Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-04-16

AUTHORS

Binsheng Gong, Dan Li, Rebecca Kusko, Natalia Novoradovskaya, Yifan Zhang, Shangzi Wang, Carlos Pabón-Peña, Zhihong Zhang, Kevin Lai, Wanshi Cai, Jennifer S LoCoco, Eric Lader, Todd A Richmond, Vinay K Mittal, Liang-Chun Liu, Donald J Johann, James C Willey, Pierre R Bushel, Ying Yu, Chang Xu, Guangchun Chen, Daniel Burgess, Simon Cawley, Kristina Giorda, Nathan Haseley, Fujun Qiu, Katherine Wilkins, Hanane Arib, Claire Attwooll, Kevin Babson, Longlong Bao, Wenjun Bao, Anne Bergstrom Lucas, Hunter Best, Ambica Bhandari, Halil Bisgin, James Blackburn, Thomas M Blomquist, Lisa Boardman, Blake Burgher, Daniel J Butler, Chia-Jung Chang, Alka Chaubey, Tao Chen, Marco Chierici, Christopher R Chin, Devin Close, Jeffrey Conroy, Jessica Cooley Coleman, Daniel J Craig, Erin Crawford, Angela Del Pozo, Ira W Deveson, Daniel Duncan, Agda Karina Eterovic, Xiaohui Fan, Jonathan Foox, Cesare Furlanello, Abhisek Ghosal, Sean Glenn, Meijian Guan, Christine Haag, Xinyi Hang, Scott Happe, Brittany Hennigan, Jennifer Hipp, Huixiao Hong, Kyle Horvath, Jianhong Hu, Li-Yuan Hung, Mirna Jarosz, Jennifer Kerkhof, Benjamin Kipp, David Philip Kreil, Paweł Łabaj, Pablo Lapunzina, Peng Li, Quan-Zhen Li, Weihua Li, Zhiguang Li, Yu Liang, Shaoqing Liu, Zhichao Liu, Charles Ma, Narasimha Marella, Rubén Martín-Arenas, Dalila B Megherbi, Qingchang Meng, Piotr A Mieczkowski, Tom Morrison, Donna Muzny, Baitang Ning, Barbara L Parsons, Cloud P Paweletz, Mehdi Pirooznia, Wubin Qu, Amelia Raymond, Paul Rindler, Rebecca Ringler, Bekim Sadikovic, Andreas Scherer, Egbert Schulze, Robert Sebra, Rita Shaknovich, Qiang Shi, Tieliu Shi, Juan Carlos Silla-Castro, Melissa Smith, Mario Solís López, Ping Song, Daniel Stetson, Maya Strahl, Alan Stuart, Julianna Supplee, Philippe Szankasi, Haowen Tan, Lin-Ya Tang, Yonghui Tao, Shraddha Thakkar, Danielle Thierry-Mieg, Jean Thierry-Mieg, Venkat J Thodima, David Thomas, Boris Tichý, Nikola Tom, Elena Vallespin Garcia, Suman Verma, Kimbley Walker, Charles Wang, Junwen Wang, Yexun Wang, Zhining Wen, Valtteri Wirta, Leihong Wu, Chunlin Xiao, Wenzhong Xiao, Shibei Xu, Mary Yang, Jianming Ying, Shun H Yip, Guangliang Zhang, Sa Zhang, Meiru Zhao, Yuanting Zheng, Xiaoyan Zhou, Christopher E Mason, Timothy Mercer, Weida Tong, Leming Shi, Wendell Jones, Joshua Xu

