COVID-19: ICU delirium management during SARS-CoV-2 pandemic View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-04-28

AUTHORS

Katarzyna Kotfis, Shawniqua Williams Roberson, Jo Ellen Wilson, Wojciech Dabrowski, Brenda T. Pun, E. Wesley Ely

ABSTRACT

The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delirium, a dangerous untoward prognostic development, serves as a barometer of systemic injury in critical illness. The early reports of 25% encephalopathy from China are likely a gross underestimation, which we know occurs whenever delirium is not monitored with a valid tool. Indeed, patients with COVID-19 are at accelerated risk for delirium due to at least seven factors including (1) direct central nervous system (CNS) invasion, (2) induction of CNS inflammatory mediators, (3) secondary effect of other organ system failure, (4) effect of sedative strategies, (5) prolonged mechanical ventilation time, (6) immobilization, and (7) other needed but unfortunate environmental factors including social isolation and quarantine without family. Given early insights into the pathobiology of the virus, as well as the emerging interventions utilized to treat the critically ill patients, delirium prevention and management will prove exceedingly challenging, especially in the intensive care unit (ICU). The main focus during the COVID-19 pandemic lies within organizational issues, i.e., lack of ventilators, shortage of personal protection equipment, resource allocation, prioritization of limited mechanical ventilation options, and end-of-life care. However, the standard of care for ICU patients, including delirium management, must remain the highest quality possible with an eye towards long-term survival and minimization of issues related to post-intensive care syndrome (PICS). This article discusses how ICU professionals (e.g., physicians, nurses, physiotherapists, pharmacologists) can use our knowledge and resources to limit the burden of delirium on patients by reducing modifiable risk factors despite the imposed heavy workload and difficult clinical challenges posed by the pandemic. More... »

PAGES

176

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13054-020-02882-x

DOI

http://dx.doi.org/10.1186/s13054-020-02882-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1127125001

