The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Joshua L. Keller, Terry J. Housh, Ethan C. Hill, Cory M. Smith, Richard J. Schmidt, Glen O. Johnson

ABSTRACT

BACKGROUND: Shilajit is a safe, fluvic mineral complex exudate that is common to Ayurvedic medicine and is composed of fulvic acids, dibenzo-α-pyrones, proteins, and minerals. The purpose of this study was to examine the effects of 8 weeks of Shilajit supplementation at 250 mg·d- 1 (low dose) and 500 mg·d- 1 (high dose) versus placebo on maximal voluntary isometric contraction (MVIC) strength, concentric peak torque, fatigue-induced percent decline in strength, and serum hydroxyproline (HYP). METHODS: Sixty-three recreationally-active men ([Formula: see text] ± SD: 21.2 ± 2.4 yr.; 179.8 ± 6.3 cm; 83.1 ± 12.7 kg) volunteered to participate in this study. The subjects were randomly assigned to the high dose, low dose, or placebo group (each group: n = 21). During pre-supplementation testing, the subjects performed 2 pretest MVICs, 2 sets of 50 maximal, bilateral, concentric isokinetic leg extensions at 180°·s- 1 separated by 2-min of rest, and 2 posttest MVICs. Following 8 weeks of supplementation, the subjects repeated the pre-supplementation testing procedures. In addition, the groups were dichotomized at the 50th percentile based on pre-supplementation MVIC and baseline HYP. Mixed model ANOVAs and ANCOVAs were used to statistically analyze the dependent variables for the total groups (n = 21 per group) as well as dichotomized groups. RESULTS: For the upper 50th percentile group, the post-supplementation adjusted mean percent decline in MVIC was significantly less for the high dose group (8.9 ± 2.3%) than the low dose (17.0 ± 2.4%; p = 0.022) and placebo (16.0 ± 2.4%; p = 0.044) groups. There was no significant (p = 0.774) difference, however, between the low dose and placebo groups. In addition, for the upper 50th percentile group, the adjusted mean post-supplementation baseline HYP for the high dose group (1.5 ± 0.3 μg·mL- 1) was significantly less than both the low dose (2.4 ± 0.3 μg·mL- 1; p = 0.034) and placebo (2.4 ± 0.3 μg·mL- 1, p = 0.024) groups. CONCLUSIONS: The results of the present study demonstrated that 8 weeks of PrimaVie® Shilajit supplementation at 500 mg·d- 1 promoted the retention of maximal muscular strength following the fatiguing protocol and decreased baseline HYP. Thus, PrimaVie® Shilajit supplementation at 500 mg·d- 1 elicited favorable muscle and connective tissue adaptations. More... »

PAGES

3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12970-019-0270-2

DOI

http://dx.doi.org/10.1186/s12970-019-0270-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111954567

