Driving developments in UK oesophageal radiotherapy through the SCOPE trials View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

S. Gwynne, E. Higgins, A. Poon King, G. Radhakrishna, L. Wills, S. Mukherjee, Maria Hawkins, G. Jones, J. Staffurth, T. Crosby

ABSTRACT

BACKGROUND: The SCOPE trials (SCOPE 1, NeoSCOPE and SCOPE 2) have been the backbone of oesophageal RT trials in the UK. Many changes in oesophageal RT techniques have taken place in this time. The SCOPE trials have, in addition to adopting these new techniques, been influential in aiding centres with their implementation. We discuss the progress made through the SCOPE trials and include details of a questionnaire sent to participating centres. to establish the role that trial participation played in RT changes in their centre. METHODS: Questionnaires were sent to 47 centres, 27 were returned. RESULTS: 100% of centres stated their departmental protocol for TVD was based on the relevant SCOPE trial protocol. 4DCT use has increased from 42 to 71%. Type B planning algorithms, mandated in the NeoSCOPE trial, were used in 79.9% pre NeoSCOPE and now in 83.3%. 12.5% of centres were using a stomach filling protocol pre NeoSCOPE, now risen to 50%. CBCT was mandated for IGRT in the NeoSCOPE trial. 66.7% used this routinely pre NeoSCOPE/SCOPE 2 which has risen to 87.5% in the survey. CONCLUSION: The results of the questionnaires show how participation in national oesophageal RT trials has led to the adoption of newer RT techniques in UK centres, leading to better patient care. More... »

PAGES

26

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s13014-019-1225-0

DOI

http://dx.doi.org/10.1186/s13014-019-1225-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111916252

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30717810


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