Wide-pulse, high-frequency, low-intensity neuromuscular electrical stimulation has potential for targeted strengthening of an intrinsic foot muscle: a feasibility study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Darren C. James, Matthew C. Solan, Katya N. Mileva

ABSTRACT

Background: Strengthening the intrinsic foot muscles is a poorly understood and largely overlooked area. In this study, we explore the feasibility of strengthening m. abductor hallucis (AH) with a specific paradigm of neuromuscular electrical stimulation; one which is low-intensity in nature and designed to interleave physiologically-relevant low frequency stimulation with high-frequencies to enhance effective current delivery to spinal motoneurones, and enable a proportion of force produced by the target muscle to be generated from a central origin. We use standard neurophysiological measurements to evaluate the acute (~ 30 min) peripheral and central adaptations in healthy individuals. Methods: The AH in the dominant foot of nine healthy participants was stimulated with 24 × 15 s trains of square wave (1 ms), constant current (150% of motor threshold), alternating (20 Hz-100 Hz) neuromuscular electrical stimulation interspersed with 45 s rest. Prior to the intervention, peripheral variables were evoked from the AH compound muscle action potential (Mwave) and corresponding twitch force in response to supramaximal (130%) medial plantar nerve stimulation. Central variables were evoked from the motor evoked potential (MEP) in response to suprathreshold (150%) transcranial magnetic stimulation of the motor cortex corresponding to the AH pathway. Follow-up testing occurred immediately, and 30 min after the intervention. In addition, the force-time-integrals (FTI) from the 1st and 24th WPHF trains were analysed as an index of muscle fatigue. All variables except FTI (T-test) were entered for statistical analysis using a single factor repeated measures ANOVA with alpha set at 0.05. Results: FTI was significantly lower at the end of the electrical intervention compared to that evoked by the first train (p < 0.01). Only significant peripheral nervous system adaptations were observed, consistent with the onset of low-frequency fatigue in the muscle. In most of these variables, the effects persisted for 30 min after the intervention. Conclusions: An acute session of wide-pulse, high-frequency, low-intensity electrical stimulation delivered directly to abductor hallucis in healthy feet induces muscle fatigue via adaptations at the peripheral level of the neuromuscular system. Our findings would appear to represent the first step in muscle adaptation to training; therefore, there is potential for using WPHF for intrinsic foot muscle strengthening. More... »

PAGES

16

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13047-018-0258-1

DOI

http://dx.doi.org/10.1186/s13047-018-0258-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103788616