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32345343


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Betacoronavirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "COVID-19", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coronavirus Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Delirium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intensive Care Units", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pandemics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pneumonia, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "SARS-CoV-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Safety", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Al. Powsta\u0144c\u00f3w Wielkopolskich 72, 70-111, Szczecin, Poland", 
          "id": "http://www.grid.ac/institutes/grid.107950.a", 
          "name": [
            "Department Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Al. Powsta\u0144c\u00f3w Wielkopolskich 72, 70-111, Szczecin, Poland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kotfis", 
        "givenName": "Katarzyna", 
        "id": "sg:person.0641005233.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641005233.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Bioengineering, Vanderbilt University, Nashville, TN, USA", 
          "id": "http://www.grid.ac/institutes/grid.152326.1", 
          "name": [
            "Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA", 
            "Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA", 
            "Department of Bioengineering, Vanderbilt University, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Williams Roberson", 
        "givenName": "Shawniqua", 
        "id": "sg:person.016662453401.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016662453401.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA", 
            "Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA", 
            "Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilson", 
        "givenName": "Jo Ellen", 
        "id": "sg:person.0775220124.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775220124.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Lublin, Poland", 
          "id": "http://www.grid.ac/institutes/grid.411484.c", 
          "name": [
            "Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Lublin, Poland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dabrowski", 
        "givenName": "Wojciech", 
        "id": "sg:person.0740246002.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740246002.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA", 
          "id": "http://www.grid.ac/institutes/grid.412807.8", 
          "name": [
            "Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pun", 
        "givenName": "Brenda T.", 
        "id": "sg:person.01262247752.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262247752.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA", 
          "id": "http://www.grid.ac/institutes/grid.412807.8", 
          "name": [
            "Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA", 
            "Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA", 
            "Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ely", 
        "givenName": "E. Wesley", 
        "id": "sg:person.012337030037.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012337030037.37"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-1-4615-2996-5_52", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027815456", 
          "https://doi.org/10.1007/978-1-4615-2996-5_52"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1466-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036837193", 
          "https://doi.org/10.1007/s00134-009-1466-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro1343", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009617803", 
          "https://doi.org/10.1038/nrmicro1343"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-016-4297-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033593025", 
          "https://doi.org/10.1007/s00134-016-4297-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc11407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034318239", 
          "https://doi.org/10.1186/cc11407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001340100909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027303695", 
          "https://doi.org/10.1007/s001340100909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40560-016-0145-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038512488", 
          "https://doi.org/10.1186/s40560-016-0145-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-001-1132-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010248409", 
          "https://doi.org/10.1007/s00134-001-1132-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1757-7241-22-19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051503983", 
          "https://doi.org/10.1186/1757-7241-22-19"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep14235", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003108804", 
          "https://doi.org/10.1038/srep14235"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-04-28", 
    "datePublishedReg": "2020-04-28", 
