Ontology type: schema:ScholarlyArticle Open Access: True
2016-12
AUTHORSPaul Kopanidis, Andrew Hardidge, Larry McNicol, Stanley Tay, Peter McCall, Laurence Weinberg
ABSTRACTBACKGROUND: Optimisation of blood management in total hip (THA) and knee arthroplasty (TKA) is associated with improved patient outcomes. This study aimed to establish the effectiveness of a perioperative blood management programme in improving postoperative haemoglobin (Hb) and reducing the rate of allogenic blood transfusion. METHODS: This retrospective before and after study involves 200 consecutive patients undergoing elective TKA and THA before (Usual Care group) and after (Intervention group) the introduction of a blood management programme in an Australian teaching hospital. Patients in the Intervention group underwent preoperative treatment for anaemia and received intraoperative tranexamic acid (15 mg/kg). The primary outcomes were to compare postoperative Hb levels and the rate of blood transfusion. Secondary outcomes included measurements of total amount of allogenic blood transfused, transfusion-related complications, postoperative complications, need for inpatient rehabilitation and duration of hospital stay. RESULTS: There were no differences between baseline characteristics between groups. The mean (SD) preoperative Hb was higher in the Intervention group compared to that in the Usual Care group: 138.7 (13.9) vs. 133.4 (13.9) g/L, p = 0.008, respectively. The postoperative day 1 Hb, lowest postoperative Hb and discharge Hb were all higher in the Intervention group (p < 0.001). Blood transfusion requirements were lower in the Intervention group compared to the Usual Care group (6 vs. 20 %, p = 0.003). There were no differences in any of the secondary outcomes measured. Patients who were anaemic preoperatively and who underwent Hb optimisation had higher Hb levels postoperatively (odds ratio 5.7; 95 % CI 1.3 to 26.5; p = 0.024). CONCLUSIONS: The introduction of a perioperative blood optimisation programme improved postoperative Hb levels and reduced the rate of allogenic blood transfusion. More... »
PAGES28
http://scigraph.springernature.com/pub.10.1186/s13018-016-0358-1
DOIhttp://dx.doi.org/10.1186/s13018-016-0358-1
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1032333239
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/26927608
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adolescent",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged, 80 and over",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Anemia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antifibrinolytic Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Arthroplasty, Replacement, Hip",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Arthroplasty, Replacement, Knee",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Blood Transfusion",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hemoglobins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Iron",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Perioperative Care",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tranexamic Acid",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Transfusion Reaction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Young Adult",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Austin Hospital",
"id": "https://www.grid.ac/institutes/grid.414094.c",
"name": [
"Department of Orthopaedic Surgery, Austin Hospital, Studley Road, 3084, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Kopanidis",
"givenName": "Paul",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Austin Hospital",
"id": "https://www.grid.ac/institutes/grid.414094.c",
"name": [
"Department of Orthopaedic Surgery, Austin Hospital, Studley Road, 3084, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Hardidge",
"givenName": "Andrew",
"id": "sg:person.0741100456.82",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741100456.82"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Austin Hospital",
"id": "https://www.grid.ac/institutes/grid.414094.c",
"name": [
"Department of Surgery, The University of Melbourne, 3010, Victoria, Australia",
"Department of Anaesthesia, Austin Hospital, Studley Road, 3084, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "McNicol",
"givenName": "Larry",
"id": "sg:person.0706560756.81",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706560756.81"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Royal Darwin Hospital",
"id": "https://www.grid.ac/institutes/grid.240634.7",
"name": [
"Department of Anaesthesia, Royal Darwin Hospital, Rocklands Drive, 0810, Tiwi, Northern Territory, Australia"
],
"type": "Organization"
},
"familyName": "Tay",
"givenName": "Stanley",
"id": "sg:person.01002340150.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002340150.40"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Austin Hospital",
"id": "https://www.grid.ac/institutes/grid.414094.c",
"name": [
"Department of Anaesthesia, Austin Hospital, Studley Road, 3084, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "McCall",
"givenName": "Peter",
"id": "sg:person.01047773775.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047773775.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Melbourne",
"id": "https://www.grid.ac/institutes/grid.1008.9",
"name": [
"Department of Surgery, The University of Melbourne, 3010, Victoria, Australia",
"Department of Anaesthesia, Austin Hospital, Studley Road, 3084, Victoria, Australia",
"Anaesthesia Perioperative Pain Medicine Unit, University of Melbourne, 3084, Victoria, Australia"
],
"type": "Organization"
},
"familyName": "Weinberg",
"givenName": "Laurence",