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29755590


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adaptation, Physiological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Electric Stimulation Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Electromyography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Evoked Potentials, Motor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Feasibility Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Foot", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Fatigue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Strength", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle, Skeletal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuromuscular Junction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tibial Nerve", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "London South Bank University", 
          "id": "https://www.grid.ac/institutes/grid.4756.0", 
          "name": [
            "Sport & Exercise Science Research Centre, School of Applied Sciences, London South Bank University, 103 Borough Road, SE1 0AA, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "James", 
        "givenName": "Darren C.", 
        "id": "sg:person.01063427376.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063427376.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Surrey County Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416224.7", 
          "name": [
            "Department of Trauma and Orthopaedic Surgery, Royal Surrey County Hospital, Guildford, GU2 5XX, Surrey, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Solan", 
        "givenName": "Matthew C.", 
        "id": "sg:person.0723336503.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723336503.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "London South Bank University", 
          "id": "https://www.grid.ac/institutes/grid.4756.0", 
          "name": [
            "Sport & Exercise Science Research Centre, School of Applied Sciences, London South Bank University, 103 Borough Road, SE1 0AA, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mileva", 
        "givenName": "Katya N.", 
        "id": "sg:person.01046156743.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046156743.15"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00221-011-2556-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000410311", 
          "https://doi.org/10.1007/s00221-011-2556-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neulet.2012.08.072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003935834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2003.038836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004975694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bjsports-2013-092690", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012721192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mus.10356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013156596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1589/jpts.27.1019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020662417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.jfas.2003.10.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022305793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107110070502600610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023566083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107110070502600610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023566083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.phm.0000064718.24109.26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023703904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.phm.0000064718.24109.26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023703904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.phm.0000064718.24109.26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023703904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-7793.2001.0871h.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024240286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.91635.2008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026152966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.01015.2013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027078911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2474-14-45", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027363579", 
          "https://doi.org/10.1186/1471-2474-14-45"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0143972", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028715805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mus.21007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028721810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4886(79)90280-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031237996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1100/tsw.2007.49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032490113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00221-010-2202-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033086562", 
          "https://doi.org/10.1007/s00221-010-2202-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00221-010-2202-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033086562", 
          "https://doi.org/10.1007/s00221-010-2202-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.math.2013.02.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033174080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jsams.2015.11.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033212828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jsams.2015.11.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033212828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1050-6411(02)00083-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033312154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1050-6411(02)00083-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033312154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fnhum.2015.00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036669049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00586-009-1246-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036681425", 
          "https://doi.org/10.1007/s00586-009-1246-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00586-009-1246-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036681425", 
          "https://doi.org/10.1007/s00586-009-1246-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00074.2011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037504683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jes.0b013e3180a0321b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039345748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jes.0b013e3180a0321b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039345748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00421-011-2087-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040826090", 
          "https://doi.org/10.1007/s00421-011-2087-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fnhum.2015.00363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041132693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1757-1146-3-21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041385760", 
          "https://doi.org/10.1186/1757-1146-3-21"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gaitpost.2014.02.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042085145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rsif.2013.1188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042307236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clinph.2012.09.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042634074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00914.2010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043019381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0077004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044512999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0185(199709)249:1<143::aid-ar17>3.0.co;2-p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045770435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2015/193741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045936170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00871.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047504201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4886(79)90279-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048288897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0032-1321893", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057270455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01630", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01630", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.h.01630", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068901244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3113/fai.2007.0617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070990450"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3113/fai.2007.0617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070990450"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ptj/86.8.1146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077276751"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "Background: Strengthening the intrinsic foot muscles is a poorly understood and largely overlooked area. In this study, we explore the feasibility of strengthening m. abductor hallucis (AH) with a specific paradigm of neuromuscular electrical stimulation; one which is low-intensity in nature and designed to interleave physiologically-relevant low frequency stimulation with high-frequencies to enhance effective current delivery to spinal motoneurones, and enable a proportion of force produced by the target muscle to be generated from a central origin. We use standard neurophysiological measurements to evaluate the acute (~\u200930\u00a0min) peripheral and central adaptations in healthy individuals.\nMethods: The AH in the dominant foot of nine healthy participants was stimulated with 24\u2009\u00d7\u200915\u00a0s trains of square wave (1\u00a0ms), constant current (150% of motor threshold), alternating (20\u00a0Hz-100\u00a0Hz) neuromuscular electrical stimulation interspersed with 45\u00a0s rest. Prior to the intervention, peripheral variables were evoked from the AH compound muscle action potential (Mwave) and corresponding twitch force in response to supramaximal (130%) medial plantar nerve stimulation. Central variables were evoked from the motor evoked potential (MEP) in response to suprathreshold (150%) transcranial magnetic stimulation of the motor cortex corresponding to the AH pathway. Follow-up testing occurred immediately, and 30\u00a0min after the intervention. In addition, the force-time-integrals (FTI) from the 1st and 24th WPHF trains were analysed as an index of muscle fatigue. All variables except FTI (T-test) were entered for statistical analysis using a single factor repeated measures ANOVA with alpha set at 0.05.\nResults: FTI was significantly lower at the end of the electrical intervention compared to that evoked by the first train (p\u00a0<\u20090.01). Only significant peripheral nervous system adaptations were observed, consistent with the onset of low-frequency fatigue in the muscle. In most of these variables, the effects persisted for 30\u00a0min after the intervention.\nConclusions: An acute session of wide-pulse, high-frequency, low-intensity electrical stimulation delivered directly to abductor hallucis in healthy feet induces muscle fatigue via adaptations at the peripheral level of the neuromuscular system. Our findings would appear to represent the first step in muscle adaptation to training; therefore, there is potential for using WPHF for intrinsic foot muscle strengthening.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s13047-018-0258-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1039920", 
        "issn": [
          "1460-7328", 
          "1757-1146"
        ], 
        "name": "Journal of Foot and Ankle Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "11"
      }
    ], 
    "name": "Wide-pulse, high-frequency, low-intensity neuromuscular electrical stimulation has potential for targeted strengthening of an intrinsic foot muscle: a feasibility study", 
    "pagination": "16", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "89b95bb2dce4ba47edc314dc907336dbdaf92e99cebc81fc6ecebac60543652a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29755590"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101471610"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s13047-018-0258-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1103788616"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s13047-018-0258-1", 
      "https://app.dimensions.ai/details/publication/pub.1103788616"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113679_00000004.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs13047-018-0258-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13047-018-0258-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13047-018-0258-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13047-018-0258-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13047-018-0258-1'


