Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-03-07

AUTHORS

Michele Miraglia Del Giudice, Cristiana Indolfi, Michele Capasso, Nunzia Maiello, Fabio Decimo, Giorgio Ciprandi

ABSTRACT

BackgroundAllergic rhinitis (AR) and allergic asthma are caused by an IgE-mediated inflammatory reaction. Probiotics may exert anti-inflammatory and immune-modulatory activity. Thus, this study aimed at investigating whether a Bifidobacteria mixture could be able to relieve nasal symptoms, and affect quality of life (QoL) in children with AR and intermittent asthma due to Parietaria allergy.Materials and methodsThe present study was conducted as placebo-controlled, double-blinded, and randomized. Globally, 40 children (18 males; mean age 9 ± 2.2 years) were enrolled. They were treated with probiotics or placebo: 1 sachet/day for 4 weeks. AR symptoms, and QoL were assessed at baseline and after treatment. Use of rescue medications, such as cetirizine syrup and salbutamol spray, was also permitted and recorded.ResultsChildren treated with probiotic mixture achieved a significant improvement of symptoms (p < 0.005), and QoL ((p < 0.001). Placebo group had worsening of symptoms (p < 0.005) and QoL (p < 0.001). The use of rescue medications was overlapping in the two groups. The intergroup analysis showed that probiotic mixture was significantly superior than placebo for all parameters.ConclusionsThe current study demonstrated that a Bifidobacteria mixture was able of significantly improving AR symptoms and QoL in children with pollen-induced AR and intermittent asthma.Clinical trial registrationClinicalTrials.gov ID NCT02807064. More... »

PAGES

25

Journal

TITLE

Italian Journal of Pediatrics

ISSUE

1

VOLUME

43

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13052-017-0340-5

DOI

http://dx.doi.org/10.1186/s13052-017-0340-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084251955