ABSTRACT

BACKGROUND: Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-led SEquence Quality Control project phase2 (SEQC2) effort, we perform a cross-platform multi-lab evaluation of eight Pan-Cancer panels to assess best practices for oncopanel sequencing. RESULTS: All panels demonstrate high sensitivity across targeted high-confidence coding regions and variant types for the variants previously verified to have variant allele frequency (VAF) in the 5-20% range. Sensitivity is reduced by utilizing VAF thresholds due to inherent variability in VAF measurements. Enforcing a VAF threshold for reporting has a positive impact on reducing false positive calls. Importantly, the false positive rate is found to be significantly higher outside the high-confidence coding regions, resulting in lower reproducibility. Thus, region restriction and VAF thresholds lead to low relative technical variability in estimating promising biomarkers and tumor mutational burden. CONCLUSION: This comprehensive study provides actionable guidelines for oncopanel sequencing and clear evidence that supports a simplified approach to assess the analytical performance of oncopanels. It will facilitate the rapid implementation, validation, and quality control of oncopanels in clinical use. More... »

PAGES

109

References to SciGraph publications

  • 2018-01-08. Genomic medicine for kidney disease in NATURE REVIEWS NEPHROLOGY
  • 2018-03-29. The emerging clinical relevance of genomics in cancer medicine in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2015-07-29. Next-generation sequencing to guide cancer therapy in GENOME MEDICINE
  • 2019-01-14. Tumor mutational load predicts survival after immunotherapy across multiple cancer types in NATURE GENETICS
  • 2014-08-24. A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control consortium in NATURE BIOTECHNOLOGY
  • 2004-03-09. Universal Reference RNA as a standard for microarray experiments in BMC GENOMICS
  • 2014-01-17. Sequencing depth and coverage: key considerations in genomic analyses in NATURE REVIEWS GENETICS
  • 2010-07-30. The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models in NATURE BIOTECHNOLOGY
  • 2017-04-19. Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden in GENOME MEDICINE
  • 2006-09-01. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements in NATURE BIOTECHNOLOGY
  • 2020-02-05. Pan-cancer analysis of whole genomes in NATURE
  • 2014-09-11. A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2021-04-16. A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency in GENOME BIOLOGY
  • 2016-07-26. The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine in GENOME MEDICINE
  • 2016-02-18. Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients in BRITISH JOURNAL OF CANCER
  • Journal