 

This table displays all metadata directly associated to this object as RDF triples.

275 TRIPLES      21 PREDICATES      85 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s13047-018-0258-1 schema:about N0f546b2e3a1347309349443600b9e38b
2 N1f42c8aaadcf4fd6bf5128d97676471a
3 N21f6c0cdb06c430e9ed63db2bf0d1a86
4 N25b5377a9f5d4849a0076858671373f2
5 N3f12a82121f243c5a25711f64463919b
6 N4f694adfb7124c3cb2f4367e1b063982
7 N5bda75ce47784d8fa4875a4be78b976b
8 N5fdbdd9f7bd54d68bbb9ee2a2dca8c23
9 N6fbe354672f445999fba6c6edef999f7
10 Naf24ea1d45f34ec5929591b1dfb9bf46
11 Nb9374de11a314eb4a54a6bf5808fb5cf
12 Nbe505431fc1647c1ac564ea08514c591
13 Ne0ce599db51f414eacc70491f6242b3b
14 Neccbc7d4aa6e4a379fa164371671dc8e
15 Nf9d77b1c54f84f59b4eb4973df865882
16 anzsrc-for:11
17 anzsrc-for:1109
18 schema:author N4be0bac59327431c8873a0b8c90aa263
19 schema:citation sg:pub.10.1007/s00221-010-2202-x
20 sg:pub.10.1007/s00221-011-2556-8
21 sg:pub.10.1007/s00421-011-2087-9
22 sg:pub.10.1007/s00586-009-1246-8
23 sg:pub.10.1186/1471-2474-14-45
24 sg:pub.10.1186/1757-1146-3-21
25 https://doi.org/10.1002/(sici)1097-0185(199709)249:1<143::aid-ar17>3.0.co;2-p
26 https://doi.org/10.1002/mus.10356
27 https://doi.org/10.1002/mus.21007
28 https://doi.org/10.1016/0014-4886(79)90279-6
29 https://doi.org/10.1016/0014-4886(79)90280-2
30 https://doi.org/10.1016/j.clinph.2012.09.022
31 https://doi.org/10.1016/j.gaitpost.2014.02.008
32 https://doi.org/10.1016/j.jsams.2015.11.004
33 https://doi.org/10.1016/j.math.2013.02.007
34 https://doi.org/10.1016/j.neulet.2012.08.072
35 https://doi.org/10.1016/s1050-6411(02)00083-4
36 https://doi.org/10.1053/j.jfas.2003.10.003
37 https://doi.org/10.1055/s-0032-1321893
38 https://doi.org/10.1093/ptj/86.8.1146
39 https://doi.org/10.1097/01.phm.0000064718.24109.26
40 https://doi.org/10.1097/jes.0b013e3180a0321b
41 https://doi.org/10.1098/rsif.2013.1188
42 https://doi.org/10.1100/tsw.2007.49
43 https://doi.org/10.1111/j.1469-7793.2001.0871h.x
44 https://doi.org/10.1113/jphysiol.2003.038836
45 https://doi.org/10.1136/bjsports-2013-092690
46 https://doi.org/10.1152/japplphysiol.00074.2011
47 https://doi.org/10.1152/japplphysiol.00871.2005
48 https://doi.org/10.1152/japplphysiol.00914.2010
49 https://doi.org/10.1152/japplphysiol.01015.2013
50 https://doi.org/10.1152/japplphysiol.91635.2008
51 https://doi.org/10.1155/2015/193741
52 https://doi.org/10.1177/107110070502600610
53 https://doi.org/10.1371/journal.pone.0077004
54 https://doi.org/10.1371/journal.pone.0143972
55 https://doi.org/10.1589/jpts.27.1019
56 https://doi.org/10.2106/jbjs.h.01630
57 https://doi.org/10.3113/fai.2007.0617
58 https://doi.org/10.3389/fnhum.2015.00001
59 https://doi.org/10.3389/fnhum.2015.00363
60 schema:datePublished 2018-12
61 schema:datePublishedReg 2018-12-01
62 schema:description Background: Strengthening the intrinsic foot muscles is a poorly understood and largely overlooked area. In this study, we explore the feasibility of strengthening m. abductor hallucis (AH) with a specific paradigm of neuromuscular electrical stimulation; one which is low-intensity in nature and designed to interleave physiologically-relevant low frequency stimulation with high-frequencies to enhance effective current delivery to spinal motoneurones, and enable a proportion of force produced by the target muscle to be generated from a central origin. We use standard neurophysiological measurements to evaluate the acute (~ 30 min) peripheral and central adaptations in healthy individuals. Methods: The AH in the dominant foot of nine healthy participants was stimulated with 24 × 15 s trains of square wave (1 ms), constant current (150% of motor threshold), alternating (20 Hz-100 Hz) neuromuscular electrical stimulation interspersed with 45 s rest. Prior to the intervention, peripheral variables were evoked from the AH compound muscle action potential (Mwave) and corresponding twitch force in response to supramaximal (130%) medial plantar nerve stimulation. Central variables were evoked from the motor evoked potential (MEP) in response to suprathreshold (150%) transcranial magnetic stimulation of the motor cortex corresponding to the AH pathway. Follow-up testing occurred immediately, and 30 min after the intervention. In addition, the force-time-integrals (FTI) from the 1st and 24th WPHF trains were