    "description": "The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delirium, a dangerous untoward prognostic development, serves as a barometer of systemic injury in critical illness. The early reports of 25% encephalopathy from China are likely a gross underestimation, which we know occurs whenever delirium is not monitored with a valid tool. Indeed, patients with COVID-19 are at accelerated risk for delirium due to at least seven factors including (1) direct central nervous system (CNS) invasion, (2) induction of CNS inflammatory mediators, (3) secondary effect of other organ system failure, (4) effect of sedative strategies, (5) prolonged mechanical ventilation time, (6) immobilization, and (7) other needed but unfortunate environmental factors including social isolation and quarantine without family. Given early insights into the pathobiology of the virus, as well as the emerging interventions utilized to treat the critically ill patients, delirium prevention and management will prove exceedingly challenging, especially in the intensive care unit (ICU). The main focus during the COVID-19 pandemic lies within organizational issues, i.e., lack of ventilators, shortage of personal protection equipment, resource allocation, prioritization of limited mechanical ventilation options, and end-of-life care. However, the standard of care for ICU patients, including delirium management, must remain the highest quality possible with an eye towards long-term survival and minimization of issues related to post-intensive care syndrome (PICS). This article discusses how ICU professionals (e.g., physicians, nurses, physiotherapists, pharmacologists) can use our knowledge and resources to limit the burden of delirium on patients by reducing modifiable risk factors despite the imposed heavy workload and difficult clinical challenges posed by the pandemic.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s13054-020-02882-x", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.8472681", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.8472945", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6810173", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6541030", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1117766", 
        "issn": [
          "1364-8535", 
          "1466-609X"
        ], 
        "name": "Critical Care", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "24"
      }
    ], 
    "keywords": [
      "post-intensive care syndrome", 
      "intensive care unit", 
      "delirium management", 
      "direct central nervous system invasion", 
      "central nervous system invasion", 
      "nervous system invasion", 
      "burden of delirium", 
      "ICU delirium management", 
      "mechanical ventilation time", 
      "organ system failure", 
      "modifiable risk factors", 
      "difficult clinical challenge", 
      "standard of care", 
      "coronavirus disease-19", 
      "SARS-CoV-2 pandemic", 
      "long-term survival", 
      "lack of ventilators", 
      "public health threat", 
      "World Health Organization", 
      "sedative strategy", 
      "delirium prevention", 
      "critical illness", 
      "systemic injury", 
      "inflammatory mediators", 
      "ill patients", 
      "ICU patients", 
      "system invasion", 
      "care unit", 
      "ventilation time", 
      "risk factors", 
      "disease-19", 
      "personal protection equipment", 
      "clinical challenge", 
      "life care", 
      "ICU professionals", 
      "delirium", 
      "patients", 
      "Health Organization", 
      "health threat", 
      "novel coronavirus", 
      "COVID-19", 
      "social isolation", 
      "valid tool", 
      "care", 
      "earlier reports", 
      "ventilation options", 
      "pandemic", 
      "secondary effects", 
      "prognostic developments", 
      "syndrome", 
      "injury", 
      "illness", 
      "management", 
      "protection equipment", 
      "factors", 
      "ventilator", 
      "pathobiology", 
      "environmental factors", 
      "heavy workload", 
      "prevention", 
      "survival", 
      "intervention", 
      "virus", 
      "eyes", 
      "burden", 
      "risk", 
      "mediators", 
      "coronavirus", 
      "invasion", 
      "induction", 
      "report", 
      "effect", 
      "failure", 
      "options", 
      "professionals", 
      "quarantine", 
      "gross underestimation", 
      "early insights", 
      "lack", 
      "family", 
      "isolation", 
      "quality", 
      "system failure", 
      "development", 
      "strategies", 
      "high quality", 
      "knowledge", 
      "units", 
      "standards", 
      "time", 
      "organizational issues", 
      "end", 
      "underestimation", 
      "workload", 
      "shortage", 
      "focus", 
      "challenges", 
      "tool", 
      "issues", 
      "prioritization", 
      "insights", 
      "immobilization", 
      "article", 
      "main focus", 
      "threat", 
      "organization", 
      "China", 
      "resource allocation", 
      "equipment", 
      "resources", 
      "allocation", 
      "barometer", 
      "lies", 
      "minimization"
    ], 
    "name": "COVID-19: ICU delirium management during SARS-CoV-2 pandemic", 
    "pagination": "176", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1127125001"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13054-020-02882-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "32345343"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13054-020-02882-x", 
      "https://app.dimensions.ai/details/publication/pub.1127125001"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_842.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s13054-020-02882-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13054-020-02882-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13054-020-02882-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13054-020-02882-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13054-020-02882-x'