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30728074


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dietary Supplements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxyproline", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isometric Contraction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Minerals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Fatigue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Strength", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle, Skeletal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Resins, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Torque", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Keller", 
        "givenName": "Joshua L.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Housh", 
        "givenName": "Terry J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hill", 
        "givenName": "Ethan C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Cory M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmidt", 
        "givenName": "Richard J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Nebraska\u2013Lincoln", 
          "id": "https://www.grid.ac/institutes/grid.24434.35", 
          "name": [
            "Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska \u2013 Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Johnson", 
        "givenName": "Glen O.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1152/japplphysiol.01174.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001089248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1037/h0076767", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001593503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0b013e31816605a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003859142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0b013e31816605a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003859142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/jsc.0b013e31816605a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003859142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00433399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004218254", 
          "https://doi.org/10.1007/bf00433399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jep.2011.04.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007707774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ptr.5018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017990657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mehy.2015.12.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019122106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12970-015-0104-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029940448", 
          "https://doi.org/10.1186/s12970-015-0104-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/00005768-199508000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032481013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/cclm.1985.23.9.515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034543638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/026404199365911", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034946125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/and.12482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036345085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2002.035089", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036697541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00007256-200434010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036869835", 
          "https://doi.org/10.2165/00007256-200434010-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00007256-200434010-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036869835", 
          "https://doi.org/10.2165/00007256-200434010-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m110709200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039390271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1748-1716.1980.tb06495.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040214471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002060-200211001-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045216961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002060-200211001-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045216961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004210050174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046019065", 
          "https://doi.org/10.1007/s004210050174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199607043350101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050135146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1519/00124278-200502000-00038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050726775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/jmf.2016.0010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051586258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-1025014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057495865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.bmb.a072570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076571174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/15438627.2011.608046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078461306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40279-017-0719-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084040158", 
          "https://doi.org/10.1007/s40279-017-0719-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40279-017-0719-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084040158", 
          "https://doi.org/10.1007/s40279-017-0719-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0043-106438", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085276892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/andr.12454", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100074721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp275450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104900296"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Shilajit is a safe, fluvic mineral complex exudate that is common to Ayurvedic medicine and is composed of fulvic acids, dibenzo-\u03b1-pyrones, proteins, and minerals. The purpose of this study was to examine the effects of 8\u2009weeks of Shilajit supplementation at 250\u2009mg\u00b7d-\u20091 (low dose) and 500\u2009mg\u00b7d-\u20091 (high dose) versus placebo on maximal voluntary isometric contraction (MVIC) strength, concentric peak torque, fatigue-induced percent decline in strength, and serum hydroxyproline (HYP).\nMETHODS: Sixty-three recreationally-active men ([Formula: see text] \u00b1 SD: 21.2\u2009\u00b1\u20092.4\u2009yr.; 179.8\u2009\u00b1\u20096.3\u2009cm; 83.1\u2009\u00b1\u200912.7\u2009kg) volunteered to participate in this study. The subjects were randomly assigned to the high dose, low dose, or placebo group (each group: n\u2009=\u200921). During pre-supplementation testing, the subjects performed 2 pretest MVICs, 2 sets of 50 maximal, bilateral, concentric isokinetic leg extensions at 180\u00b0\u00b7s-\u20091 separated by 2-min of rest, and 2 posttest MVICs. Following 8\u2009weeks of supplementation, the subjects repeated the pre-supplementation testing procedures. In addition, the groups were dichotomized at the 50th percentile based on pre-supplementation MVIC and baseline HYP. Mixed model ANOVAs and ANCOVAs were used to statistically analyze the dependent variables for the total groups (n\u2009=\u200921 per group) as well as dichotomized groups.\nRESULTS: For the upper 50th percentile group, the post-supplementation adjusted mean percent decline in MVIC was significantly less for the high dose group (8.9\u2009\u00b1\u20092.3%) than the low dose (17.0\u2009\u00b1\u20092.4%; p\u2009=\u00a00.022) and placebo (16.0\u2009\u00b1\u20092.4%; p\u2009=\u20090.044) groups. There was no significant (p\u2009=\u20090.774) difference, however, between the low dose and placebo groups. In addition, for the upper 50th percentile group, the adjusted mean post-supplementation baseline HYP for the high dose group (1.5\u2009\u00b1\u20090.3\u2009\u03bcg\u00b7mL-\u20091) was significantly less than both the low dose (2.4\u2009\u00b1\u20090.3\u2009\u03bcg\u00b7mL-\u20091; p\u2009=\u20090.034) and placebo (2.4\u2009\u00b1\u20090.3\u2009\u03bcg\u00b7mL-\u20091, p\u2009=\u20090.024) groups.\nCONCLUSIONS: The results of the present study demonstrated that 8\u2009weeks of PrimaVie\u00ae Shilajit supplementation at 500\u2009mg\u00b7d-\u20091 promoted the retention of maximal muscular strength following the fatiguing protocol and decreased baseline HYP. Thus, PrimaVie\u00ae Shilajit supplementation at 500\u2009mg\u00b7d-\u20091 elicited favorable muscle and connective tissue adaptations.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12970-019-0270-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1034609", 
        "issn": [
          "1550-2783"
        ], 
        "name": "Journal of the International Society of Sports Nutrition", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels", 
    "pagination": "3", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "dd8b05c3e6b5432db5589e75d0eb8b8f89b30a682400cbefb962bff3d121b809"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30728074"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101234168"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12970-019-0270-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111954567"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12970-019-0270-2", 
      "https://app.dimensions.ai/details/publication/pub.1111954567"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113679_00000005.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12970-019-0270-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12970-019-0270-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12970-019-0270-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12970-019-0270-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12970-019-0270-2'


 

This table displays all metadata directly associated to this object as RDF triples.