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28270216


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Administration, Oral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Asthma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bifidobacterium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Double-Blind Method", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Combinations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Probiotics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Function Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rhinitis, Allergic, Seasonal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy", 
          "id": "http://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miraglia Del Giudice", 
        "givenName": "Michele", 
        "id": "sg:person.013352112574.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013352112574.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy", 
          "id": "http://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Indolfi", 
        "givenName": "Cristiana", 
        "id": "sg:person.0730337622.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730337622.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Paediatrics, Ospedale Civile \u2018Ave Gratia Plena\u2019, Piedimonte Matese, CE, Italy", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Paediatrics, Ospedale Civile \u2018Ave Gratia Plena\u2019, Piedimonte Matese, CE, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Capasso", 
        "givenName": "Michele", 
        "id": "sg:person.01155617467.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155617467.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy", 
          "id": "http://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maiello", 
        "givenName": "Nunzia", 
        "id": "sg:person.0776651540.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776651540.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy", 
          "id": "http://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Decimo", 
        "givenName": "Fabio", 
        "id": "sg:person.0601273320.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601273320.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy", 
          "id": "http://www.grid.ac/institutes/grid.410345.7", 
          "name": [
            "Department of Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ciprandi", 
        "givenName": "Giorgio", 
        "id": "sg:person.01354560723.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354560723.27"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1097/wox.0b013e3181f234d4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004085430", 
          "https://doi.org/10.1097/wox.0b013e3181f234d4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3180a76d94", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001005469", 
          "https://doi.org/10.1203/pdr.0b013e3180a76d94"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1824-7288-39-47", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042265989", 
          "https://doi.org/10.1186/1824-7288-39-47"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11882-016-0606-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052886610", 
          "https://doi.org/10.1007/s11882-016-0606-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13213-014-0953-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007053012", 
          "https://doi.org/10.1007/s13213-014-0953-5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-03-07", 
    "datePublishedReg": "2017-03-07", 
    "description": "BackgroundAllergic rhinitis (AR) and allergic asthma are caused by an IgE-mediated inflammatory reaction. Probiotics may exert anti-inflammatory and immune-modulatory activity. Thus, this study aimed at investigating whether a Bifidobacteria mixture could be able to relieve nasal symptoms, and affect quality of life (QoL) in children with AR and intermittent asthma due to Parietaria allergy.Materials and methodsThe present study was conducted as placebo-controlled, double-blinded, and randomized. Globally, 40 children (18 males; mean age 9\u2009\u00b1\u20092.2\u00a0years) were enrolled. They were treated with probiotics or placebo: 1 sachet/day for 4\u00a0weeks. AR symptoms, and QoL were assessed at baseline and after treatment. Use of rescue medications, such as cetirizine syrup and salbutamol spray, was also permitted and recorded.ResultsChildren treated with probiotic mixture achieved a significant improvement of symptoms (p\u2009<\u20090.005), and QoL ((p\u2009<\u20090.001). Placebo group had worsening of symptoms (p\u2009<\u20090.005) and QoL (p\u2009<\u20090.001). The use of rescue medications was overlapping in the two groups. The intergroup analysis showed that probiotic mixture was significantly superior than placebo for all parameters.ConclusionsThe current study demonstrated that a Bifidobacteria mixture was able of significantly improving AR symptoms and QoL in children with pollen-induced AR and intermittent asthma.Clinical trial registrationClinicalTrials.gov ID NCT02807064.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s13052-017-0340-5", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1320494", 