 

This table displays all metadata directly associated to this object as RDF triples.

321 TRIPLES      21 PREDICATES      159 URIs      140 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13054-020-02882-x schema:about N45e55712b34f4862a195233d77eabb2b
2 N4879a0c4214243b9bfa994cadbc1a921
3 N853c435880394a90967b0f0c47db9d36
4 N8d74b082c8dd4353ae5d7ff90d3df255
5 N8fe362ba68474125b139ab8a0593fd09
6 N9509022774d948b9916c20a1994572ea
7 Na05639d19ae24c8d9e84521a91958ea9
8 Na9bd59220cee409baff963f0bb2ec04d
9 Ncd83dea02f8d4e41a7e8977c8d0ff298
10 Nd3a64a0757c84b089be962b60fdb3a18
11 anzsrc-for:11
12 anzsrc-for:1103
13 anzsrc-for:1117
14 schema:author N3aaf03b12af14ffdbc2b4f97bcfb2727
15 schema:citation sg:pub.10.1007/978-1-4615-2996-5_52
16 sg:pub.10.1007/s00134-001-1132-2
17 sg:pub.10.1007/s00134-009-1466-8
18 sg:pub.10.1007/s00134-016-4297-4
19 sg:pub.10.1007/s001340100909
20 sg:pub.10.1038/nrmicro1343
21 sg:pub.10.1038/srep14235
22 sg:pub.10.1186/1757-7241-22-19
23 sg:pub.10.1186/cc11407
24 sg:pub.10.1186/s40560-016-0145-4
25 schema:datePublished 2020-04-28
26 schema:datePublishedReg 2020-04-28
27 schema:description The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delirium, a dangerous untoward prognostic development, serves as a barometer of systemic injury in critical illness. The early reports of 25% encephalopathy from China are likely a gross underestimation, which we know occurs whenever delirium is not monitored with a valid tool. Indeed, patients with COVID-19 are at accelerated risk for delirium due to at least seven factors including (1) direct central nervous system (CNS) invasion, (2) induction of CNS inflammatory mediators, (3) secondary effect of other organ system failure, (4) effect of sedative strategies, (5) prolonged mechanical ventilation time, (6) immobilization, and (7) other needed but unfortunate environmental factors including social isolation and quarantine without family. Given early insights into the pathobiology of the virus, as well as the emerging interventions utilized to treat the critically ill patients, delirium prevention and management will prove exceedingly challenging, especially in the intensive care unit (ICU). The main focus during the COVID-19 pandemic lies within organizational issues, i.e., lack of ventilators, shortage of personal protection equipment, resource allocation, prioritization of limited mechanical ventilation options, and end-of-life care. However, the standard of care for ICU patients, including delirium management, must remain the highest quality possible with an eye towards long-term survival and minimization of issues related to post-intensive care syndrome (PICS). This article discusses how ICU professionals (e.g., physicians, nurses, physiotherapists, pharmacologists) can use our knowledge and resources to limit the burden of delirium on patients by reducing modifiable risk factors despite the imposed heavy workload and difficult clinical challenges posed by the pandemic.
28 schema:genre article
29 schema:isAccessibleForFree true
30 schema:isPartOf N0b55b67d5dcc400f8e8d8f1f65d33947
31 N944cd50148384bbe923e399e035bca4b
32 sg:journal.1117766
33 schema:keywords COVID-19
34 China
35 Health Organization
36 ICU delirium management
37 ICU patients
38 ICU professionals
39 SARS-CoV-2 pandemic
40 World Health Organization
41 allocation
42 article
43 barometer
44 burden
45 burden of delirium
46 care
47 care unit
48 central nervous system invasion
49 challenges
50 clinical challenge
51 coronavirus
52 coronavirus disease-19
53 critical illness
54 delirium
55 delirium management
56 delirium prevention
57 development
58 difficult clinical challenge
59 direct central nervous system invasion
60 disease-19
61 earlier reports
62 early insights
63 effect
64 end
65 environmental factors
66 equipment
67 eyes
68 factors
69 failure
70 family
71 focus
72 gross underestimation
73 health threat
74 heavy workload
75 high quality
76 ill patients
77 illness
78 immobilization
79 induction
80 inflammatory mediators
81 injury
82 insights
83 intensive care unit
84 intervention
85 invasion
86 isolation
87 issues
88 knowledge
89 lack
90 lack of ventilators
91 lies
92 life care
93 long-term survival
94 main focus
95 management
96 mechanical ventilation time
97 mediators
98 minimization
99 modifiable risk factors
100 nervous system invasion
101 novel coronavirus
102 options
103 organ system failure
104 organization
105 organizational issues
106 pandemic
107 pathobiology
108 patients
109 personal protection equipment
110 post-intensive care syndrome
111 prevention
112 prioritization
113 professionals
114 prognostic developments
115 protection equipment
116 public health threat
117 quality
118 quarantine
119 report
120 resource allocation
121 resources
122 risk
123 risk factors
124 secondary effects
125 sedative strategy