234 TRIPLES      21 PREDICATES      69 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12970-019-0270-2 schema:about N04dd561e022740d8ba60c446f9a8ce86
2 N06cc28488f634a4596ba6cca0c4555c2
3 N1bfd24cef9574de9b810088b1275be51
4 N2750c6bd9ad44435bb4cf3e45fce2631
5 N2c19e6eae3b0407a85a6bbf816ca2597
6 N30f98753b7ff432d83d1c0a53cf1fada
7 N601695078a884a89b7085465e595b39c
8 N89e4ec69a84c407891650ebf5b50aae5
9 Na81b3b83be05420f935960b5f27a3fae
10 Nac54ae92f6a44158b13bb39570999abe
11 Ne16f353c601d4356a292a1738faa17a6
12 Nef5a3b7ff5f74b12beedab4abce40b43
13 anzsrc-for:11
14 anzsrc-for:1103
15 schema:author Nf625a340bf3f4c8980128fe0402bdcd4
16 schema:citation sg:pub.10.1007/bf00433399
17 sg:pub.10.1007/s004210050174
18 sg:pub.10.1007/s40279-017-0719-x
19 sg:pub.10.1186/s12970-015-0104-9
20 sg:pub.10.2165/00007256-200434010-00005
21 https://doi.org/10.1002/ptr.5018
22 https://doi.org/10.1016/j.jep.2011.04.033
23 https://doi.org/10.1016/j.mehy.2015.12.003
24 https://doi.org/10.1037/h0076767
25 https://doi.org/10.1055/s-0043-106438
26 https://doi.org/10.1055/s-2007-1025014
27 https://doi.org/10.1056/nejm199607043350101
28 https://doi.org/10.1074/jbc.m110709200
29 https://doi.org/10.1080/026404199365911
30 https://doi.org/10.1080/15438627.2011.608046
31 https://doi.org/10.1089/jmf.2016.0010
32 https://doi.org/10.1093/oxfordjournals.bmb.a072570
33 https://doi.org/10.1097/00002060-200211001-00007
34 https://doi.org/10.1111/and.12482
35 https://doi.org/10.1111/andr.12454
36 https://doi.org/10.1111/j.1748-1716.1980.tb06495.x
37 https://doi.org/10.1113/jp275450
38 https://doi.org/10.1113/jphysiol.2002.035089
39 https://doi.org/10.1152/japplphysiol.01174.2003
40 https://doi.org/10.1249/00005768-199508000-00013
41 https://doi.org/10.1515/cclm.1985.23.9.515
42 https://doi.org/10.1519/00124278-200502000-00038
43 https://doi.org/10.1519/jsc.0b013e31816605a0
44 schema:datePublished 2019-12
45 schema:datePublishedReg 2019-12-01
46 schema:description BACKGROUND: Shilajit is a safe, fluvic mineral complex exudate that is common to Ayurvedic medicine and is composed of fulvic acids, dibenzo-α-pyrones, proteins, and minerals. The purpose of this study was to examine the effects of 8 weeks of Shilajit supplementation at 250 mg·d- 1 (low dose) and 500 mg·d- 1 (high dose) versus placebo on maximal voluntary isometric contraction (MVIC) strength, concentric peak torque, fatigue-induced percent decline in strength, and serum hydroxyproline (HYP). METHODS: Sixty-three recreationally-active men ([Formula: see text] ± SD: 21.2 ± 2.4 yr.; 179.8 ± 6.3 cm; 83.1 ± 12.7 kg) volunteered to participate in this study. The subjects were randomly assigned to the high dose, low dose, or placebo group (each group: n = 21). During pre-supplementation testing, the subjects performed 2 pretest MVICs, 2 sets of 50 maximal, bilateral, concentric isokinetic leg extensions at 180°·s- 1 separated by 2-min of rest, and 2 posttest MVICs. Following 8 weeks of supplementation, the subjects repeated the pre-supplementation testing procedures. In addition, the groups were dichotomized at the 50th percentile based on pre-supplementation MVIC and baseline HYP. Mixed model ANOVAs and ANCOVAs were used to statistically analyze the dependent variables for the total groups (n = 21 per group) as well as dichotomized groups. RESULTS: For the upper 50th percentile group, the post-supplementation adjusted mean percent decline in MVIC was significantly less for the high dose group (8.9 ± 2.3%) than the low dose (17.0 ± 2.4%; p = 0.022) and placebo (16.0 ± 2.4%; p = 0.044) groups. There was no significant (p = 0.774) difference, however, between the low dose and placebo groups. In addition, for the upper 50th percentile group, the adjusted mean post-supplementation baseline HYP for the high dose group (1.5 ± 0.3 μg·mL- 1) was significantly less than both the low dose (2.4 ± 0.3 μg·mL- 1; p = 0.034) and placebo (2.4 ± 0.3 μg·mL- 1, p = 0.024) groups. CONCLUSIONS: The results of the present study demonstrated that 8 weeks of PrimaVie® Shilajit supplementation at 500 mg·d- 1 promoted the retention of maximal muscular strength following the fatiguing protocol and decreased baseline HYP. Thus, PrimaVie® Shilajit supplementation at 500 mg·d- 1 elicited favorable muscle and connective tissue adaptations.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree true
50 schema:isPartOf N3cfe315c60c84faaa0b6c54591fbaa8f
51 N76a3cdd2043045fa9ad6a194fdf2bbfd
52 sg:journal.1034609
53 schema:name The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels
54 schema:pagination 3
55 schema:productId N0fa43300a01d4f3bb69b29d3338eda3b
56 N597e3aa4a9f244ed8037545d849dc35e
57 N5fa5d7c26c7045f48e90fc750124a6f5
58 Nad985838e9284a39bbe540898ee67eeb
59 Nd90e7cf4a0fb4ec5899df1bd94ad9ff3