analysed as an index of muscle fatigue. All variables except FTI (T-test) were entered for statistical analysis using a single factor repeated measures ANOVA with alpha set at 0.05. Results: FTI was significantly lower at the end of the electrical intervention compared to that evoked by the first train (p < 0.01). Only significant peripheral nervous system adaptations were observed, consistent with the onset of low-frequency fatigue in the muscle. In most of these variables, the effects persisted for 30 min after the intervention. Conclusions: An acute session of wide-pulse, high-frequency, low-intensity electrical stimulation delivered directly to abductor hallucis in healthy feet induces muscle fatigue via adaptations at the peripheral level of the neuromuscular system. Our findings would appear to represent the first step in muscle adaptation to training; therefore, there is potential for using WPHF for intrinsic foot muscle strengthening.
63 schema:genre research_article
64 schema:inLanguage en
65 schema:isAccessibleForFree true
66 schema:isPartOf N588a4a1edb3b481b8a9bb469dc716820
67 Nb74631a104c54bdbb0d1ebd710e02f61
68 sg:journal.1039920
69 schema:name Wide-pulse, high-frequency, low-intensity neuromuscular electrical stimulation has potential for targeted strengthening of an intrinsic foot muscle: a feasibility study
70 schema:pagination 16
71 schema:productId N0efcfad5b4c6457d8b61d3cc86a18516
72 N4a810cde667c40999752d8cbf4ac1bab
73 N691f8a85708a4f8a9e45af261e60f125
74 Nc9e3d4f52efc4846a13a09856267b91f
75 Ne402dc22d0f643e191db5ab4dde55616
76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103788616
77 https://doi.org/10.1186/s13047-018-0258-1
78 schema:sdDatePublished 2019-04-11T10:39
79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
80 schema:sdPublisher N574501ad57214581aba749dc498847ab
81 schema:url https://link.springer.com/10.1186%2Fs13047-018-0258-1
82 sgo:license sg:explorer/license/
83 sgo:sdDataset articles
84 rdf:type schema:ScholarlyArticle
85 N0efcfad5b4c6457d8b61d3cc86a18516 schema:name dimensions_id
86 schema:value pub.1103788616
87 rdf:type schema:PropertyValue
88 N0f546b2e3a1347309349443600b9e38b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Neuromuscular Junction
90 rdf:type schema:DefinedTerm
91 N1f42c8aaadcf4fd6bf5128d97676471a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Muscle, Skeletal
93 rdf:type schema:DefinedTerm
94 N21f6c0cdb06c430e9ed63db2bf0d1a86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Muscle Strength
96 rdf:type schema:DefinedTerm
97 N25b5377a9f5d4849a0076858671373f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Young Adult
99 rdf:type schema:DefinedTerm
100 N3f12a82121f243c5a25711f64463919b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Humans
102 rdf:type schema:DefinedTerm
103 N46aa54475150427b99680cb92eae83c6 rdf:first sg:person.0723336503.00
104 rdf:rest N4e71cb40a86b48faac3952aabafef2a9
105 N4a810cde667c40999752d8cbf4ac1bab schema:name pubmed_id
106 schema:value 29755590
107 rdf:type schema:PropertyValue
108 N4be0bac59327431c8873a0b8c90aa263 rdf:first sg:person.01063427376.07
109 rdf:rest N46aa54475150427b99680cb92eae83c6
110 N4e71cb40a86b48faac3952aabafef2a9 rdf:first sg:person.01046156743.15
111 rdf:rest rdf:nil
112 N4f694adfb7124c3cb2f4367e1b063982 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Tibial Nerve
114 rdf:type schema:DefinedTerm
115 N574501ad57214581aba749dc498847ab schema:name Springer Nature - SN SciGraph project
116 rdf:type schema:Organization
117 N588a4a1edb3b481b8a9bb469dc716820 schema:issueNumber 1
118 rdf:type schema:PublicationIssue
119 N5bda75ce47784d8fa4875a4be78b976b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Adaptation, Physiological
121 rdf:type schema:DefinedTerm
122 N5fdbdd9f7bd54d68bbb9ee2a2dca8c23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Feasibility Studies
124 rdf:type schema:DefinedTerm
125 N691f8a85708a4f8a9e45af261e60f125 schema:name nlm_unique_id
126 schema:value 101471610
127 rdf:type schema:PropertyValue
128 N6fbe354672f445999fba6c6edef999f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Foot
130 rdf:type schema:DefinedTerm
131 Naf24ea1d45f34ec5929591b1dfb9bf46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Evoked Potentials, Motor
133 rdf:type schema:DefinedTerm
134 Nb74631a104c54bdbb0d1ebd710e02f61 schema:volumeNumber 11