        "issn": [
          "1720-8424", 
          "1824-7288"
        ], 
        "name": "Italian Journal of Pediatrics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "43"
      }
    ], 
    "keywords": [
      "IgE-mediated inflammatory reactions", 
      "sachets/day", 
      "immune modulatory activity", 
      "quality of life", 
      "MethodsThe present study", 
      "BackgroundAllergic rhinitis", 
      "rescue medication", 
      "cetirizine syrup", 
      "allergic asthma", 
      "nasal symptoms", 
      "intermittent asthma", 
      "AR symptoms", 
      "inflammatory reaction", 
      "salbutamol spray", 
      "probiotic mixture", 
      "Parietaria allergy", 
      "symptoms", 
      "asthma", 
      "QoL", 
      "present study", 
      "probiotics", 
      "significant improvement", 
      "children", 
      "placebo", 
      "rhinitis", 
      "medications", 
      "allergy", 
      "ResultsChildren", 
      "baseline", 
      "weeks", 
      "treatment", 
      "study", 
      "days", 
      "activity", 
      "life", 
      "syrup", 
      "improvement", 
      "use", 
      "quality", 
      "reaction", 
      "Ar", 
      "materials", 
      "spray", 
      "mixture"
    ], 
    "name": "Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma", 
    "pagination": "25", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084251955"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13052-017-0340-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28270216"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13052-017-0340-5", 
      "https://app.dimensions.ai/details/publication/pub.1084251955"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_740.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s13052-017-0340-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13052-017-0340-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13052-017-0340-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13052-017-0340-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13052-017-0340-5'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      21 PREDICATES      93 URIs      80 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13052-017-0340-5 schema:about N0b75125f68b14355a50fb2a59398ed98
2 N1c20f4a4f22342cf9d90c5842a822b59
3 N248effe23b3d402cbbdf20d541a52307
4 N56cf25bf8d5b4ba69bfdd13fc2123cae
5 N5e06885303c149cab202301976fbac91
6 N6c3db454cee24c27b6a421ccdb4a6212
7 N6e2b7a42c72e41389e0276e443f1185a
8 N70dd344080274ed386858e9d9d753a67
9 N78107a482529424f990de91c4d04254d
10 N7aeb459cbf51452cbdb1e1ad7421e8e2
11 N8a2b80cc571f47a3bca28c137a0bee5d
12 N8e4aeee3303a42b4af5903e7325fabef
13 N9101318059424f1aac62f7c68c342292
14 N9423ee1ca8604b6681ca31a87199cd8a
15 N9d911c3c326b423ba291acaddfc04b47
16 Na41299f1f86b4b478b3b18fbf1e9b7a5
17 Nb0ab1ae7ca4c4555bf2ac84350b218ef
18 Nfaae0f9de14946a9aa4026773ea63560
19 Nff5b45f966eb4e17bd9d302cbf4e5978
20 anzsrc-for:11
21 anzsrc-for:1102
22 schema:author Ndbbf04a50f6d40f7b273832cf5444543
23 schema:citation sg:pub.10.1007/s11882-016-0606-9
24 sg:pub.10.1007/s13213-014-0953-5
25 sg:pub.10.1097/wox.0b013e3181f234d4
26 sg:pub.10.1186/1824-7288-39-47
27 sg:pub.10.1203/pdr.0b013e3180a76d94
28 schema:datePublished 2017-03-07
29 schema:datePublishedReg 2017-03-07
30 schema:description BackgroundAllergic rhinitis (AR) and allergic asthma are caused by an IgE-mediated inflammatory reaction. Probiotics may exert anti-inflammatory and immune-modulatory activity. Thus, this study aimed at investigating whether a Bifidobacteria mixture could be able to relieve nasal symptoms, and affect quality of life (QoL) in children with AR and intermittent asthma due to Parietaria allergy.Materials and methodsThe present study was conducted as placebo-controlled, double-blinded, and randomized. Globally, 40 children (18 males; mean age 9 ± 2.2 years) were enrolled. They were treated with probiotics or placebo: 1 sachet/day for 4 weeks. AR symptoms, and QoL were assessed at baseline and after treatment. Use of rescue medications, such as cetirizine syrup and salbutamol spray, was also permitted and recorded.ResultsChildren treated with probiotic mixture achieved a significant improvement of symptoms (p < 0.005), and QoL ((p < 0.001). Placebo group had worsening of symptoms (p < 0.005) and QoL (p < 0.001). The use of rescue medications was overlapping in the two groups. The intergroup analysis showed that probiotic mixture was significantly superior than placebo for all parameters.ConclusionsThe current study demonstrated that a Bifidobacteria mixture was able of significantly improving AR symptoms and QoL in children with pollen-induced AR and intermittent asthma.Clinical trial registrationClinicalTrials.gov ID NCT02807064.