126 shortage
127 social isolation
128 standard of care
129 standards
130 strategies
131 survival
132 syndrome
133 system failure
134 system invasion
135 systemic injury
136 threat
137 time
138 tool
139 underestimation
140 units
141 valid tool
142 ventilation options
143 ventilation time
144 ventilator
145 virus
146 workload
147 schema:name COVID-19: ICU delirium management during SARS-CoV-2 pandemic
148 schema:pagination 176
149 schema:productId N0ef901b4a3ce49e59c9b400221d48ad2
150 N413210a3677140fdad97cc125d623c4c
151 N6577160238694d3ea3d9d31e4aaa9c49
152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1127125001
153 https://doi.org/10.1186/s13054-020-02882-x
154 schema:sdDatePublished 2022-09-02T16:05
155 schema:sdLicense https://scigraph.springernature.com/explorer/license/
156 schema:sdPublisher Nfbcab87140dc4a62a3987d00d8db1fd3
157 schema:url https://doi.org/10.1186/s13054-020-02882-x
158 sgo:license sg:explorer/license/
159 sgo:sdDataset articles
160 rdf:type schema:ScholarlyArticle
161 N0b55b67d5dcc400f8e8d8f1f65d33947 schema:volumeNumber 24
162 rdf:type schema:PublicationVolume
163 N0ef901b4a3ce49e59c9b400221d48ad2 schema:name dimensions_id
164 schema:value pub.1127125001
165 rdf:type schema:PropertyValue
166 N3aaf03b12af14ffdbc2b4f97bcfb2727 rdf:first sg:person.0641005233.07
167 rdf:rest Nf192360d3631440db69bc6c9494b2905
168 N413210a3677140fdad97cc125d623c4c schema:name doi
169 schema:value 10.1186/s13054-020-02882-x
170 rdf:type schema:PropertyValue
171 N45e55712b34f4862a195233d77eabb2b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Pneumonia, Viral
173 rdf:type schema:DefinedTerm
174 N4879a0c4214243b9bfa994cadbc1a921 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Betacoronavirus
176 rdf:type schema:DefinedTerm
177 N6577160238694d3ea3d9d31e4aaa9c49 schema:name pubmed_id
178 schema:value 32345343
179 rdf:type schema:PropertyValue
180 N7ae97a07e8d648d2a93ff7b6755dac76 rdf:first sg:person.012337030037.37
181 rdf:rest rdf:nil
182 N853c435880394a90967b0f0c47db9d36 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name SARS-CoV-2
184 rdf:type schema:DefinedTerm
185 N8d74b082c8dd4353ae5d7ff90d3df255 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Pandemics
187 rdf:type schema:DefinedTerm
188 N8fe362ba68474125b139ab8a0593fd09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name COVID-19
190 rdf:type schema:DefinedTerm
191 N944cd50148384bbe923e399e035bca4b schema:issueNumber 1
192 rdf:type schema:PublicationIssue
193 N9509022774d948b9916c20a1994572ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Safety
195 rdf:type schema:DefinedTerm
196 Na05639d19ae24c8d9e84521a91958ea9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Humans
198 rdf:type schema:DefinedTerm
199 Na9bd59220cee409baff963f0bb2ec04d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Coronavirus Infections
201 rdf:type schema:DefinedTerm
202 Ncd83dea02f8d4e41a7e8977c8d0ff298 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Intensive Care Units
204 rdf:type schema:DefinedTerm
205 Nd3a64a0757c84b089be962b60fdb3a18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Delirium
207 rdf:type schema:DefinedTerm
208 Nd6826f37f0354d6d9e291905a2943810 rdf:first sg:person.0775220124.17
209 rdf:rest Nd92e0ccfb0414848a3e192a251eb0761
210 Nd92e0ccfb0414848a3e192a251eb0761 rdf:first sg:person.0740246002.11
211 rdf:rest Nf90d49a1e2264934ae7a1a577dee9f69
212 Nf192360d3631440db69bc6c9494b2905 rdf:first sg:person.016662453401.43
213 rdf:rest Nd6826f37f0354d6d9e291905a2943810
214 Nf90d49a1e2264934ae7a1a577dee9f69 rdf:first sg:person.01262247752.42
215 rdf:rest N7ae97a07e8d648d2a93ff7b6755dac76
216 Nfbcab87140dc4a62a3987d00d8db1fd3 schema:name Springer Nature - SN SciGraph project
217 rdf:type schema:Organization
218 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
219 schema:name Medical and Health Sciences
220 rdf:type schema:DefinedTerm
221 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
222 schema:name Clinical Sciences
223 rdf:type schema:DefinedTerm
224 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
225 schema:name Public Health and Health Services
226 rdf:type schema:DefinedTerm
227 sg:grant.6541030 http://pending.schema.org/fundedItem sg:pub.10.1186/s13054-020-02882-x
228 rdf:type schema:MonetaryGrant
229 sg:grant.6810173 http://pending.schema.org/fundedItem sg:pub.10.1186/s13054-020-02882-x
230 rdf:type schema:MonetaryGrant
231 sg:grant.8472681 http://pending.schema.org/fundedItem sg:pub.10.1186/s13054-020-02882-x
232 rdf:type schema:MonetaryGrant
233 sg:grant.8472945 http://pending.schema.org/fundedItem sg:pub.10.1186/s13054-020-02882-x
234 rdf:type schema:MonetaryGrant
235 sg:journal.1117766 schema:issn 1364-8535
236 1466-609X
237 schema:name Critical Care
238 schema:publisher Springer Nature
239 rdf:type schema:Periodical