135 rdf:type schema:PublicationVolume
136 Nb9374de11a314eb4a54a6bf5808fb5cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Electromyography
138 rdf:type schema:DefinedTerm
139 Nbe505431fc1647c1ac564ea08514c591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Muscle Fatigue
141 rdf:type schema:DefinedTerm
142 Nc9e3d4f52efc4846a13a09856267b91f schema:name readcube_id
143 schema:value 89b95bb2dce4ba47edc314dc907336dbdaf92e99cebc81fc6ecebac60543652a
144 rdf:type schema:PropertyValue
145 Ne0ce599db51f414eacc70491f6242b3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Electric Stimulation Therapy
147 rdf:type schema:DefinedTerm
148 Ne402dc22d0f643e191db5ab4dde55616 schema:name doi
149 schema:value 10.1186/s13047-018-0258-1
150 rdf:type schema:PropertyValue
151 Neccbc7d4aa6e4a379fa164371671dc8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Male
153 rdf:type schema:DefinedTerm
154 Nf9d77b1c54f84f59b4eb4973df865882 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Adult
156 rdf:type schema:DefinedTerm
157 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
158 schema:name Medical and Health Sciences
159 rdf:type schema:DefinedTerm
160 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
161 schema:name Neurosciences
162 rdf:type schema:DefinedTerm
163 sg:journal.1039920 schema:issn 1460-7328
164 1757-1146
165 schema:name Journal of Foot and Ankle Research
166 rdf:type schema:Periodical
167 sg:person.01046156743.15 schema:affiliation https://www.grid.ac/institutes/grid.4756.0
168 schema:familyName Mileva
169 schema:givenName Katya N.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046156743.15
171 rdf:type schema:Person
172 sg:person.01063427376.07 schema:affiliation https://www.grid.ac/institutes/grid.4756.0
173 schema:familyName James
174 schema:givenName Darren C.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063427376.07
176 rdf:type schema:Person
177 sg:person.0723336503.00 schema:affiliation https://www.grid.ac/institutes/grid.416224.7
178 schema:familyName Solan
179 schema:givenName Matthew C.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723336503.00
181 rdf:type schema:Person
182 sg:pub.10.1007/s00221-010-2202-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033086562
183 https://doi.org/10.1007/s00221-010-2202-x
184 rdf:type schema:CreativeWork
185 sg:pub.10.1007/s00221-011-2556-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000410311
186 https://doi.org/10.1007/s00221-011-2556-8
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/s00421-011-2087-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040826090
189 https://doi.org/10.1007/s00421-011-2087-9
190 rdf:type schema:CreativeWork
191 sg:pub.10.1007/s00586-009-1246-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036681425
192 https://doi.org/10.1007/s00586-009-1246-8
193 rdf:type schema:CreativeWork
194 sg:pub.10.1186/1471-2474-14-45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027363579
195 https://doi.org/10.1186/1471-2474-14-45
196 rdf:type schema:CreativeWork
197 sg:pub.10.1186/1757-1146-3-21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041385760
198 https://doi.org/10.1186/1757-1146-3-21
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1002/(sici)1097-0185(199709)249:1<143::aid-ar17>3.0.co;2-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1045770435
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1002/mus.10356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013156596
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1002/mus.21007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028721810
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/0014-4886(79)90279-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048288897
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0014-4886(79)90280-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031237996
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.clinph.2012.09.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042634074
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/j.gaitpost.2014.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042085145
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/j.jsams.2015.11.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033212828
