Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Qianquan Ma, Changsheng Xing, Wenyong Long, Helen Y. Wang, Qing Liu, Rong-Fu Wang

ABSTRACT

Development of central nervous system (CNS) is regulated by both intrinsic and peripheral signals. Previous studies have suggested that environmental factors affect neurological activities under both physiological and pathological conditions. Although there is anatomical separation, emerging evidence has indicated the existence of bidirectional interaction between gut microbiota, i.e., (diverse microorganisms colonizing human intestine), and brain. The cross-talk between gut microbiota and brain may have crucial impact during basic neurogenerative processes, in neurodegenerative disorders and tumors of CNS. In this review, we discuss the biological interplay between gut-brain axis, and further explore how this communication may be dysregulated in neurological diseases. Further, we highlight new insights in modification of gut microbiota composition, which may emerge as a promising therapeutic approach to treat CNS disorders. More... »

PAGES

53

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12974-019-1434-3

DOI

http://dx.doi.org/10.1186/s12974-019-1434-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112474239

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30823925


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12974-019-1434-3'


 

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