240 sg:person.012337030037.37 schema:affiliation grid-institutes:grid.412807.8
241 schema:familyName Ely
242 schema:givenName E. Wesley
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012337030037.37
244 rdf:type schema:Person
245 sg:person.01262247752.42 schema:affiliation grid-institutes:grid.412807.8
246 schema:familyName Pun
247 schema:givenName Brenda T.
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262247752.42
249 rdf:type schema:Person
250 sg:person.016662453401.43 schema:affiliation grid-institutes:grid.152326.1
251 schema:familyName Williams Roberson
252 schema:givenName Shawniqua
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016662453401.43
254 rdf:type schema:Person
255 sg:person.0641005233.07 schema:affiliation grid-institutes:grid.107950.a
256 schema:familyName Kotfis
257 schema:givenName Katarzyna
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641005233.07
259 rdf:type schema:Person
260 sg:person.0740246002.11 schema:affiliation grid-institutes:grid.411484.c
261 schema:familyName Dabrowski
262 schema:givenName Wojciech
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740246002.11
264 rdf:type schema:Person
265 sg:person.0775220124.17 schema:affiliation grid-institutes:None
266 schema:familyName Wilson
267 schema:givenName Jo Ellen
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775220124.17
269 rdf:type schema:Person
270 sg:pub.10.1007/978-1-4615-2996-5_52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027815456
271 https://doi.org/10.1007/978-1-4615-2996-5_52
272 rdf:type schema:CreativeWork
273 sg:pub.10.1007/s00134-001-1132-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010248409
274 https://doi.org/10.1007/s00134-001-1132-2
275 rdf:type schema:CreativeWork
276 sg:pub.10.1007/s00134-009-1466-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036837193
277 https://doi.org/10.1007/s00134-009-1466-8
278 rdf:type schema:CreativeWork
279 sg:pub.10.1007/s00134-016-4297-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033593025
280 https://doi.org/10.1007/s00134-016-4297-4
281 rdf:type schema:CreativeWork
282 sg:pub.10.1007/s001340100909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027303695
283 https://doi.org/10.1007/s001340100909
284 rdf:type schema:CreativeWork
285 sg:pub.10.1038/nrmicro1343 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009617803
286 https://doi.org/10.1038/nrmicro1343
287 rdf:type schema:CreativeWork
288 sg:pub.10.1038/srep14235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003108804
289 https://doi.org/10.1038/srep14235
290 rdf:type schema:CreativeWork
291 sg:pub.10.1186/1757-7241-22-19 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051503983
292 https://doi.org/10.1186/1757-7241-22-19
293 rdf:type schema:CreativeWork
294 sg:pub.10.1186/cc11407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034318239
295 https://doi.org/10.1186/cc11407
296 rdf:type schema:CreativeWork
297 sg:pub.10.1186/s40560-016-0145-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038512488
298 https://doi.org/10.1186/s40560-016-0145-4
299 rdf:type schema:CreativeWork
300 grid-institutes:None schema:alternateName Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA
301 schema:name Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA
302 Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA
303 Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA
304 rdf:type schema:Organization
305 grid-institutes:grid.107950.a schema:alternateName Department Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Al. Powstańców Wielkopolskich 72, 70-111, Szczecin, Poland
306 schema:name Department Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Al. Powstańców Wielkopolskich 72, 70-111, Szczecin, Poland
307 rdf:type schema:Organization
308 grid-institutes:grid.152326.1 schema:alternateName Department of Bioengineering, Vanderbilt University, Nashville, TN, USA
309 schema:name Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA
310 Department of Bioengineering, Vanderbilt University, Nashville, TN, USA
311 Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
312 rdf:type schema:Organization
313 grid-institutes:grid.411484.c schema:alternateName Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Lublin, Poland
314 schema:name Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Lublin, Poland
315 rdf:type schema:Organization
316 grid-institutes:grid.412807.8 schema:alternateName Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA
317 Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
318 schema:name Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA
319 Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
320 Geriatric Research, Education and Clinical Center (GRECC), Tennessee Valley Veterans Affairs Healthcare System, Nashville, TN, USA
321 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...