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111954567
61 https://doi.org/10.1186/s12970-019-0270-2
62 schema:sdDatePublished 2019-04-11T10:39
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N40c2e348c1464fdba5d2e0be2d3e650a
65 schema:url https://link.springer.com/10.1186%2Fs12970-019-0270-2
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N04dd561e022740d8ba60c446f9a8ce86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Young Adult
71 rdf:type schema:DefinedTerm
72 N06cc28488f634a4596ba6cca0c4555c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Hydroxyproline
74 rdf:type schema:DefinedTerm
75 N0d893b1cfc2b47b8bdde4aae6272c2ab schema:affiliation https://www.grid.ac/institutes/grid.24434.35
76 schema:familyName Keller
77 schema:givenName Joshua L.
78 rdf:type schema:Person
79 N0fa43300a01d4f3bb69b29d3338eda3b schema:name doi
80 schema:value 10.1186/s12970-019-0270-2
81 rdf:type schema:PropertyValue
82 N1bfd24cef9574de9b810088b1275be51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Minerals
84 rdf:type schema:DefinedTerm
85 N2750c6bd9ad44435bb4cf3e45fce2631 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Muscle Strength
87 rdf:type schema:DefinedTerm
88 N2c19e6eae3b0407a85a6bbf816ca2597 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Torque
90 rdf:type schema:DefinedTerm
91 N30f98753b7ff432d83d1c0a53cf1fada schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Humans
93 rdf:type schema:DefinedTerm
94 N3531228b9a68472d96caaa876a8098df rdf:first N981a7a2a962943d5adc9310205d9a80b
95 rdf:rest rdf:nil
96 N3cfe315c60c84faaa0b6c54591fbaa8f schema:volumeNumber 16
97 rdf:type schema:PublicationVolume
98 N3e74688fd5114e20bba8ef3c23ba0b7e schema:affiliation https://www.grid.ac/institutes/grid.24434.35
99 schema:familyName Schmidt
100 schema:givenName Richard J.
101 rdf:type schema:Person
102 N40c2e348c1464fdba5d2e0be2d3e650a schema:name Springer Nature - SN SciGraph project
103 rdf:type schema:Organization
104 N49b9b1cc128445a08c530cdf398178a0 rdf:first N68f9188d32a64925ac4b230397bd5799
105 rdf:rest N909dacb08bec4c769b59956f8dd46a94
106 N597e3aa4a9f244ed8037545d849dc35e schema:name nlm_unique_id
107 schema:value 101234168
108 rdf:type schema:PropertyValue
109 N5fa5d7c26c7045f48e90fc750124a6f5 schema:name dimensions_id
110 schema:value pub.1111954567
111 rdf:type schema:PropertyValue
112 N601695078a884a89b7085465e595b39c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Muscle, Skeletal
114 rdf:type schema:DefinedTerm
115 N68f9188d32a64925ac4b230397bd5799 schema:affiliation https://www.grid.ac/institutes/grid.24434.35
116 schema:familyName Housh
117 schema:givenName Terry J.
118 rdf:type schema:Person
119 N75b243fb84ea4dbfa509c8c9d082d314 rdf:first N93fbfb63c90f4232a36e93781319ac99
120 rdf:rest Ncbe527f02da4476398bc6b84a236fdc9
121 N76a3cdd2043045fa9ad6a194fdf2bbfd schema:issueNumber 1
122 rdf:type schema:PublicationIssue
123 N89e4ec69a84c407891650ebf5b50aae5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Resins, Plant
125 rdf:type schema:DefinedTerm
126 N909dacb08bec4c769b59956f8dd46a94 rdf:first Nf55dbd0b458a49cd97cf6cdd4a00597c
127 rdf:rest N75b243fb84ea4dbfa509c8c9d082d314
128 N93fbfb63c90f4232a36e93781319ac99 schema:affiliation https://www.grid.ac/institutes/grid.24434.35
129 schema:familyName Smith
130 schema:givenName Cory M.
131 rdf:type schema:Person
132 N981a7a2a962943d5adc9310205d9a80b schema:affiliation https://www.grid.ac/institutes/grid.24434.35
133 schema:familyName Johnson
134 schema:givenName Glen O.
135 rdf:type schema:Person
136 Na81b3b83be05420f935960b5f27a3fae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Dietary Supplements
138 rdf:type schema:DefinedTerm
139 Nac54ae92f6a44158b13bb39570999abe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Isometric Contraction
141 rdf:type schema:DefinedTerm
142 Nad985838e9284a39bbe540898ee67eeb schema:name pubmed_id
143 schema:value 30728074
144 rdf:type schema:PropertyValue
145 Ncbe527f02da4476398bc6b84a236fdc9 rdf:first N3e74688fd5114e20bba8ef3c23ba0b7e
146 rdf:rest N3531228b9a68472d96caaa876a8098df
147 Nd90e7cf4a0fb4ec5899df1bd94ad9ff3 schema:name readcube_id
148 schema:value dd8b05c3e6b5432db5589e75d0eb8b8f89b30a682400cbefb962bff3d121b809
149 rdf:type schema:PropertyValue
150 Ne16f353c601d4356a292a1738faa17a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Muscle Fatigue
152 rdf:type schema:DefinedTerm
153 Nef5a3b7ff5f74b12beedab4abce40b43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Male
155 rdf:type schema:DefinedTerm
156 Nf55dbd0b458a49cd97cf6cdd4a00597c schema:affiliation https://www.grid.ac/institutes/grid.24434.35
157 schema:familyName Hill
158 schema:givenName Ethan C.
159 rdf:type schema:Person
160 Nf625a340bf3f4c8980128fe0402bdcd4 rdf:first N0d893b1cfc2b47b8bdde4aae6272c2ab