    TITLE

    Genome Biology

    ISSUE

    1

    VOLUME

    22

    Author Affiliations

  • Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Immuneering Corporation, One Broadway, 14th Floor, Cambridge, MA, 02142, USA.
  • Agilent Technologies, 11011 N Torrey Pines Rd, La Jolla, CA, 92037, USA.
  • Department of Information Science, University of Arkansas at Little Rock, 2801 S. Univ. Ave, Little Rock, AR, 72204, USA.
  • State Key Laboratory of Genetic Engineering, School of Life Sciences and Shanghai Cancer Hospital/Cancer Institute, Fudan University, Shanghai, 200438, China.
  • Agilent Technologies, 5301 Stevens Creek Blvd, Santa Clara, CA, 95051, USA.
  • Research and Development, Burning Rock Biotech, Shanghai, 201114, China.
  • Bioinformatics, Integrated DNA Technologies, Inc., 1710 Commercial Park, Coralville, IA, 52241, USA.
  • iGeneTech, 8 Shengmingyuan Rd., Zhongguancun Life Science Park, Changping District, Beijing, 100080, China.
  • Illumina Inc., 5200 Illumina Way, San Diego, CA, 92122, USA.
  • Research and Development, QIAGEN Sciences Inc., Frederick, MD, 21703, USA.
  • Market & Application Development Bioinformatics, Roche Sequencing Solutions Inc., 4300 Hacienda Dr, Pleasanton, CA, 94588, USA.
  • Thermo Fisher Scientific, 110 Miller Ave, Ann Arbor, MI, 48104, USA.
  • Clinical Diagnostic Division, Thermo Fisher Scientific, 46500 Kato Rd, Fremont, CA, 94538, USA.
  • Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA.
  • Departments of Medicine, Pathology, and Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Sciences Campus, 3000 Arlington Ave, Toledo, OH, 43614, USA.
  • National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.
  • Department of Immunology, Genomics and Microarray Core Facility, University of Texas Southwestern Medical Center, 5323 Harry Hine Blvd, Dallas, TX, 75390, USA.
  • Research and Development, Roche Sequencing Solutions Inc., 500 South Rosa Rd, Madison, WI, 53719, USA.
  • Clinical Sequencing Division, Thermo Fisher Scientific, 180 Oyster Point Blvd, South San Francisco, CA, 94080, USA.
  • Marketing, Integrated DNA Technologies, Inc., 1710 Commercial Park, Coralville, IA, 52241, USA.
  • Icahn Institute and Dept. of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.
  • Greenwood Genetic Center, 106 Gregor Mendel Circle, Greenwood, SC, 29646, USA.
  • Institute of Pathology, Fudan University, Shanghai, 200032, China.
  • JMP Life Sciences, SAS Institute Inc., Cary, NC, 27519, USA.
  • R&D Genomics MPS, Institute for Clinical and Experimental Pathology ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT, 84108, USA.
  • ResearchDx, Inc., 5 Mason, Irvine, CA, 92618, USA.
  • Department of Computer Science, Engineering and Physics, University of Michigan-Flint, Flint, MI, 48502, USA.
  • St Vincent's Clinical School, University of New South Wales, Sydney, NSW, 2010, Australia.
  • Lucas County Coroner's Office, 2595 Arlington Ave., Toledo, OH, 43614, USA.
  • Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 55905, USA.
  • OmniSeq, Inc. 700 Ellicott St, Buffalo, NY, 14203, USA.
  • Department of Physiology and Biophysics, Weill Cornell Medicine, Cornell University, New York, NY, 10065, USA.
  • Stanford Genome Technology Center, Stanford University, Palo Alto, CA, 94304, USA.
  • Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Fondazione Bruno Kessler, 38123, Trento, Italy.
  • Department of Medicine, College of Medicine and Life Sciences, The University of Toledo, Toledo, OH, 43614, USA.
  • EATRIS ERIC- European Infrastructure for Translational Medicine, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.
  • St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Cancer Genetics Inc, 201 Route 17 N, Meadows Office Building, Rutherford, NJ, 07070, USA.
  • Institute for Personalized Cancer Therapy, MD Anderson Cancer Center, 6565 MD Anderson Blvd, Houston, TX, 77030, USA.
  • Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
  • HK3 Lab, Milan, Italy.
  • Molecular Laboratory, Prof. F. Raue, Im Weiher 12, Heidelberg, Germany.
  • Agilent Technologies, 1834 State Hwy 71 West, Cedar Creek, TX, 78612, USA.
  • Department of Pathology, Strata Oncology, Inc., Ann Arbor, MI, 48103, USA.
  • Human Genome Sequencing Center, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA.
  • Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
  • NGS Products and Services, Integrated DNA Technologies, Inc., 1710 Commercial Park, Coralville, IA, 52241, USA.
  • Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, 800 Commissioners Rd E, London, Ontario, N6A5W9, Canada.
  • Division of Anatomic Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
  • Bioinformatics Research, Institute of Molecular Biotechnology, Boku University Vienna, Vienna, Austria.
  • Department of Biotechnology, Boku University, Vienna, Austria.
  • ITHACA, European Reference Network on Rare Congenital Malformations and Rare Intellectual Disability, European Commission, Lille, France.
  • Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences, No.17, Panjiayuan Nanli, Chaoyang District, Beijing, 100021, China.
