Advancing the science of organ donor management View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Sonny Dhanani, Sam D Shemie

ABSTRACT

There is an increasing burden of responsibility for intensivists to optimize donation potential after the declaration of brain death in patients with catastrophic brain injury. Best practice for donor management, if present, has been formed on low quality and mainly observational studies or consensus. In particular, research into the use of corticosteroids has shown varied benefit. The specific and limited results of the CORTICOME study are less important than the systematic methodology and the development of rigour in the study of deceased organ donation. Donor management would benefit from continued systematic analysis of current literature, understanding of the physiologic basis for therapy, and further prospective controlled trials. Worldwide collaboration partnerships and funding are needed to optimize the management of deceased organ donation. More... »

PAGES

612

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13054-014-0612-z

DOI

http://dx.doi.org/10.1186/s13054-014-0612-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047675185

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25672523


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