31 schema:genre article
32 schema:isAccessibleForFree true
33 schema:isPartOf Naf6f91a3615a4bc7ae481e7455ba39de
34 Nf3ca58931a744183b5b365be210e9bfc
35 sg:journal.1320494
36 schema:keywords AR symptoms
37 Ar
38 BackgroundAllergic rhinitis
39 IgE-mediated inflammatory reactions
40 MethodsThe present study
41 Parietaria allergy
42 QoL
43 ResultsChildren
44 activity
45 allergic asthma
46 allergy
47 asthma
48 baseline
49 cetirizine syrup
50 children
51 days
52 immune modulatory activity
53 improvement
54 inflammatory reaction
55 intermittent asthma
56 life
57 materials
58 medications
59 mixture
60 nasal symptoms
61 placebo
62 present study
63 probiotic mixture
64 probiotics
65 quality
66 quality of life
67 reaction
68 rescue medication
69 rhinitis
70 sachets/day
71 salbutamol spray
72 significant improvement
73 spray
74 study
75 symptoms
76 syrup
77 treatment
78 use
79 weeks
80 schema:name Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma
81 schema:pagination 25
82 schema:productId N25eafc9b694c4f50bf1f08d2114f1275
83 N535b8f6f1ce1421da474ca993af8c3e6
84 Nc3b832bfed8b40c597927322183c5415
85 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084251955
86 https://doi.org/10.1186/s13052-017-0340-5
87 schema:sdDatePublished 2022-12-01T06:37
88 schema:sdLicense https://scigraph.springernature.com/explorer/license/
89 schema:sdPublisher N3022dd1b2bda41d9a5feeb6f6668f5e7
90 schema:url https://doi.org/10.1186/s13052-017-0340-5
91 sgo:license sg:explorer/license/
92 sgo:sdDataset articles
93 rdf:type schema:ScholarlyArticle
94 N0b75125f68b14355a50fb2a59398ed98 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Drug Combinations
96 rdf:type schema:DefinedTerm
97 N1c20f4a4f22342cf9d90c5842a822b59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Bifidobacterium
99 rdf:type schema:DefinedTerm
100 N248effe23b3d402cbbdf20d541a52307 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Double-Blind Method
102 rdf:type schema:DefinedTerm
103 N25eafc9b694c4f50bf1f08d2114f1275 schema:name pubmed_id
104 schema:value 28270216
105 rdf:type schema:PropertyValue
106 N3022dd1b2bda41d9a5feeb6f6668f5e7 schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N3a567fe574364a57b8040b3b3b94679e rdf:first sg:person.0776651540.46
109 rdf:rest N612866403c7f42459b715cc671adfdaa
110 N535b8f6f1ce1421da474ca993af8c3e6 schema:name dimensions_id
111 schema:value pub.1084251955
112 rdf:type schema:PropertyValue
113 N56cf25bf8d5b4ba69bfdd13fc2123cae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Follow-Up Studies
115 rdf:type schema:DefinedTerm
116 N5e06885303c149cab202301976fbac91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Child
118 rdf:type schema:DefinedTerm
119 N612866403c7f42459b715cc671adfdaa rdf:first sg:person.0601273320.12
120 rdf:rest Ne34d419a74054c4bbaccaf0c55502b14
121 N6c3db454cee24c27b6a421ccdb4a6212 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Male
123 rdf:type schema:DefinedTerm
124 N6e2b7a42c72e41389e0276e443f1185a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Prospective Studies
126 rdf:type schema:DefinedTerm
127 N70dd344080274ed386858e9d9d753a67 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Female
129 rdf:type schema:DefinedTerm
130 N78107a482529424f990de91c4d04254d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Treatment Outcome
132 rdf:type schema:DefinedTerm
133 N7aeb459cbf51452cbdb1e1ad7421e8e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Administration, Oral
135 rdf:type schema:DefinedTerm
136 N8a2b80cc571f47a3bca28c137a0bee5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Adolescent
138 rdf:type schema:DefinedTerm
139 N8e4aeee3303a42b4af5903e7325fabef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Humans
141 rdf:type schema:DefinedTerm
142 N9101318059424f1aac62f7c68c342292 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Child, Preschool
144 rdf:type schema:DefinedTerm
145 N91d60911a7894ffcaad44318f2c3e5fa rdf:first sg:person.0730337622.38
146 rdf:rest Nd730fc9232044071a00c8963e577254b
147 N9423ee1ca8604b6681ca31a87199cd8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Probiotics
149 rdf:type schema:DefinedTerm
150 N9d911c3c326b423ba291acaddfc04b47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Rhinitis, Allergic, Seasonal
152 rdf:type schema:DefinedTerm
