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    "description": "BackgroundThe effects of protein supplementation on muscle thickness and strength seem largely dependent on its composition. The current study aimed at comparing the impact of an oral supplementation with vegetable Pea protein (NUTRALYS\u00ae) vs. Whey protein and Placebo on biceps brachii muscle thickness and strength after a 12-week resistance training program.MethodsOne hundred and sixty one males, aged 18 to 35\u00a0years were enrolled in the study and underwent 12\u00a0weeks of resistance training on upper limb muscles. According to randomization, they were included in the Pea protein (n\u2009=\u200953), Whey protein (n\u2009=\u200954) or Placebo (n\u2009=\u200954) group. All had to take 25\u00a0g of the proteins or placebo twice a day during the 12-week training period. Tests were performed on biceps muscles at inclusion (D0), mid (D42) and post training (D84). Muscle thickness was evaluated using ultrasonography, and strength was measured on an isokinetic dynamometer.ResultsResults showed a significant time effect for biceps brachii muscle thickness (P\u2009<\u20090.0001). Thickness increased from 24.9\u2009\u00b1\u20093.8\u00a0mm to 26.9\u2009\u00b1\u20094.1\u00a0mm and 27.3\u2009\u00b1\u20094.4\u00a0mm at D0, D42 and D84, respectively, with only a trend toward significant differences between groups (P\u2009=\u20090.09). Performing a sensitivity study on the weakest participants (with regards to strength at inclusion), thickness increases were significantly different between groups (+20.2\u2009\u00b1\u200912.3%, +15.6\u2009\u00b1\u200913.5% and +8.6\u2009\u00b1\u20097.3% for Pea, Whey and Placebo, respectively; P\u2009<\u20090.05). Increases in thickness were significantly greater in the Pea group as compared to Placebo whereas there was no difference between Whey and the two other conditions. Muscle strength also increased with time with no statistical difference between groups.ConclusionsIn addition to an appropriate training, the supplementation with pea protein promoted a greater increase of muscle thickness as compared to Placebo and especially for people starting or returning to a muscular strengthening. Since no difference was obtained between the two protein groups, vegetable pea proteins could be used as an alternative to Whey-based dietary products.Trial registrationThe present trial has been registered at ClinicalTrials.gov (NCT02128516).", 
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