  • Center of Genome and Personalized Medicine, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, 116044, Liaoning, China.
  • Geneis, 5 Guangshun North St., Chaoyang District, Beijing, 100102, China.
  • GeneSmile Ltd Co., Jiangsu Cancer Hospital, 42 Baiziting St., Xuanwu District, Nanjing, 210009, Jiangsu, China.
  • Genycell Biotech España, Calle Garrido Atienza, 18320 Santa Fe, Granada, Spain.
  • CMINDS Research Center, Department of Electrical and Computer Engineering, College of Engineering, University of Massachusetts Lowell, Lowell, MA, 01854, USA.
  • Department of Genetics, University of North Carolina, 250 Bell Tower Drive, Chapel Hill, NC, 27599, USA.
  • Accugenomics, Inc., 1410 Commonwealth Drive, Suite 105, Wilmington, NC, 20403, USA.
  • Translational Research Laboratory, Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, 360 Longwood Ave, Boston, MA, 02215, USA.
  • Bioinformatics and Computational Biology Laboratory, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Astrazeneca Pharmaceuticals, 35 Gatehouse Dr, Waltham, MA, 02451, USA.
  • Department of Pathology and Laboratory Medicine, Western University, London, Ontario, N6A3K7, Canada.
  • Institute for Molecular Medicine Finland (FIMM), Nordic EMBL Partnership for Molecular Medicine, HiLIFE Unit, Biomedicum Helsinki 2U (D302b), P.O. Box 20, (Tukholmankatu 8), FI-00014 University of Helsinki, Helsinki, Finland.
  • Laboratory for Molecular Genetics, Endocrine Practice, Im Weiher 12, 69121, Heidelberg, Germany.
  • Division of Systems Biology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Center for Bioinformatics and Computational Biology, and the Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Rd, Shanghai, 200241, China.
  • National Centre for Cardiovascular Research (CNIC), Madrid, Spain.
  • Primbio Genes Biotechnology, Building C6-501, Biolake, No.666 Gaoxin Ave., East Lake High-tech Development Zone, Wuhan, 430074, Hubei, China.
  • National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD, 20894, USA.
  • Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia.
  • Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
  • Division of Microbiology & Molecular Genetics, Department of Basic Sciences, School of Medicine, Loma Linda University, Loma Linda, CA, 92350, USA.
  • Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ, 85259, USA.
  • College of Chemistry, Sichuan University, Chengdu, 610064, Sichuan, China.
  • Science for Life Laboratory, Karolinska Institutet, Tomtebodavägen 23B, 171 65, Solna, Sweden.
  • National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 45 Center Drive, Bethesda, MD, 20894, USA.
  • Department of Biostatistics, Columbia Mailman School of Public Health, 722 West 168th St., New York, NY, 10032, USA.
  • Center for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
  • Clinical Laboratory, Burning Rock Biotech, Guangzhou, 510300, Guangdong, China.
  • Geneplus, PKUCare Industrial Park, Changping District, Beijing, 102206, China.
  • Genomics and Epigenetics Theme, Garvan Institute of Medical Research, Sydney, NSW, Australia.
  • Fudan-Gospel Joint Research Center for Precision Medicine, Fudan University, Shanghai, 200438, China. lemingshi@fudan.edu.cn.
  • Q2 Solutions - EA Genomics, 5927 S Miami Blvd, Morrisville, NC, 27560, USA. wendell.jones@q2labsolutions.com.
  • Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA. joshua.xu@fda.hhs.gov.
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s13059-021-02315-0

    DOI

    http://dx.doi.org/10.1186/s13059-021-02315-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1137264808

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/33863344


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    22 schema:description BACKGROUND: Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-led SEquence Quality Control project phase2 (SEQC2) effort, we perform a cross-platform multi-lab evaluation of eight Pan-Cancer panels to assess best practices for oncopanel sequencing. RESULTS: All panels demonstrate high sensitivity across targeted high-confidence coding regions and variant types for the variants previously verified to have variant allele frequency (VAF) in the 5-20% range. Sensitivity is reduced by utilizing VAF thresholds due to inherent variability in VAF measurements. Enforcing a VAF threshold for reporting has a positive impact on reducing false positive calls. Importantly, the false positive rate is found to be significantly higher outside the high-confidence coding regions, resulting in lower reproducibility. Thus, region restriction and VAF thresholds lead to low relative technical variability in estimating promising biomarkers and tumor mutational burden. CONCLUSION: This comprehensive study provides actionable guidelines for oncopanel sequencing and clear evidence that supports a simplified approach to assess the analytical performance of oncopanels. It will facilitate the rapid implementation, validation, and quality control of oncopanels in clinical use.
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