153 Na41299f1f86b4b478b3b18fbf1e9b7a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Respiratory Function Tests
155 rdf:type schema:DefinedTerm
156 Naf6f91a3615a4bc7ae481e7455ba39de schema:issueNumber 1
157 rdf:type schema:PublicationIssue
158 Nb0ab1ae7ca4c4555bf2ac84350b218ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Quality of Life
160 rdf:type schema:DefinedTerm
161 Nc3b832bfed8b40c597927322183c5415 schema:name doi
162 schema:value 10.1186/s13052-017-0340-5
163 rdf:type schema:PropertyValue
164 Nd730fc9232044071a00c8963e577254b rdf:first sg:person.01155617467.72
165 rdf:rest N3a567fe574364a57b8040b3b3b94679e
166 Ndbbf04a50f6d40f7b273832cf5444543 rdf:first sg:person.013352112574.26
167 rdf:rest N91d60911a7894ffcaad44318f2c3e5fa
168 Ne34d419a74054c4bbaccaf0c55502b14 rdf:first sg:person.01354560723.27
169 rdf:rest rdf:nil
170 Nf3ca58931a744183b5b365be210e9bfc schema:volumeNumber 43
171 rdf:type schema:PublicationVolume
172 Nfaae0f9de14946a9aa4026773ea63560 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Dose-Response Relationship, Drug
174 rdf:type schema:DefinedTerm
175 Nff5b45f966eb4e17bd9d302cbf4e5978 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Asthma
177 rdf:type schema:DefinedTerm
178 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
179 schema:name Medical and Health Sciences
180 rdf:type schema:DefinedTerm
181 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
182 schema:name Cardiorespiratory Medicine and Haematology
183 rdf:type schema:DefinedTerm
184 sg:journal.1320494 schema:issn 1720-8424
185 1824-7288
186 schema:name Italian Journal of Pediatrics
187 schema:publisher Springer Nature
188 rdf:type schema:Periodical
189 sg:person.01155617467.72 schema:affiliation grid-institutes:None
190 schema:familyName Capasso
191 schema:givenName Michele
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155617467.72
193 rdf:type schema:Person
194 sg:person.013352112574.26 schema:affiliation grid-institutes:grid.9841.4
195 schema:familyName Miraglia Del Giudice
196 schema:givenName Michele
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013352112574.26
198 rdf:type schema:Person
199 sg:person.01354560723.27 schema:affiliation grid-institutes:grid.410345.7
200 schema:familyName Ciprandi
201 schema:givenName Giorgio
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354560723.27
203 rdf:type schema:Person
204 sg:person.0601273320.12 schema:affiliation grid-institutes:grid.9841.4
205 schema:familyName Decimo
206 schema:givenName Fabio
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601273320.12
208 rdf:type schema:Person
209 sg:person.0730337622.38 schema:affiliation grid-institutes:grid.9841.4
210 schema:familyName Indolfi
211 schema:givenName Cristiana
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730337622.38
213 rdf:type schema:Person
214 sg:person.0776651540.46 schema:affiliation grid-institutes:grid.9841.4
215 schema:familyName Maiello
216 schema:givenName Nunzia
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776651540.46
218 rdf:type schema:Person
219 sg:pub.10.1007/s11882-016-0606-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052886610
220 https://doi.org/10.1007/s11882-016-0606-9
221 rdf:type schema:CreativeWork
222 sg:pub.10.1007/s13213-014-0953-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007053012
223 https://doi.org/10.1007/s13213-014-0953-5
224 rdf:type schema:CreativeWork
225 sg:pub.10.1097/wox.0b013e3181f234d4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004085430
226 https://doi.org/10.1097/wox.0b013e3181f234d4
227 rdf:type schema:CreativeWork
228 sg:pub.10.1186/1824-7288-39-47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042265989
229 https://doi.org/10.1186/1824-7288-39-47
230 rdf:type schema:CreativeWork
231 sg:pub.10.1203/pdr.0b013e3180a76d94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001005469
232 https://doi.org/10.1203/pdr.0b013e3180a76d94
233 rdf:type schema:CreativeWork
234 grid-institutes:None schema:alternateName Department of Paediatrics, Ospedale Civile ‘Ave Gratia Plena’, Piedimonte Matese, CE, Italy
235 schema:name Department of Paediatrics, Ospedale Civile ‘Ave Gratia Plena’, Piedimonte Matese, CE, Italy
236 rdf:type schema:Organization
237 grid-institutes:grid.410345.7 schema:alternateName Department of Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy
238 schema:name Department of Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy
239 rdf:type schema:Organization
240 grid-institutes:grid.9841.4 schema:alternateName Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy
241 schema:name Department of Woman, Child and General and Specialized Surgery, Second University of Naples, Naples, Italy
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...