High-performance web services for querying gene and variant annotation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Jiwen Xin, Adam Mark, Cyrus Afrasiabi, Ginger Tsueng, Moritz Juchler, Nikhil Gopal, Gregory S. Stupp, Timothy E. Putman, Benjamin J. Ainscough, Obi L. Griffith, Ali Torkamani, Patricia L. Whetzel, Christopher J. Mungall, Sean D. Mooney, Andrew I. Su, Chunlei Wu

ABSTRACT

Efficient tools for data management and integration are essential for many aspects of high-throughput biology. In particular, annotations of genes and human genetic variants are commonly used but highly fragmented across many resources. Here, we describe MyGene.info and MyVariant.info, high-performance web services for querying gene and variant annotation information. These web services are currently accessed more than three million times permonth. They also demonstrate a generalizable cloud-based model for organizing and querying biological annotation information. MyGene.info and MyVariant.info are provided as high-performance web services, accessible at http://mygene.info and http://myvariant.info . Both are offered free of charge to the research community. More... »

PAGES

91

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13059-016-0953-9

DOI

http://dx.doi.org/10.1186/s13059-016-0953-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003299076

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27154141


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