://www.grid.ac/institutes/grid.11835.3e
181 schema:familyName White
182 schema:givenName David
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173646365.07
184 rdf:type schema:Person
185 sg:person.01235743421.96 schema:affiliation https://www.grid.ac/institutes/grid.11835.3e
186 schema:familyName Hind
187 schema:givenName Daniel
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235743421.96
189 rdf:type schema:Person
190 sg:pub.10.1186/1471-2288-10-63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043640186
191 https://doi.org/10.1186/1471-2288-10-63
192 rdf:type schema:CreativeWork
193 sg:pub.10.1186/1471-2288-12-122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049572571
194 https://doi.org/10.1186/1471-2288-12-122
195 rdf:type schema:CreativeWork
196 sg:pub.10.1186/1471-2288-7-42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015873915
197 https://doi.org/10.1186/1471-2288-7-42
198 rdf:type schema:CreativeWork
199 sg:pub.10.1186/1745-6215-14-166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013596285
200 https://doi.org/10.1186/1745-6215-14-166
201 rdf:type schema:CreativeWork
202 sg:pub.10.1186/1745-6215-7-34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030978952
203 https://doi.org/10.1186/1745-6215-7-34
204 rdf:type schema:CreativeWork
205 https://app.dimensions.ai/details/publication/pub.1074668652 schema:CreativeWork
206 https://app.dimensions.ai/details/publication/pub.1074783081 schema:CreativeWork
207 https://app.dimensions.ai/details/publication/pub.1074954736 schema:CreativeWork
208 https://app.dimensions.ai/details/publication/pub.1076608141 schema:CreativeWork
209 https://app.dimensions.ai/details/publication/pub.1078597945 schema:CreativeWork
210 https://app.dimensions.ai/details/publication/pub.1081938676 schema:CreativeWork
211 https://app.dimensions.ai/details/publication/pub.1082165293 schema:CreativeWork
212 https://doi.org/10.1002/cpt1979255part2751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005765608
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1002/gps.4034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040653819
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1002/sim.4780030425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047918204
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/0197-2456(87)90003-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001239473
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/0197-2456(87)90004-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023959668
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/0197-2456(87)90020-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045245005
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/j.cct.2006.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018659929
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/j.cct.2013.07.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048669119
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/j.jclinepi.2006.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026281628
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/j.jclinepi.2014.10.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039081646
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1016/j.schres.2010.04.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020778056
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/s0140-6736(03)14576-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041592646
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/s0140-6736(10)62351-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017346852
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/s0140-6736(13)62297-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001270672
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/s0197-2456(96)00236-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017770593
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1037/0022-3514.77.2.221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031592228
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1080/08870440903194015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011421919
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1080/09654310701747936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005948383
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1093/fampra/17.2.187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006080864
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1093/fampra/20.1.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050948273
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1093/fampra/cmg609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018630321
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1093/fampra/cmm019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019483382
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1093/fampra/cmm051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046990141
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1093/fampra/cmn085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023098011
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1093/fampra/cmp037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034621837
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1093/fampra/cmq108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005987389
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1093/oxfordjournals.aje.a112138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074697793
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1108/03090590310468903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045014055
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1111/j.1467-789x.2009.00567.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019042965
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1126/science.185.4157.1124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062510354
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1136/bmj.f3649 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028058301
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1136/bmj.f5248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032697304
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1136/bmj.f5776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036257511
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1136/bmjopen-2014-005874 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043630459
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1136/emj.20.4.359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043843851
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1136/thx.2010.156885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015764420
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1177/0011000006287390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038358588
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1177/135581969600100205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074346462
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1177/1468794112446106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064023843
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1177/1525822x05279903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025610663
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1371/journal.pone.0044183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001285878
293 rdf:type schema:CreativeWork
294 https://doi.org/10.2307/1914185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069641248
295 rdf:type schema:CreativeWork
296 https://doi.org/10.3102/0013189x021006013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036577021
297 rdf:type schema:CreativeWork
298 https://doi.org/10.3399/bjgp12x654759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050973118
299 rdf:type schema:CreativeWork
300 https://doi.org/10.4324/9780203413081_chapter_9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1087792894
301 rdf:type schema:CreativeWork
302 https://doi.org/10.5172/conu.2009.34.1.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012964699
303 rdf:type schema:CreativeWork
304 https://doi.org/10.5694/j.1326-5377.2001.tb143189.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1074783081
305 rdf:type schema:CreativeWork
306 https://doi.org/10.7748/nr.21.5.28.e1232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073924675
307 rdf:type schema:CreativeWork
308 https://www.grid.ac/institutes/grid.11835.3e schema:alternateName University of Sheffield
309 schema:name Clinical Trials Research Unit, University of Sheffield, Regent Court, 30 Regent Street, S1 4DA, Sheffield, UK
310 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...