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/j.math.2013.02.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033174080
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/j.neulet.2012.08.072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003935834
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/s1050-6411(02)00083-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033312154
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1053/j.jfas.2003.10.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022305793
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1055/s-0032-1321893 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057270455
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1093/ptj/86.8.1146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077276751
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1097/01.phm.0000064718.24109.26 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023703904
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1097/jes.0b013e3180a0321b schema:sameAs https://app.dimensions.ai/details/publication/pub.1039345748
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1098/rsif.2013.1188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042307236
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1100/tsw.2007.49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032490113
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1111/j.1469-7793.2001.0871h.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024240286
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1113/jphysiol.2003.038836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004975694
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1136/bjsports-2013-092690 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012721192
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1152/japplphysiol.00074.2011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037504683
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1152/japplphysiol.00871.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047504201
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1152/japplphysiol.00914.2010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043019381
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1152/japplphysiol.01015.2013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027078911
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1152/japplphysiol.91635.2008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026152966
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1155/2015/193741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045936170
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1177/107110070502600610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023566083
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1371/journal.pone.0077004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044512999
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1371/journal.pone.0143972 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028715805
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1589/jpts.27.1019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020662417
261 rdf:type schema:CreativeWork
262 https://doi.org/10.2106/jbjs.h.01630 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068901244
263 rdf:type schema:CreativeWork
264 https://doi.org/10.3113/fai.2007.0617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070990450
265 rdf:type schema:CreativeWork
266 https://doi.org/10.3389/fnhum.2015.00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036669049
267 rdf:type schema:CreativeWork
268 https://doi.org/10.3389/fnhum.2015.00363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041132693
269 rdf:type schema:CreativeWork
270 https://www.grid.ac/institutes/grid.416224.7 schema:alternateName Royal Surrey County Hospital
271 schema:name Department of Trauma and Orthopaedic Surgery, Royal Surrey County Hospital, Guildford, GU2 5XX, Surrey, UK
272 rdf:type schema:Organization
273 https://www.grid.ac/institutes/grid.4756.0 schema:alternateName London South Bank University
274 schema:name Sport & Exercise Science Research Centre, School of Applied Sciences, London South Bank University, 103 Borough Road, SE1 0AA, London, UK
275 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...