161 rdf:rest N49b9b1cc128445a08c530cdf398178a0
162 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
163 schema:name Medical and Health Sciences
164 rdf:type schema:DefinedTerm
165 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
166 schema:name Clinical Sciences
167 rdf:type schema:DefinedTerm
168 sg:journal.1034609 schema:issn 1550-2783
169 schema:name Journal of the International Society of Sports Nutrition
170 rdf:type schema:Periodical
171 sg:pub.10.1007/bf00433399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004218254
172 https://doi.org/10.1007/bf00433399
173 rdf:type schema:CreativeWork
174 sg:pub.10.1007/s004210050174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046019065
175 https://doi.org/10.1007/s004210050174
176 rdf:type schema:CreativeWork
177 sg:pub.10.1007/s40279-017-0719-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1084040158
178 https://doi.org/10.1007/s40279-017-0719-x
179 rdf:type schema:CreativeWork
180 sg:pub.10.1186/s12970-015-0104-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029940448
181 https://doi.org/10.1186/s12970-015-0104-9
182 rdf:type schema:CreativeWork
183 sg:pub.10.2165/00007256-200434010-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036869835
184 https://doi.org/10.2165/00007256-200434010-00005
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1002/ptr.5018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017990657
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/j.jep.2011.04.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007707774
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.mehy.2015.12.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019122106
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1037/h0076767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001593503
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1055/s-0043-106438 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085276892
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1055/s-2007-1025014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057495865
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1056/nejm199607043350101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050135146
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1074/jbc.m110709200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039390271
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1080/026404199365911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034946125
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1080/15438627.2011.608046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078461306
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1089/jmf.2016.0010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051586258
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1093/oxfordjournals.bmb.a072570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076571174
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1097/00002060-200211001-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045216961
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1111/and.12482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036345085
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1111/andr.12454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100074721
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1111/j.1748-1716.1980.tb06495.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040214471
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1113/jp275450 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104900296
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1113/jphysiol.2002.035089 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036697541
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1152/japplphysiol.01174.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001089248
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1249/00005768-199508000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032481013
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1515/cclm.1985.23.9.515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034543638
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1519/00124278-200502000-00038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050726775
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1519/jsc.0b013e31816605a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003859142
231 rdf:type schema:CreativeWork
232 https://www.grid.ac/institutes/grid.24434.35 schema:alternateName University of Nebraska–Lincoln
233 schema:name Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska – Lincoln, 110 Ruth Leverton Hall, 68583-0806, Lincoln, NE, USA
234 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...