"id": "sg:person.0746675150.62",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746675150.62"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1111/j.1423-0410.2010.01366.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002395957"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1423-0410.2010.01366.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002395957"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/bmj.39335.541782.ad",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008007813"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1472-6963-11-135",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011131704",
"https://doi.org/10.1186/1472-6963-11-135"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1537-2995.2007.01197.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016209460"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1471-2474-10-167",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022111924",
"https://doi.org/10.1186/1471-2474-10-167"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1423-0410.2008.01108.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038544940"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ocl.2009.02.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040071245"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/trf.12332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041854223"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/bja/aen054",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042454193"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/bja/aes135",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045806882"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bcmd.2008.04.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051040184"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1302/0301-620x.93b1.24984",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064886508"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1302/0301-620x.93b12.26989",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064886574"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078710527",
"type": "CreativeWork"
}
],
"datePublished": "2016-12",
"datePublishedReg": "2016-12-01",
"description": "BACKGROUND: Optimisation of blood management in total hip (THA) and knee arthroplasty (TKA) is associated with improved patient outcomes. This study aimed to establish the effectiveness of a perioperative blood management programme in improving postoperative haemoglobin (Hb) and reducing the rate of allogenic blood transfusion.\nMETHODS: This retrospective before and after study involves 200 consecutive patients undergoing elective TKA and THA before (Usual Care group) and after (Intervention group) the introduction of a blood management programme in an Australian teaching hospital. Patients in the Intervention group underwent preoperative treatment for anaemia and received intraoperative tranexamic acid (15 mg/kg). The primary outcomes were to compare postoperative Hb levels and the rate of blood transfusion. Secondary outcomes included measurements of total amount of allogenic blood transfused, transfusion-related complications, postoperative complications, need for inpatient rehabilitation and duration of hospital stay.\nRESULTS: There were no differences between baseline characteristics between groups. The mean (SD) preoperative Hb was higher in the Intervention group compared to that in the Usual Care group: 138.7 (13.9) vs. 133.4 (13.9) g/L, p = 0.008, respectively. The postoperative day 1 Hb, lowest postoperative Hb and discharge Hb were all higher in the Intervention group (p < 0.001). Blood transfusion requirements were lower in the Intervention group compared to the Usual Care group (6 vs. 20 %, p = 0.003). There were no differences in any of the secondary outcomes measured. Patients who were anaemic preoperatively and who underwent Hb optimisation had higher Hb levels postoperatively (odds ratio 5.7; 95 % CI 1.3 to 26.5; p = 0.024).\nCONCLUSIONS: The introduction of a perioperative blood optimisation programme improved postoperative Hb levels and reduced the rate of allogenic blood transfusion.",
"genre": "research_article",
"id": "sg:pub.10.1186/s13018-016-0358-1",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1036452",
"issn": [
"1749-799X"
],
"name": "Journal of Orthopaedic Surgery and Research",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "11"
}
],
"name": "Perioperative blood management programme reduces the use of allogenic blood transfusion in patients undergoing total hip and knee arthroplasty",
"pagination": "28",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"9a077b4b56c419281c96865947dc11d104fefbb3ddb0505d5b89c4a77c1bd165"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"26927608"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101265112"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s13018-016-0358-1"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1032333239"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s13018-016-0358-1",
"https://app.dimensions.ai/details/publication/pub.1032333239"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T22:39",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000550.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1186%2Fs13018-016-0358-1"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s13018-016-0358-1'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s13018-016-0358-1'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s13018-016-0358-1'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s13018-016-0358-1'
This table displays all metadata directly associated to this object as RDF triples.
235 TRIPLES
21 PREDICATES
63 URIs
41 LITERALS
29 BLANK NODES